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Gene: Acrv1 (acrosomal vesicle protein 1) Rattus norvegicus

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Symbol:

Acrv1

Name:

acrosomal vesicle protein 1

RGD ID:

620153

Description:

Predicted to be located in acrosomal vesicle. Orthologous to human ACRV1 (acrosomal vesicle protein 1); INTERACTS WITH ammonium chloride; bisphenol A; cypermethrin.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

acrosomal protein SP-10; Sp10; sperm protein 10

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACRV1 (acrosomal vesicle protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Acrv1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Acrv1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACRV1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACRV1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Acrv1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACRV1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACRV1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Acrv1 (acrosomal vesicle protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Acrv1 (acrosomal vesicle protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ACRV1 (acrosomal vesicle protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	44,593,246 - 44,598,823 (+)	NCBI		GRCr8
mRatBN7.2	8	36,404,394 - 36,409,971 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	36,404,394 - 36,424,959 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	40,413,540 - 40,419,115 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	38,696,596 - 38,702,171 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	36,559,482 - 36,565,057 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	39,164,991 - 39,170,568 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	39,164,916 - 39,170,736 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	39,167,849 - 39,173,426 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	37,938,151 - 37,943,728 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	37,946,916 - 37,952,494 (+)	NCBI
Celera	8	38,031,165 - 38,036,742 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acrv1	Rat	chromosome 11 partial duplication syndrome		ISO	ACRV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Distal trisomy 11q	ClinVar	PMID:25741868
Acrv1	Rat	Dwarfism		ISO	ACRV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Short stature	ClinVar	PMID:32581362
Acrv1	Rat	holoprosencephaly 11		ISO	ACRV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Holoprosencephaly 11	ClinVar	PMID:28492532
Acrv1	Rat	Jacobsen Syndrome		ISO	ACRV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Paris-Trousseau thrombocytopenia	ClinVar	PMID:32581362
Acrv1	Rat	prostate cancer		ISO	ACRV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Malignant tumor of prostate	ClinVar	PMID:23265383
Acrv1	Rat	schizophrenia		ISO	ACRV1 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106 and PMID:30208311

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acrv1	Rat	17alpha-ethynylestradiol	affects expression	ISO	Acrv1 (Mus musculus)	6480464	Ethinyl Estradiol affects the expression of ACRV1 mRNA	CTD	PMID:17555576
Acrv1	Rat	ammonium chloride	affects expression	EXP		6480464	Ammonium Chloride affects the expression of ACRV1 mRNA	CTD	PMID:16483693
Acrv1	Rat	amphotericin B	increases expression	ISO	ACRV1 (Homo sapiens)	6480464	Amphotericin B analog results in increased expression of ACRV1 mRNA	CTD	PMID:28534445
Acrv1	Rat	aristolochic acid A	increases expression	ISO	ACRV1 (Homo sapiens)	6480464	aristolochic acid I results in increased expression of ACRV1 mRNA	CTD	PMID:33212167
Acrv1	Rat	atrazine	increases expression	ISO	ACRV1 (Homo sapiens)	6480464	Atrazine results in increased expression of ACRV1 mRNA	CTD	PMID:22378314
Acrv1	Rat	benzo[a]pyrene	decreases methylation	ISO	ACRV1 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased methylation of ACRV1 promoter	CTD	PMID:27901495
Acrv1	Rat	benzo[a]pyrene	increases methylation	ISO	ACRV1 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of ACRV1 exon	CTD	PMID:27901495
Acrv1	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ACRV1 mRNA	CTD	PMID:25181051
Acrv1	Rat	butanal	decreases expression	ISO	ACRV1 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of ACRV1 mRNA	CTD	PMID:26079696
Acrv1	Rat	CGP 52608	multiple interactions	ISO	ACRV1 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to ACRV1 gene]	CTD	PMID:28238834
Acrv1	Rat	cypermethrin	decreases expression	EXP		6480464	cypermethrin results in decreased expression of ACRV1 mRNA	CTD	PMID:35605701
Acrv1	Rat	dibutyl phthalate	affects expression	ISO	Acrv1 (Mus musculus)	6480464	Dibutyl Phthalate affects the expression of ACRV1 mRNA	CTD	PMID:34280466
Acrv1	Rat	diethylstilbestrol	decreases expression	EXP		6480464	Diethylstilbestrol results in decreased expression of ACRV1 mRNA	CTD	PMID:35605701
Acrv1	Rat	lead(0)	decreases expression	ISO	ACRV1 (Homo sapiens)	6480464	Lead results in decreased expression of ACRV1 mRNA	CTD	PMID:19921347
Acrv1	Rat	paracetamol	decreases expression	ISO	ACRV1 (Homo sapiens)	6480464	Acetaminophen results in decreased expression of ACRV1 mRNA	CTD	PMID:26690555
Acrv1	Rat	pirinixic acid	multiple interactions	ISO	Acrv1 (Mus musculus)	6480464	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of ACRV1 mRNA	CTD	PMID:19710929
Acrv1	Rat	propanal	decreases expression	ISO	ACRV1 (Homo sapiens)	6480464	propionaldehyde results in decreased expression of ACRV1 mRNA	CTD	PMID:26079696
Acrv1	Rat	silicon dioxide	decreases expression	ISO	ACRV1 (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of ACRV1 mRNA	CTD	PMID:25895662
Acrv1	Rat	sodium fluoride	increases expression	ISO	Acrv1 (Mus musculus)	6480464	Sodium Fluoride results in increased expression of ACRV1 mRNA	CTD	PMID:27862939
Acrv1	Rat	tamoxifen	affects expression	ISO	Acrv1 (Mus musculus)	6480464	Tamoxifen affects the expression of ACRV1 mRNA	CTD	PMID:17555576

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acrv1	Rat	acrosomal vesicle	located_in	ISO	Acrv1 (Mus musculus)	1624291	PMID:1591350 and PMID:16093322	RGD	PMID:1591350 and PMID:16093322

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Acrv1	Rat	protein binding	enables	ISO	ACRV1 (Homo sapiens)	1624291	UniProtKB:P50897 more ...	RGD	PMID:32814053

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
3.	Complementary deoxyribonucleic acid cloning and characterization of mSP-10: the mouse homologue of human acrosomal protein SP-10.	Reddi PP, etal., Biol Reprod 1995 Oct;53(4):873-81.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

PMID:1591350	PMID:16093322

Acrv1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	44,593,246 - 44,598,823 (+)	NCBI		GRCr8
mRatBN7.2	8	36,404,394 - 36,409,971 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	36,404,394 - 36,424,959 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	40,413,540 - 40,419,115 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	38,696,596 - 38,702,171 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	36,559,482 - 36,565,057 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	39,164,991 - 39,170,568 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	39,164,916 - 39,170,736 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	39,167,849 - 39,173,426 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	37,938,151 - 37,943,728 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	37,946,916 - 37,952,494 (+)	NCBI
Celera	8	38,031,165 - 38,036,742 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

ACRV1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	125,671,522 - 125,680,847 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	125,671,522 - 125,680,874 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	125,541,417 - 125,550,742 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	125,047,439 - 125,056,152 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	125,047,439 - 125,056,152	NCBI
Celera	11	122,702,479 - 122,711,196 (-)	NCBI		Celera
Cytogenetic Map	11	q24.2	ENTREZGENE
HuRef	11	121,483,607 - 121,492,216 (-)	NCBI		HuRef
CHM1_1	11	125,428,367 - 125,436,930 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	125,700,163 - 125,709,487 (-)	NCBI		T2T-CHM13v2.0

Acrv1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	36,604,550 - 36,610,139 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	36,604,516 - 36,610,139 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	36,693,220 - 36,698,845 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	36,693,220 - 36,698,843 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	36,500,805 - 36,506,422 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	36,442,921 - 36,448,515 (+)	NCBI		MGSCv36	mm8
Celera	9	33,896,072 - 33,901,689 (+)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	20.67	NCBI

Acrv1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	26,655,208 - 26,664,888 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	26,654,980 - 26,664,989 (-)	NCBI	ChiLan1.0	ChiLan1.0

ACRV1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	126,355,146 - 126,571,963 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	127,466,768 - 127,679,517 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	120,493,328 - 120,502,632 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	124,406,467 - 124,415,043 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	124,406,467 - 124,415,043 (-)	Ensembl	panpan1.1		panPan2

ACRV1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	8,844,035 - 8,850,557 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	8,846,834 - 8,850,567 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	8,889,045 - 8,895,554 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	8,786,609 - 8,793,131 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	8,786,621 - 8,793,141 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	8,856,314 - 8,862,816 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	8,826,217 - 8,832,727 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	8,862,816 - 8,869,330 (+)	NCBI		UU_Cfam_GSD_1.0

Acrv1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	107,799,566 - 107,806,117 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936743	2,047,383 - 2,053,589 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACRV1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	52,803,381 - 52,809,975 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	52,803,378 - 52,809,975 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	58,456,597 - 58,463,195 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACRV1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	116,812,667 - 116,821,625 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	116,812,726 - 116,821,073 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	9,249,490 - 9,258,435 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Acrv1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624927	1,645,923 - 1,653,291 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Acrv1
17 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	30
Count of miRNA genes:	28
Interacting mature miRNAs:	29
Transcripts:	ENSRNOT00000011309
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298065	Scl16	Serum cholesterol level QTL 16	3.8		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30856404	75856404	Rat
1578769	Uae31	Urinary albumin excretion QTL 31	3.3	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	30848154	101699754	Rat
11556286	Cm81	Cardiac mass QTL 81		0.01	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	30848154	61290444	Rat
1578765	Klgr1	Kidney lesion grade QTL 1	3.3	0.0001	kidney morphology trait (VT:0002135)	organ lesion measurement (CMO:0000677)	8	30848154	101699754	Rat
1582222	Epfw2	Epididymal fat weight QTL 2	3.2	0.0005	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	8	31737729	76737729	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
61464	Niddm11	Non-insulin dependent diabetes mellitus QTL 11	3.1	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	8	35582032	80582032	Rat
61337	Bp22	Blood pressure QTL 22	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	42692818	Rat
1578755	Pur5	Proteinuria QTL 5	3.3	0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	8	30848154	101699754	Rat
1300146	Rf17	Renal function QTL 17	2.9		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	8	28242912	73242912	Rat
8662823	Vetf5	Vascular elastic tissue fragility QTL 5	1.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	8	28242912	99525068	Rat
2313088	Bss75	Bone structure and strength QTL 75	3.1	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	8	30848154	82460899	Rat
1358896	Bp262	Blood pressure QTL 262	2.89		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	27205715	99103503	Rat
731182	Uae24	Urinary albumin excretion QTL 24	6.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	19331152	93965294	Rat
724514	Uae15	Urinary albumin excretion QTL 15	2.9		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	8	29502665	70386295	Rat
61353	Bp35	Blood pressure QTL 35		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	8	30848154	61290444	Rat
631842	Inf1	Infertility severity QTL 1	4.1	0.001	seminal gland mass (VT:0010524)	seminal vesicle wet weight (CMO:0001603)	8	22662330	67662330	Rat
1359033	Bp273	Blood pressure QTL 273			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	61290444	Rat
61358	Bp39	Blood pressure QTL 39	2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	35551938	80551938	Rat
1358907	Cm40	Cardiac mass QTL 40	1.89		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	8	27205715	99103503	Rat
1331744	Bp217	Blood pressure QTL 217	3.398		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	30848154	58482492	Rat
2316950	Scl66	Serum cholesterol level QTL 66	4.1		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	8	30848259	105647037	Rat
1358892	Kidm26	Kidney mass QTL 26	3.69		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	8	27205715	99103503	Rat
1359021	Bp271	Blood pressure QTL 271	1.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	26644912	46711092	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
61373	Mcs4	Mammary carcinoma susceptibility QTL 4	1.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	8	16290444	61290444	Rat
70206	Alc20	Alcohol consumption QTL 20	2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	8	30848154	40713225	Rat
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
2313057	Bss76	Bone structure and strength QTL 76	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	8	30848154	82460899	Rat
1549908	Neudeg1	Neurodegradation QTL 1	5.5	0	nervous system integrity trait (VT:0010566)	logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)	8	30188867	94457446	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
1331804	Cm30	Cardiac mass QTL 30	3.77443		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	8	28242912	53961020	Rat
2313067	Bss77	Bone structure and strength QTL 77	3.1	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	8	30848154	82460899	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	4705810	49705810	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	4705810	49705810	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	2097640	47097640	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	2097640	47097640	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	4705810	49705810	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	2097640	47097640	Rat
1558646	Swd5	Spike wave discharge measurement QTL 5	3.45	0.00036	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	8	14906751	59906751	Rat
2302278	Gluco36	Glucose level QTL 36	4.2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	29502665	50095447	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	2097640	47097640	Rat
631648	Stl5	Serum triglyceride level QTL 5	4	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	27205715	54998217	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
631271	Lecl1	Lens clarity QTL 1		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	8	18984168	84531599	Rat
2303564	Gluco43	Glucose level QTL 43	3		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	8	26130187	71130187	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
2313046	Bss78	Bone structure and strength QTL 78	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	8	30848154	82460899	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
2303572	Insul13	Insulin level QTL 13	2		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	8	26130187	71130187	Rat

U31992

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	36,410,018 - 36,410,150 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	39,170,616 - 39,170,747	NCBI	Rnor6.0
Rnor_5.0	8	39,173,474 - 39,173,605	UniSTS	Rnor5.0
RGSC_v3.4	8	37,943,776 - 37,943,907	UniSTS	RGSC3.4
Celera	8	38,030,986 - 38,031,117	UniSTS
Cytogenetic Map	8	q21	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
2	5	3	26	22	26	6	17	6	2	42	26	20	5	32	20


RefSeq Transcripts	NM_021747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ243484	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011309 ⟹ ENSRNOP00000011309

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	36,404,394 - 36,409,971 (+)	Ensembl
Rnor_6.0 Ensembl	8	39,164,916 - 39,170,736 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111144 ⟹ ENSRNOP00000088129

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	36,404,394 - 36,424,959 (+)	Ensembl

RefSeq Acc Id:

NM_021747 ⟹ NP_068515

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	44,593,246 - 44,598,823 (+)	NCBI
mRatBN7.2	8	36,404,394 - 36,409,971 (+)	NCBI
Rnor_6.0	8	39,164,991 - 39,170,568 (+)	NCBI
Rnor_5.0	8	39,167,849 - 39,173,426 (+)	NCBI
RGSC_v3.4	8	37,938,151 - 37,943,728 (+)	RGD
Celera	8	38,031,165 - 38,036,742 (-)	RGD

Sequence:

show sequence

ATCTTTCTTTTGCTAAATCAAAATGAAGGAGTTAATCTTACTGGGTCTTTATCTGCTTGGATCTTCCAGAGGAGCACCACCAGGTCAGCCAGATGAGCTTCTTGACTCTGTAGACCAAGCTTCTGTTC
AGCAACTTTCAAGTGAGTATTTCTCACTTGCAAACCCTTCAGATGCCAAAGCTTTATATGAAACTGCTTCAAGTGAGAAGACTCTGAGTGGTCATAGTTCAAGTGAACACGAATCAAGCGAGCATACT
GTAACTGAACATTCTGCAGGTGAGCACTCTTCAGGAGAACAGTCTTCAGAGCATATTTCAAGTGAGCACATGTCAGGAGAGCACCTGTCAGAACACACTTCTGGGGAGCATGCTTCTACCGAGCACAC
TTCCGGGGAGCACACTTCCGGGGAGCACACTTCAAGTGAACAACTTACAACTGAACAGTCCTCAAGTGACCAGTCTTCTGATGTATCTTCAGGCGAACAAGTTTCAGGTGAAAAGCTTGAAGAGGCAG
GTGAACAGGTGTCTGGCGAAGACAAAGGAAACGAAGTTATAAGTACACCACTTCCAAGCACGTCTTCAGGTGGGATAATAAATTGCCACACATGTGCTTATATGAATGAAGATGCAAAATGTCTCCGT
GGAGAAGGAATATGCACCACTCAAAATTCCCAGCAGTGCATGTTAAAGAAGATCTATGAAGGTGGAAAGCTCCAGTTCATGGTTCAAGGGTGTGAGAACATGTGCCCATCTATGAACCTCTTCTCTCA
TGGAACAAGAATGCAAATTATGTGCTGTCGTCATGAAGCTCTCTGCAACAAGGCCTAGA

hide sequence


Protein RefSeqs	NP_068515	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAB46086	(Get FASTA)	NCBI Sequence Viewer
	EDL84043	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011309
	ENSRNOP00000011309.1
	ENSRNOP00000088129.1

RefSeq Acc Id:	NP_068515 ⟸ NM_021747
- Peptide Label:	precursor
- UniProtKB:	Q9WUY6 (UniProtKB/TrEMBL), A6KRN3 (UniProtKB/TrEMBL), A0A8I6A9C9 (UniProtKB/TrEMBL), F7FIQ9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKELILLGLYLLGSSRGAPPGQPDELLDSVDQASVQQLSSEYFSLANPSDAKALYETASSEKTLSGHSSSEHESSEHTVTEHSAGEHSSGEQSSEHISSEHMSGEHLSEHTSGEHASTEHTSGEHTSG EHTSSEQLTTEQSSSDQSSDVSSGEQVSGEKLEEAGEQVSGEDKGNEVISTPLPSTSSGGIINCHTCAYMNEDAKCLRGEGICTTQNSQQCMLKKIYEGGKLQFMVQGCENMCPSMNLFSHGTRMQIM CCRHEALCNKA hide sequence

Ensembl Acc Id:

ENSRNOP00000011309 ⟸ ENSRNOT00000011309

Ensembl Acc Id:

ENSRNOP00000088129 ⟸ ENSRNOT00000111144

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WUY6-F1-model_v2	AlphaFold	Q9WUY6	1-267	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13695852

Promoter ID:

EPDNEW_R6377

Type:

initiation region

Name:

Acrv1_1

Description:

acrosomal vesicle protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	39,164,955 - 39,165,015	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-31104	BioCyc
Ensembl Genes	ENSRNOG00000008508	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011309	ENTREZGENE
	ENSRNOT00000011309.4	UniProtKB/TrEMBL
	ENSRNOT00000111144.1	UniProtKB/TrEMBL
InterPro	Acrosomal_SP-10-like	UniProtKB/TrEMBL
	LY6_UPA_recep-like	UniProtKB/TrEMBL
KEGG Report	rno:60353	UniProtKB/TrEMBL
NCBI Gene	60353	ENTREZGENE
PANTHER	ACROSOMAL PROTEIN SP-10	UniProtKB/TrEMBL
	URINARY PROTEIN RUP /ACROSOMAL PROTEIN SP-10	UniProtKB/TrEMBL
PhenoGen	Acrv1	PhenoGen
RatGTEx	ENSRNOG00000008508	RatGTEx
UniProt	A0A8I6A9C9	ENTREZGENE, UniProtKB/TrEMBL
	A6KRN3	ENTREZGENE, UniProtKB/TrEMBL
	F7FIQ9	ENTREZGENE, UniProtKB/TrEMBL
	Q9WUY6	ENTREZGENE
UniProt Secondary	Q9WUY6	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-12-06		acrosomal vesicle protein 1	Acrv1	sperm protein 10	Name updated	1299863	APPROVED
2004-09-10	Acrv1	sperm protein 10	Sp10		Symbol and Name updated	1299863	APPROVED
2002-08-07	Sp10	sperm protein 10			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar