Fgf14 (fibroblast growth factor 14) - Rat Genome Database

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Gene: Fgf14 (fibroblast growth factor 14) Rattus norvegicus
Analyze
Symbol: Fgf14
Name: fibroblast growth factor 14
RGD ID: 620165
Description: Enables growth factor activity. Acts upstream of or within several processes, including positive regulation of high voltage-gated calcium channel activity; regulation of postsynaptic membrane potential; and regulation of synaptic vesicle recycling. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal dominant cerebellar ataxia. Orthologous to human FGF14 (fibroblast growth factor 14); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,5,6,7-TETRABROMOBENZOTRIAZOLE.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FGF homologus factor 4b; FGF-14; Fhf4; fibroblast growth factor homologous factor 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815107,442,800 - 108,086,486 (-)NCBIGRCr8
mRatBN7.215101,045,033 - 101,679,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl15101,045,036 - 101,679,900 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx15105,001,581 - 105,221,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015106,090,629 - 106,309,568 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015103,017,877 - 103,236,826 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015110,382,274 - 111,077,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15110,385,217 - 110,612,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015113,762,507 - 114,450,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415109,057,275 - 109,297,945 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115109,073,054 - 109,313,725 (-)NCBI
Celera1599,789,847 - 100,014,689 (-)NCBICelera
Cytogenetic Map15q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 9 of 9 rows
Object Symbol
Species
Term
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Evidence
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Original Reference(s)
Fgf14RatAnal Atresia, Hypospadias, and Penoscrotal Inversion  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Anal atresia more ...ClinVarPMID:31690835
Fgf14Ratautistic disorder  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:25741868
Fgf14Ratautosomal dominant cerebellar ataxia  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Autosomal dominant cerebellar ataxiaClinVar 
Fgf14RatEvans Syndrome, Immunodeficiency, and Premature Immunosenescence associated with Tripeptidyl-Peptidase II Deficiency  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Evans syndrome more ...ClinVarPMID:25414442 and PMID:28492532
Fgf14Ratgenetic disease  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Fgf14Ratholoprosencephaly 5  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Holoprosencephaly 5ClinVarPMID:17274816 more ...
Fgf14Ratpropionic acidemia  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Propionic acidemiaClinVarPMID:28492532
Fgf14RatSpinocerebellar Ataxia 27A  ISOFGF14 (Homo sapiens)8554872ClinVar Annotator: match by term: Spinocerebellar ataxia 27AClinVarPMID:12489043 more ...
Fgf14Ratspinocerebellar ataxia type 27  ISOFGF14 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12489043 more ...
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Original Reference(s)
Fgf14Ratcartilage disease  ISOFGF14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:11241832
Fgf14Ratcognitive disorder  ISOFGF14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26089778
Fgf14Ratspinocerebellar ataxia type 27  ISOFGF14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26089778
Object Symbol
Species
Term
Qualifier
Evidence
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Original Reference(s)
Fgf14Ratspinocerebellar ataxia type 27  ISSFgf14 (Mus musculus)13592920OMIM:193003MouseDO 
Object Symbol
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Reference
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Original Reference(s)
Fgf14RatSpinocerebellar Ataxia 27A  ISOFGF14 (Homo sapiens)7240710 OMIM 
Fgf14RatSpinocerebellar Ataxia 27B  ISOFGF14 (Homo sapiens)7240710 OMIM 

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Object Symbol
Species
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Original Reference(s)
Fgf14Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of FGF14 mRNACTDPMID:29097150
Fgf14Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOFgf14 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Fgf14Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOFgf14 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Fgf14Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of FGF14 mRNACTDPMID:32109520
Fgf14Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether decreases expressionISOFGF14 (Homo sapiens)64804642 more ...CTDPMID:26705709
Fgf14Rat3,4-methylenedioxymethamphetamine decreases expressionISOFgf14 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of FGF14 mRNACTDPMID:20188158
Fgf14Rat4,4'-sulfonyldiphenol increases methylationISOFGF14 (Homo sapiens)6480464bisphenol S results in increased methylation of FGF14 geneCTDPMID:31601247
Fgf14Rat4,4'-sulfonyldiphenol affects methylationISOFgf14 (Mus musculus)6480464bisphenol S affects the methylation of FGF14 geneCTDPMID:31683443
Fgf14Rat4,5,6,7-TETRABROMOBENZOTRIAZOLE multiple interactionsEXP 64804644 more ...CTDPMID:26917740
Fgf14Ratacetohydrazide decreases expressionISOFgf14 (Mus musculus)6480464acetylhydrazine results in decreased expression of FGF14 mRNACTDPMID:15282401
Fgf14Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of FGF14 mRNACTDPMID:28959563
Fgf14Rataflatoxin B1 decreases methylationISOFGF14 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of FGF14 geneCTDPMID:27153756
Fgf14Rataflatoxin B1 affects methylationISOFGF14 (Homo sapiens)6480464Aflatoxin B1 affects the methylation of FGF14 intronCTDPMID:30157460
Fgf14RatAflatoxin B2 alpha decreases methylationISOFGF14 (Homo sapiens)6480464aflatoxin B2 results in decreased methylation of FGF14 intronCTDPMID:30157460
Fgf14Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of FGF14 mRNACTDPMID:16483693
Fgf14Ratantirheumatic drug decreases expressionISOFGF14 (Homo sapiens)6480464Antirheumatic Agents results in decreased expression of FGF14 mRNACTDPMID:24449571
Fgf14Ratarsenous acid decreases expressionISOFGF14 (Homo sapiens)6480464Arsenic Trioxide results in decreased expression of FGF14 mRNACTDPMID:26705709
Fgf14Ratbenzo[a]pyrene affects methylationISOFGF14 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of FGF14 intronCTDPMID:30157460
Fgf14Ratbenzo[a]pyrene decreases expressionISOFGF14 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of FGF14 mRNACTDPMID:32234424
Fgf14Ratbenzo[a]pyrene decreases methylationISOFGF14 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of FGF14 promoterCTDPMID:27901495

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Biological Process
1 to 12 of 12 rows

  
Object Symbol
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Original Reference(s)
Fgf14Ratadult locomotory behavior acts_upstream_of_or_withinISOFgf14 (Mus musculus)1624291MGI:109183 PMID:17678857RGDPMID:17678857
Fgf14Ratchemical synaptic transmission acts_upstream_of_or_withinISOFgf14 (Mus musculus)1624291MGI:109183 PMID:17678857RGDPMID:17678857
Fgf14Ratfibroblast growth factor receptor signaling pathway NOT|acts_upstream_of_or_withinISOFGF14 (Homo sapiens) and UniProtKB:Q92915-21624291 PMID:12815063RGDPMID:12815063
Fgf14RatJNK cascade acts_upstream_of_or_withinISOFGF14 (Homo sapiens) and UniProtKB:Q92915-21624291UniProtKB:Q9ERE9 and PMID:12815063RGDPMID:12815063
Fgf14Ratneurogenesis involved_inIBAFB:FBgn0014135 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgf14Ratneuromuscular process acts_upstream_of_or_withinISOFgf14 (Mus musculus)1624291MGI:109183 PMID:17678857RGDPMID:17678857
Fgf14Ratpositive regulation of high voltage-gated calcium channel activity acts_upstream_of_or_withinIMP 10047342PMID:23831029MGI 
Fgf14Ratpositive regulation of sodium ion transport acts_upstream_of_or_withinISOFgf14 (Mus musculus)1624291MGI:109183 PMID:17678857RGDPMID:17678857
Fgf14Ratregulation of postsynaptic membrane potential acts_upstream_of_or_withinIDA 10047342PMID:23831029MGI 
Fgf14Ratregulation of synaptic plasticity acts_upstream_of_or_withinIMP 10047342PMID:23831029MGI 
Fgf14Ratregulation of synaptic vesicle recycling acts_upstream_of_or_withinIMP 10047342PMID:23831029MGI 
Fgf14Ratsignal transduction involved_inIEAGO:00080831600115GO_REF:0000108GOCGO_REF:0000108
1 to 12 of 12 rows

Cellular Component

  
Object Symbol
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Original Reference(s)
Fgf14Ratcytoplasm is_active_inIBAMGI:109178 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgf14Ratcytosol located_inISOFgf14 (Mus musculus)1624291 PMID:10644718RGDPMID:10644718
Fgf14Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Fgf14Ratnucleus located_inISOFgf14 (Mus musculus)1624291 PMID:10644718RGDPMID:10644718
Fgf14Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Fgf14Ratnucleus is_active_inIBAMGI:109178 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Fgf14Ratsynapse located_inIEAGO:00072681600115GO_REF:0000108GOCGO_REF:0000108

Molecular Function

  

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
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Reference
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Original Reference(s)
Fgf14Ratmelanoma pathway  IEA 6907045 KEGGrno:05218
Fgf14Ratmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010

1 to 10 of 10 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Structural analysis of a mature hst-1 protein with transforming growth factor activity. Miyagawa K, etal., Biochem Biophys Res Commun 1991 Jan 15;174(1):404-10.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Structure and expression of a novel isoform of mouse FGF homologous factor (FHF)-4. Yamamoto S, etal., Biochim Biophys Acta 1998 May 29;1398(1):38-41.
10. FGF14 regulates presynaptic Ca2+ channels and synaptic transmission. Yan H, etal., Cell Rep. 2013 Jul 11;4(1):66-75. doi: 10.1016/j.celrep.2013.06.012. Epub 2013 Jul 3.
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PMID:10644718   PMID:12815063   PMID:17678857   PMID:23640885   PMID:25659151   PMID:33651884  



Fgf14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr815107,442,800 - 108,086,486 (-)NCBIGRCr8
mRatBN7.215101,045,033 - 101,679,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl15101,045,036 - 101,679,900 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx15105,001,581 - 105,221,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.015106,090,629 - 106,309,568 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.015103,017,877 - 103,236,826 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.015110,382,274 - 111,077,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15110,385,217 - 110,612,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015113,762,507 - 114,450,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415109,057,275 - 109,297,945 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.115109,073,054 - 109,313,725 (-)NCBI
Celera1599,789,847 - 100,014,689 (-)NCBICelera
Cytogenetic Map15q25NCBI
FGF14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3813101,710,804 - 102,402,443 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl13101,710,804 - 102,402,457 (-)EnsemblGRCh38hg38GRCh38
GRCh3713102,363,154 - 103,054,793 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3613101,173,036 - 101,852,125 (-)NCBINCBI36Build 36hg18NCBI36
Build 3413101,173,035 - 101,852,125NCBI
Celera1383,216,004 - 83,896,590 (-)NCBICelera
Cytogenetic Map13q33.1NCBI
HuRef1382,966,637 - 83,646,527 (-)NCBIHuRef
CHM1_113102,343,273 - 103,023,626 (-)NCBICHM1_1
T2T-CHM13v2.013100,926,801 - 101,618,453 (-)NCBIT2T-CHM13v2.0
Fgf14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914124,211,257 - 124,915,098 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14124,215,319 - 124,914,539 (-)EnsemblGRCm39 Ensembl
GRCm3814123,974,441 - 124,677,686 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14123,977,907 - 124,677,127 (-)EnsemblGRCm38mm10GRCm38
MGSCv3714124,377,513 - 125,076,349 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614123,113,087 - 123,860,355 (-)NCBIMGSCv36mm8
Celera14123,432,239 - 124,123,303 (-)NCBICelera
Cytogenetic Map14E5NCBI
cM Map1466.18NCBI
Fgf14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554048,705,112 - 9,325,117 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554048,704,344 - 9,329,917 (+)NCBIChiLan1.0ChiLan1.0
FGF14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214103,226,462 - 103,919,983 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan113101,893,411 - 102,587,258 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01382,869,491 - 83,563,099 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.113102,013,549 - 102,697,116 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl13102,016,568 - 102,696,330 (-)Ensemblpanpan1.1panPan2
FGF14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12251,379,799 - 51,983,662 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2251,380,788 - 51,982,849 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2251,160,800 - 51,763,369 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02251,830,679 - 52,434,436 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2251,830,715 - 52,433,639 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12251,482,297 - 52,083,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02251,490,701 - 52,099,973 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02251,538,733 - 52,140,689 (-)NCBIUU_Cfam_GSD_1.0
Fgf14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945186,718,451 - 187,350,642 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364728,602,365 - 9,227,600 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364728,601,968 - 9,233,704 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1170,251,446 - 70,422,192 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11170,251,374 - 70,861,941 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21177,550,629 - 77,720,414 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1380,304,996 - 80,978,292 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl380,309,110 - 80,500,510 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604636,809,470 - 37,514,918 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgf14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247939,021,579 - 9,638,740 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247939,021,538 - 9,641,651 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Fgf14
2961 total Variants

Predicted Target Of
Summary Value
Count of predictions:614
Count of miRNA genes:288
Interacting mature miRNAs:341
Transcripts:ENSRNOT00000041551, ENSRNOT00000075343
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
731177Uae26Urinary albumin excretion QTL 262.40.025urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1567588667101769107Rat
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat
631655Bp126Blood pressure QTL 1264arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1558156477101769107Rat

D15Got101  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215101,108,115 - 101,108,293 (+)MAPPERmRatBN7.2
Rnor_6.015110,445,357 - 110,445,534NCBIRnor6.0
Rnor_5.015113,824,284 - 113,824,461UniSTSRnor5.0
RGSC_v3.415109,130,420 - 109,130,598RGDRGSC3.4
RGSC_v3.415109,130,421 - 109,130,598UniSTSRGSC3.4
RGSC_v3.115109,146,201 - 109,146,378RGD
Celera1599,849,944 - 99,850,121UniSTS
RH 3.4 Map15743.9UniSTS
RH 3.4 Map15743.9RGD
RH 2.0 Map15623.4RGD
Cytogenetic Map15q25UniSTS
BF414602  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215101,046,068 - 101,046,177 (+)MAPPERmRatBN7.2
Rnor_6.015110,383,305 - 110,383,413NCBIRnor6.0
Rnor_5.015113,763,543 - 113,763,651UniSTSRnor5.0
RGSC_v3.415109,055,363 - 109,055,471UniSTSRGSC3.4
Celera1599,787,935 - 99,788,043UniSTS
RH 3.4 Map15743.49UniSTS
Cytogenetic Map15q25UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 41 113 53 51 25 20 25 6 158 83 93 33 59 26



Ensembl Acc Id: ENSRNOT00000041551   ⟹   ENSRNOP00000042838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl15101,045,036 - 101,274,056 (-)Ensembl
Rnor_6.0 Ensembl15110,385,217 - 110,612,681 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102677   ⟹   ENSRNOP00000088042
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl15101,045,036 - 101,679,900 (-)Ensembl
RefSeq Acc Id: NM_001411965   ⟹   NP_001398894
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,451,634 - 108,086,412 (-)NCBI
mRatBN7.215101,045,033 - 101,679,801 (-)NCBI
RefSeq Acc Id: NM_022223   ⟹   NP_071559
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,451,634 - 107,680,745 (-)NCBI
mRatBN7.215101,045,033 - 101,274,129 (-)NCBI
Rnor_6.015110,385,217 - 110,612,681 (-)NCBI
Rnor_5.015113,762,507 - 114,450,890 (-)NCBI
RGSC_v3.415109,057,275 - 109,297,945 (-)RGD
Celera1599,789,847 - 100,014,689 (-)RGD
Sequence:
RefSeq Acc Id: XM_039093636   ⟹   XP_038949564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,442,800 - 108,086,486 (-)NCBI
mRatBN7.215101,045,038 - 101,679,888 (-)NCBI
RefSeq Acc Id: XM_039093639   ⟹   XP_038949567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,442,800 - 108,085,538 (-)NCBI
mRatBN7.215101,045,038 - 101,678,913 (-)NCBI
RefSeq Acc Id: XM_063274611   ⟹   XP_063130681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,442,800 - 107,861,474 (-)NCBI
RefSeq Acc Id: XM_063274612   ⟹   XP_063130682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,442,800 - 107,861,474 (-)NCBI
RefSeq Acc Id: XM_063274613   ⟹   XP_063130683
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,442,800 - 107,861,474 (-)NCBI
RefSeq Acc Id: XM_063274614   ⟹   XP_063130684
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr815107,442,800 - 108,085,596 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_071559   ⟸   NM_022223
- Peptide Label: isoform 1
- UniProtKB: Q8R5L7 (UniProtKB/Swiss-Prot),   A6HUN3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000042838   ⟸   ENSRNOT00000041551
RefSeq Acc Id: XP_038949564   ⟸   XM_039093636
- Peptide Label: isoform X1
- UniProtKB: Q794I6 (UniProtKB/TrEMBL),   A6HUN2 (UniProtKB/TrEMBL),   A0A8I6A9Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949567   ⟸   XM_039093639
- Peptide Label: isoform X2
- UniProtKB: Q8R4X0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088042   ⟸   ENSRNOT00000102677

Name Modeler Protein Id AA Range Protein Structure
AF-Q8R5L7-F1-model_v2 AlphaFold Q8R5L7 1-247 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-12327 BioCyc
Ensembl Genes ENSRNOG00000009288 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000041551 ENTREZGENE
  ENSRNOT00000041551.6 UniProtKB/Swiss-Prot
  ENSRNOT00000102677 ENTREZGENE
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot
InterPro Fibroblast_GF_fam UniProtKB/Swiss-Prot
  IL1/FGF UniProtKB/Swiss-Prot
KEGG Report rno:63851 UniProtKB/Swiss-Prot
NCBI Gene 63851 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot
Pfam FGF UniProtKB/Swiss-Prot
PhenoGen Fgf14 PhenoGen
PRINTS HBGFFGF UniProtKB/Swiss-Prot
  IL1HBGF UniProtKB/Swiss-Prot
PROSITE HBGF_FGF UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009288 RatGTEx
SMART FGF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot
UniProt A0A8I6A9Y8 ENTREZGENE, UniProtKB/TrEMBL
  A6HUN2 ENTREZGENE, UniProtKB/TrEMBL
  A6HUN3 ENTREZGENE, UniProtKB/TrEMBL
  FGF14_RAT UniProtKB/Swiss-Prot
  Q794I6 ENTREZGENE
  Q8R4X0 ENTREZGENE, UniProtKB/TrEMBL
  Q8R5L7 ENTREZGENE
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Fgf14  fibroblast growth factor 14      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Fgf14  fibroblast growth factor 14      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_product member of the fibroblast growth factor (FGF) family 632810
gene_protein 148 amino acids 708320