Dedd (death effector domain-containing) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dedd (death effector domain-containing) Rattus norvegicus
Analyze
Symbol: Dedd
Name: death effector domain-containing
RGD ID: 620050
Description: Predicted to enable DNA binding activity. Involved in spermatogenesis. Predicted to be located in cytoplasm. Predicted to be active in nucleolus. Orthologous to human DEDD (death effector domain containing); INTERACTS WITH 1,2-dimethylhydrazine; aflatoxin B1; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: death effector domain-containing protein; death effector domain-containing testicular molecule; Deft
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,286,341 - 86,301,789 (+)NCBIGRCr8
mRatBN7.21383,755,874 - 83,769,982 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,756,108 - 83,769,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,271,346 - 86,274,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,669,556 - 87,672,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,905,654 - 84,909,025 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,706,932 - 89,721,825 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,718,066 - 89,721,454 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,335,810 - 94,349,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,238,315 - 87,241,703 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,427,198 - 87,430,587 (+)NCBI
Celera1383,396,267 - 83,399,655 (+)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
nucleolus  (IBA,ISO,ISS)

Molecular Function
DNA binding  (IBA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. DEFT, a novel death effector domain-containing molecule predominantly expressed in testicular germ cells. Leo CP, etal., Endocrinology 1998 Dec;139(12):4839-48.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. DEDD, a novel death effector domain-containing protein, targeted to the nucleolus. Stegh AH, etal., EMBO J 1998 Oct 15;17(20):5974-86.
Additional References at PubMed
PMID:21135503  


Genomics

Comparative Map Data
Dedd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,286,341 - 86,301,789 (+)NCBIGRCr8
mRatBN7.21383,755,874 - 83,769,982 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,756,108 - 83,769,332 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,271,346 - 86,274,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,669,556 - 87,672,945 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,905,654 - 84,909,025 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,706,932 - 89,721,825 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,718,066 - 89,721,454 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,335,810 - 94,349,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,238,315 - 87,241,703 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11387,427,198 - 87,430,587 (+)NCBI
Celera1383,396,267 - 83,399,655 (+)NCBICelera
Cytogenetic Map13q24NCBI
DEDD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,120,974 - 161,132,667 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,120,974 - 161,132,688 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,090,764 - 161,102,457 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,357,391 - 159,369,102 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,904,194 - 157,915,454NCBI
Celera1134,157,929 - 134,169,640 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,448,171 - 132,459,535 (-)NCBIHuRef
CHM1_11162,487,014 - 162,498,725 (-)NCBICHM1_1
T2T-CHM13v2.01160,258,449 - 160,270,142 (-)NCBIT2T-CHM13v2.0
Dedd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,152,229 - 171,170,843 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,156,713 - 171,169,899 (+)EnsemblGRCm39 Ensembl
GRCm381171,324,661 - 171,342,501 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,329,145 - 171,342,331 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,259,276 - 173,272,632 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,166,186 - 173,178,290 (+)NCBIMGSCv36mm8
Celera1173,780,626 - 173,793,989 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.34NCBI
Dedd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,885,553 - 12,897,164 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,885,547 - 12,897,522 (-)NCBIChiLan1.0ChiLan1.0
DEDD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,719,267 - 88,730,685 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,409,605 - 88,421,020 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,533,756 - 136,545,107 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,446,657 - 140,459,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,447,011 - 140,457,876 (-)Ensemblpanpan1.1panPan2
DEDD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,341,101 - 21,351,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,342,534 - 21,351,972 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,414,740 - 21,426,365 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,458,228 - 21,469,858 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,458,401 - 21,469,854 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,346,398 - 21,358,014 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,760,422 - 21,772,037 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,169,639 - 22,181,267 (+)NCBIUU_Cfam_GSD_1.0
Dedd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,227,940 - 7,239,927 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903435,447 - 448,025 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903436,949 - 448,670 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEDD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,311,310 - 89,323,724 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,311,308 - 89,323,692 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,168,043 - 97,180,622 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEDD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,848,294 - 2,858,746 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,848,510 - 2,858,618 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,895,667 - 1,907,143 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dedd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794244,068 - 255,110 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794243,584 - 254,495 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dedd
51 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:35
Count of miRNA genes:33
Interacting mature miRNAs:35
Transcripts:ENSRNOT00000005147
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 57 41 19 41 8 11 74 35 41 11 8
Low 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF053362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000005147   ⟹   ENSRNOP00000005147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1383,756,108 - 83,769,332 (+)Ensembl
Rnor_6.0 Ensembl1389,718,066 - 89,721,454 (+)Ensembl
RefSeq Acc Id: NM_031800   ⟹   NP_113988
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,298,030 - 86,301,418 (+)NCBI
mRatBN7.21383,765,584 - 83,768,972 (+)NCBI
Rnor_6.01389,718,066 - 89,721,454 (+)NCBI
Rnor_5.01394,335,810 - 94,349,158 (+)NCBI
RGSC_v3.41387,238,315 - 87,241,703 (+)RGD
Celera1383,396,267 - 83,399,655 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250269   ⟹   XP_006250331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
mRatBN7.21383,755,874 - 83,769,981 (+)NCBI
Rnor_6.01389,706,932 - 89,721,825 (+)NCBI
Rnor_5.01394,335,810 - 94,349,158 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250272   ⟹   XP_006250334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,506 - 86,301,789 (+)NCBI
mRatBN7.21383,756,070 - 83,769,982 (+)NCBI
Rnor_6.01389,708,555 - 89,721,825 (+)NCBI
Rnor_5.01394,335,810 - 94,349,158 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250274   ⟹   XP_006250336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
mRatBN7.21383,755,874 - 83,769,981 (+)NCBI
Rnor_6.01389,706,932 - 89,721,825 (+)NCBI
Rnor_5.01394,335,810 - 94,349,158 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598942   ⟹   XP_017454431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
mRatBN7.21383,755,874 - 83,769,981 (+)NCBI
Rnor_6.01389,706,932 - 89,721,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598943   ⟹   XP_017454432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
mRatBN7.21383,755,874 - 83,769,981 (+)NCBI
Rnor_6.01389,706,932 - 89,721,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598944   ⟹   XP_017454433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,549 - 86,301,789 (+)NCBI
mRatBN7.21383,756,108 - 83,769,982 (+)NCBI
Rnor_6.01389,708,555 - 89,721,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598945   ⟹   XP_017454434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
mRatBN7.21383,755,874 - 83,769,981 (+)NCBI
Rnor_6.01389,706,932 - 89,721,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598946   ⟹   XP_017454435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,532 - 86,301,789 (+)NCBI
mRatBN7.21383,756,096 - 83,769,982 (+)NCBI
Rnor_6.01389,708,555 - 89,721,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091125   ⟹   XP_038947053
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,461 - 86,301,789 (+)NCBI
mRatBN7.21383,756,108 - 83,769,982 (+)NCBI
RefSeq Acc Id: XM_063272643   ⟹   XP_063128713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,914 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272644   ⟹   XP_063128714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272645   ⟹   XP_063128715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,914 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272646   ⟹   XP_063128716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,286,341 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272647   ⟹   XP_063128717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,559 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272648   ⟹   XP_063128718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,556 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272649   ⟹   XP_063128719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,914 - 86,301,789 (+)NCBI
RefSeq Acc Id: XM_063272650   ⟹   XP_063128720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81386,288,620 - 86,301,789 (+)NCBI
Protein Sequences
Protein RefSeqs NP_113988 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250331 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250334 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250336 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454431 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454432 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454433 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454434 (Get FASTA)   NCBI Sequence Viewer  
  XP_017454435 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947053 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128713 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128714 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128715 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128716 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128717 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128718 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128719 (Get FASTA)   NCBI Sequence Viewer  
  XP_063128720 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC80287 (Get FASTA)   NCBI Sequence Viewer  
  EDL94632 (Get FASTA)   NCBI Sequence Viewer  
  EDL94633 (Get FASTA)   NCBI Sequence Viewer  
  EDL94634 (Get FASTA)   NCBI Sequence Viewer  
  EDL94635 (Get FASTA)   NCBI Sequence Viewer  
  EDL94636 (Get FASTA)   NCBI Sequence Viewer  
  EDL94637 (Get FASTA)   NCBI Sequence Viewer  
  EDL94638 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005147
  ENSRNOP00000005147.1
  ENSRNOP00055031194
  ENSRNOP00060023985
  ENSRNOP00065030908
GenBank Protein Q9Z2K0 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113988   ⟸   NM_031800
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250331   ⟸   XM_006250269
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250336   ⟸   XM_006250274
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250334   ⟸   XM_006250272
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454431   ⟸   XM_017598942
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454434   ⟸   XM_017598945
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454432   ⟸   XM_017598943
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454433   ⟸   XM_017598944
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454435   ⟸   XM_017598946
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005147   ⟸   ENSRNOT00000005147
RefSeq Acc Id: XP_038947053   ⟸   XM_039091125
- Peptide Label: isoform X1
- UniProtKB: Q9Z2K0 (UniProtKB/Swiss-Prot),   A6JFX6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128714   ⟸   XM_063272644
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128716   ⟸   XM_063272646
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128718   ⟸   XM_063272648
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128717   ⟸   XM_063272647
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128720   ⟸   XM_063272650
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128719   ⟸   XM_063272649
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128715   ⟸   XM_063272645
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063128713   ⟸   XM_063272643
- Peptide Label: isoform X1
Protein Domains
DED

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2K0-F1-model_v2 AlphaFold Q9Z2K0 1-318 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620050 AgrOrtholog
BioCyc Gene G2FUF-17374 BioCyc
Ensembl Genes ENSRNOG00000003779 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055022296 UniProtKB/Swiss-Prot
  ENSRNOG00060017425 UniProtKB/Swiss-Prot
  ENSRNOG00065022384 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005147.3 UniProtKB/Swiss-Prot
  ENSRNOT00055038315 UniProtKB/Swiss-Prot
  ENSRNOT00060029768 UniProtKB/Swiss-Prot
  ENSRNOT00065038175 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.533.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DED_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DEDD/DEDD2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRADD-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83631 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 83631 ENTREZGENE
PANTHER DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PTHR15205 UniProtKB/Swiss-Prot
Pfam DED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRADD-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dedd PhenoGen
PROSITE DED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003779 RatGTEx
  ENSRNOG00055022296 RatGTEx
  ENSRNOG00060017425 RatGTEx
  ENSRNOG00065022384 RatGTEx
SMART DED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP DEATH domain UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6JFX6 ENTREZGENE, UniProtKB/TrEMBL
  DEDD_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Dedd  death effector domain-containing    death effector domain-containing protein  Name updated 1299863 APPROVED
2002-08-07 Dedd  death effector domain-containing protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in a variety of tissues, abundant in testis 632570
gene_regulation mRNA increased in testis of immature rats after 2 days of treatment with a GnRH antagonist 632570