Nme3 (NME/NM23 nucleoside diphosphate kinase 3) - Rat Genome Database

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Gene: Nme3 (NME/NM23 nucleoside diphosphate kinase 3) Rattus norvegicus
Analyze
Symbol: Nme3
Name: NME/NM23 nucleoside diphosphate kinase 3
RGD ID: 619879
Description: Predicted to enable nucleoside diphosphate kinase activity. Predicted to be involved in DNA repair; mitochondrial fusion; and nucleoside triphosphate biosynthetic process. Predicted to be located in ciliary basal body and mitochondrial outer membrane. Orthologous to human NME3 (NME/NM23 nucleoside diphosphate kinase 3); PARTICIPATES IN de novo pyrimidine biosynthetic pathway; purine metabolic pathway; pyrimidine metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: expressed in non-metastatic cells 3; expressed in non-metastatic cells 3 protein (nucleoside diphosphate kinase); expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase); NM23-dr; non-metastatic cell expressed protein 3; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,421,922 - 14,422,878 (+)NCBIGRCr8
mRatBN7.21013,917,309 - 13,918,415 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,917,403 - 13,918,359 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,664,513 - 18,665,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,153,373 - 18,154,329 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,652,590 - 13,653,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,258,232 - 14,259,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,258,380 - 14,259,336 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,074,396 - 14,075,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,145,488 - 14,146,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11014,145,487 - 14,146,444 (+)NCBI
Celera1013,596,611 - 13,597,567 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3Ratepilepsy  ISONME3 (Homo sapiens)8554872ClinVar Annotator: match by term: EpilepsyClinVarPMID:28492532
Nme3RatIdiopathic Generalized Epilepsy  ISONME3 (Homo sapiens)8554872ClinVar Annotator: match by term: Idiopathic generalized epilepsyClinVarPMID:28492532
Nme3Ratshort-rib thoracic dysplasia 9 with or without polydactyly  ISONME3 (Homo sapiens)8554872ClinVar Annotator: match by term: Saldino-Mainzer syndromeClinVarPMID:28492532
Nme3Rattuberous sclerosis 2  ISONME3 (Homo sapiens)8554872ClinVar Annotator: match by term: Tuberous sclerosis 2ClinVarPMID:16114042 more ...

1 to 20 of 97 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3Rat(+)-catechin multiple interactionsISONME3 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of NME3 mRNACTDPMID:24763279
Nme3Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NME3 mRNA]CTDPMID:31150632
Nme3Rat(S)-nicotine decreases expressionISONME3 (Homo sapiens)6480464Nicotine results in decreased expression of NME3 mRNACTDPMID:18247414
Nme3Rat1,2-dimethylhydrazine multiple interactionsISONme3 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NME3 mRNACTDPMID:22206623
Nme3Rat17beta-estradiol decreases expressionISONME3 (Homo sapiens)6480464Estradiol results in decreased expression of NME3 mRNACTDPMID:23373633
Nme3Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of NME3 mRNACTDPMID:32145629
Nme3Rat17beta-estradiol multiple interactionsISONME3 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of NME3 mRNACTDPMID:30165855
Nme3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NME3 mRNACTDPMID:21215274
Nme3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NME3 mRNACTDPMID:32109520
Nme3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISONme3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of NME3 mRNACTDPMID:21570461
Nme3Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of NME3 mRNACTDPMID:21346803
Nme3Rat2-naphthylamine decreases expressionISONME3 (Homo sapiens)64804642-Naphthylamine results in decreased expression of NME3 mRNACTDPMID:18247414
Nme3Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISONme3 (Mus musculus)6480464tetrabromobisphenol A results in decreased expression of NME3 mRNACTDPMID:25172293
Nme3Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISONME3 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of NME3 mRNACTDPMID:28628672
Nme3Rat4,4'-diaminodiphenylmethane decreases expressionISONme3 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in decreased expression of NME3 mRNACTDPMID:18648102
Nme3Rat4,4'-sulfonyldiphenol affects methylationISONme3 (Mus musculus)6480464bisphenol S affects the methylation of NME3 geneCTDPMID:31683443
Nme3Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of NME3 mRNACTDPMID:31881176
Nme3Ratafimoxifene decreases response to substanceISONME3 (Homo sapiens)6480464NME3 results in decreased susceptibility to afimoxifeneCTDPMID:21233418
Nme3Rataflatoxin B1 increases methylationISONME3 (Homo sapiens)6480464Aflatoxin B1 results in increased methylation of NME3 polyA tailCTDPMID:30157460
Nme3Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of NME3 mRNACTDPMID:16483693

1 to 20 of 97 rows

Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3Ratbiological_process  ND 159840712/2008: no relevant rat dataRGD 
Nme3RatCTP biosynthetic process involved_inIEAInterPro:IPR0015641600115GO_REF:0000002InterProGO_REF:0000002
Nme3RatDNA repair involved_inISONME3 (Homo sapiens)1624291 PMID:26945015RGDPMID:26945015
Nme3RatDNA repair involved_inIEAUniProtKB:Q13232 and ensembl:ENSP000002193021600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3RatGTP biosynthetic process involved_inIEAInterPro:IPR0015641600115GO_REF:0000002InterProGO_REF:0000002
Nme3Ratmitochondrial fusion involved_inISONME3 (Homo sapiens)1624291 PMID:30587587RGDPMID:30587587
Nme3Ratmitochondrial fusion involved_inIEAUniProtKB:Q13232 and ensembl:ENSP000002193021600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3Ratnucleoside triphosphate biosynthetic process involved_inISONME3 (Homo sapiens)1624291 PMID:30587587RGDPMID:30587587
Nme3Ratnucleoside triphosphate biosynthetic process involved_inIEAUniProtKB:Q13232 and ensembl:ENSP000002193021600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3RatUTP biosynthetic process involved_inIEAInterPro:IPR0015641600115GO_REF:0000002InterProGO_REF:0000002
1 to 10 of 10 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3Ratciliary basal body located_inISONme3 (Mus musculus)1624291 PMID:30111592RGDPMID:30111592
Nme3Ratciliary basal body located_inIEAUniProtKB:Q9WV85 and ensembl:ENSMUSP000000249781600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3Ratcytoplasm located_inISONME3 (Homo sapiens)1624291 PMID:26945015RGDPMID:26945015
Nme3Ratcytoplasm located_inIEAUniProtKB:Q13232 and ensembl:ENSP000002193021600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3Ratmitochondrial outer membrane located_inISONME3 (Homo sapiens)1624291 PMID:30587587RGDPMID:30587587
Nme3Ratmitochondrial outer membrane located_inIEAUniProtKB:Q13232 and ensembl:ENSP000002193021600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3Ratmitochondrion located_inISONME3 (Homo sapiens)9068941 PMID:34800366FlyBasePMID:34800366

Molecular Function
1 to 11 of 11 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Nme3Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Nme3Ratnucleoside diphosphate kinase activity enablesISONME3 (Homo sapiens)1624291 PMID:30587587RGDPMID:30587587
Nme3Ratnucleoside diphosphate kinase activity enablesIEAUniProtKB:Q13232 and ensembl:ENSP000002193021600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3Ratnucleoside diphosphate kinase activity enablesIEAEC:2.7.4.61600115GO_REF:0000003UniProtGO_REF:0000003
Nme3Ratnucleoside diphosphate kinase activity enablesIEAUniProtKB:Q9WV85 and ensembl:ENSMUSP000000249781600115GO_REF:0000107EnsemblGO_REF:0000107
Nme3Ratnucleoside diphosphate kinase activity enablesISONme3 (Mus musculus)1624291 PMID:22438820RGDPMID:22438820
Nme3Ratnucleoside diphosphate kinase activity enablesIEAInterPro:IPR0015641600115GO_REF:0000002InterProGO_REF:0000002
Nme3Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Nme3Ratprotein binding enablesISONME3 (Homo sapiens)1624291UniProtKB:O43765 more ...RGDPMID:16169070 more ...
Nme3Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 11 of 11 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3Ratde novo pyrimidine biosynthetic pathway   ISONME3 (Homo sapiens)5134680 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Nme3Ratpurine metabolic pathway  IEA 6907045 KEGGrno:00230
Nme3Ratpyrimidine metabolic pathway  IEA 6907045 KEGGrno:00240

1 to 13 of 13 rows
#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. The human Nm23/nucleoside diphosphate kinases. Lacombe ML, etal., J Bioenerg Biomembr. 2000 Jun;32(3):247-58.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis. Negroni A, etal., Cell Death Differ 2000 Sep;7(9):843-50.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Information Derived from GenBank Report RGD, Sept. 2003
1 to 13 of 13 rows
PMID:18614015   PMID:23376485   PMID:34800366  



Nme3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,421,922 - 14,422,878 (+)NCBIGRCr8
mRatBN7.21013,917,309 - 13,918,415 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,917,403 - 13,918,359 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,664,513 - 18,665,469 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01018,153,373 - 18,154,329 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,652,590 - 13,653,546 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,258,232 - 14,259,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,258,380 - 14,259,336 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01014,074,396 - 14,075,352 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,145,488 - 14,146,444 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11014,145,487 - 14,146,444 (+)NCBI
Celera1013,596,611 - 13,597,567 (+)NCBICelera
Cytogenetic Map10q12NCBI
NME3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,770,320 - 1,771,543 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,770,320 - 1,771,561 (-)EnsemblGRCh38hg38GRCh38
GRCh37161,820,321 - 1,821,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,760,322 - 1,761,711 (-)NCBINCBI36Build 36hg18NCBI36
Build 34161,760,322 - 1,761,711NCBI
Celera162,032,596 - 2,033,985 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,743,213 - 1,744,602 (-)NCBIHuRef
CHM1_1161,820,269 - 1,821,658 (-)NCBICHM1_1
T2T-CHM13v2.0161,786,150 - 1,787,373 (-)NCBIT2T-CHM13v2.0
Nme3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,115,474 - 25,116,505 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1725,115,474 - 25,116,496 (+)EnsemblGRCm39 Ensembl
GRCm381724,896,500 - 24,897,531 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,896,500 - 24,897,522 (+)EnsemblGRCm38mm10GRCm38
MGSCv371725,033,445 - 25,034,476 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,624,106 - 24,625,103 (+)NCBIMGSCv36mm8
Celera1725,423,190 - 25,424,231 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Nme3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,497,779 - 15,498,873 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,497,779 - 15,498,873 (+)NCBIChiLan1.0ChiLan1.0
NME3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,036,976 - 2,038,428 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,818,421 - 5,819,857 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016392,694 - 394,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1161,822,719 - 1,824,160 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,822,719 - 1,824,147 (-)Ensemblpanpan1.1panPan2
NME3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,131,807 - 39,132,756 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,370,445 - 40,371,394 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,447,987 - 39,448,936 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1639,124,673 - 39,125,622 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0639,097,254 - 39,098,202 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,575,702 - 39,576,651 (+)NCBIUU_Cfam_GSD_1.0
Nme3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,486,486 - 104,487,636 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,221,915 - 2,222,814 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,222,055 - 2,222,977 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NME3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,195,635 - 40,196,869 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,195,456 - 40,197,121 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,659,552 - 41,661,739 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NME3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,679,361 - 1,680,796 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,679,549 - 1,680,547 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,405,487 - 29,406,892 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nme3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913480,190 - 481,023 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913479,893 - 481,023 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Nme3
4 total Variants

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:82
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000021650
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129497586Rat

1 to 10 of 25 rows
AV001970  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,916,911 - 13,917,007 (+)MAPPERmRatBN7.2
Rnor_6.01014,257,889 - 14,257,984NCBIRnor6.0
Rnor_5.01014,073,905 - 14,074,000UniSTSRnor5.0
RGSC_v3.41014,144,997 - 14,145,092UniSTSRGSC3.4
Celera1013,596,120 - 13,596,215UniSTS
Cytogenetic Map10q12UniSTS
AI575323  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,918,169 - 13,918,366 (+)MAPPERmRatBN7.2
Rnor_6.01014,259,147 - 14,259,343NCBIRnor6.0
Rnor_5.01014,075,163 - 14,075,359UniSTSRnor5.0
RGSC_v3.41014,146,255 - 14,146,451UniSTSRGSC3.4
Celera1013,597,378 - 13,597,574UniSTS
RH 3.4 Map10171.0UniSTS
Cytogenetic Map10q12UniSTS
RH129468  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,916,916 - 13,917,102 (+)MAPPERmRatBN7.2
Rnor_6.01014,257,894 - 14,258,079NCBIRnor6.0
Rnor_5.01014,073,910 - 14,074,095UniSTSRnor5.0
RGSC_v3.41014,145,002 - 14,145,187UniSTSRGSC3.4
Celera1013,596,125 - 13,596,310UniSTS
Cytogenetic Map10q12UniSTS
RH143979  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,918,499 - 13,918,599 (+)MAPPERmRatBN7.2
Rnor_6.01014,259,477 - 14,259,576NCBIRnor6.0
Rnor_5.01014,075,493 - 14,075,592UniSTSRnor5.0
RGSC_v3.41014,146,585 - 14,146,684UniSTSRGSC3.4
Celera1013,597,708 - 13,597,807UniSTS
RH 3.4 Map10174.1UniSTS
Cytogenetic Map10q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000021650   ⟹   ENSRNOP00000021650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,917,403 - 13,918,359 (+)Ensembl
Rnor_6.0 Ensembl1014,258,380 - 14,259,336 (+)Ensembl
RefSeq Acc Id: NM_053507   ⟹   NP_445959
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81014,421,922 - 14,422,878 (+)NCBI
mRatBN7.21013,917,403 - 13,918,359 (+)NCBI
Rnor_6.01014,258,380 - 14,259,336 (+)NCBI
Rnor_5.01014,074,396 - 14,075,352 (+)NCBI
RGSC_v3.41014,145,488 - 14,146,444 (+)RGD
Celera1013,596,611 - 13,597,567 (+)RGD
Sequence:
Protein RefSeqs NP_445959 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG54075 (Get FASTA)   NCBI Sequence Viewer  
  EDM03891 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021650
  ENSRNOP00000021650.1
RefSeq Acc Id: NP_445959   ⟸   NM_053507
- Peptide Label: precursor
- UniProtKB: Q99NI1 (UniProtKB/TrEMBL),   G3V816 (UniProtKB/TrEMBL),   A6HCY6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021650   ⟸   ENSRNOT00000021650
Nucleoside diphosphate kinase-like

Name Modeler Protein Id AA Range Protein Structure
AF-G3V816-F1-model_v2 AlphaFold G3V816 1-169 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697037
Promoter ID:EPDNEW_R7560
Type:initiation region
Name:Nme3_1
Description:NME/NM23 nucleoside diphosphate kinase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01014,258,371 - 14,258,431EPDNEW


1 to 40 of 40 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-25813 BioCyc
BioCyc Pathway PWY-7176 [UTP and CTP de novo biosynthesis] BioCyc
  PWY-7184 [pyrimidine deoxyribonucleotides de novo biosynthesis I] BioCyc
  PWY-7197 [pyrimidine deoxyribonucleotide phosphorylation] BioCyc
  PWY-7205 [CMP phosphorylation] BioCyc
  PWY-7210 [pyrimidine deoxyribonucleotides biosynthesis from CTP] BioCyc
  PWY-7221 [guanosine ribonucleotides de novo biosynthesis] BioCyc
  PWY-7224 [purine deoxyribonucleosides salvage] BioCyc
  PWY-7226 [guanosine deoxyribonucleotides de novo biosynthesis I] BioCyc
  PWY-7227 [adenosine deoxyribonucleotides de novo biosynthesis I] BioCyc
BioCyc Pathway Image PWY-7176 BioCyc
  PWY-7184 BioCyc
  PWY-7197 BioCyc
  PWY-7205 BioCyc
  PWY-7210 BioCyc
  PWY-7221 BioCyc
  PWY-7224 BioCyc
  PWY-7226 BioCyc
  PWY-7227 BioCyc
Ensembl Genes ENSRNOG00000015749 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021650 ENTREZGENE
  ENSRNOT00000021650.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.141 UniProtKB/TrEMBL
InterPro NDK-like_dom UniProtKB/TrEMBL
  NDK-like_dom_sf UniProtKB/TrEMBL
  Nucleoside_diP_kinase UniProtKB/TrEMBL
  Nucleoside_diP_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:85269 UniProtKB/TrEMBL
NCBI Gene 85269 ENTREZGENE
PANTHER NUCLEOSIDE DIPHOSPHATE KINASE UniProtKB/TrEMBL
Pfam NDK UniProtKB/TrEMBL
PhenoGen Nme3 PhenoGen
PRINTS NUCDPKINASE UniProtKB/TrEMBL
PROSITE NDP_KINASES UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015749 RatGTEx
SMART NDK UniProtKB/TrEMBL
Superfamily-SCOP SSF54919 UniProtKB/TrEMBL
UniProt A6HCY6 ENTREZGENE, UniProtKB/TrEMBL
  G3V816 ENTREZGENE, UniProtKB/TrEMBL
  Q99NI1 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 40 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-05 Nme3  NME/NM23 nucleoside diphosphate kinase 3  Nme3  non-metastatic cells 3, protein expressed in  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-14 Nme3  non-metastatic cells 3, protein expressed in  Nme3  expressed in non-metastatic cells 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Nme3  expressed in non-metastatic cells 3  Nme3  non-metastatic cell expressed protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Nme3  non-metastatic cell expressed protein 3    non-metastatic cells 3, protein expressed in  Name updated 1299863 APPROVED
2005-01-20 Nme3  non-metastatic cells 3, protein expressed in    expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase)  Name updated 1299863 APPROVED
2002-08-07 Nme3  expressed in non-metastatic cells 3, protein (nucleoside diphosphate kinase)      Symbol and Name status set to provisional 70820 PROVISIONAL