Septin2 (septin 2) - Rat Genome Database

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Gene: Septin2 (septin 2) Rattus norvegicus
Analyze
Symbol: Septin2
Name: septin 2
RGD ID: 620056
Description: Predicted to enable several functions, including GTPase activity; enzyme regulator activity; and identical protein binding activity. Involved in neuron projection development. Located in perinuclear region of cytoplasm. Part of exocyst. Is active in presynapse. Orthologous to human SEPTIN2 (septin 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC93254; Nedd5; Sept2; septin-2; vascular endothelial cell specific protein 11; Vesp11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,465,535 - 101,498,766 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9101,465,650 - 101,498,759 (+)EnsemblGRCr8
mRatBN7.2994,018,141 - 94,051,386 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl994,018,208 - 94,051,386 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9102,453,742 - 102,486,891 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,589,577 - 107,622,561 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,945,723 - 105,978,707 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,624,876 - 100,658,053 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,624,876 - 100,658,050 (+)Ensemblrn6Rnor6.0
Rnor_5.09100,277,885 - 100,311,082 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4992,756,091 - 92,789,257 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera991,552,840 - 91,585,967 (+)NCBICelera
RGSC_v3.1992,960,859 - 92,994,023 (+)NCBI
Cytogenetic Map9q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axoneme  (IEA,ISO)
cell cortex  (IEA)
cell division site  (IBA)
cell projection  (IEA,ISO)
cell surface  (IEA,ISO)
ciliary membrane  (IEA,ISO,ISS)
ciliary transition zone  (IEA,ISO)
cilium  (IEA,ISO)
cleavage furrow  (IEA)
cytoplasm  (IEA,ISO)
cytoskeleton  (IEA)
exocyst  (IDA)
intercellular bridge  (IEA,ISO)
microtubule cytoskeleton  (IBA,IEA,ISO)
midbody  (IEA)
motile cilium  (IEA)
non-motile cilium  (IEA,ISO)
nucleus  (IEA,ISO)
perinuclear region of cytoplasm  (IDA)
photoreceptor connecting cilium  (IEA,ISO)
plasma membrane  (IEA,ISO)
presynapse  (IDA,IEP)
septin complex  (IBA,IEA,ISO)
septin ring  (IBA)
sperm annulus  (IEA,ISO)
spindle  (IEA)
synapse  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Beites CL, etal., Nat Neurosci 1999 May;2(5):434-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Characterization of presynaptic septin complexes in mammalian hippocampal neurons. Tsang CW, etal., Biol Chem. 2011 Aug;392(8-9):739-49. doi: 10.1515/BC.2011.077. Epub 2011 Jul 19.
9. The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells. Vega IE and Hsu SC, Neuroreport 2003 Jan 20;14(1):31-7.
Additional References at PubMed
PMID:10942595   PMID:11739749   PMID:14723703   PMID:15489334   PMID:16371649   PMID:16641100   PMID:16854843   PMID:17634366   PMID:17637674   PMID:18809578   PMID:20458337   PMID:20558667  
PMID:21238513   PMID:22179047   PMID:23376485   PMID:23572511   PMID:24302887   PMID:25103794   PMID:25468996   PMID:25588830   PMID:25931508   PMID:35352799  


Genomics

Comparative Map Data
Septin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,465,535 - 101,498,766 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9101,465,650 - 101,498,759 (+)EnsemblGRCr8
mRatBN7.2994,018,141 - 94,051,386 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl994,018,208 - 94,051,386 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9102,453,742 - 102,486,891 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09107,589,577 - 107,622,561 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09105,945,723 - 105,978,707 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.09100,624,876 - 100,658,053 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9100,624,876 - 100,658,050 (+)Ensemblrn6Rnor6.0
Rnor_5.09100,277,885 - 100,311,082 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4992,756,091 - 92,789,257 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera991,552,840 - 91,585,967 (+)NCBICelera
RGSC_v3.1992,960,859 - 92,994,023 (+)NCBI
Cytogenetic Map9q36NCBI
SEPTIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382241,315,355 - 241,354,027 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2241,314,923 - 241,354,030 (+)Ensemblhg38GRCh38
GRCh372242,254,770 - 242,293,442 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362241,903,396 - 241,942,115 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342241,974,712 - 242,013,429NCBI
Celera2235,924,022 - 235,962,784 (+)NCBICelera
Cytogenetic Map2q37.3NCBI
HuRef2234,010,626 - 234,049,134 (+)NCBIHuRef
CHM1_12242,260,807 - 242,299,397 (+)NCBICHM1_1
T2T-CHM13v2.02241,814,341 - 241,852,889 (+)NCBIT2T-CHM13v2.0
Septin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39193,406,238 - 93,437,455 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl193,406,686 - 93,437,982 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38193,478,981 - 93,509,733 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl193,478,993 - 93,509,733 (+)Ensemblmm10GRCm38
GRCm38.p6 Ensembl193,478,964 - 93,510,260 (+)Ensemblmm10GRCm38
MGSCv37195,375,570 - 95,406,310 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36195,309,450 - 95,340,136 (+)NCBIMGSCv36mm8
Celera196,424,640 - 96,455,361 (+)NCBICelera
Cytogenetic Map1DNCBI
cM Map147.24NCBI
Septin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955542401,081 - 443,962 (-)Ensembl
ChiLan1.0NW_004955542401,081 - 444,304 (-)NCBIChiLan1.0ChiLan1.0
SEPTIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213144,018,107 - 144,056,524 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B144,033,004 - 144,067,595 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B128,586,659 - 128,624,991 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B247,380,771 - 247,419,556 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B247,380,771 - 247,419,556 (+)EnsemblpanPan2panpan1.1
SEPTIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12551,296,486 - 51,330,508 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2551,296,554 - 51,328,616 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2551,509,146 - 51,543,140 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02551,490,916 - 51,524,933 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2551,490,838 - 51,524,930 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12551,338,554 - 51,372,623 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02551,078,468 - 51,112,410 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02551,354,611 - 51,388,610 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Septin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303192,664,062 - 192,700,772 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936745518,391 - 546,953 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936745518,650 - 555,187 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPTIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15140,024,049 - 140,058,289 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115140,023,836 - 140,058,291 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215154,711,203 - 154,738,280 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEPTIN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110127,378,393 - 127,421,012 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10127,387,280 - 127,421,201 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604071,959,582 - 72,000,900 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Septin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248475,341,467 - 5,385,065 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248475,341,177 - 5,382,920 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Septin2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14165,410,785 - 165,444,069 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Septin2
129 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:469
Count of miRNA genes:246
Interacting mature miRNAs:305
Transcripts:ENSRNOT00000024261
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)986720043110356905Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)986720043121768150Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)968875497121768150Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)983161999118999486Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)985262459109044727Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)985262459118999486Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat

Markers in Region
RH128589  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2994,050,931 - 94,051,145 (+)MAPPERmRatBN7.2
Rnor_6.09100,657,599 - 100,657,812NCBIRnor6.0
Rnor_5.09100,310,628 - 100,310,841UniSTSRnor5.0
RGSC_v3.4992,788,803 - 92,789,016UniSTSRGSC3.4
Celera991,585,513 - 91,585,726UniSTS
Cytogenetic Map9q36UniSTS
AW535368  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2994,021,902 - 94,022,069 (+)MAPPERmRatBN7.2
Rnor_6.09100,628,571 - 100,628,737NCBIRnor6.0
Rnor_5.09100,281,600 - 100,281,766UniSTSRnor5.0
RGSC_v3.4992,759,774 - 92,759,940UniSTSRGSC3.4
Celera991,556,506 - 91,556,672UniSTS
RH 3.4 Map9809.2UniSTS
Cytogenetic Map9q36UniSTS
BF414279  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr89101,495,979 - 101,496,849 (+)Marker Load Pipeline
mRatBN7.2994,048,599 - 94,049,469 (+)MAPPERmRatBN7.2
Rnor_6.09100,655,267 - 100,656,136NCBIRnor6.0
Rnor_5.09100,308,296 - 100,309,165UniSTSRnor5.0
RGSC_v3.4992,786,471 - 92,787,340UniSTSRGSC3.4
Celera991,583,181 - 91,584,050UniSTS
RH 3.4 Map9811.5UniSTS
Cytogenetic Map9q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_057148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063266589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB027561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC081745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000024261   ⟹   ENSRNOP00000024261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9101,465,650 - 101,498,759 (+)Ensembl
mRatBN7.2 Ensembl994,018,208 - 94,051,386 (+)Ensembl
Rnor_6.0 Ensembl9100,624,876 - 100,658,050 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096521   ⟹   ENSRNOP00000081030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl9101,465,772 - 101,498,759 (+)Ensembl
mRatBN7.2 Ensembl994,018,426 - 94,051,159 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100613   ⟹   ENSRNOP00000087399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl994,018,434 - 94,051,386 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000111467   ⟹   ENSRNOP00000087317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl994,018,309 - 94,051,386 (+)Ensembl
RefSeq Acc Id: NM_057148   ⟹   NP_476489
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,617 - 101,498,766 (+)NCBI
mRatBN7.2994,018,237 - 94,051,386 (+)NCBI
Rnor_6.09100,624,876 - 100,658,053 (+)NCBI
Rnor_5.09100,277,885 - 100,311,082 (+)NCBI
RGSC_v3.4992,756,091 - 92,789,257 (+)RGD
Celera991,552,840 - 91,585,967 (+)RGD
Sequence:
RefSeq Acc Id: XM_006245514   ⟹   XP_006245576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,645 - 101,498,766 (+)NCBI
mRatBN7.2994,018,282 - 94,051,386 (+)NCBI
Rnor_6.09100,624,930 - 100,658,053 (+)NCBI
Rnor_5.09100,277,885 - 100,311,082 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039082963   ⟹   XP_038938891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,866 - 101,498,766 (+)NCBI
mRatBN7.2994,018,404 - 94,051,386 (+)NCBI
RefSeq Acc Id: XM_039082964   ⟹   XP_038938892
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,636 - 101,498,766 (+)NCBI
mRatBN7.2994,018,189 - 94,051,386 (+)NCBI
RefSeq Acc Id: XM_039082965   ⟹   XP_038938893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,467,060 - 101,498,766 (+)NCBI
mRatBN7.2994,019,759 - 94,051,386 (+)NCBI
RefSeq Acc Id: XM_039082966   ⟹   XP_038938894
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,866 - 101,498,766 (+)NCBI
mRatBN7.2994,018,401 - 94,051,386 (+)NCBI
RefSeq Acc Id: XM_063266585   ⟹   XP_063122655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,474,922 - 101,498,766 (+)NCBI
RefSeq Acc Id: XM_063266586   ⟹   XP_063122656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,475,030 - 101,498,766 (+)NCBI
RefSeq Acc Id: XM_063266587   ⟹   XP_063122657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,535 - 101,498,766 (+)NCBI
RefSeq Acc Id: XM_063266588   ⟹   XP_063122658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,465,645 - 101,498,766 (+)NCBI
RefSeq Acc Id: XM_063266589   ⟹   XP_063122659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr89101,486,465 - 101,498,766 (+)NCBI
RefSeq Acc Id: NP_476489   ⟸   NM_057148
- UniProtKB: Q91Y81 (UniProtKB/Swiss-Prot),   A6JR12 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245576   ⟸   XM_006245514
- Peptide Label: isoform X2
- UniProtKB: Q91Y81 (UniProtKB/Swiss-Prot),   A6JR12 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024261   ⟸   ENSRNOT00000024261
RefSeq Acc Id: XP_038938892   ⟸   XM_039082964
- Peptide Label: isoform X2
- UniProtKB: Q91Y81 (UniProtKB/Swiss-Prot),   A6JR12 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938894   ⟸   XM_039082966
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938891   ⟸   XM_039082963
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A7I8 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938893   ⟸   XM_039082965
- Peptide Label: isoform X2
- UniProtKB: Q91Y81 (UniProtKB/Swiss-Prot),   A6JR12 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000087399   ⟸   ENSRNOT00000100613
Ensembl Acc Id: ENSRNOP00000081030   ⟸   ENSRNOT00000096521
Ensembl Acc Id: ENSRNOP00000087317   ⟸   ENSRNOT00000111467
RefSeq Acc Id: XP_063122657   ⟸   XM_063266587
- Peptide Label: isoform X4
- UniProtKB: A0A8L2QCZ9 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122658   ⟸   XM_063266588
- Peptide Label: isoform X4
- UniProtKB: A0A8L2QCZ9 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122655   ⟸   XM_063266585
- Peptide Label: isoform X2
- UniProtKB: Q91Y81 (UniProtKB/Swiss-Prot),   A6JR12 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122656   ⟸   XM_063266586
- Peptide Label: isoform X2
- UniProtKB: Q91Y81 (UniProtKB/Swiss-Prot),   A6JR12 (UniProtKB/TrEMBL),   A0A8I5ZS15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063122659   ⟸   XM_063266589
- Peptide Label: isoform X5
Protein Domains
Septin-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91Y81-F1-model_v2 AlphaFold Q91Y81 1-361 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696876
Promoter ID:EPDNEW_R7401
Type:initiation region
Name:Sept2_1
Description:septin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.09100,624,899 - 100,624,959EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620056 AgrOrtholog
BioCyc Gene G2FUF-26640 BioCyc
Ensembl Genes ENSRNOG00000017952 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024261 ENTREZGENE
  ENSRNOT00000096521 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7121592 IMAGE-MGC_LOAD
InterPro G_SEPTIN_dom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  Septin UniProtKB/Swiss-Prot
  Septin2 UniProtKB/Swiss-Prot
KEGG Report rno:117515 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93254 IMAGE-MGC_LOAD
NCBI Gene 117515 ENTREZGENE
PANTHER SEPTIN UniProtKB/Swiss-Prot
Pfam Septin UniProtKB/Swiss-Prot
PhenoGen Septin2 PhenoGen
PIRSF Septin UniProtKB/Swiss-Prot
PRINTS SEPTIN2 UniProtKB/Swiss-Prot
PROSITE G_SEPTIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000017952 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8I5ZS15 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A7I8 ENTREZGENE
  A0A8L2QCZ9 ENTREZGENE, UniProtKB/TrEMBL
  A6JR12 ENTREZGENE, UniProtKB/TrEMBL
  Q91Y81 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Septin2  septin 2  Sept2  septin 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Sept2  septin 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 2-Sep  septin 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the perinuclear region 724634