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Gene: Capn5 (calpain 5) Rattus norvegicus

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Symbol:

Capn5

Name:

calpain 5

RGD ID:

620084

Description:

Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Involved in granulosa cell differentiation; luteinization; and ovarian follicle development. Predicted to be located in cell surface and synapse. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in neovascular inflammatory vitreoretinopathy. Orthologous to human CAPN5 (calpain 5); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

calpain-5; high-temperature requirement factor A3; Htra3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CAPN5 (calpain 5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Capn5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Capn5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CAPN5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CAPN5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Capn5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CAPN5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CAPN5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Capn5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Capn5 (calpain 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KRTAP16-1 (keratin associated protein 16-1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	CAPN5 (calpain 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Capn5 (calpain 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	capn5a (calpain 5a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	capn5a (calpain 5a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	capn5b (calpain 5b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	capn5b (calpain 5b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	tra-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	capn5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	capn5	Alliance	DIOPT (OMA\|OrthoFinder)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	161,827,474 - 161,884,142 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	161,827,474 - 161,884,142 (-)	Ensembl				GRCr8
mRatBN7.2	1	152,416,252 - 152,472,923 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	152,416,252 - 152,472,923 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	160,403,310 - 160,459,975 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	167,583,490 - 167,640,155 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	160,457,009 - 160,513,680 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	163,073,134 - 163,129,736 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	163,073,124 - 163,129,641 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	169,278,330 - 169,336,574 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	155,366,678 - 155,421,183 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	150,507,123 - 150,563,735 (-)	NCBI		Celera
RGSC_v3.1	1	155,445,083 - 155,499,584 (-)	NCBI
Cytogenetic Map	1	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cone-rod dystrophy (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

neovascular inflammatory vitreoretinopathy (ISO)

occult macular dystrophy (ISO)

retinitis pigmentosa 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

beta-lapachone (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

cisplatin (ISO)

clothianidin (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

DDE (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

fipronil (EXP)

flavonoids (EXP)

folic acid (ISO)

genistein (ISO)

hypochlorous acid (ISO)

iron dichloride (ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

methidathion (ISO)

mifepristone (ISO)

N-methyl-4-phenylpyridinium (EXP)

nickel atom (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (ISO)

phenytoin (ISO)

pirinixic acid (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

granulosa cell differentiation (IEP)

luteinization (IEP)

ovarian follicle development (IEP)

proteolysis (IBA,IEA)

sensory perception of smell (IEA)

signal transduction (IEA)

Cellular Component

cell surface (IEA,ISO,ISS)

cytoplasm (IBA)

synapse (IEA,ISO)

Molecular Function

calcium-dependent cysteine-type endopeptidase activity (IBA,IEA)

cysteine-type peptidase activity (IEA)

hydrolase activity (IEA)

peptidase activity (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Evolutionary conservation of mammalian HTRA3 and its developmental regulation in the rat ovary.	Bowden M, etal., J Exp Zoolog B Mol Dev Evol. 2009 May 4.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Molecular cloning and characterization of rat and human calpain-5.	Waghray A, etal., Biochem Biophys Res Commun 2004 Nov 5;324(1):46-51.

Additional References at PubMed

PMID:19056867	PMID:21423176	PMID:23055945	PMID:23376485	PMID:23533145	PMID:24838245	PMID:27152965

Genomics

Comparative Map Data

Capn5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	161,827,474 - 161,884,142 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	161,827,474 - 161,884,142 (-)	Ensembl				GRCr8
mRatBN7.2	1	152,416,252 - 152,472,923 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	152,416,252 - 152,472,923 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	160,403,310 - 160,459,975 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	167,583,490 - 167,640,155 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	160,457,009 - 160,513,680 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	163,073,134 - 163,129,736 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	163,073,124 - 163,129,641 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	169,278,330 - 169,336,574 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	155,366,678 - 155,421,183 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	150,507,123 - 150,563,735 (-)	NCBI		Celera
RGSC_v3.1	1	155,445,083 - 155,499,584 (-)	NCBI
Cytogenetic Map	1	q32	NCBI

CAPN5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	77,066,971 - 77,126,155 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	77,066,961 - 77,126,155 (+)	Ensembl			hg38	GRCh38
GRCh37	11	76,778,018 - 76,837,201 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	76,455,640 - 76,514,849 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	11	76,455,658 - 76,514,844	NCBI
Celera	11	74,085,463 - 74,144,685 (+)	NCBI		Celera
Cytogenetic Map	11	q13.5	NCBI
HuRef	11	73,075,693 - 73,134,573 (+)	NCBI		HuRef
CHM1_1	11	76,661,081 - 76,720,452 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	76,997,312 - 77,056,732 (+)	NCBI		T2T-CHM13v2.0

Capn5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	97,770,766 - 97,828,148 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	97,770,766 - 97,827,481 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	98,121,559 - 98,178,946 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	98,121,559 - 98,178,274 (-)	Ensembl			mm10	GRCm38
MGSCv37	7	105,270,075 - 105,326,703 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	97,996,757 - 98,053,385 (-)	NCBI		MGSCv36	mm8
Celera	7	98,442,279 - 98,499,525 (-)	NCBI		Celera
Cytogenetic Map	7	E1	NCBI
cM Map	7	53.57	NCBI

Capn5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	14,651,207 - 14,706,887 (-)	Ensembl
ChiLan1.0	NW_004955414	14,652,578 - 14,706,833 (-)	NCBI	ChiLan1.0	ChiLan1.0

CAPN5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	77,986,781 - 78,043,703 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	79,034,987 - 79,091,265 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	72,118,036 - 72,174,920 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	75,778,879 - 75,817,832 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	75,778,879 - 75,817,827 (+)	Ensembl			panPan2	panpan1.1

CAPN5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	21,626,090 - 21,678,545 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	21,627,791 - 21,678,880 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	21,453,573 - 21,506,018 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	21,825,703 - 21,878,142 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	21,825,714 - 21,876,967 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	21,601,212 - 21,653,579 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	21,817,385 - 21,869,821 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	21,741,079 - 21,793,561 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Capn5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	64,093,284 - 64,148,772 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936498	5,692,867 - 5,748,416 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936498	5,692,910 - 5,747,329 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAPN5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	11,207,636 - 11,246,711 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	9	11,194,302 - 11,246,713 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	12,288,762 - 12,341,062 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAPN5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	68,276,310 - 68,334,254 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	68,293,739 - 68,334,250 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666043	57,441,383 - 57,499,094 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Capn5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624863	148,889 - 202,952 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624863	148,941 - 202,853 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Capn5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	96,406,687 - 96,461,594 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Capn5
1385 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	319
Count of miRNA genes:	193
Interacting mature miRNAs:	240
Transcripts:	ENSRNOT00000019370
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	131179947	176179947	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	153679879	198679879	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
631684	Bp117	Blood pressure QTL 117	8.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	120082258	165082258	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	153679879	205813246	Rat
8694166	Bw147	Body weight QTL 147	6.83	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	1	153788989	198788989	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	160573753	210707719	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	160573753	210707719	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	161077990	206077990	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	159894717	207261263	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	141173126	169168317	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	155359438	194575574	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	131243790	176243790	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	129182274	174182274	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	153680016	182383862	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	153680016	183564652	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	128019551	173019551	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	178317588	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	210707719	Rat
8693608	Alc24	Alcohol consumption QTL 24	2.3	0.74	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	1	159863716	177663210	Rat
1576310	Schws2	Schwannoma susceptibility QTL 2		0.029	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	1	153788989	198788989	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
7411599	Foco11	Food consumption QTL 11	18.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	1	153788989	198788989	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	210707719	Rat

Markers in Region

D1Mgh19

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	152,441,635 - 152,441,834 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	163,098,517 - 163,098,713	NCBI	Rnor6.0
Rnor_5.0	1	169,303,713 - 169,303,909	UniSTS	Rnor5.0
RGSC_v3.4	1	155,389,992 - 155,390,189	RGD	RGSC3.4
RGSC_v3.4	1	155,389,993 - 155,390,189	UniSTS	RGSC3.4
Celera	1	150,532,491 - 150,532,687	UniSTS
RGSC_v3.1	1	155,468,398 - 155,468,595	RGD
RH 3.4 Map	1	1166.1	RGD
RH 3.4 Map	1	1166.1	UniSTS
RH 2.0 Map	1	777.9	RGD
SHRSP x BN Map	1	68.3	RGD
Cytogenetic Map	1	q32	UniSTS

D1Hmgc9

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	152,438,505 - 152,438,682 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	163,095,387 - 163,095,563	NCBI	Rnor6.0
Rnor_5.0	1	169,300,583 - 169,300,759	UniSTS	Rnor5.0
RGSC_v3.4	1	155,386,863 - 155,387,039	UniSTS	RGSC3.4
Celera	1	150,529,361 - 150,529,537	UniSTS
RH 3.4 Map	1	1171.8	RGD
RH 3.4 Map	1	1171.8	UniSTS
Cytogenetic Map	1	q32	UniSTS

RH136948

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	152,416,290 - 152,416,441 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	163,073,173 - 163,073,323	NCBI	Rnor6.0
Rnor_5.0	1	169,278,369 - 169,278,519	UniSTS	Rnor5.0
RGSC_v3.4	1	155,364,724 - 155,364,874	UniSTS	RGSC3.4
Celera	1	150,507,162 - 150,507,312	UniSTS
RH 3.4 Map	1	1166.1	UniSTS
Cytogenetic Map	1	q32	UniSTS

BI280088

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	152,416,862 - 152,417,037 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	163,073,745 - 163,073,919	NCBI	Rnor6.0
Rnor_5.0	1	169,278,941 - 169,279,115	UniSTS	Rnor5.0
RGSC_v3.4	1	155,365,296 - 155,365,470	UniSTS	RGSC3.4
Celera	1	150,507,734 - 150,507,908	UniSTS
RH 3.4 Map	1	1166.1	UniSTS
Cytogenetic Map	1	q32	UniSTS

Omp

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	152,440,407 - 152,440,523 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	163,097,289 - 163,097,404	NCBI	Rnor6.0
Rnor_5.0	1	169,302,485 - 169,302,600	UniSTS	Rnor5.0
RGSC_v3.4	1	155,388,765 - 155,388,880	UniSTS	RGSC3.4
Celera	1	150,531,263 - 150,531,378	UniSTS
Cytogenetic Map	1	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	161	91	90	59	92	59	6	356	192	11	140	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_134461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229731	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008759673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277369	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131619	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF484958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019370 ⟹ ENSRNOP00000019370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	161,827,474 - 161,871,638 (-)	Ensembl
mRatBN7.2 Ensembl	1	152,416,252 - 152,460,419 (-)	Ensembl
Rnor_6.0 Ensembl	1	163,073,124 - 163,117,235 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000083055 ⟹ ENSRNOP00000070614

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	161,827,474 - 161,884,142 (-)	Ensembl
mRatBN7.2 Ensembl	1	152,416,252 - 152,472,923 (-)	Ensembl
Rnor_6.0 Ensembl	1	163,075,127 - 163,129,641 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000141273 ⟹ ENSRNOP00000107706

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	161,850,498 - 161,884,142 (-)	Ensembl

RefSeq Acc Id:

NM_134461 ⟹ NP_604456

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	161,827,474 - 161,884,142 (-)	NCBI
mRatBN7.2	1	152,416,252 - 152,472,923 (-)	NCBI
Rnor_6.0	1	163,073,134 - 163,129,736 (-)	NCBI
Rnor_5.0	1	169,278,330 - 169,336,574 (-)	NCBI
RGSC_v3.4	1	155,366,678 - 155,421,183 (-)	RGD
Celera	1	150,507,123 - 150,563,735 (-)	NCBI

Sequence:

show sequence

ACAGACCGAAGCCCCGGGGTCCAAGTTCCCGCCCCTGCCTGCGGGCTGCCGGGGCAGCGTTTCC
CCGCAGAGTCCCAGGCTGTGGCGCGGGCAGATCCAACCTCCGCTCCAGTGCCCGCACCGTGCCC
TGCATCTCAGGAGTCCGGCTCCAGCTGCGGCGACGCGGCAGGGGCCTCCCCTAATTGGGGACGT
GGTCACCATGTTCTCCTGCACAAAGGCCTATGAAGACCAGAATTACTCAGCTCTGAAGCGGGCC
TGTCTGCGCAGGAAGGTGCTGTTCGAGGACCCCCACTTCCCTGCCACCGACGACTCACTCTACT
ATAAGGGTACCCCAGGGCCCACAGTCAGGTGGAAGCGGCCTAAGGATATCTGCGATGATCCCCG
GCTCTTCGTCGATGGCATCAGCTCGCATGACCTGCACCAGGGCCAGGTGGGCAACTGCTGGTTT
GTGGCCGCCTGCTCATCACTCGCCTCCCGGGAGTCACTCTGGCAAAAGGTCATCCCAGACTGGA
AGGAGCAGGAATGGAACCCCGAGAAGCCCGACAGCTATGCTGGCATCTTCCATTTCAACTTCTG
GCGCTTTGGGGAGTGGGTGGACGTGGTCGTCGATGACCGGCTGCCCACAGTCAACAACCAACTC
ATTTACTGCCACTCCAACTCGAAAAATGAGTTCTGGTGTGCCCTGGTGGAGAAGGCCTATGCCA
AGCTGGCAGGCTGTTACCAGGCCCTGGACGGAGGCAACACAGCCGATGCACTGGTGGATTTCAC
AGGCGGTGTTTCGGAACCCATCGACCTGACCGAGGGGGACTTGGCCACAGATGAGGCTAAGAGA
AGCCAGCTCTTTGAACGTGTGTTGAAGGTGCACAGCAGAGGTGGGCTCATCAGTGCCTCCATCA
AGGCTATGACAGCAGCTGACATGGAGACCCGTCTGGCCTGTGGTCTGGTGAAGGGCCATGCATA
TGCTGTCACCGATGTGCGCAAGGTGCGCCTGGGCCATGGCCTGCTGGCCTTCTTCAAGTCAGAG
AAGCTGGACATGATCCGTCTGAGGAACCCCTGGGGCGAGCGGGAGTGGACCGGGCCCTGGAGTG
ACACGTCAGAGGAATGGCAGAAAGTGAGCAAGAGTGAGAGGGAGAAAATGGGCGTGACCGTACA
GGACGATGGTGAATTCTGGATGACCTTTGAGGACATGTGCCGATACTTCACCGACATCATTAAG
TGCCGCCTGATTAATACGTCCTACCTGAGCATCCACAAGACATGGGAGGAGGCCCGGCTGCGTG
GTGCCTGGACGAGACATGAGGACCCCCAGCAGAACCGCAGTGGAGGCTGCATCAACCACAAGGA
CACTTTCTTCCAGAACCCACAGTACATATTTGAAGTCAAGAAGCCAGAAGATGAAGTGCTGATC
TGCATCCAGCAGCGGCCCAAACGCTCGACTCGCCGAGAGGGCAAAGGGGAGAATCTGGCCATCG
GCTTCGACATCTATAAGGTGGAAGAGAACCGCCAGTACCGGATGCACAGCCTGCAGCATAAGGC
CGCCAGCTCCATCTACATCAATTCTCGGAGTGTTTTCCTGCGGACAGAGCTGCCTGAGGGCCGC
TACGTCATCATCCCTACCACCTTTGAGCCAGGCCACACTGGCGAGTTCCTGCTCCGCGTCTTCA
CAGACGTTCCCTCCAACTGCCGGGAGCTACGCCTGGATGAGCCCCCTCGTACCTGCTGGAGCTC
CCTGTGTGGCTACCCTCAGCAGGTGACCCAGGTCCATGTCCTGGGAGCTGCTGGCCTCAAGGAC
TCTTCCACAGGAGCAAACTCATATGTGATCATCAAGTGTGAGGGTGAAAAGGTTCGCTCAGCTG
TGCAGAGAGGGACCTCGACGCCAGAGTACAATGTGAAAGGCATCTTCTATCGCAAGAAACTGTC
TCAGCCCATCACTGTGCAGGTCTGGAATCACCGAGTCCTGAAGGATGAATTCCTGGGCCAGGTG
CACCTGAAGACTGCCCCGGATGACCTGCAGGACCTGCACAGCCTCCATCTCCAGGACCGCAGTG
GCCGGCAGCCCAGCGACTTGCCAGGCATCGTCGCTGTGCGTGTCCTCTGCAGTGCCTCTCTCAC
GGCTGTCTGATGCCAGCCAGCCTGCCCAGCCCCACTAGTTCTCAGCACTACTCGCATGTCCCCA
CCTGGCCTGGGACCAGCCTGGGAACCAGACACTGGGCCCTTTGCCCGCTCTTCCACTGACCCAC
TGTGTGACCGAGGAGAGCCCTGCCCCTCTCTGAGCCTCAGTGTTTGGAGGGCCCCGAAGAATTC
CCCTCTCGTGGGGGAGTTTTCTTGCCTAAGATTTAAAGCGGCTCCTTCTACCCAGTGGGCACTG
CCGTCAAGGGGCTATCTGTTGAAAATGTTTCCCCTGGCCCTGCTATCTGCAGAGGAGTGCCAAG
ACGTCAATTGTTTACACACAAACTGCCATGTCCCAAGTCCCTTCCCTCTCCTCGTTTGCTGTGG
GGGAGGTTGCTTCCCTCCCCAGATCTTTGCTGCGTAGCTTAGAGTGACCTTAAACTTCTGATCC
CCCTGCCTCCACCTCCTCAGGTGGAACCCAGGGCTTTGTGCATGCTAGGCGAGCGCTTACCAAC
TGAGCTGCACACCCAATCCCACTACACATCATTTTAAAACCATCTTGAAAGAACCCTTAGCAGG
CATACGCAGGACGCCCCACCTCCATCCATTTAATTGCTCTATCGACTTGCCCTGTTAGCCGCCC
CGGGCTTGCTGATTCTCAGGTCTTCTTGGAGATAGATACCTTCCTGAGACCAGGCTCTGACTTC
ACTCTCAGCCCCTGAAGAGCTATGGTCATGCTGGTGATTTCCCAACACTCTACTTGTGATGTTG
GACCAAGTGGCCCGGGCCAGGCTGATGTAAGGCTATGGGAGACCCAAGGGGGACACATGGTGCC
TCTGCTGAAGGACCCTGGGGTTTTCTTGGAAGAAAAGACTGTAGGATGGATGTACTAGGCCTTC
AGGGCTAGTTCATCTGTTGGGTGTCACAGACAGGGACCAGAGGGCTTTCCACCAGCATACCCCA
AAGATCTAAGGAAGCCACCACACTCTTACTGTCCGTACAGACCAAAATGTTACTCTCAGTCCTC
AGCATTTGATAGTCTTAGCATTTAAAACAATCTCGGTGTAAAGGGAAGTCGGCCCCCACATTTG
TTCTTTTCAAACTCGTTTTGTTGGGCTTCTGCTTTTATCTTGACATTGAACATGAGAGGGCACG
GTCACAGTGGGACCTTCTCAGAGGAGTCTCAGAGAATGATGGAGGCGAGATGTTCCTTCCTGGC
TGCCGTCTGCGTTCTGTCTCTGGTCCCTCCTACATGGTCCTATTCCTGGCTGGAGGTGCTGGAT
TCTGACTGCCATCTTGCTCCATGGTGGCTCTTCTGGCCTGGGACCATTGTCCACAGTAAGGGCT
AGGAGCTGAACTGAAAGGATGAGAGGATTCCTCCTGCACAGTCAGGGCTTCCCTTCAATGACCT
GGGCCTGGGATTGTGCATCCCACCAGGAGCAAGTCACTTCAACCTCCCGTGCCTCGATTCCTCC
CTCTTGTAGCATGGCGCTGGCCTCTCCTGTTGTGAGGACTCTTAAAAGAATAAGAGCAAGGCCA
CACCACTTCCACTGTGTGTCTCTCTATTGTATACTCTGCACGGTCACATGATCCCTCCACTTCT
CAACGGCTGTCGCAAATGAAGACTGCAGTCAGGAAGCGGGGATGAGCACCTGCCTCACGATCTT
GGCTCTCAGGGCCTGGCGTGTGGGTCTCAGCTCAGCCATATCCCTCTGAGGCACAGGGCAAACG
AGGACCAAGTAGCAGACTGCAGATGCTTCACCTGGCATCTAGACACTGCCCCCCGCCCCCCACC
TCCAGCAGAACTGGGCCAGCAGCTCTGTTCTTGCTTCCTCTCTCTTAAGCTAGGCCAGGCTGGC
TCCTGGCTGTGAAGGAACCTCTGGTCCCTAGGAAACCCTGAAGACTAGACAGGTGGGGACAGGG
TAGAGCAGGGACAGCAGTGGCTTTGTTCACCATTTGCACCCAGGAGGCCTTGTAGTGTTACAGT
TGCAGTCATCAGCCCTATGATGTACACTACATGGACCAGCAGGACCTGGCCTTCACTCCTCCAG
GCTACTATGCCCTGGGGTCAAGGGAGAGGAACTCTGTTATCTTCTCAGAATAAATATTACTGCC
ACTCTAGAGGGA

hide sequence

RefSeq Acc Id:

XM_063277344 ⟹ XP_063133414

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	161,827,474 - 161,873,936 (-)	NCBI

RefSeq Acc Id:

XM_063277369 ⟹ XP_063133439

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	161,827,474 - 161,869,416 (-)	NCBI

RefSeq Acc Id:

XM_063277401 ⟹ XP_063133471

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	161,827,474 - 161,869,049 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_604456	(Get FASTA)	NCBI Sequence Viewer
	XP_063133414	(Get FASTA)	NCBI Sequence Viewer
	XP_063133439	(Get FASTA)	NCBI Sequence Viewer
	XP_063133471	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAL92024	(Get FASTA)	NCBI Sequence Viewer
	EDM18452	(Get FASTA)	NCBI Sequence Viewer
	EDM18453	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019370
	ENSRNOP00000070614
GenBank Protein	Q8R4C0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_604456 ⟸ NM_134461

- UniProtKB:

Q8R4C0 (UniProtKB/Swiss-Prot), A0A0G2JYD8 (UniProtKB/TrEMBL), A6I6C6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFSCTKAYEDQNYSALKRACLRRKVLFEDPHFPATDDSLYYKGTPGPTVRWKRPKDICDDPRLF
VDGISSHDLHQGQVGNCWFVAACSSLASRESLWQKVIPDWKEQEWNPEKPDSYAGIFHFNFWRF
GEWVDVVVDDRLPTVNNQLIYCHSNSKNEFWCALVEKAYAKLAGCYQALDGGNTADALVDFTGG
VSEPIDLTEGDLATDEAKRSQLFERVLKVHSRGGLISASIKAMTAADMETRLACGLVKGHAYAV
TDVRKVRLGHGLLAFFKSEKLDMIRLRNPWGEREWTGPWSDTSEEWQKVSKSEREKMGVTVQDD
GEFWMTFEDMCRYFTDIIKCRLINTSYLSIHKTWEEARLRGAWTRHEDPQQNRSGGCINHKDTF
FQNPQYIFEVKKPEDEVLICIQQRPKRSTRREGKGENLAIGFDIYKVEENRQYRMHSLQHKAAS
SIYINSRSVFLRTELPEGRYVIIPTTFEPGHTGEFLLRVFTDVPSNCRELRLDEPPRTCWSSLC
GYPQQVTQVHVLGAAGLKDSSTGANSYVIIKCEGEKVRSAVQRGTSTPEYNVKGIFYRKKLSQP
ITVQVWNHRVLKDEFLGQVHLKTAPDDLQDLHSLHLQDRSGRQPSDLPGIVAVRVLCSASLTAV

hide sequence

Ensembl Acc Id:

ENSRNOP00000070614 ⟸ ENSRNOT00000083055

Ensembl Acc Id:

ENSRNOP00000019370 ⟸ ENSRNOT00000019370

RefSeq Acc Id:	XP_063133414 ⟸ XM_063277344
- Peptide Label:	isoform X1
- UniProtKB:	Q8R4C0 (UniProtKB/Swiss-Prot), G3V7U6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133439 ⟸ XM_063277369
- Peptide Label:	isoform X2
- UniProtKB:	Q8R4C0 (UniProtKB/Swiss-Prot), A0A0G2JYD8 (UniProtKB/TrEMBL), A6I6C6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133471 ⟸ XM_063277401
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000107706 ⟸ ENSRNOT00000141273

Protein Domains

C2 Calpain catalytic

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8R4C0-F1-model_v2	AlphaFold	Q8R4C0	1-640	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690217

Promoter ID:

EPDNEW_R742

Type:

initiation region

Name:

Capn5_1

Description:

calpain 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	163,129,713 - 163,129,773	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620084	AgrOrtholog
BioCyc Gene	G2FUF-58429	BioCyc
Ensembl Genes	ENSRNOG00000014251	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000019370	ENTREZGENE
	ENSRNOT00000083055	ENTREZGENE
Gene3D-CATH	2.60.120.380	UniProtKB/Swiss-Prot
	2.60.40.150	UniProtKB/Swiss-Prot
	Cysteine proteinases	UniProtKB/Swiss-Prot
InterPro	C2_Calpain	UniProtKB/Swiss-Prot
	C2_dom	UniProtKB/Swiss-Prot
	C2_domain_sf	UniProtKB/Swiss-Prot
	C2_III	UniProtKB/Swiss-Prot
	Calpain_cysteine_protease	UniProtKB/Swiss-Prot
	Calpain_domain_III	UniProtKB/Swiss-Prot
	Calpain_III	UniProtKB/Swiss-Prot
	Calpain_III_sf	UniProtKB/Swiss-Prot
	Papain-like_cys_pep_sf	UniProtKB/Swiss-Prot
	Pept_cys_AS	UniProtKB/Swiss-Prot
	Peptidase_C2_calpain_cat	UniProtKB/Swiss-Prot
NCBI Gene	171495	ENTREZGENE
PANTHER	CALPAIN	UniProtKB/Swiss-Prot
	CALPAIN-5	UniProtKB/Swiss-Prot
Pfam	Calpain_III	UniProtKB/Swiss-Prot
	Peptidase_C2	UniProtKB/Swiss-Prot
	PF00168	UniProtKB/Swiss-Prot
PhenoGen	Capn5	PhenoGen
PRINTS	CALPAIN	UniProtKB/Swiss-Prot
PROSITE	CALPAIN_CAT	UniProtKB/Swiss-Prot
	PS50004	UniProtKB/Swiss-Prot
	THIOL_PROTEASE_CYS	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000014251	RatGTEx
SMART	calpain_III	UniProtKB/Swiss-Prot
	CysPc	UniProtKB/Swiss-Prot
	SM00239	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF49562	UniProtKB/Swiss-Prot
	SSF49758	UniProtKB/Swiss-Prot
	SSF54001	UniProtKB/Swiss-Prot
UniProt	A0A0G2JYD8	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LZT6_RAT	UniProtKB/TrEMBL
	A6I6C6	ENTREZGENE, UniProtKB/TrEMBL
	CAN5_RAT	UniProtKB/Swiss-Prot
	G3V7U6	ENTREZGENE, UniProtKB/TrEMBL
	Q8R4C0	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-09-10	Capn5	calpain 5			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Capn5	calpain 5			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

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