Nnat (neuronatin) - Rat Genome Database

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Gene: Nnat (neuronatin) Rattus norvegicus
Analyze
Symbol: Nnat
Name: neuronatin
RGD ID: 620155
Description: Involved in neuron differentiation. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human NNAT (neuronatin); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC156562; neuronatin alpha; Peg5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,646,373 - 166,648,845 (+)NCBIGRCr8
mRatBN7.23146,225,941 - 146,228,868 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,226,407 - 146,228,834 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,051,744 - 150,054,205 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03158,552,933 - 158,555,392 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,294,850 - 156,297,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,043,873 - 154,046,334 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03161,553,358 - 161,557,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,269,404 - 148,271,781 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,175,312 - 148,177,690 (+)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular cloning of a novel mRNA (neuronatin) that is highly expressed in neonatal mammalian brain. Joseph R, etal., Biochem Biophys Res Commun 1994 Jun 30;201(3):1227-34.
4. Neuronatin mRNA: alternatively spliced forms of a novel brain-specific mammalian developmental gene. Joseph R, etal., Brain Res 1995 Aug 28;690(1):92-8.
5. Neuronatin mRNA in PC12 cells: downregulation by nerve growth factor. Joseph R, etal., Brain Res 1996 Oct 28;738(1):32-8.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Identification of cell-specific messenger ribonucleic acids in oxytocinergic and vasopressinergic magnocellular neurons in rat supraoptic nucleus by single-cell differential hybridization. Yamashita M, etal., Endocrinology 2002 Nov;143(11):4464-76.
Additional References at PubMed
PMID:12477932   PMID:15793245   PMID:19851307   PMID:20509861   PMID:21935485   PMID:24370184   PMID:30869556   PMID:31805566  


Genomics

Comparative Map Data
Nnat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,646,373 - 166,648,845 (+)NCBIGRCr8
mRatBN7.23146,225,941 - 146,228,868 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,226,407 - 146,228,834 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,051,744 - 150,054,205 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03158,552,933 - 158,555,392 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,294,850 - 156,297,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,043,873 - 154,046,334 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03161,553,358 - 161,557,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,269,404 - 148,271,781 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,175,312 - 148,177,690 (+)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBICelera
Cytogenetic Map3q42NCBI
NNAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382037,521,250 - 37,523,690 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2037,521,206 - 37,523,690 (+)EnsemblGRCh38hg38GRCh38
GRCh372036,149,652 - 36,152,092 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362035,583,021 - 35,585,506 (+)NCBINCBI36Build 36hg18NCBI36
Build 342035,583,020 - 35,585,502NCBI
Celera2032,856,869 - 32,859,355 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2032,885,325 - 32,887,812 (+)NCBIHuRef
CHM1_12036,052,423 - 36,054,893 (+)NCBICHM1_1
T2T-CHM13v2.02039,245,345 - 39,247,787 (+)NCBIT2T-CHM13v2.0
Nnat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392157,401,936 - 157,404,445 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2157,401,998 - 157,404,442 (+)EnsemblGRCm39 Ensembl
GRCm382157,560,078 - 157,562,525 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2157,560,078 - 157,562,522 (+)EnsemblGRCm38mm10GRCm38
MGSCv372157,385,846 - 157,388,258 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,251,564 - 157,253,945 (+)NCBIMGSCv36mm8
Celera2163,504,157 - 163,506,569 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.4NCBI
Nnat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544519,121,164 - 19,125,514 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544519,121,164 - 19,125,514 (-)NCBIChiLan1.0ChiLan1.0
NNAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22143,246,341 - 43,251,217 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12043,239,925 - 43,244,315 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,842,071 - 33,845,575 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,955,233 - 34,959,493 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,955,234 - 34,959,493 (+)Ensemblpanpan1.1panPan2
NNAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,119,153 - 26,121,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,118,991 - 26,120,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2425,764,843 - 25,767,256 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02426,815,822 - 26,818,235 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,815,835 - 26,817,449 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,091,104 - 26,093,520 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,198,494 - 26,200,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02426,686,053 - 26,688,469 (+)NCBIUU_Cfam_GSD_1.0
Nnat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,007,353 - 175,009,820 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,739,664 - 3,742,154 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,739,664 - 3,744,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NNAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11740,625,990 - 40,629,523 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,042,960 - 46,045,928 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NNAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,229,765 - 26,232,249 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,230,696 - 26,232,127 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605075,102,293 - 75,105,653 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nnat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248422,122,968 - 2,125,490 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nnat
8 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:787
Count of miRNA genes:252
Interacting mature miRNAs:321
Transcripts:ENSRNOT00000034166, ENSRNOT00000068863, ENSRNOT00000072502
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
5686842Rf59Renal function QTL 59urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)3140069424146976080Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat

Markers in Region
BI286603  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,606 - 146,228,775 (+)MAPPERmRatBN7.2
Rnor_6.03154,046,073 - 154,046,241NCBIRnor6.0
Rnor_5.03161,553,451 - 161,553,619UniSTSRnor5.0
RGSC_v3.43148,271,523 - 148,271,691UniSTSRGSC3.4
Celera3144,932,575 - 144,932,743UniSTS
RH 3.4 Map31352.6UniSTS
Cytogenetic Map3q42UniSTS
AA858569  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,607 - 146,228,827 (+)MAPPERmRatBN7.2
Rnor_6.03154,046,074 - 154,046,293NCBIRnor6.0
Rnor_5.03161,553,399 - 161,553,618UniSTSRnor5.0
RGSC_v3.43148,271,524 - 148,271,743UniSTSRGSC3.4
Celera3144,932,576 - 144,932,795UniSTS
RH 3.4 Map31353.3UniSTS
Cytogenetic Map3q42UniSTS
BF413147  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,150 - 146,228,302 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,617 - 154,045,768NCBIRnor6.0
Rnor_5.03161,553,924 - 161,554,075UniSTSRnor5.0
RGSC_v3.43148,271,067 - 148,271,218UniSTSRGSC3.4
Celera3144,932,119 - 144,932,270UniSTS
RH 3.4 Map31354.1UniSTS
Cytogenetic Map3q42UniSTS
BI281696  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,368 - 146,228,531 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,835 - 154,045,997NCBIRnor6.0
Rnor_5.03161,553,695 - 161,553,857UniSTSRnor5.0
RGSC_v3.43148,271,285 - 148,271,447UniSTSRGSC3.4
Celera3144,932,337 - 144,932,499UniSTS
RH 3.4 Map31352.3UniSTS
Cytogenetic Map3q42UniSTS
Nnat  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,077 - 146,228,693 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,544 - 154,046,159NCBIRnor6.0
Rnor_5.03161,553,533 - 161,554,148UniSTSRnor5.0
RGSC_v3.43148,270,994 - 148,271,609UniSTSRGSC3.4
Celera3144,932,046 - 144,932,661UniSTS
Cytogenetic Map3q42UniSTS
Nnat  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,502 - 146,228,697 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,969 - 154,046,163NCBIRnor6.0
Rnor_5.03161,553,529 - 161,553,723UniSTSRnor5.0
RGSC_v3.43148,271,419 - 148,271,613UniSTSRGSC3.4
Celera3144,932,471 - 144,932,665UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 51
Medium 3 26 24 12 4 12 2 2 23 24 31 11 2
Low 17 31 27 15 27 6 9 11 10 6
Below cutoff 2 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_181687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC127473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB711943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY315493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM037467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U08290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000034166   ⟹   ENSRNOP00000034212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,226,416 - 146,228,834 (+)Ensembl
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000072502   ⟹   ENSRNOP00000064325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,226,407 - 146,228,834 (+)Ensembl
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098078   ⟹   ENSRNOP00000096996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,226,416 - 146,228,108 (+)Ensembl
RefSeq Acc Id: NM_001270867   ⟹   NP_001257796
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053601   ⟹   NP_446053
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
RGSC_v3.43148,269,404 - 148,271,781 (+)RGD
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: NM_181687   ⟹   NP_859015
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
RGSC_v3.43148,269,404 - 148,271,781 (+)RGD
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073089
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008762390   ⟹   XP_008760612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,383 - 166,648,845 (+)NCBI
mRatBN7.23146,225,941 - 146,228,868 (+)NCBI
Rnor_6.03154,043,878 - 154,045,574 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063284795   ⟹   XP_063140865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,373 - 166,648,845 (+)NCBI
RefSeq Acc Id: NP_446053   ⟸   NM_053601
- Peptide Label: isoform alpha
- UniProtKB: A0JPK6 (UniProtKB/Swiss-Prot),   Q62663 (UniProtKB/Swiss-Prot),   Q62649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_859015   ⟸   NM_181687
- Peptide Label: isoform beta
- UniProtKB: Q62649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257796   ⟸   NM_001270867
- Peptide Label: isoform 3
- UniProtKB: Q62649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008760612   ⟸   XM_008762390
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QVS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000064325   ⟸   ENSRNOT00000072502
RefSeq Acc Id: ENSRNOP00000034212   ⟸   ENSRNOT00000034166
RefSeq Acc Id: ENSRNOP00000096996   ⟸   ENSRNOT00000098078
RefSeq Acc Id: XP_063140865   ⟸   XM_063284795
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62649-F1-model_v2 AlphaFold Q62649 1-81 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692613
Promoter ID:EPDNEW_R3138
Type:single initiation site
Name:Nnat_1
Description:neuronatin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03154,043,915 - 154,043,975EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620155 AgrOrtholog
BioCyc Gene G2FUF-47050 BioCyc
Ensembl Genes ENSRNOG00000024923 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034166 ENTREZGENE
  ENSRNOT00000034166.5 UniProtKB/TrEMBL
  ENSRNOT00000072502.4 UniProtKB/TrEMBL
  ENSRNOT00000098078.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8364201 IMAGE-MGC_LOAD
InterPro Neuronatin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94270 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156562 IMAGE-MGC_LOAD
NCBI Gene 94270 ENTREZGENE
PANTHER NEURONATIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15285 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nnat PhenoGen
RatGTEx ENSRNOG00000024923 RatGTEx
UniProt A0A8I6AR75_RAT UniProtKB/TrEMBL
  A0A8L2QVS0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UKY2_RAT UniProtKB/TrEMBL
  A0JPK6 ENTREZGENE
  A6JWT6_RAT UniProtKB/TrEMBL
  A6JWT7_RAT UniProtKB/TrEMBL
  A6JWT8_RAT UniProtKB/TrEMBL
  A6JWU0_RAT UniProtKB/TrEMBL
  NNAT_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q62663 ENTREZGENE
UniProt Secondary A0JPK6 UniProtKB/Swiss-Prot
  Q62663 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Nnat  neuronatin      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Nnat  neuronatin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression preferentially found in vasopressin (VP)-expressing magnocellular neurons (MCNs) 628363
gene_expression expressed in thyroid tumors 628363
gene_expression strongly expressed in neonatal rat brain, with a subsequent decreased expression in juveniles and adults; expressed in endocrine cells, including pancreatic b-cells and PC-12 cells 628363
gene_homology homologous to PMP-1, an H+-ATPase subunit 628363
gene_mapping gene maps to distal chromosome 2 in an imprinting region where mutations can lead to developmental abnormalities 628363
gene_process may mediate regulation of ions during brain development 628363
gene_protein 54 and 81 kDa 628363
gene_protein 81 amino acids 729024
gene_regulation gene is paternally expressed and imprinted 628363
gene_transcript contains three exons producing two alternatively spliced mRNA 628363