Slc23a1 (solute carrier family 23 member 1)

Gene: Slc23a1 (solute carrier family 23 member 1) Rattus norvegicus

Analyze

Symbol:

Slc23a1

Name:

solute carrier family 23 member 1

RGD ID:

619875

Description:

Enables L-ascorbate:sodium symporter activity and L-ascorbic acid transmembrane transporter activity. Involved in L-ascorbic acid transmembrane transport. Located in basal plasma membrane; brush border; and cytoplasm. Orthologous to human SLC23A1 (solute carrier family 23 member 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

na(+)/L-ascorbic acid transporter 1; sodium-coupled ascorbic acid transporter 1; sodium-coupled ascorbic acid transporter 1; sodium-dependent vitamin C transporter 1; solute carrier family 23 (ascorbic acid transporter), member 1; solute carrier family 23 (nucleobase transporters), member 1; SVCT1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SLC23A1 (solute carrier family 23 member 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, Panther, PhylomeDB
Mus musculus (house mouse):	Slc23a1 (solute carrier family 23 (nucleobase transporters), member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Slc23a1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SLC23A1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SLC23A1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Slc23a1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SLC23A1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SLC23A1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Slc23a1 (solute carrier family 23 member 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC23A2 (solute carrier family 23 member 2)	HGNC	OrthoDB
Homo sapiens (human):	TNFSF11 (TNF superfamily member 11)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Slc23a1 (solute carrier family 23 (nucleobase transporters), member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SLC23A1 (solute carrier family 23 member 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	slc23a1 (solute carrier family 23 member 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C51E3.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6293	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	R11E3.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	T07G12.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	T07G12.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T07G12.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y59E9AL.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	slc23a1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	27,490,549 - 27,504,563 (-)	NCBI		GRCr8
mRatBN7.2	18	27,214,940 - 27,230,564 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	27,216,281 - 27,230,697 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	27,343,879 - 27,355,815 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	28,106,018 - 28,117,920 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	27,440,904 - 27,452,806 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	28,413,910 - 28,428,133 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	28,414,009 - 28,428,117 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	28,127,118 - 28,141,110 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	28,238,953 - 28,250,889 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	28,265,423 - 28,277,535 (-)	NCBI
Celera	18	26,950,004 - 26,961,940 (-)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant intellectual developmental disorder 31 (ISO)

cholestasis (ISO)

Experimental Liver Cirrhosis (ISO)

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Intracranial Hemorrhages (ISO)

Neurodevelopmental Disorders (ISO)

respiratory failure (ISO)

STING-associated vasculopathy with onset in infancy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,1-dichloroethene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-methylcholanthrene (EXP)

4,4'-diaminodiphenylmethane (EXP)

4-hydroxyphenyl retinamide (ISO)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

amiodarone (EXP)

ammonium chloride (EXP)

benzbromarone (EXP)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bilirubin IXalpha (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

clofibrate (EXP)

cobalt dichloride (EXP)

cocaine (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

cyproconazole (ISO)

diclofenac (ISO)

dioxygen (ISO)

epoxiconazole (ISO)

flutamide (EXP)

inulin (ISO)

L-ascorbic acid (ISO)

L-ethionine (EXP)

methapyrilene (ISO)

N-nitrosodimethylamine (EXP)

O-methyleugenol (ISO)

omeprazole (EXP)

ozone (ISO)

paracetamol (ISO)

pentanal (ISO)

pentane-2,3-dione (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (EXP,ISO)

pravastatin (EXP,ISO)

progesterone (ISO)

propanal (ISO)

propiconazole (ISO)

quercetin (ISO)

rotenone (EXP)

silicon dioxide (ISO)

taurocholic acid (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (EXP)

Triptolide (EXP)

trovafloxacin (ISO)

tunicamycin (ISO)

ursodeoxycholic acid (ISO)

valproic acid (ISO)

vanadium atom (ISO)

vanadium(0) (ISO)

zaragozic acid A (EXP,ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

brain development (IEA,ISO,ISS)

dehydroascorbic acid transport (IEA,ISO,ISS)

L-ascorbic acid transmembrane transport (IDA,IEA,ISO)

lung development (IEA,ISO)

response to toxic substance (IEA,ISO,ISS)

sodium ion transmembrane transport (IEA)

sodium ion transport (ISO,ISS)

urate transport (IEA)

Cellular Component

apical plasma membrane (IEA,ISO,ISS)

basal plasma membrane (IDA,IEA,ISO)

brush border (IDA)

cytoplasm (IDA,IEA,ISO)

intracellular organelle (IEA,ISO,ISS)

plasma membrane (ISO)

Molecular Function

dehydroascorbic acid transmembrane transporter activity (IEA,ISO,ISS)

L-ascorbate:sodium symporter activity (IDA,IEA,ISO,ISS)

L-ascorbic acid transmembrane transporter activity (IDA,IEA,ISO)

protein binding (ISO)

sodium ion transmembrane transporter activity (ISO,ISS)

urate transmembrane transporter activity (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular identification and functional characterization of the vitamin C transporters expressed by Sertoli cells.	Angulo C, etal., J Cell Physiol. 2008 Dec;217(3):708-16. doi: 10.1002/jcp.21545.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Immunohistochemical localization of sodium-dependent L-ascorbic acid transporter 1 protein in rat kidney.	Lee JH, etal., Histochem Cell Biol. 2006 Oct;126(4):491-4. Epub 2006 May 4.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Flavonoid inhibition of sodium-dependent vitamin C transporter 1 (SVCT1) and glucose transporter isoform 2 (GLUT2), intestinal transporters for vitamin C and Glucose.	Song J, etal., J Biol Chem 2002 May 3;277(18):15252-60.
10.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
11.	A family of mammalian Na+-dependent L-ascorbic acid transporters.	Tsukaguchi H, etal., Nature 1999 May 6;399(6731):70-5.

Additional References at PubMed

PMID:10631088	PMID:11895172	PMID:11984597	PMID:12559983	PMID:15333707	PMID:15489334	PMID:15993839	PMID:17575980	PMID:18094143	PMID:18247577	PMID:18417304	PMID:19056867
PMID:19216494	PMID:21733302	PMID:22348976	PMID:23708151

Genomics

Comparative Map Data

Slc23a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	27,490,549 - 27,504,563 (-)	NCBI		GRCr8
mRatBN7.2	18	27,214,940 - 27,230,564 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	27,216,281 - 27,230,697 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	27,343,879 - 27,355,815 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	28,106,018 - 28,117,920 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	27,440,904 - 27,452,806 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	28,413,910 - 28,428,133 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	28,414,009 - 28,428,117 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	28,127,118 - 28,141,110 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	28,238,953 - 28,250,889 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	28,265,423 - 28,277,535 (-)	NCBI
Celera	18	26,950,004 - 26,961,940 (-)	NCBI		Celera
Cytogenetic Map	18	p11	NCBI

SLC23A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	139,367,196 - 139,385,676 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	139,367,196 - 139,384,553 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	138,702,885 - 138,718,986 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	138,730,787 - 138,746,900 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	138,730,787 - 138,746,900	NCBI
Celera	5	134,824,593 - 134,840,618 (-)	NCBI		Celera
Cytogenetic Map	5	q31.2	NCBI
HuRef	5	133,892,618 - 133,908,788 (-)	NCBI		HuRef
CHM1_1	5	138,135,498 - 138,151,676 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	139,893,271 - 139,911,881 (-)	NCBI		T2T-CHM13v2.0

Slc23a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	35,747,657 - 35,762,900 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	35,747,657 - 35,760,297 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	35,604,224 - 35,629,845 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	35,614,604 - 35,627,244 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	35,774,258 - 35,786,881 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	35,740,578 - 35,753,192 (-)	NCBI		MGSCv36	mm8
MGSCv36	18	35,794,115 - 35,806,597 (-)	NCBI		MGSCv36	mm8
Celera	18	36,070,745 - 36,083,392 (-)	NCBI		Celera
Cytogenetic Map	18	B2	NCBI
cM Map	18	19.17	NCBI

Slc23a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955418	1,176,000 - 1,186,940 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955418	1,176,390 - 1,192,270 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC23A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	134,638,723 - 134,649,462 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	132,775,959 - 132,789,014 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	134,737,344 - 134,756,153 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	140,859,975 - 140,877,214 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	140,859,984 - 140,877,214 (-)	Ensembl	panpan1.1		panPan2

SLC23A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	34,694,064 - 34,708,498 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	34,698,838 - 34,708,412 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	31,801,133 - 31,809,319 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	35,148,002 - 35,162,589 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	35,152,908 - 35,162,973 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	32,205,366 - 32,213,552 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	33,071,664 - 33,079,850 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	33,823,283 - 33,831,469 (-)	NCBI		UU_Cfam_GSD_1.0

Slc23a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	153,138,372 - 153,159,132 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936531	8,457,957 - 8,471,258 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936531	8,457,779 - 8,471,244 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC23A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	141,258,323 - 141,276,442 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	141,258,318 - 141,277,555 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	147,081,831 - 147,107,402 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC23A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	42,040,163 - 42,056,593 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	42,044,590 - 42,055,831 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	35,832,046 - 35,861,341 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc23a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624743	32,174,922 - 32,186,697 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624743	32,169,051 - 32,186,618 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc23a1
56 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	62
Count of miRNA genes:	54
Interacting mature miRNAs:	60
Transcripts:	ENSRNOT00000027048
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11941791	31393320	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	11941791	31393320	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944299	31359530	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	18234564	31359530	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	18234564	31359530	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	22066242	52293055	Rat
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25570985	70570985	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26548082	46969551	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26548082	46969551	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26548082	46969551	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26548082	46969551	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26548082	46969551	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26548082	46969551	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26548082	46969551	Rat

Markers in Region

RH129257

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	27,218,120 - 27,218,272 (+)	MAPPER	mRatBN7.2
mRatBN7.2	1	179,078,689 - 179,078,953 (-)	MAPPER	mRatBN7.2
Rnor_6.0	1	193,699,300 - 193,699,584	NCBI	Rnor6.0
Rnor_6.0	18	28,415,673 - 28,415,824	NCBI	Rnor6.0
Rnor_5.0	18	28,128,783 - 28,128,934	UniSTS	Rnor5.0
Rnor_5.0	1	200,756,118 - 200,756,402	UniSTS	Rnor5.0
RGSC_v3.4	1	183,456,241 - 183,457,302	UniSTS	RGSC3.4
RGSC_v3.4	18	28,240,618 - 28,240,769	UniSTS	RGSC3.4
Celera	18	26,951,669 - 26,951,820	UniSTS
Celera	1	176,757,650 - 176,757,801	UniSTS
Cytogenetic Map	18	p11	UniSTS

RH137333

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	27,216,660 - 27,216,844 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	28,414,213 - 28,414,396	NCBI	Rnor6.0
Rnor_5.0	18	28,127,323 - 28,127,506	UniSTS	Rnor5.0
RGSC_v3.4	18	28,239,158 - 28,239,341	UniSTS	RGSC3.4
Celera	18	26,950,209 - 26,950,392	UniSTS
Cytogenetic Map	18	p11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		25	25		25				29	3
Low	2	7	32	16	19	16	4	4	11	6	21	11	4
Below cutoff		8					4	7	12		13		4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_017315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC135285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF080452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078851	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ219321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000078202 ⟹ ENSRNOP00000073343

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	18	28,418,191 - 28,428,117 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000084372 ⟹ ENSRNOP00000072205

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	27,216,281 - 27,230,697 (-)	Ensembl
Rnor_6.0 Ensembl	18	28,414,009 - 28,425,944 (-)	Ensembl

RefSeq Acc Id:

NM_017315 ⟹ NP_059011

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	27,490,549 - 27,502,485 (-)	NCBI
mRatBN7.2	18	27,216,456 - 27,228,397 (-)	NCBI
Rnor_6.0	18	28,414,008 - 28,425,944 (-)	NCBI
Rnor_5.0	18	28,127,118 - 28,141,110 (-)	NCBI
RGSC_v3.4	18	28,238,953 - 28,250,889 (-)	RGD
Celera	18	26,950,004 - 26,961,940 (-)	RGD

Sequence:

show sequence

CAGAGATGAAAGCTCAGGAGGACCCCGGGAGCTCAAAGCAGCATGAATGCCCAGATTCAGCAGG
GACTTCCACCAGGGACCAGCAGGCACCTTTGCCCGCGGAGCCCAAGTTTGACATGTTGTACAAG
ATTGAGGACGTGCCACCATGGTACCTGTGTATCCTGCTGGGCTTCCAGCATTACCTGACATGCT
TCAGTGGTACCATTGCTGTGCCCTTCCTCCTGGCTGAGGCGCTGTGTGTGGGCCGCGACCAGCA
CATGATCAGTCAGCTCATTGGTACCATCTTCACCTGCGTGGGTATCACCACTCTCATTCAGACT
ACAGTGGGCATCCGGCTGCCGCTGTTCCAGGCCAGTGCCTTTGCGTTTCTGGTTCCAGCCAAGG
CTATCCTGGCCTTGGAGAGGTGGAAGTGTCCTCCAGAAGAGGAGATCTACGGTAACTGGAGTAT
GCCCCTGAACACCTCTCATATCTGGCATCCTCGGATTCGGGAGGTCCAGGGTGCAATCATGGTG
TCCAGCGTGGTAGAGGTGGTGATTGGGCTGTTGGGGCTGCCTGGGGCCCTGCTCAGCTACATTG
GACCTCTCACAGTCACCCCCACTGTCTCCCTTATCGGTCTCTCTGTTTTCCAAGCTGCTGGCGA
CCGAGCTGGCTCCCATTGGGGCATTTCGGCTTGCTCCATTCTACTGATCGTCCTGTTCTCCCAG
TATCTACGCAACCTCACCTTCCTGTTGCCTGTTTACCGATGGGGCAAGGGTCTTACTCTCTTCC
GCATCCAGATCTTTAAGATGTTTCCGATCGTGCTGGCCATCATGACCGTGTGGCTACTCTGCTA
TGTGCTGACTCTGACAGACGTGCTGCCCGCAGATCCCACAGTCTACGGTTTCCAGGCTCGAACT
GATGCCCGAGGGGACATCATGGCTATCTCTCCCTGGATCCGGATCCCCTACCCATGTCAATGGG
GCCTACCCACAGTGACCGTGGCTGCAGTTCTGGGAATGTTCAGCGCCACACTGGCGGGCATCAT
CGAGTCCATCGGTGATTACTATGCCTGCGCCCGGTTGGCTGGAGCACCACCCCCTCCAGTCCAT
GCTATCAACAGGGGGATTTTCACCGAAGGCGTCTGCTGCATCATCGCTGGGCTACTGGGCACAG
GCAACGGGTCCACCTCTTCCAGCCCCAACATCGGGGTCCTAGGGATTACCAAGGTGGGCAGCCG
AAGAGTCGTGCAGTATGGTGCAGGTATCATGCTAATCCTGGGGGCCATTGGCAAATTCACAGCT
CTCTTCGCCTCACTGCCGGACCCCATCCTGGGAGGGATGTTCTGCACTCTTTTCGGTATGATCA
CCGCTGTGGGACTGTCCAATCTGCAGTTTGTGGACATGAACTCCTCCCGCAACCTCTTTGTATT
GGGATTCTCCATGTTCTTCGGCCTCACGCTACCCAACTACCTGGATTCCAACCCAGGTGCCATC
AACACAGGCGTTCCTGAAGTGGATCAGATCCTAACTGTGCTGCTGACCACAGAGATGTTTGTTG
GTGGCTGTCTTGCTTTCATACTGGACAACACAGTACCAGGGAGCCCAGAGGAAAGAGGTCTGAT
ACAGTGGAAAGCCGGGGCACACGCCAACAGTGAGACGCTGGCCAGTCTCAAGAGCTACGATTTC
CCGTTCGGGATGGGCATGGTAAAAAGGACCACCTTTTTTAGATACATCCCCATCTGCCCAGTCT
TCAGAGGATTCTCTAAGACAGAAAATCAGCCTGCAGTTCTAGAAGACGCTCCAGACAACACAGA
AACTGGGTCTGTGTGTACCAAGGTCTGAAACTACCTCTATGAAAGGAGGCACGGTGTGTATCAG
GAAAACAAACTACCCAGGAGACAGAAGACCTGAGTTGGAGATCTCAGCTGTCCCTATTCTAAAT
TCCCATGGAAGACTGGACAGATCACCCTCTCTTTGACTCCATTTTCGTGACAGCCCAAGTCTCT
AAGTCCTCGGGAGACCTGTATTTGCACTGCTCTGATTCCTTACTTCCACTTTCCTAAGCATGCA
TGTCAAGGAGGAAGAGCTGGAGAAAAAAAAGGAAACCCAGAGAGATTCTAGGGCTTCATGTAGA
CATGAAGATAGGGTTAAAAACAAACCAAACAAAACCCCCTGAATTCCAATGCTATGTATTTTAA
GACCAAAACAGTATTAAATAATATACTGGACCAATAATTTAGATAAGTTTAGATAAGTATTCTC
CCTTCACACAGGGAAAATAAATCTATACTTTCAGACTAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAA

hide sequence

RefSeq Acc Id:

XM_006254602 ⟹ XP_006254664

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	27,490,549 - 27,504,563 (-)	NCBI
mRatBN7.2	18	27,214,940 - 27,230,564 (-)	NCBI
Rnor_6.0	18	28,413,910 - 28,428,133 (-)	NCBI
Rnor_5.0	18	28,127,118 - 28,141,110 (-)	NCBI

Sequence:

show sequence

AGCTGCGATTGAAGAAGGGGGAGAAGGGGCTCCCTATCTGCCACCCGCAGAGAGCTGGGAGGAG
TTGCAGAGGCCCAACAGGTCAAACCACTTCGAGAGGGCAGTGCAGGAACCAGGAGAGGAGTGGA
CCAAAAAGCAGAGGAAAGGCTGGAGCTGCAAAGGGAACAGCACTCAAGACGGCCATGAAGCAGC
TGCCTAGCTGGAAAGCCATGCTGCCCGTGGGCCCTTGGCTTAGCCTGTGCCCCTGTGCCCCAGA
CGGGACACGGGCGCAGCAACTCAGAATGAAAGAGTTAACACATGCAGCCCCAGAGGGTAGATGT
GACAGCGCATATACAAATACAGAGATTTCTCAAACCCGTGTCTCAGAGATGAAAGCTCAGGAGG
ACCCCGGGAGCTCAAAGCAGCATGAATGCCCAGATTCAGCAGGGACTTCCACCAGGGACCAGCA
GGCACCTTTGCCCGCGGAGCCCAAGTTTGACATGTTGTACAAGATTGAGGACGTGCCACCATGG
TACCTGTGTATCCTGCTGGGCTTCCAGCATTACCTGACATGCTTCAGTGGTACCATTGCTGTGC
CCTTCCTCCTGGCTGAGGCGCTGTGTGTGGGCCGCGACCAGCACATGATCAGTCAGCTCATTGG
TACCATCTTCACCTGCGTGGGTATCACCACTCTCATTCAGACTACAGTGGGCATCCGGCTGCCG
CTGTTCCAGGCCAGTGCCTTTGCGTTTCTGGTTCCAGCCAAGGCTATCCTGGCCTTGGAGAGGT
GGAAGTGTCCTCCAGAAGAGGAGATCTACGGTAACTGGAGTATGCCCCTGAACACCTCTCATAT
CTGGCATCCTCGGATTCGGGAGGTCCAGGGTGCAATCATGGTGTCCAGCGTGGTAGAGGTGGTG
ATTGGGCTGTTGGGGCTGCCTGGGGCCCTGCTCAGCTACATTGGACCTCTCACAGTCACCCCCA
CTGTCTCCCTTATCGGTCTCTCTGTTTTCCAAGCTGCTGGCGACCGAGCTGGCTCCCATTGGGG
CATTTCGGCTTGCTCCATTCTACTGATCGTCCTGTTCTCCCAGTATCTACGCAACCTCACCTTC
CTGTTGCCTGTTTACCGATGGGGCAAGGGTCTTACTCTCTTCCGCATCCAGATCTTTAAGATGT
TTCCGATCGTGCTGGCCATCATGACCGTGTGGCTACTCTGCTATGTGCTGACTCTGACAGACGT
GCTGCCCGCAGATCCCACAGTCTACGGTTTCCAGGCTCGAACTGATGCCCGAGGGGACATCATG
GCTATCTCTCCCTGGATCCGGATCCCCTACCCATGTCAATGGGGCCTACCCACAGTGACCGTGG
CTGCAGTTCTGGGAATGTTCAGCGCCACACTGGCGGGCATCATCGAGTCCATCGGTGATTACTA
TGCCTGCGCCCGGTTGGCTGGAGCACCACCCCCTCCAGTCCATGCTATCAACAGGGGGATTTTC
ACCGAAGGCGTCTGCTGCATCATCGCTGGGCTACTGGGCACAGGCAACGGGTCCACCTCTTCCA
GCCCCAACATCGGGGTCCTAGGGATTACCAAGGTGGGCAGCCGAAGAGTCGTGCAGTATGGTGC
AGGTATCATGCTAATCCTGGGGGCCATTGGCAAATTCACAGCTCTCTTCGCCTCACTGCCGGAC
CCCATCCTGGGAGGGATGTTCTGCACTCTTTTCGGTATGATCACCGCTGTGGGACTGTCCAATC
TGCAGTTTGTGGACATGAACTCCTCCCGCAACCTCTTTGTATTGGGATTCTCCATGTTCTTCGG
CCTCACGCTACCCAACTACCTGGATTCCAACCCAGGTGCCATCAACACAGGCGTTCCTGAAGTG
GATCAGATCCTAACTGTGCTGCTGACCACAGAGATGTTTGTTGGTGGCTGTCTTGCTTTCATAC
TGGACAACACAGTACCAGGGAGCCCAGAGGAAAGAGGTCTGATACAGTGGAAAGCCGGGGCACA
CGCCAACAGTGAGACGCTGGCCAGTCTCAAGAGCTACGATTTCCCGTTCGGGATGGGCATGGTA
AAAAGGACCACCTTTTTTAGATACATCCCCATCTGCCCAGTCTTCAGAGGATTCTCTAAGACAG
AAAATCAGCCTGCAGTTCTAGAAGACGCTCCAGACAACACAGAAACTGGGTCTGTGTGTACCAA
GGTCTGAAACTACCTCTATGAAAGGAGGCACGGTGTGTATCAGGAAAACAAACTACCCAGGAGA
CAGAAGACCTGAGTTGGAGATCTCAGCTGTCCCTATTCTAAATTCCCATGGAAGACTGGACAGA
TCACCCTCTCTTTGACTCCATTTTCGTGACAGCCCAAGTCTCTAAGTCCTCGGGAGACCTGTAT
TTGCACTGCTCTGATTCCTTACTTCCACTTTCCTAAGCATGCATGTCAAGGAGGAAGAGCTGGA
GAAAAAAAAGGAAACCCAGAGAGATTCTAGGGCTTCATGTAGACATGAAGATAGGGTTAAAAAC
AAACCAAACAAAACCCCCTGAATTCCAATGCTATGTATTTTAAGACCAAAACAGTATTAAATAA
TATACTGGACCAATAATTTAGATAAGTTTAGATAAGTATTCTCCCTTCACACAGGGAAAATAAA
TCTATACTTTCAGACTAGCTCAGTGATAAAGATGTCTATTTAGAATGTTCCAGAACTGGGCTTG
ACCTTCAACATTAAATATACAGAAATAAAAACCCTTAAGAGGAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_059011	(Get FASTA)	NCBI Sequence Viewer
	XP_006254664	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD30367	(Get FASTA)	NCBI Sequence Viewer
	AAH78851	(Get FASTA)	NCBI Sequence Viewer
	EDL76269	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000072205
	ENSRNOP00000072205.2
GenBank Protein	Q9WTW7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_059011 ⟸ NM_017315

- UniProtKB:

Q9WTW7 (UniProtKB/Swiss-Prot), A6J2Y7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKAQEDPGSSKQHECPDSAGTSTRDQQAPLPAEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFS
GTIAVPFLLAEALCVGRDQHMISQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAI
LALERWKCPPEEEIYGNWSMPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLSYIGP
LTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRI
QIFKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGL
PTVTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGVCCIIAGLLGTGN
GSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITA
VGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGVPEVDQILTVLLTTEMFVGG
CLAFILDNTVPGSPEERGLIQWKAGAHANSETLASLKSYDFPFGMGMVKRTTFFRYIPICPVFR
GFSKTENQPAVLEDAPDNTETGSVCTKV

hide sequence

RefSeq Acc Id:	XP_006254664 ⟸ XM_006254602
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2R5A1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKQLPSWKAMLPVGPWLSLCPCAPDGTRAQQLRMKELTHAAPEGRCDSAYTNTEISQTRVSEMK AQEDPGSSKQHECPDSAGTSTRDQQAPLPAEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGT IAVPFLLAEALCVGRDQHMISQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILA LERWKCPPEEEIYGNWSMPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLSYIGPLT VTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQI FKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGLPT VTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGVCCIIAGLLGTGNGS TSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITAVG LSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGVPEVDQILTVLLTTEMFVGGCL AFILDNTVPGSPEERGLIQWKAGAHANSETLASLKSYDFPFGMGMVKRTTFFRYIPICPVFRGF SKTENQPAVLEDAPDNTETGSVCTKV hide sequence

RefSeq Acc Id:

ENSRNOP00000073343 ⟸ ENSRNOT00000078202

RefSeq Acc Id:

ENSRNOP00000072205 ⟸ ENSRNOT00000084372

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9WTW7-F1-model_v2	AlphaFold	Q9WTW7	1-604	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700710

Promoter ID:

EPDNEW_R11232

Type:

initiation region

Name:

Slc23a1_1

Description:

solute carrier family 23 member 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	28,425,981 - 28,426,041	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619875	AgrOrtholog
BioCyc Gene	G2FUF-7901	BioCyc
Ensembl Genes	ENSRNOG00000061695	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000084372.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7127602	IMAGE-MGC_LOAD
InterPro	NCS2	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
KEGG Report	rno:50621	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93503	IMAGE-MGC_LOAD
NCBI Gene	50621	ENTREZGENE
PANTHER	PTHR11119:SF21	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Xan_ur_permease	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Slc23a1	PhenoGen
RatGTEx	ENSRNOG00000061695	RatGTEx
UniProt	A0A8L2R5A1	ENTREZGENE, UniProtKB/TrEMBL
	A6J2Y7	ENTREZGENE, UniProtKB/TrEMBL
	Q9WTW7	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-24	Slc23a1	solute carrier family 23 member 1	Slc23a1	solute carrier family 23 (ascorbic acid transporter), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Slc23a1	solute carrier family 23 (ascorbic acid transporter), member 1	Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-04-22	Slc23a1	solute carrier family 23 (nucleobase transporters), member 1	SVCT1	sodium-coupled ascorbic acid transporter 1	Symbol and Name updated to reflect Human and Mouse nomenclature	625702	APPROVED
2002-08-07	SVCT1	sodium-coupled ascorbic acid transporter 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expression is confined to intestine, kidney, and liver	634186
gene_process	regulates the supply and metabolism of vitamin C	634186

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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