Serbp1 (Serpine1 mRNA binding protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Serbp1 (Serpine1 mRNA binding protein 1) Rattus norvegicus
Analyze
Symbol: Serbp1
Name: Serpine1 mRNA binding protein 1
RGD ID: 619907
Description: Predicted to enable several functions, including SUMO binding activity; mRNA 3'-UTR binding activity; and translation elongation factor binding activity. Involved in regulation of apoptotic process. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human SERBP1 (SERPINE1 mRNA binding protein 1); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: hypothetical RNA binding protein RDA288; MGC94773; PAI-1 mRNA-binding protein; Pai-Rbp1; PAI1 RNA-binding protein 1; Pairbp1; plasminogen activator inhibitor 1 RNA-binding protein; Rda288; RNA binding protein RDA288; SERPINE1 mRNA-binding protein 1; similar to human CGI-55
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8497,731,200 - 97,748,438 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl497,731,277 - 97,751,518 (+)EnsemblGRCr8
mRatBN7.2496,401,587 - 96,421,816 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,401,477 - 96,421,813 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4101,657,488 - 101,674,308 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,432,460 - 97,449,280 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0495,856,345 - 95,873,167 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,027,563 - 98,044,717 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,027,554 - 98,044,566 (+)Ensemblrn6Rnor6.0
Rnor_5.04162,813,176 - 162,830,315 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4496,904,328 - 96,921,186 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera491,093,862 - 91,110,720 (+)NCBICelera
RGSC_v3.1497,148,802 - 97,165,651 (+)NCBI
Cytogenetic Map4q31NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxynon-2-enal  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
Chorionic gonadotropin  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-nitrosodiethylamine  (EXP)
nickel subsulfide  (EXP)
nickel sulfate  (ISO)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pinosylvin  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
succimer  (ISO)
tamibarotene  (ISO)
testosterone enanthate  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
trans-pinosylvin  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)
perinuclear region of cytoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
3. Involvement of an unnamed protein, RDA288, in the mechanism through which progesterone mediates its antiapoptotic action in spontaneously immortalized granulosa cells. Peluso JJ, etal., Endocrinology 2004 Jun;145(6):3014-22. Epub 2004 Feb 26.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1639225   PMID:11001948   PMID:12112363   PMID:12477932   PMID:15489334   PMID:15814896   PMID:16879614   PMID:19946888   PMID:20458337   PMID:22658674   PMID:22681889   PMID:23242527  
PMID:25468996   PMID:28695742   PMID:31904090   PMID:35352799  


Genomics

Comparative Map Data
Serbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8497,731,200 - 97,748,438 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl497,731,277 - 97,751,518 (+)EnsemblGRCr8
mRatBN7.2496,401,587 - 96,421,816 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl496,401,477 - 96,421,813 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4101,657,488 - 101,674,308 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0497,432,460 - 97,449,280 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0495,856,345 - 95,873,167 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0498,027,563 - 98,044,717 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl498,027,554 - 98,044,566 (+)Ensemblrn6Rnor6.0
Rnor_5.04162,813,176 - 162,830,315 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4496,904,328 - 96,921,186 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera491,093,862 - 91,110,720 (+)NCBICelera
RGSC_v3.1497,148,802 - 97,165,651 (+)NCBI
Cytogenetic Map4q31NCBI
SERBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38167,407,810 - 67,430,402 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl167,407,810 - 67,430,415 (-)Ensemblhg38GRCh38
GRCh37167,873,493 - 67,896,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36167,646,081 - 67,668,711 (-)NCBIBuild 36Build 36hg18NCBI36
Celera166,163,237 - 66,185,855 (-)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef165,983,382 - 66,005,913 (-)NCBIHuRef
CHM1_1167,988,850 - 68,011,473 (-)NCBICHM1_1
T2T-CHM13v2.0167,285,390 - 67,307,973 (-)NCBIT2T-CHM13v2.0
Serbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39667,243,963 - 67,266,286 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl667,215,160 - 67,274,720 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38667,266,979 - 67,289,302 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl667,238,176 - 67,297,736 (+)Ensemblmm10GRCm38
MGSCv37667,216,973 - 67,239,296 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36667,196,557 - 67,215,541 (+)NCBIMGSCv36mm8
Celera669,389,555 - 69,411,847 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map630.8NCBI
Serbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542323,762,916 - 23,774,160 (+)Ensembl
ChiLan1.0NW_00495542323,763,356 - 23,774,816 (+)NCBIChiLan1.0ChiLan1.0
SERBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21159,436,944 - 159,456,718 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11158,596,767 - 158,616,513 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0166,652,473 - 66,671,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1168,509,843 - 68,531,911 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl168,509,843 - 68,531,911 (+)EnsemblpanPan2panpan1.1
SERBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1543,170,553 - 43,187,281 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl543,170,574 - 43,185,234 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha543,358,617 - 43,375,343 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0543,355,492 - 43,372,233 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl543,355,542 - 43,372,182 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1543,321,865 - 43,338,605 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0543,268,524 - 43,285,249 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0543,507,528 - 43,524,261 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Serbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505880,257,576 - 80,274,788 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365914,214,767 - 4,231,973 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365914,214,770 - 4,231,973 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SERBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6145,186,736 - 145,203,915 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.16145,186,551 - 145,201,781 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26134,068,962 - 134,084,044 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SERBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12065,673,539 - 65,699,963 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2065,673,450 - 65,697,828 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603351,909,969 - 51,932,020 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Serbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474227,788,319 - 27,830,606 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474227,813,538 - 27,828,800 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Serbp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1676,814,694 - 76,834,807 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Serbp1
118 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:57
Interacting mature miRNAs:80
Transcripts:ENSRNOT00000009503
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582232Gluco25Glucose level QTL 253.60.0023blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)486583980149763391Rat
631689Scl4Serum cholesterol level QTL 41.90.008blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)496731383141731383Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
1578655Bmd11Bone mineral density QTL 1111femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)492406430137406430Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)480212111119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
2317587Eae26Experimental allergic encephalomyelitis QTL 26nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)489986808101226978Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)480216705104243248Rat
1578670Bss14Bone structure and strength QTL 1416.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)488883695133883695Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
1578662Bss15Bone structure and strength QTL 1519.6femur width (VT:1000666)femoral neck width (CMO:0001695)488883695133883695Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
634334Xhs3X-ray hypersensitivity QTL 310intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)486058928131411333Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)484349032129349032Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)482336765127336765Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
12798523Anxrr56Anxiety related response QTL 562.830.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)486583980131583980Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat

Markers in Region
G43269  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2496,418,624 - 96,418,732 (+)MAPPERmRatBN7.2
Rnor_6.0498,044,597 - 98,044,704NCBIRnor6.0
Rnor_5.04162,830,207 - 162,830,314UniSTSRnor5.0
RGSC_v3.4496,921,311 - 96,921,418UniSTSRGSC3.4
Celera491,110,845 - 91,110,952UniSTS
Cytogenetic Map4q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF388527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231329 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ235054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U21718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000009503   ⟹   ENSRNOP00000009503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl497,731,277 - 97,751,518 (+)Ensembl
mRatBN7.2 Ensembl496,401,614 - 96,418,484 (+)Ensembl
Rnor_6.0 Ensembl498,027,554 - 98,044,566 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103052   ⟹   ENSRNOP00000092207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl497,731,277 - 97,751,518 (+)Ensembl
mRatBN7.2 Ensembl496,401,611 - 96,421,813 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106917   ⟹   ENSRNOP00000086511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl497,731,277 - 97,751,518 (+)Ensembl
mRatBN7.2 Ensembl496,401,625 - 96,421,810 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120247   ⟹   ENSRNOP00000080517
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl497,731,277 - 97,746,724 (+)Ensembl
mRatBN7.2 Ensembl496,401,477 - 96,417,031 (+)Ensembl
RefSeq Acc Id: NM_145086   ⟹   NP_659554
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,731,335 - 97,748,193 (+)NCBI
mRatBN7.2496,401,641 - 96,418,500 (+)NCBI
Rnor_6.0498,027,614 - 98,044,472 (+)NCBI
Rnor_5.04162,813,176 - 162,830,315 (+)NCBI
RGSC_v3.4496,904,328 - 96,921,186 (+)RGD
Celera491,093,862 - 91,110,720 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236616   ⟹   XP_006236678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,731,200 - 97,748,438 (+)NCBI
mRatBN7.2496,401,588 - 96,421,816 (+)NCBI
Rnor_6.0498,027,563 - 98,044,717 (+)NCBI
Rnor_5.04162,813,176 - 162,830,315 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236617   ⟹   XP_006236679
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,731,200 - 97,748,438 (+)NCBI
mRatBN7.2496,401,588 - 96,421,816 (+)NCBI
Rnor_6.0498,027,563 - 98,044,717 (+)NCBI
Rnor_5.04162,813,176 - 162,830,315 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236618   ⟹   XP_006236680
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,731,200 - 97,748,438 (+)NCBI
mRatBN7.2496,401,587 - 96,421,816 (+)NCBI
Rnor_6.0498,027,564 - 98,044,717 (+)NCBI
Rnor_5.04162,813,176 - 162,830,315 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107049   ⟹   XP_038962977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8497,731,200 - 97,748,438 (+)NCBI
mRatBN7.2496,401,588 - 96,421,816 (+)NCBI
RefSeq Acc Id: NP_659554   ⟸   NM_145086
- UniProtKB: A6KF48 (UniProtKB/TrEMBL),   A0A8I6G6Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236678   ⟸   XM_006236616
- Peptide Label: isoform X1
- UniProtKB: Q8VHU3 (UniProtKB/Swiss-Prot),   Q6AXS5 (UniProtKB/Swiss-Prot),   A6KF47 (UniProtKB/TrEMBL),   A0A8I6G6Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236679   ⟸   XM_006236617
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G6Q3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236680   ⟸   XM_006236618
- Peptide Label: isoform X3
- UniProtKB: A0A8I6G6Q3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009503   ⟸   ENSRNOT00000009503
RefSeq Acc Id: XP_038962977   ⟸   XM_039107049
- Peptide Label: isoform X4
- UniProtKB: A0A8L2Q518 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000080517   ⟸   ENSRNOT00000120247
Ensembl Acc Id: ENSRNOP00000086511   ⟸   ENSRNOT00000106917
Ensembl Acc Id: ENSRNOP00000092207   ⟸   ENSRNOT00000103052
Protein Domains
Hyaluronan/mRNA-binding protein   Intracellular hyaluronan-binding protein 4 N-

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXS5-F1-model_v2 AlphaFold Q6AXS5 1-407 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693103
Promoter ID:EPDNEW_R3627
Type:multiple initiation site
Name:Serbp1_1
Description:Serpine1 mRNA binding protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0498,027,593 - 98,027,653EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619907 AgrOrtholog
BioCyc Gene G2FUF-44565 BioCyc
Ensembl Genes ENSRNOG00000005890 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009503 ENTREZGENE
  ENSRNOT00000106917 ENTREZGENE
  ENSRNOT00000106917.1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7106027 IMAGE-MGC_LOAD
InterPro HABP4/SERBP1 UniProtKB/Swiss-Prot
  HABP4_PAIRBP1-bd UniProtKB/Swiss-Prot
  IHABP4_N UniProtKB/Swiss-Prot
KEGG Report rno:246303 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94773 IMAGE-MGC_LOAD
NCBI Gene 246303 ENTREZGENE
PANTHER PTHR12299 UniProtKB/Swiss-Prot
  PTHR12299:SF29 UniProtKB/Swiss-Prot
Pfam HABP4_PAI-RBP1 UniProtKB/Swiss-Prot
  IHABP4_N UniProtKB/Swiss-Prot
PhenoGen Serbp1 PhenoGen
RatGTEx ENSRNOG00000005890 RatGTEx
SMART HABP4_PAI-RBP1 UniProtKB/Swiss-Prot
UniProt A0A8I6AF25_RAT UniProtKB/TrEMBL
  A0A8I6G6Q3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q518 ENTREZGENE, UniProtKB/TrEMBL
  A6KF47 ENTREZGENE, UniProtKB/TrEMBL
  A6KF48 ENTREZGENE, UniProtKB/TrEMBL
  A6KF49_RAT UniProtKB/TrEMBL
  PAIRB_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8VHU3 ENTREZGENE
UniProt Secondary Q8VHU3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Serbp1  Serpine1 mRNA binding protein 1  Pairbp1  PAI-1 mRNA-binding protein  Symbol and Name updated 1299863 APPROVED
2005-01-20 Pairbp1  PAI-1 mRNA-binding protein  Rda288  hypothetical RNA binding protein RDA288  Symbol and Name updated 1299863 APPROVED
2002-08-07 Rda288  hypothetical RNA binding protein RDA288      Symbol and Name status set to provisional 70820 PROVISIONAL