Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nme3 | Rat | (+)-catechin | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of NME3 mRNA | CTD | PMID:24763279 | Nme3 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NME3 mRNA] | CTD | PMID:31150632 | Nme3 | Rat | (S)-nicotine | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Nicotine results in decreased expression of NME3 mRNA | CTD | PMID:18247414 | Nme3 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nme3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NME3 mRNA | CTD | PMID:22206623 | Nme3 | Rat | 17beta-estradiol | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of NME3 mRNA | CTD | PMID:23373633 | Nme3 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of NME3 mRNA | CTD | PMID:32145629 | Nme3 | Rat | 17beta-estradiol | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of NME3 mRNA | CTD | PMID:30165855 | Nme3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NME3 mRNA | CTD | PMID:21215274 | Nme3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NME3 mRNA | CTD | PMID:32109520 | Nme3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nme3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NME3 mRNA | CTD | PMID:21570461 | Nme3 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of NME3 mRNA | CTD | PMID:21346803 | Nme3 | Rat | 2-naphthylamine | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | 2-Naphthylamine results in decreased expression of NME3 mRNA | CTD | PMID:18247414 | Nme3 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of NME3 mRNA | CTD | PMID:25172293 | Nme3 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NME3 mRNA | CTD | PMID:28628672 | Nme3 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of NME3 mRNA | CTD | PMID:18648102 | Nme3 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Nme3 (Mus musculus) | 6480464 | bisphenol S affects the methylation of NME3 gene | CTD | PMID:31683443 | Nme3 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of NME3 mRNA | CTD | PMID:31881176 | Nme3 | Rat | afimoxifene | decreases response to substance | ISO | NME3 (Homo sapiens) | 6480464 | NME3 results in decreased susceptibility to afimoxifene | CTD | PMID:21233418 | Nme3 | Rat | aflatoxin B1 | increases methylation | ISO | NME3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of NME3 polyA tail | CTD | PMID:30157460 | Nme3 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of NME3 mRNA | CTD | PMID:16483693 | Nme3 | Rat | aristolochic acid A | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of NME3 mRNA | CTD | PMID:33212167 | Nme3 | Rat | arsenite(3-) | increases expression | ISO | Nme3 (Mus musculus) | 6480464 | arsenite results in increased expression of NME3 protein | CTD | PMID:37955338 | Nme3 | Rat | atrazine | increases expression | EXP | | 6480464 | Atrazine results in increased expression of NME3 mRNA | CTD | PMID:36841081 | Nme3 | Rat | benzo[a]pyrene | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of NME3 mRNA | CTD | PMID:18247414 | Nme3 | Rat | benzo[a]pyrene | increases methylation | ISO | NME3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NME3 promoter | CTD | PMID:27901495 | Nme3 | Rat | beta-lapachone | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of NME3 mRNA | CTD | PMID:38218311 | Nme3 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of NME3 mRNA | CTD | PMID:26496021 | Nme3 | Rat | bisphenol A | increases expression | ISO | Nme3 (Mus musculus) | 6480464 | bisphenol A results in increased expression of NME3 mRNA | CTD | PMID:38074096 | Nme3 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NME3 mRNA | CTD | PMID:30816183 more ... | Nme3 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of NME3 gene | CTD | PMID:28505145 | Nme3 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of NME3 mRNA | CTD | PMID:25181051 | Nme3 | Rat | Bisphenol B | increases expression | ISO | NME3 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of NME3 protein | CTD | PMID:34186270 | Nme3 | Rat | bisphenol F | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NME3 mRNA | CTD | PMID:28628672 | Nme3 | Rat | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of NME3 mRNA | CTD | PMID:24136188 | Nme3 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of NME3 mRNA | CTD | PMID:33453195 | Nme3 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of NME3 mRNA | CTD | PMID:25993096 | Nme3 | Rat | carbamazepine | affects expression | ISO | NME3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of NME3 mRNA | CTD | PMID:25979313 | Nme3 | Rat | carbon nanotube | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Nme3 | Rat | cisplatin | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NME3 mRNA | CTD | PMID:27392435 | Nme3 | Rat | clofibrate | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of NME3 mRNA | CTD | PMID:23811191 | Nme3 | Rat | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of NME3 mRNA | CTD | PMID:22465980 | Nme3 | Rat | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of NME3 mRNA | CTD | PMID:30556269 | Nme3 | Rat | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of NME3 mRNA | CTD | PMID:22465980 | Nme3 | Rat | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of NME3 mRNA | CTD | PMID:30556269 | Nme3 | Rat | cyclosporin A | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NME3 mRNA | CTD | PMID:20106945 | Nme3 | Rat | cyclosporin A | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Cyclosporine results in decreased expression of NME3 mRNA | CTD | PMID:19770486 | Nme3 | Rat | dexamethasone | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NME3 mRNA | CTD | PMID:28628672 | Nme3 | Rat | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of NME3 mRNA | CTD | PMID:22546817 | Nme3 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of NME3 mRNA | CTD | PMID:21266533 | Nme3 | Rat | dibutyl phthalate | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of NME3 mRNA | CTD | PMID:17361019 and PMID:21266533 | Nme3 | Rat | disodium selenite | increases expression | ISO | NME3 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of NME3 mRNA | CTD | PMID:18175754 | Nme3 | Rat | doxorubicin | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NME3 mRNA | CTD | PMID:29803840 | Nme3 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of NME3 mRNA | CTD | PMID:29391264 | Nme3 | Rat | enzyme inhibitor | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NME3 protein | CTD | PMID:23301498 | Nme3 | Rat | ethyl methanesulfonate | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of NME3 mRNA | CTD | PMID:23649840 | Nme3 | Rat | folic acid | multiple interactions | ISO | Nme3 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NME3 mRNA | CTD | PMID:22206623 | Nme3 | Rat | formaldehyde | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of NME3 mRNA | CTD | PMID:23649840 | Nme3 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of NME3 gene | CTD | PMID:22079235 | Nme3 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of NME3 mRNA | CTD | PMID:25539665 and PMID:26194646 | Nme3 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of NME3 mRNA | CTD | PMID:24136188 | Nme3 | Rat | indometacin | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NME3 mRNA | CTD | PMID:28628672 | Nme3 | Rat | indometacin | decreases expression | EXP | | 6480464 | Indomethacin results in decreased expression of NME3 mRNA | CTD | PMID:36868495 | Nme3 | Rat | methyl methanesulfonate | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of NME3 mRNA | CTD | PMID:23649840 | Nme3 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of NME3 mRNA | CTD | PMID:25566086 | Nme3 | Rat | nickel atom | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Nickel results in decreased expression of NME3 mRNA | CTD | PMID:25583101 | Nme3 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of NME3 mRNA | CTD | PMID:22110744 and PMID:22546817 | Nme3 | Rat | nicotine | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Nicotine results in decreased expression of NME3 mRNA | CTD | PMID:18247414 | Nme3 | Rat | p-menthan-3-ol | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Menthol results in decreased expression of NME3 mRNA | CTD | PMID:26760959 | Nme3 | Rat | paracetamol | affects expression | ISO | Nme3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NME3 mRNA | CTD | PMID:17562736 | Nme3 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NME3 mRNA | CTD | PMID:33387578 | Nme3 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of NME3 mRNA | CTD | PMID:32680482 | Nme3 | Rat | pirinixic acid | multiple interactions | ISO | NME3 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NME3 mRNA | CTD | PMID:19710929 | Nme3 | Rat | pirinixic acid | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of NME3 mRNA | CTD | PMID:18445702 | Nme3 | Rat | silver atom | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Silver results in decreased expression of NME3 mRNA | CTD | PMID:27131904 | Nme3 | Rat | silver(0) | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Silver results in decreased expression of NME3 mRNA | CTD | PMID:27131904 | Nme3 | Rat | sodium arsenite | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NME3 mRNA | CTD | PMID:38568856 | Nme3 | Rat | sodium fluoride | increases expression | ISO | Nme3 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of NME3 protein | CTD | PMID:28918527 | Nme3 | Rat | sunitinib | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NME3 mRNA | CTD | PMID:31533062 | Nme3 | Rat | temozolomide | increases expression | ISO | NME3 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of NME3 mRNA | CTD | PMID:31758290 | Nme3 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of NME3 mRNA | CTD | PMID:26496021 | Nme3 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NME3 mRNA] | CTD | PMID:31150632 | Nme3 | Rat | tetrachloromethane | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of NME3 mRNA | CTD | PMID:31919559 | Nme3 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NME3 mRNA | CTD | PMID:31150632 | Nme3 | Rat | thapsigargin | increases expression | ISO | NME3 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of NME3 mRNA | CTD | PMID:22378314 | Nme3 | Rat | thapsigargin | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of NME3 mRNA | CTD | PMID:29453283 | Nme3 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NME3 mRNA | CTD | PMID:16337175 more ... | Nme3 | Rat | thiram | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Thiram results in decreased expression of NME3 mRNA | CTD | PMID:38568856 | Nme3 | Rat | tolcapone | decreases expression | EXP | | 6480464 | tolcapone results in decreased expression of NME3 mRNA | CTD | PMID:24136188 | Nme3 | Rat | toluene | decreases expression | EXP | | 6480464 | Toluene results in decreased expression of NME3 mRNA | CTD | PMID:22967744 | Nme3 | Rat | urethane | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of NME3 mRNA | CTD | PMID:28818685 | Nme3 | Rat | valproic acid | increases methylation | ISO | NME3 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NME3 gene | CTD | PMID:29154799 | Nme3 | Rat | valproic acid | affects expression | ISO | Nme3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of NME3 mRNA | CTD | PMID:17292431 | Nme3 | Rat | valproic acid | decreases expression | ISO | Nme3 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of NME3 mRNA | CTD | PMID:21427059 | Nme3 | Rat | valproic acid | decreases expression | ISO | NME3 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NME3 mRNA | CTD | PMID:23179753 | Nme3 | Rat | valproic acid | affects expression | ISO | NME3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NME3 mRNA | CTD | PMID:25979313 | Nme3 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of NME3 mRNA | CTD | PMID:23034163 | |