Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of CNMD mRNA | CTD | PMID:26496021 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of CNMD mRNA] and Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to CNMD promoter] | CTD | PMID:16891777 and PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CNMD mRNA | CTD | PMID:32109520 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CNMD mRNA | CTD | PMID:16891777 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Cnmd (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of CNMD mRNA | CTD | PMID:26377647 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-palmitoylglycerol | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of CNMD mRNA | CTD | PMID:37199045 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:19467301 | 3,7-dihydropurine-6-thione | decreases expression | EXP | | 6480464 | Mercaptopurine results in decreased expression of CNMD mRNA | CTD | PMID:23358152 | 4,4'-sulfonyldiphenol | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | bisphenol S results in decreased expression of CNMD mRNA | CTD | PMID:30951980 | 4-hydroxyphenyl retinamide | increases expression | ISO | Cnmd (Mus musculus) | 6480464 | Fenretinide results in increased expression of CNMD mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CNMD mRNA | CTD | PMID:24780913 | actinomycin D | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein] | CTD | PMID:19525446 | aflatoxin B1 | decreases methylation | ISO | CNMD (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of CNMD gene | CTD | PMID:27153756 | all-trans-retinoic acid | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in increased expression of CNMD mRNA and [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CNMD mRNA | CTD | PMID:30951980 and PMID:36189433 | all-trans-retinoic acid | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | Tretinoin results in decreased expression of CNMD mRNA | CTD | PMID:36189433 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CNMD mRNA | CTD | PMID:16483693 | arsenous acid | decreases expression | ISO | CNMD (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CNMD mRNA | CTD | PMID:18414637 | belinostat | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | belinostat results in increased expression of CNMD mRNA | CTD | PMID:26272509 | belinostat | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA | CTD | PMID:27188386 | benzo[a]pyrene | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | Benzo(a)pyrene affects the reaction [AHR protein binds to CNMD promoter] | CTD | PMID:19654925 | benzo[a]pyrene | decreases methylation | ISO | CNMD (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LECT1 exon | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | CNMD (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of CNMD mRNA | CTD | PMID:31163220 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of CNMD mRNA | CTD | PMID:26496021 | bisphenol A | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in increased expression of CNMD mRNA | CTD | PMID:30951980 | bisphenol A | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | bisphenol A results in decreased expression of CNMD mRNA | CTD | PMID:30951980 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CNMD mRNA | CTD | PMID:25181051 more ... | bisphenol F | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | bisphenol F results in decreased expression of CNMD mRNA | CTD | PMID:30951980 | cadmium dichloride | increases expression | ISO | Cnmd (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of CNMD mRNA | CTD | PMID:24982889 | carbamazepine | affects expression | ISO | CNMD (Homo sapiens) | 6480464 | Carbamazepine affects the expression of CNMD mRNA | CTD | PMID:25979313 | CGP 52608 | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LECT1 gene] | CTD | PMID:28238834 | diarsenic trioxide | decreases expression | ISO | CNMD (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of CNMD mRNA | CTD | PMID:18414637 | dorsomorphin | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | entinostat | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | entinostat results in increased expression of CNMD mRNA | CTD | PMID:26272509 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of CNMD mRNA | CTD | PMID:30307764 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of CNMD gene | CTD | PMID:22079235 | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of CNMD mRNA | CTD | PMID:24395379 | hydroquinone | increases response to substance | ISO | CNMD (Homo sapiens) | 6480464 | CNMD protein results in increased susceptibility to hydroquinone | CTD | PMID:19525446 | hydroquinone | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein] more ... | CTD | PMID:19525446 | hydroquinone | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | hydroquinone results in increased expression of CNMD mRNA | CTD | PMID:19525446 | indometacin | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | Indomethacin results in increased expression of CNMD mRNA | CTD | PMID:24737281 | inulin | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CNMD mRNA | CTD | PMID:36331819 | lead diacetate | affects expression | EXP | | 6480464 | lead acetate affects the expression of CNMD mRNA | CTD | PMID:22641619 | mercaptopurine | decreases expression | EXP | | 6480464 | Mercaptopurine results in decreased expression of CNMD mRNA | CTD | PMID:23358152 | metacetamol | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | 3-hydroxyacetanilide results in decreased expression of CNMD mRNA | CTD | PMID:18544908 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of CNMD mRNA | CTD | PMID:36189433 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of CNMD mRNA | CTD | PMID:36189433 | N-nitrosodiethylamine | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | Diethylnitrosamine results in decreased expression of CNMD mRNA | CTD | PMID:24535843 | panobinostat | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | panobinostat results in increased expression of CNMD mRNA | CTD | PMID:26272509 | panobinostat | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA | CTD | PMID:27188386 | paracetamol | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | Acetaminophen results in decreased expression of CNMD mRNA | CTD | PMID:18544908 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of CNMD mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | Cnmd (Mus musculus) | 6480464 | Phenobarbital results in increased expression of CNMD mRNA | CTD | PMID:19270015 more ... | phenobarbital | multiple interactions | ISO | Cnmd (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CNMD mRNA] | CTD | PMID:19482888 | phenylmercury acetate | decreases expression | ISO | CNMD (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of CNMD mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNMD mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of CNMD mRNA | CTD | PMID:18445702 | pirinixic acid | increases expression | ISO | Cnmd (Mus musculus) | 6480464 | pirinixic acid results in increased expression of CNMD mRNA | CTD | PMID:18301758 | propiconazole | increases expression | ISO | Cnmd (Mus musculus) | 6480464 | propiconazole results in increased expression of CNMD mRNA | CTD | PMID:21278054 | purine-6-thiol | decreases expression | EXP | | 6480464 | Mercaptopurine results in decreased expression of CNMD mRNA | CTD | PMID:23358152 | roxarsone | decreases expression | ISO | CNMD (Homo sapiens) | 6480464 | Roxarsone results in decreased expression of CNMD mRNA | CTD | PMID:18414637 | SB 431542 | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of CNMD mRNA | CTD | PMID:23221170 | tetrachloromethane | decreases expression | ISO | Cnmd (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of CNMD mRNA | CTD | PMID:27339419 and PMID:31919559 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of CNMD mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | trichostatin A results in increased expression of CNMD mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA | CTD | PMID:27188386 | triclosan | decreases expression | ISO | CNMD (Homo sapiens) | 6480464 | Triclosan results in decreased expression of CNMD mRNA | CTD | PMID:30510588 | triticonazole | increases expression | EXP | | 6480464 | triticonazole results in increased expression of CNMD mRNA | CTD | PMID:36084822 | valproic acid | affects expression | ISO | CNMD (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CNMD mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | CNMD (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CNMD mRNA | CTD | PMID:24383497 more ... | valproic acid | multiple interactions | ISO | CNMD (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CNMD mRNA | CTD | PMID:27188386 | |