Mgat1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) - Rat Genome Database

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Gene: Mgat1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase) Rattus norvegicus
Analyze
Symbol: Mgat1
Name: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
RGD ID: 620097
Description: Predicted to enable alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity and manganese ion binding activity. Predicted to be involved in protein N-linked glycosylation via asparagine. Predicted to act upstream of or within UDP-N-acetylglucosamine catabolic process and in utero embryonic development. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glcNAc-T I; GNT-I; mannoside acetylglucosaminyltransferase 1; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; MGAT1 gene for N-acetylglucosaminyltransferase; N-acetylglucosaminyltransferase I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81034,064,548 - 34,083,833 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1034,062,837 - 34,095,975 (+)EnsemblGRCr8
mRatBN7.21033,563,642 - 33,582,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1033,561,388 - 33,591,503 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1038,250,910 - 38,268,219 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0106,789,319 - 6,806,628 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01033,244,551 - 33,261,860 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01034,518,392 - 34,537,214 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1034,519,790 - 34,537,210 (+)Ensemblrn6Rnor6.0
Rnor_5.01034,294,712 - 34,313,531 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41034,706,908 - 34,724,328 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1032,944,950 - 32,962,376 (+)NCBICelera
RGSC_v3.11034,707,956 - 34,725,377 (+)NCBI
Cytogenetic Map10q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trimethylbenzene  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
clofibric acid  (EXP)
copper(II) chloride  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
flutamide  (EXP)
fulvestrant  (ISO)
hexadecanoic acid  (ISO)
hydralazine  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methylazoxymethanol  (ISO)
N-nitrosodiethylamine  (EXP)
nitrates  (ISO)
ozone  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
propiconazole  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
undecane  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cloning of a cDNA encoding N-acetylglucosaminyltransferase I from rat liver and analysis of its expression in rat tissues. Fukada T, etal., Biosci Biotechnol Biochem 1994 Jan;58(1):200-1.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:1421759   PMID:1702225   PMID:8290590   PMID:9781684   PMID:12878032   PMID:12913295   PMID:15489334   PMID:19199708   PMID:19946888   PMID:20378551   PMID:23376485   PMID:23533145  
PMID:24769233  


Genomics

Comparative Map Data
Mgat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81034,064,548 - 34,083,833 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1034,062,837 - 34,095,975 (+)EnsemblGRCr8
mRatBN7.21033,563,642 - 33,582,718 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1033,561,388 - 33,591,503 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1038,250,910 - 38,268,219 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0106,789,319 - 6,806,628 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01033,244,551 - 33,261,860 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01034,518,392 - 34,537,214 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1034,519,790 - 34,537,210 (+)Ensemblrn6Rnor6.0
Rnor_5.01034,294,712 - 34,313,531 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41034,706,908 - 34,724,328 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1032,944,950 - 32,962,376 (+)NCBICelera
RGSC_v3.11034,707,956 - 34,725,377 (+)NCBI
Cytogenetic Map10q21NCBI
MGAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385180,784,780 - 180,815,616 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5180,784,780 - 180,815,652 (-)Ensemblhg38GRCh38
GRCh375180,211,780 - 180,242,616 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365180,150,149 - 180,162,654 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345180,150,153 - 180,162,654NCBI
Celera5175,841,463 - 175,861,059 (-)NCBICelera
Cytogenetic Map5q35.3NCBI
HuRef5174,942,953 - 174,962,572 (-)NCBIHuRef
CHM1_15179,649,941 - 179,669,538 (-)NCBICHM1_1
T2T-CHM13v2.05181,341,132 - 181,371,969 (-)NCBIT2T-CHM13v2.0
Mgat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391149,135,018 - 49,153,854 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1149,135,018 - 49,153,857 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381149,244,191 - 49,263,027 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1149,244,191 - 49,263,030 (+)Ensemblmm10GRCm38
MGSCv371149,057,693 - 49,076,529 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361149,087,669 - 49,106,450 (+)NCBIMGSCv36mm8
Celera1153,806,759 - 53,825,547 (+)NCBICelera
Cytogenetic Map11B1.2NCBI
cM Map1129.27NCBI
Mgat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955530437,008 - 452,289 (+)Ensembl
ChiLan1.0NW_004955530436,518 - 452,296 (+)NCBIChiLan1.0ChiLan1.0
MGAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24175,799,001 - 175,824,176 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15173,963,080 - 173,988,256 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05175,978,425 - 176,003,620 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15183,292,153 - 183,317,334 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5183,293,237 - 183,294,574 (-)EnsemblpanPan2panpan1.1
MGAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.111114,587 - 129,014 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl11115,631 - 129,091 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha11172,388 - 187,101 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
Mgat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213118,240,717 - 118,260,848 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936826344,456 - 364,418 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936826344,452 - 364,929 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl257,900,216 - 57,920,954 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1257,849,185 - 57,920,410 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22159,732,009 - 159,753,282 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MGAT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12382,525,527 - 82,527,753 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2382,507,525 - 82,508,862 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
ChlSab1.1 Ensembl2382,507,525 - 82,508,862 (-)NCBIChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607513,929,392 - 13,950,488 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgat1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462481111,050,385 - 11,069,431 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462481111,050,378 - 11,069,734 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mgat1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1931,961,507 - 31,964,667 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mgat1
131 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:267
Count of miRNA genes:179
Interacting mature miRNAs:211
Transcripts:ENSRNOT00000052360
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103179628176796281Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102702353598502431Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)102744378772443787Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293679Bmd30Bone mineral density QTL 303.50.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102895035373950353Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102980091064653589Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102744378772443787Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2293652Bmd22Bone mineral density QTL 224.90.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)102744378772443787Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102702353561843633Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)102980091091417879Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
631530Tls3T-lymphoma susceptibility QTL 300.0001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)102758722696099902Rat
2289985Bp305Blood pressure QTL 305arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102907697874076978Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2293705Bmd25Bone mineral density QTL 257.10.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)102744378772443787Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102937704652699134Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103112911376129113Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102702353599451848Rat

Markers in Region
BF392858  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81034,070,095 - 34,070,331 (+)Marker Load Pipeline
mRatBN7.21033,568,978 - 33,569,215 (+)MAPPERmRatBN7.2
Rnor_6.01034,523,476 - 34,523,712NCBIRnor6.0
Rnor_5.01034,299,793 - 34,300,029UniSTSRnor5.0
RGSC_v3.41034,710,594 - 34,710,830UniSTSRGSC3.4
Celera1032,948,636 - 32,948,872UniSTS
RH 3.4 Map10367.9UniSTS
Cytogenetic Map10q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001439518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_030861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006246185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB012874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB012878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB100425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC133273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC074010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D16302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000052360   ⟹   ENSRNOP00000044560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,070,829 - 34,090,957 (+)Ensembl
mRatBN7.2 Ensembl1033,564,052 - 33,582,785 (+)Ensembl
Rnor_6.0 Ensembl1034,519,790 - 34,537,210 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000085832   ⟹   ENSRNOP00000068827
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1033,570,324 - 33,582,718 (+)Ensembl
Rnor_6.0 Ensembl1034,524,845 - 34,537,208 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093956   ⟹   ENSRNOP00000081587
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,071,013 - 34,090,957 (+)Ensembl
mRatBN7.2 Ensembl1033,569,718 - 33,591,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100116   ⟹   ENSRNOP00000083147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,079,394 - 34,090,409 (+)Ensembl
mRatBN7.2 Ensembl1033,566,948 - 33,591,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101283   ⟹   ENSRNOP00000081858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,065,021 - 34,095,975 (+)Ensembl
mRatBN7.2 Ensembl1033,563,912 - 33,591,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106126   ⟹   ENSRNOP00000090215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,064,999 - 34,092,289 (+)Ensembl
mRatBN7.2 Ensembl1033,561,388 - 33,591,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113892   ⟹   ENSRNOP00000079270
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,071,178 - 34,095,975 (+)Ensembl
mRatBN7.2 Ensembl1033,569,739 - 33,591,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116725   ⟹   ENSRNOP00000082878
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,075,928 - 34,088,458 (+)Ensembl
mRatBN7.2 Ensembl1033,574,796 - 33,591,503 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000127615   ⟹   ENSRNOP00000104664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,071,940 - 34,095,975 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156181   ⟹   ENSRNOP00000110059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,062,837 - 34,084,008 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000168274   ⟹   ENSRNOP00000110004
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1034,063,217 - 34,084,008 (+)Ensembl
RefSeq Acc Id: NM_030861   ⟹   NP_110488
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,066,409 - 34,083,829 (+)NCBI
mRatBN7.21033,565,293 - 33,582,714 (+)NCBI
Rnor_6.01034,519,790 - 34,537,210 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
RGSC_v3.41034,706,908 - 34,724,328 (+)RGD
Celera1032,944,950 - 32,962,376 (+)RGD
Sequence:
RefSeq Acc Id: XM_006246182   ⟹   XP_006246244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,983 - 34,083,833 (+)NCBI
mRatBN7.21033,563,867 - 33,582,718 (+)NCBI
Rnor_6.01034,518,392 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246183   ⟹   XP_006246245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,983 - 34,083,833 (+)NCBI
mRatBN7.21033,569,786 - 33,582,718 (+)NCBI
Rnor_6.01034,524,220 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246184   ⟹   XP_006246246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,983 - 34,083,833 (+)NCBI
mRatBN7.21033,569,785 - 33,582,718 (+)NCBI
Rnor_6.01034,524,220 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246185   ⟹   XP_006246247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,983 - 34,083,833 (+)NCBI
mRatBN7.21033,563,867 - 33,582,718 (+)NCBI
Rnor_6.01034,518,392 - 34,537,214 (+)NCBI
Rnor_5.01034,294,712 - 34,313,531 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063269936   ⟹   XP_063126006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,597 - 34,083,833 (+)NCBI
RefSeq Acc Id: XM_063269937   ⟹   XP_063126007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,065,196 - 34,083,833 (+)NCBI
RefSeq Acc Id: XM_063269938   ⟹   XP_063126008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,548 - 34,083,833 (+)NCBI
RefSeq Acc Id: XM_063269939   ⟹   XP_063126009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,597 - 34,083,833 (+)NCBI
RefSeq Acc Id: XM_063269940   ⟹   XP_063126010
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81034,064,563 - 34,083,833 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001426447 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426457 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426458 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426459 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426460 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426461 (Get FASTA)   NCBI Sequence Viewer  
  NP_001426462 (Get FASTA)   NCBI Sequence Viewer  
  NP_110488 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246244 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246245 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246246 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246247 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126006 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126007 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126008 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126009 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126010 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH74010 (Get FASTA)   NCBI Sequence Viewer  
  BAA03807 (Get FASTA)   NCBI Sequence Viewer  
  EDM04213 (Get FASTA)   NCBI Sequence Viewer  
  EDM04214 (Get FASTA)   NCBI Sequence Viewer  
  EDM04215 (Get FASTA)   NCBI Sequence Viewer  
  EDM04216 (Get FASTA)   NCBI Sequence Viewer  
  EDM04217 (Get FASTA)   NCBI Sequence Viewer  
  EDM04218 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044560.1
  ENSRNOP00000079270.1
  ENSRNOP00000081587.1
  ENSRNOP00000081858
  ENSRNOP00000081858.1
  ENSRNOP00000082878.1
  ENSRNOP00000083147
  ENSRNOP00000083147.1
  ENSRNOP00000090215
  ENSRNOP00000090215.1
  ENSRNOP00000110004
  ENSRNOP00000110059
GenBank Protein Q09325 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_110488   ⟸   NM_030861
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot),   A6HDW1 (UniProtKB/TrEMBL),   A0A8L2R007 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246247   ⟸   XM_006246185
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006246244   ⟸   XM_006246182
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006246246   ⟸   XM_006246184
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot),   A6HDW1 (UniProtKB/TrEMBL),   A0A8L2R007 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246245   ⟸   XM_006246183
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot),   A6HDW1 (UniProtKB/TrEMBL),   A0A8L2R007 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068827   ⟸   ENSRNOT00000085832
Ensembl Acc Id: ENSRNOP00000044560   ⟸   ENSRNOT00000052360
Ensembl Acc Id: ENSRNOP00000090215   ⟸   ENSRNOT00000106126
Ensembl Acc Id: ENSRNOP00000083147   ⟸   ENSRNOT00000100116
Ensembl Acc Id: ENSRNOP00000082878   ⟸   ENSRNOT00000116725
Ensembl Acc Id: ENSRNOP00000079270   ⟸   ENSRNOT00000113892
Ensembl Acc Id: ENSRNOP00000081858   ⟸   ENSRNOT00000101283
Ensembl Acc Id: ENSRNOP00000081587   ⟸   ENSRNOT00000093956
RefSeq Acc Id: XP_063126008   ⟸   XM_063269938
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126010   ⟸   XM_063269940
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126006   ⟸   XM_063269936
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot),   A6HDW1 (UniProtKB/TrEMBL),   A0A8L2R007 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126009   ⟸   XM_063269939
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126007   ⟸   XM_063269937
- Peptide Label: isoform X1
- UniProtKB: Q09325 (UniProtKB/Swiss-Prot),   A6HDW1 (UniProtKB/TrEMBL),   A0A8L2R007 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000110004   ⟸   ENSRNOT00000168274
Ensembl Acc Id: ENSRNOP00000110059   ⟸   ENSRNOT00000156181
Ensembl Acc Id: ENSRNOP00000104664   ⟸   ENSRNOT00000127615

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q09325-F1-model_v2 AlphaFold Q09325 1-447 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697156
Promoter ID:EPDNEW_R7664
Type:initiation region
Name:Mgat1_1
Description:mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01034,524,837 - 34,524,897EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620097 AgrOrtholog
BioCyc Gene G2FUF-25299 BioCyc
BioCyc Pathway PWY-7426 [complex N-linked glycan biosynthesis (vertebrates)] BioCyc
BioCyc Pathway Image PWY-7426 BioCyc
Ensembl Genes ENSRNOG00000031208 Ensembl
  ENSRNOG00000068826 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000052360.2 UniProtKB/Swiss-Prot
  ENSRNOT00000093956.1 UniProtKB/Swiss-Prot
  ENSRNOT00000100116 ENTREZGENE
  ENSRNOT00000100116.1 UniProtKB/Swiss-Prot
  ENSRNOT00000101283 ENTREZGENE
  ENSRNOT00000101283.1 UniProtKB/Swiss-Prot
  ENSRNOT00000106126 ENTREZGENE
  ENSRNOT00000106126.1 UniProtKB/Swiss-Prot
  ENSRNOT00000113892.1 UniProtKB/Swiss-Prot
  ENSRNOT00000116725.1 UniProtKB/Swiss-Prot
  ENSRNOT00000156181 ENTREZGENE
  ENSRNOT00000168274 ENTREZGENE
Gene3D-CATH N-Acetylglucosaminyltransferase I, Domain 2 UniProtKB/Swiss-Prot
  Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7100030 IMAGE-MGC_LOAD
InterPro Glyco_trans_13 UniProtKB/Swiss-Prot
  Glycosyltransferase_13 UniProtKB/Swiss-Prot
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot
KEGG Report rno:81519 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91661 IMAGE-MGC_LOAD
NCBI Gene 81519 ENTREZGENE
PANTHER ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE UniProtKB/Swiss-Prot
  PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE UniProtKB/Swiss-Prot
Pfam GNT-I UniProtKB/Swiss-Prot
PhenoGen Mgat1 PhenoGen
RatGTEx ENSRNOG00000031208 RatGTEx
  ENSRNOG00000068826 RatGTEx
Superfamily-SCOP SSF53448 UniProtKB/Swiss-Prot
UniProt A0A8L2R007 ENTREZGENE
  A6HDW1 ENTREZGENE, UniProtKB/TrEMBL
  MGAT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-13 Mgat1  alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase  Mgat1  mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-08-29 Mgat1  mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase  Mgat1  mannoside acetylglucosaminyltransferase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Mgat1  mannoside acetylglucosaminyltransferase 1    Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase  Name updated 1299863 APPROVED
2005-01-20 Mgat1  Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase    N-acetylglucosaminyltransferase I  Name updated 1299863 APPROVED
2002-08-07 Mgat1  N-acetylglucosaminyltransferase I      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 729009