Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | methylmalonic acidemia | | ISO | SEPTIN2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:16823967 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | methylmalonic acidemia | | ISO | SEPTIN2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:16823967 | |
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# | Reference Title | Reference Citation |
1. | The septin CDCrel-1 binds syntaxin and inhibits exocytosis. | Beites CL, etal., Nat Neurosci 1999 May;2(5):434-9. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
5. | GOA pipeline | RGD automated data pipeline |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
7. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
8. | The septin protein Nedd5 associates with both the exocyst complex and microtubules and disruption of its GTPase activity promotes aberrant neurite sprouting in PC12 cells. | Vega IE and Hsu SC, Neuroreport 2003 Jan 20;14(1):31-7. |
PMID:10942595 | PMID:11739749 | PMID:14723703 | PMID:15489334 | PMID:16371649 | PMID:16641100 | PMID:16854843 | PMID:17634366 | PMID:17637674 | PMID:18809578 | PMID:20458337 | PMID:20558667 |
PMID:21238513 | PMID:22179047 | PMID:23376485 | PMID:23572511 | PMID:24302887 | PMID:25103794 | PMID:25468996 | PMID:25588830 | PMID:25931508 | PMID:35352799 |
Septin2 (Rattus norvegicus - Norway rat) |
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SEPTIN2 (Homo sapiens - human) |
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Septin2 (Mus musculus - house mouse) |
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Septin2 (Chinchilla lanigera - long-tailed chinchilla) |
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SEPTIN2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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SEPTIN2 (Canis lupus familiaris - dog) |
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Septin2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SEPTIN2 (Sus scrofa - pig) |
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SEPTIN2 (Chlorocebus sabaeus - green monkey) |
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Septin2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Septin2
49 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH128589 |
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AW535368 |
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BF414279 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | |||||||||||||
Below cutoff |
RefSeq Transcripts | NM_057148 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006245514 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039082963 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039082964 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039082965 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039082966 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063266585 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063266586 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063266587 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063266588 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063266589 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB027561 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC081745 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473997 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ212097 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ228229 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000009 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000024261 ⟹ ENSRNOP00000024261 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000096521 ⟹ ENSRNOP00000081030 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000100613 ⟹ ENSRNOP00000087399 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000111467 ⟹ ENSRNOP00000087317 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_057148 ⟹ NP_476489 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006245514 ⟹ XP_006245576 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039082963 ⟹ XP_038938891 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039082964 ⟹ XP_038938892 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039082965 ⟹ XP_038938893 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039082966 ⟹ XP_038938894 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063266585 ⟹ XP_063122655 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063266586 ⟹ XP_063122656 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063266587 ⟹ XP_063122657 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063266588 ⟹ XP_063122658 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063266589 ⟹ XP_063122659 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_476489 | (Get FASTA) | NCBI Sequence Viewer |
XP_006245576 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038938891 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038938892 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038938893 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038938894 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063122655 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063122656 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063122657 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063122658 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063122659 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH81745 | (Get FASTA) | NCBI Sequence Viewer |
BAB47151 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91920 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91921 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91922 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91923 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91924 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91925 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91926 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91927 | (Get FASTA) | NCBI Sequence Viewer | |
EDL91928 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000024261 | ||
ENSRNOP00000024261.4 | |||
ENSRNOP00000081030.1 | |||
ENSRNOP00000087317 | |||
ENSRNOP00000087317.1 | |||
ENSRNOP00000087399.1 | |||
GenBank Protein | Q91Y81 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_476489 ⟸ NM_057148 |
- UniProtKB: | Q91Y81 (UniProtKB/Swiss-Prot), A6JR12 (UniProtKB/TrEMBL), A0A8I5ZS15 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006245576 ⟸ XM_006245514 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q91Y81 (UniProtKB/Swiss-Prot), A6JR12 (UniProtKB/TrEMBL), A0A8I5ZS15 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000024261 ⟸ ENSRNOT00000024261 |
RefSeq Acc Id: | XP_038938892 ⟸ XM_039082964 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q91Y81 (UniProtKB/Swiss-Prot), A6JR12 (UniProtKB/TrEMBL), A0A8I5ZS15 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038938894 ⟸ XM_039082966 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8L2QCZ9 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038938891 ⟸ XM_039082963 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6A7I8 (UniProtKB/TrEMBL), A0A8I5ZS15 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_038938893 ⟸ XM_039082965 |
- Peptide Label: | isoform X2 |
- UniProtKB: | Q91Y81 (UniProtKB/Swiss-Prot), A6JR12 (UniProtKB/TrEMBL), A0A8I5ZS15 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000087399 ⟸ ENSRNOT00000100613 |
RefSeq Acc Id: | ENSRNOP00000081030 ⟸ ENSRNOT00000096521 |
RefSeq Acc Id: | ENSRNOP00000087317 ⟸ ENSRNOT00000111467 |
RefSeq Acc Id: | XP_063122657 ⟸ XM_063266587 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063122658 ⟸ XM_063266588 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063122655 ⟸ XM_063266585 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063122656 ⟸ XM_063266586 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063122659 ⟸ XM_063266589 |
- Peptide Label: | isoform X5 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q91Y81-F1-model_v2 | AlphaFold | Q91Y81 | 1-361 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13696876 | ||||||||
Promoter ID: | EPDNEW_R7401 | ||||||||
Type: | initiation region | ||||||||
Name: | Sept2_1 | ||||||||
Description: | septin 2 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:620056 | AgrOrtholog |
BioCyc Gene | G2FUF-26640 | BioCyc |
Ensembl Genes | ENSRNOG00000017952 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000024261 | ENTREZGENE |
ENSRNOT00000024261.5 | UniProtKB/TrEMBL | |
ENSRNOT00000096521.1 | UniProtKB/TrEMBL | |
ENSRNOT00000100613.1 | UniProtKB/TrEMBL | |
ENSRNOT00000111467.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.40.50.300 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7121592 | IMAGE-MGC_LOAD |
InterPro | G_SEPTIN_dom | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
P-loop_NTPase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Septin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Septin2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:117515 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:93254 | IMAGE-MGC_LOAD |
NCBI Gene | 117515 | ENTREZGENE |
PANTHER | SEPTIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SEPTIN-2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Septin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PhenoGen | Septin2 | PhenoGen |
PIRSF | Septin | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PRINTS | SEPTIN2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PROSITE | G_SEPTIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000017952 | RatGTEx |
Superfamily-SCOP | SSF52540 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A8I5ZS15 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6A7I8 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6GF37_RAT | UniProtKB/TrEMBL | |
A0A8L2QCZ9 | ENTREZGENE, UniProtKB/TrEMBL | |
A6JR12 | ENTREZGENE, UniProtKB/TrEMBL | |
Q91Y81 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2019-08-05 | Septin2 | septin 2 | Sept2 | septin 2 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-20 | Sept2 | septin 2 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
2002-08-07 | 2-Sep | septin 2 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_cellular_localization | localized to the perinuclear region | 724634 |