Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mark3 | Rat | visual impairment and progressive phthisis bulbi | | ISO | MARK3 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mark3 | Rat | visual impairment and progressive phthisis bulbi | | ISO | MARK3 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 3. | C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. | Peng CY, etal., Cell Growth Differ. 1998 Mar;9(3):197-208. |
| 4. | GOA pipeline | RGD automated data pipeline |
| 5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 7. | Information Derived from GenBank Report | RGD, Sept. 2003 |
| PMID:16980613 | PMID:18570454 | PMID:21145462 | PMID:23666762 | PMID:25931508 | PMID:28087714 |
| Mark3 (Rattus norvegicus - Norway rat) |
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| MARK3 (Homo sapiens - human) |
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| Mark3 (Mus musculus - house mouse) |
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| Mark3 (Chinchilla lanigera - long-tailed chinchilla) |
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| MARK3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| MARK3 (Canis lupus familiaris - dog) |
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| Mark3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| MARK3 (Sus scrofa - pig) |
No map positions available. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| MARK3 (Chlorocebus sabaeus - green monkey) |
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| Mark3 (Heterocephalus glaber - naked mole-rat) |
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| Mark3 (Rattus rattus - black rat) |
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Variants in Mark3
4809 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| BE120426 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 165 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 144 | 81 | 92 | 31 | 17 | 17 |
| RefSeq Transcripts | NM_130749 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006240563 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006240564 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594010 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594011 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594012 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594014 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594015 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594017 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017594018 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111715 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111717 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111718 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111720 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111721 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111723 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111724 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039111725 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261495 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261496 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261497 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261498 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261499 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261500 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261501 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261502 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063261503 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AF465412 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| CH474034 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ214295 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ235189 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000006 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000014395 ⟹ ENSRNOP00000014395 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000080304 ⟹ ENSRNOP00000068972 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000088784 ⟹ ENSRNOP00000073297 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000092806 ⟹ ENSRNOP00000075961 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000094828 ⟹ ENSRNOP00000091306 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000105097 ⟹ ENSRNOP00000082974 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_130749 ⟹ NP_570105 | ||||||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_006240563 ⟹ XP_006240625 | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017594010 ⟹ XP_017449499 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017594011 ⟹ XP_017449500 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039111715 ⟹ XP_038967643 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111717 ⟹ XP_038967645 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111718 ⟹ XP_038967646 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111720 ⟹ XP_038967648 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111721 ⟹ XP_038967649 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111723 ⟹ XP_038967651 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111724 ⟹ XP_038967652 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039111725 ⟹ XP_038967653 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261495 ⟹ XP_063117565 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261496 ⟹ XP_063117566 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261497 ⟹ XP_063117567 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261498 ⟹ XP_063117568 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261499 ⟹ XP_063117569 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261500 ⟹ XP_063117570 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261501 ⟹ XP_063117571 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261502 ⟹ XP_063117572 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063261503 ⟹ XP_063117573 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_570105 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006240625 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449499 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017449500 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967643 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967645 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967646 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967648 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967649 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967651 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967652 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038967653 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117565 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117566 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117567 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117568 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117569 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117570 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117571 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117572 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063117573 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAL69981 | (Get FASTA) | NCBI Sequence Viewer |
| EDL97458 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL97459 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL97460 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL97461 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL97462 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000014395 | ||
| ENSRNOP00000068972 | |||
| ENSRNOP00000073297 | |||
| GenBank Protein | Q8VHF0 | (Get FASTA) | NCBI Sequence Viewer |
| RefSeq Acc Id: | NP_570105 ⟸ NM_130749 |
| - UniProtKB: | Q8VHF0 (UniProtKB/Swiss-Prot), A0A0G2K554 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_006240625 ⟸ XM_006240563 |
| - Peptide Label: | isoform X6 |
| - UniProtKB: | A0A0G2K554 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_017449500 ⟸ XM_017594011 |
| - Peptide Label: | isoform X2 |
| - UniProtKB: | A6KBR9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_017449499 ⟸ XM_017594010 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A6KBR9 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000068972 ⟸ ENSRNOT00000080304 |
| Ensembl Acc Id: | ENSRNOP00000075961 ⟸ ENSRNOT00000092806 |
| Ensembl Acc Id: | ENSRNOP00000014395 ⟸ ENSRNOT00000014395 |
| Ensembl Acc Id: | ENSRNOP00000073297 ⟸ ENSRNOT00000088784 |
| RefSeq Acc Id: | XP_038967651 ⟸ XM_039111723 |
| - Peptide Label: | isoform X18 |
| RefSeq Acc Id: | XP_038967649 ⟸ XM_039111721 |
| - Peptide Label: | isoform X12 |
| - UniProtKB: | A0A0G2K554 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038967646 ⟸ XM_039111718 |
| - Peptide Label: | isoform X7 |
| - UniProtKB: | F1M836 (UniProtKB/TrEMBL), A0A0G2K554 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038967643 ⟸ XM_039111715 |
| - Peptide Label: | isoform X4 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038967645 ⟸ XM_039111717 |
| - Peptide Label: | isoform X5 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038967648 ⟸ XM_039111720 |
| - Peptide Label: | isoform X9 |
| RefSeq Acc Id: | XP_038967652 ⟸ XM_039111724 |
| - Peptide Label: | isoform X19 |
| RefSeq Acc Id: | XP_038967653 ⟸ XM_039111725 |
| - Peptide Label: | isoform X20 |
| Ensembl Acc Id: | ENSRNOP00000091306 ⟸ ENSRNOT00000094828 |
| Ensembl Acc Id: | ENSRNOP00000082974 ⟸ ENSRNOT00000105097 |
| RefSeq Acc Id: | XP_063117565 ⟸ XM_063261495 |
| - Peptide Label: | isoform X3 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117566 ⟸ XM_063261496 |
| - Peptide Label: | isoform X8 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117567 ⟸ XM_063261497 |
| - Peptide Label: | isoform X10 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117568 ⟸ XM_063261498 |
| - Peptide Label: | isoform X11 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117570 ⟸ XM_063261500 |
| - Peptide Label: | isoform X14 |
| - UniProtKB: | A0A8I6GIW6 (UniProtKB/TrEMBL), A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117572 ⟸ XM_063261502 |
| - Peptide Label: | isoform X16 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117573 ⟸ XM_063261503 |
| - Peptide Label: | isoform X17 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117571 ⟸ XM_063261501 |
| - Peptide Label: | isoform X15 |
| - UniProtKB: | A0A0G2K554 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063117569 ⟸ XM_063261499 |
| - Peptide Label: | isoform X13 |
| - UniProtKB: | A0A0G2JU56 (UniProtKB/TrEMBL) |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-Q8VHF0-F1-model_v2 | AlphaFold | Q8VHF0 | 1-797 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:619883 | AgrOrtholog |
| BioCyc Gene | G2FUF-35837 | BioCyc |
| Ensembl Genes | ENSRNOG00000010330 | Ensembl, ENTREZGENE |
| Ensembl Transcript | ENSRNOT00000014395 | ENTREZGENE |
| ENSRNOT00000080304 | ENTREZGENE | |
| ENSRNOT00000088784 | ENTREZGENE | |
| Gene3D-CATH | DNA helicase RuvA subunit, C-terminal domain | UniProtKB/Swiss-Prot |
| Kinase associated domain 1, KA1 | UniProtKB/Swiss-Prot | |
| Phosphorylase Kinase, domain 1 | UniProtKB/Swiss-Prot | |
| Transferase(Phosphotransferase) domain 1 | UniProtKB/Swiss-Prot | |
| InterPro | KA1/Ssp2_C | UniProtKB/Swiss-Prot |
| KA1_dom | UniProtKB/Swiss-Prot | |
| Kinase-like_dom_sf | UniProtKB/Swiss-Prot | |
| MARK1-4_cat | UniProtKB/Swiss-Prot | |
| Prot_kinase_dom | UniProtKB/Swiss-Prot | |
| Protein_kinase_ATP_BS | UniProtKB/Swiss-Prot | |
| Ser/Thr_kinase_AS | UniProtKB/Swiss-Prot | |
| UBA | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:170577 | UniProtKB/Swiss-Prot |
| NCBI Gene | 170577 | ENTREZGENE |
| PANTHER | MAP/MICROTUBULE AFFINITY-REGULATING KINASE | UniProtKB/Swiss-Prot |
| PTHR24346:SF1 | UniProtKB/Swiss-Prot | |
| Pfam | KA1 | UniProtKB/Swiss-Prot |
| Pkinase | UniProtKB/Swiss-Prot | |
| UBA | UniProtKB/Swiss-Prot | |
| PhenoGen | Mark3 | PhenoGen |
| PROSITE | KA1 | UniProtKB/Swiss-Prot |
| PROTEIN_KINASE_ATP | UniProtKB/Swiss-Prot | |
| PROTEIN_KINASE_DOM | UniProtKB/Swiss-Prot | |
| PROTEIN_KINASE_ST | UniProtKB/Swiss-Prot | |
| UBA | UniProtKB/Swiss-Prot | |
| RatGTEx | ENSRNOG00000010330 | RatGTEx |
| SMART | S_TKc | UniProtKB/Swiss-Prot |
| UBA | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF103243 | UniProtKB/Swiss-Prot |
| SSF56112 | UniProtKB/Swiss-Prot | |
| UniProt | A0A0G2JU56 | ENTREZGENE, UniProtKB/TrEMBL |
| A0A0G2K554 | ENTREZGENE, UniProtKB/TrEMBL | |
| A0A1B0GWN5_RAT | UniProtKB/TrEMBL | |
| A0A8I5ZV33_RAT | UniProtKB/TrEMBL | |
| A0A8I6GIW6 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6KBR9 | ENTREZGENE, UniProtKB/TrEMBL | |
| A6KBS0_RAT | UniProtKB/TrEMBL | |
| A6KBS3_RAT | UniProtKB/TrEMBL | |
| F1M836 | ENTREZGENE, UniProtKB/TrEMBL | |
| MARK3_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2016-02-17 | Mark3 | microtubule affinity regulating kinase 3 | Mark3 | MAP/microtubule affinity-regulating kinase 3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2004-09-10 | Mark3 | MAP/microtubule affinity-regulating kinase 3 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
| 2002-08-07 | Mark3 | MAP/microtubule affinity-regulating kinase 3 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |