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Gene: Dmbt1 (deleted in malignant brain tumors 1) Rattus norvegicus

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Symbol:

Dmbt1

Name:

deleted in malignant brain tumors 1

RGD ID:

61984

Description:

Predicted to enable several functions, including heparan sulfate binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including response to biphenyl; response to estrogen; and tissue regeneration. Located in extracellular matrix. Biomarker of pheochromocytoma. Human ortholog(s) of this gene implicated in glioblastoma. Orthologous to human DMBT1 (deleted in malignant brain tumors 1); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

crp-ductin; Crpd; Dbmt1; deleted in malignant brain tumors 1 protein; deleted in malignant brain tumors 1 protein-like; ebnerin; hensin; LOC100361701; LOC100911344; LOC691969; pancrin; scavenger receptor cysteine-rich domain-containing protein DMBT1; similar to deleted in malignant brain tumors 1 isoform a precursor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	195,047,702 - 195,126,704 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	195,047,713 - 195,126,704 (+)	Ensembl				GRCr8
mRatBN7.2	1	185,617,469 - 185,696,476 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	185,617,294 - 185,696,478 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	193,967,662 - 194,046,681 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	201,145,205 - 201,224,201 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	193,816,971 - 193,895,963 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	201,620,642 - 201,689,905 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	1	203,149,414 - 203,228,705 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	208,653,663 - 208,723,393 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	1	210,207,368 - 210,243,040 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	190,378,428 - 190,470,536 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	183,224,487 - 183,303,321 (+)	NCBI		Celera
RGSC_v3.1	1	190,528,292 - 190,620,410 (+)	NCBI
Cytogenetic Map	1	q41	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Colonic Neoplasms (ISO)

glioblastoma (ISO)

hereditary breast ovarian cancer syndrome (ISO)

Nose Neoplasms (IEP)

pheochromocytoma (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (EXP)

2-nitrofluorene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (EXP)

3,3',5-triiodo-L-thyronine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (EXP)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (EXP,ISO)

alachlor (EXP)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

anthracen-2-amine (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-naphthoflavone (EXP)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

carnosic acid (ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP,ISO)

chromium(6+) (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

copper atom (EXP)

copper(0) (EXP)

dibutyl phthalate (EXP)

estrone (EXP)

ethanol (EXP)

flavonoids (EXP)

folic acid (ISO)

fulvestrant (EXP,ISO)

fumonisin B1 (ISO)

genistein (ISO)

glafenine (EXP)

indole-3-methanol (EXP)

ivermectin (ISO)

lead diacetate (ISO)

Licochalcone B (ISO)

metformin (EXP)

methapyrilene (ISO)

methylmercury chloride (EXP)

N-methyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP)

okadaic acid (ISO)

ozone (ISO)

paraquat (EXP)

phenformin (EXP)

PhIP (EXP)

pioglitazone (ISO)

pirinixic acid (ISO)

progesterone (ISO)

raloxifene (EXP,ISO)

resveratrol (EXP,ISO)

senecionine (ISO)

silicon dioxide (EXP,ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

streptozocin (EXP)

tamibarotene (ISO)

tamoxifen (EXP,ISO)

temozolomide (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

tributylstannane (ISO)

XL147 (ISO)

zearalenone (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antimicrobial humoral immune response mediated by antimicrobial peptide (ISO)

blastocyst development (ISO)

cell differentiation (IEA,IEP)

defense response to Gram-negative bacterium (IBA,ISO,ISS)

defense response to Gram-positive bacterium (IBA,ISO,ISS)

inner cell mass cell proliferation (ISO)

positive regulation of epithelial cell differentiation (ISO)

protein transport (IEA)

receptor-mediated endocytosis (ISO)

response to bacterium (ISO)

response to biphenyl (IEP)

response to estrogen (IEP)

tissue regeneration (IEP)

Cellular Component

cytoplasm (ISO)

cytoplasmic vesicle (IEA)

extracellular matrix (IBA,IDA,ISO,ISS)

extracellular region (IEA)

extracellular space (IBA,ISO)

membrane (IEA)

phagocytic vesicle membrane (ISO)

transport vesicle membrane (IEA)

zymogen granule membrane (ISO,ISS)

Molecular Function

DNA binding (ISO)

heparan sulfate binding (ISO)

lipopolysaccharide binding (ISO)

lipoteichoic acid binding (ISO)

pattern recognition receptor activity (ISO)

protein binding (ISO)

scavenger receptor activity (IBA,ISO)

zymogen binding (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1.	Bisgaard HC, etal., Am J Pathol 2002 Oct;161(4):1187-98.
2.	Gene expression profiling of rat pheochromocytoma.	Elkahloun AG, etal., Ann N Y Acad Sci. 2006 Aug;1073:290-9.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Genomic analysis of alachlor-induced oncogenesis in rat olfactory mucosa.	Genter MB, etal., Physiol Genomics. 2002 Dec 26;12(1):35-45.
5.	Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3.	Hikita C, etal., J Cell Biol. 2000 Dec 11;151(6):1235-46.
6.	Molecular cloning of Ebnerin, a von Ebner's gland protein associated with taste buds.	Li XJ and Snyder SH, J Biol Chem 1995 Jul 28;270(30):17674-9.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours.	Mollenhauer J, etal., Nat Genet. 1997 Sep;17(1):32-9.
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Comprehensive gene review and curation	RGD comprehensive gene curation
12.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
13.	The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium.	Tynan S, etal., Endocrinology. 2005 Mar;146(3):1066-73. Epub 2004 Nov 24.

Additional References at PubMed

PMID:7876332	PMID:9247472	PMID:10485905	PMID:11007786	PMID:12884308	PMID:15292166	PMID:15452149	PMID:19189310	PMID:19199708	PMID:22664934	PMID:23012479	PMID:36916375

Genomics

Comparative Map Data

Dmbt1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	195,047,702 - 195,126,704 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	195,047,713 - 195,126,704 (+)	Ensembl				GRCr8
mRatBN7.2	1	185,617,469 - 185,696,476 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	185,617,294 - 185,696,478 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	193,967,662 - 194,046,681 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	201,145,205 - 201,224,201 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	193,816,971 - 193,895,963 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	201,620,642 - 201,689,905 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	1	203,149,414 - 203,228,705 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	208,653,663 - 208,723,393 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	1	210,207,368 - 210,243,040 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	190,378,428 - 190,470,536 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	183,224,487 - 183,303,321 (+)	NCBI		Celera
RGSC_v3.1	1	190,528,292 - 190,620,410 (+)	NCBI
Cytogenetic Map	1	q41	NCBI

DMBT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	122,560,754 - 122,643,736 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	122,560,643 - 122,643,740 (+)	Ensembl			hg38	GRCh38
GRCh37	10	124,320,270 - 124,403,252 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	124,310,171 - 124,393,242 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	124,310,170 - 124,393,242	NCBI
Celera	10	118,052,442 - 118,110,650 (+)	NCBI		Celera
Cytogenetic Map	10	q26.13	NCBI
HuRef	10	117,951,140 - 118,021,117 (+)	NCBI		HuRef
CHM1_1	10	124,604,802 - 124,685,026 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	123,456,615 - 123,518,779 (+)	NCBI		T2T-CHM13v2.0

Dmbt1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	130,633,787 - 130,723,357 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	130,633,776 - 130,723,357 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	131,032,057 - 131,121,628 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	131,032,046 - 131,121,628 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	138,175,590 - 138,265,142 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	130,823,224 - 130,912,776 (+)	NCBI		MGSCv36	mm8
Celera	7	130,843,517 - 130,932,972 (+)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	73.2	NCBI

Dmbt1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955477	863,388 - 899,703 (+)	NCBI	ChiLan1.0	ChiLan1.0

DMBT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	134,416,181 - 134,487,065 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	134,421,533 - 134,492,318 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	119,129,440 - 119,200,232 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	122,540,855 - 123,474,497 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	122,540,855 - 123,474,497 (+)	Ensembl			panPan2	panpan1.1

DMBT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	32,198,250 - 32,286,517 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	32,219,448 - 32,286,532 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	32,273,452 - 32,352,858 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	32,734,599 - 32,843,241 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	28	32,266,372 - 32,367,335 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	32,288,134 - 32,391,575 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	32,492,566 - 32,643,099 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

LOC101959402
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	14,015,522 - 14,082,223 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936486	11,377,485 - 11,545,624 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DMBT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	14	132,154,346 - 132,231,274 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	43,728,925 - 43,753,137 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DMBT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	115,344,861 - 115,346,308 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	76,594,741 - 76,679,974 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dmbt1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624737	24,135,083 - 24,164,935 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Dmbt1
593 total Variants

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	153679879	198679879	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	177339686	222339686	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	181059071	226059071	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	181059071	226059071	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	153679879	205813246	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	182039247	227039247	Rat
8694166	Bw147	Body weight QTL 147	6.83	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	1	153788989	198788989	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	183564652	228564652	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631838	Niddm36	Non-insulin dependent diabetes mellitus QTL 36		0.01	insulin secretion trait (VT:0003564)	calculated pancreatic islet insulin release measurement (CMO:0001217)	1	193964073	238964073	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	160573753	210707719	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	181059071	226059071	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	160573753	210707719	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	165278545	210278545	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	161077990	206077990	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	181059071	226059071	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	181059071	226059071	Rat
1300145	Rf7	Renal function QTL 7	2.96		urine creatinine amount (VT:0010540)	urine creatinine level (CMO:0000125)	1	194575422	239575422	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	168063662	213063662	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	193400541	238400541	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	159894717	207261263	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	163992710	208992710	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	182535316	227535316	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	181059071	226059071	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	181059071	226059071	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	181059071	226059071	Rat
1359018	Hrtrt20	Heart rate QTL 20	3.08		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	194786607	207590403	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	162753891	207753891	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	180739993	225739993	Rat
61378	Bp43	Blood pressure QTL 43	22.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	191177449	205813246	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	191190115	223964326	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	172718770	228180370	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	186298393	231298393	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	175967553	200707874	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
619614	Bp78	Blood pressure QTL 78		0.001	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	178547286	206690557	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	194786607	262083703	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	188241285	250779312	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
1300168	Bp170	Blood pressure QTL 170	2.76		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	192995199	237995199	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	186298393	231298393	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	186298393	231298393	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	185979875	230979875	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	210707719	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	193400541	238400541	Rat
1576310	Schws2	Schwannoma susceptibility QTL 2		0.029	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	1	153788989	198788989	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	165707719	210707719	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	173363824	227535316	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	191260175	236260175	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2325727	Pia41	Pristane induced arthritis QTL 41			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	188241285	233241285	Rat
7411599	Foco11	Food consumption QTL 11	18.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	1	153788989	198788989	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	210707719	Rat
2325725	Eae31	Experimental allergic encephalomyelitis QTL 31			nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	188241285	197807511	Rat
631670	Iddm10	Insulin dependent diabetes mellitus QTL 10	1.9		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	183564652	205813246	Rat

Markers in Region

D1Rat110

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	185,635,395 - 185,635,534 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	201,638,095 - 201,638,231	NCBI	Rnor6.0
Rnor_5.0	1	208,671,125 - 208,671,261	UniSTS	Rnor5.0
RGSC_v3.4	1	190,396,289 - 190,396,654	RGD	RGSC3.4
RGSC_v3.4	1	190,396,336 - 190,396,472	UniSTS	RGSC3.4
Celera	1	183,242,431 - 183,242,567	UniSTS
RGSC_v3.1	1	190,546,170 - 190,546,535	RGD
RH 3.4 Map	1	1426.9	UniSTS
RH 3.4 Map	1	1426.9	RGD
FHH x ACI Map	1	88.84	UniSTS
FHH x ACI Map	1	88.84	RGD
Cytogenetic Map	1	q37	UniSTS

D1Rat470

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RGSC_v3.4	1	190,403,127 - 190,403,344	UniSTS	RGSC3.4
RGSC_v3.4	1	190,403,126 - 190,403,344	RGD	RGSC3.4
Celera	1	183,249,222 - 183,249,421	UniSTS
RGSC_v3.1	1	190,553,007 - 190,553,225	RGD
FHH x ACI Map	1	89.99	UniSTS
FHH x ACI Map	1	89.99	RGD
Cytogenetic Map	1	q37	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
7	1	10	1	20	10	8	4	3	32	2	2

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001429894	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_022849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590468	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY548057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U32681	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000054910 ⟹ ENSRNOP00000051793

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	195,047,713 - 195,126,704 (+)	Ensembl
mRatBN7.2 Ensembl	1	185,617,294 - 185,696,478 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093289 ⟹ ENSRNOP00000076172

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	195,047,713 - 195,126,704 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093308 ⟹ ENSRNOP00000076279

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	185,617,294 - 185,696,478 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093490 ⟹ ENSRNOP00000076163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	195,047,713 - 195,126,704 (+)	Ensembl
mRatBN7.2 Ensembl	1	185,617,294 - 185,696,478 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093674 ⟹ ENSRNOP00000076237

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	195,047,713 - 195,126,704 (+)	Ensembl
mRatBN7.2 Ensembl	1	185,617,294 - 185,696,478 (+)	Ensembl

RefSeq Acc Id:

NM_022849 ⟹ NP_074040

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	195,047,702 - 195,126,704 (+)	NCBI
mRatBN7.2	1	185,617,469 - 185,696,476 (+)	NCBI
Rnor_6.0	1	201,620,642 - 201,689,905 (+)	NCBI
Rnor_5.0	1	210,207,368 - 210,243,040 (+)	NCBI
Celera	1	183,224,487 - 183,303,321 (+)	NCBI

Sequence:

show sequence

GAGAGGAACCAGCACAATGGGGATCTCCATCGTTATCTTTGAAATATGTCTTTTGTGGGGTCAA
ATTCTTTCTACAGCTTCTCAATCAAGAAGTTCCACACCTGATTGGTGGAACCATGGGGGCACAA
TTAATGATGTGATCTACGACACTCAAGAAACCCCAGAAGTGACGACTACTCAAGTTCCTGATTC
CACATCAATAGGAACAGATTCTGGTTTGGCTGTGAGGCTGGTGAATGGAGGAGACAGGTGTCGG
GGTCGCGTGGAGATCCTTTACCAGGGTTCCTGGGGCACCATGTGTGATGACGGAACAGATTCTG
GTTTGGCTGTGAGGCTGGTGAATGGAGGAGACAGGTGTCGGGGTCGCGTGGAGATCCTTTACCA
GGGTTCCTGGGGCACCATGTGTGATGACAGCTGGGACATCAATGATGCCAACGTGGTGTGCAGG
CAGCTGGGCTGTGGCTGGGCCTTGTCTGCCCCAGGAAGTGCCCAGTTTGGACAGGGTCTGGGTC
CCATTGTTCTGGATGACGTGGCCTGTAGAGGACATGAGGCCTATCTGTGGAGCTGCTCCCACCG
AGGCTGGCTCTCTCATAACTGTGGACATCAGGAGGATGCTGGAGTGATCTGCTCAGATTCTCAA
ACAAGCAGTCCCACACCCGGTTGGTGGAACCCCGGGGGCACAAATAACGATGTGATCTACGACA
CTCAAGAAACCACAGAAACTTCTCAAACAAGCAGTCCCACACCTGATTGGTGGAACCATGGGGG
CACAATTAATGATGTGATCTATGACACTCAAGAAACCACAGAAGGAACAGATTCTGGTTTGGCT
GTGAGGCTGGTGAATGGAGGAGACAGGTGTCGGGGTCGTGTGGAGATCCTTTACCAGGGTTCCT
GGGGCACCGTGTGTGACGACAGCTGGGACATCAATGATGCCAACGTGGTGTGCAGGCAGCTGGG
CTGTGGCTGGGCCTTGTCTGCCCCAGGAAGTGCCCAGTTTGGACAGGGCTCTGGGTCCATTGTT
CTGGATGACGTGGCCTGTAGAGGACATGAGGCCTATCTGTGGAGCTGCTCCCACCGAGGCTGGC
TCTCTCATAACTGTGGACATCAGGAGGATGCTGGAGTCATCTGTTCATATTCTCAAACAAGCAG
TCCCACACCCGATTCTCAAACAAGCAGTCCCACACCCGGTTGGTGGAACCCCGGGGGCACAAAT
AACGATGTGTCCTATGGACCCGAACAGACCACAGACGCAACAGATTCTGGTTTGGCTGTGAGGC
TGGTGAATGGAGGAGACAGGTGTCAGGGTCGTGTGGAGATCCTTTACCAGGGTTCCTGGGGTAC
CGTGTGTGACGACAGCTGGGACACCAAGGATGCCAACGTGGTGTGCAGGCAGCTGGTCTGTGGC
TGGGCCTTGTCTGCCCCAGGAAGTGCCCACTTTGGACAAGGCTCTGGATCCATTGTTCTGGATG
ACGTGGCCTGTACAGGACATGAGGCCTATCTGTGGAGCTGCTCCCACCGAGGCTGGCTCTCTCA
TAACTGTGGCCACCATGAGGATGCTGGAGTCATCTGTTCAGATGCCCAAACCCAGAGCACAACC
TGGCCAGATATGTGGCCTACTACCACTCCAGAAACTACAACAGATTGGTGGACTACAAAATATT
CTTCCTCTGTTCCTACAACACAATTCCCCACCATAGCCGATTGGTGGACAACTCCTTCTCCGGA
ATACACCTGTGGAGGTTTACTGACCCTACCCTATGGGCAGTTTTCCAGCCCATACTACCCTGGA
AGCTATCCTAACAATGCCAGATGTTTGTGGAAAATTTTCGTCTCCAGCATGAACCGTGTGACAG
TGGTCTTCACAGATGTGCAGCTTGAAGGAGGTTGCAACTATGACTACATCCTGGTTTTTGATGG
CCCTGAAAACAATTCTTCTCTCATTGCTCGGGTTTGTGATGGGTTCAATGGATCTTTCACCTCA
ACCCAGAACTTCATGTCTGTAGTCTTTATCACGGATGGCAGTGTCACGAGGAGAGGGTTCCAAG
CTGACTACTACTCCACTCCTATCAGCACCAGCACAACCTCTCCAACGACGTTCCCGATCGTTAC
TGATTGGTGGACAACTCCTTCTCCGGAATACACCTGTGGAGGTTTACTGACCCTACCCTATGGG
CAGTTTTCCAGCCCATACTACCCTGGAAGCTATCCTAACAATGCCAGATGTTTGTGGAAAATTT
TCGTCCCCAGCATGAACCGTGTGACAGTGGTCTTCACAGATGTGCAGCTTGAAGGAGGTTGCAA
CTATGACTACATCCTGGGTTTTGATGGTCCTGAATACAATTCTTCTCTCATTGCTCGGGTTTGT
GATGGGTCCAATGGATCTTTCACCTCAACCCAGAACTTCATGTCTGTAGTCTTTATCACGGATG
GCAGTGTCACGAGGAGAGGGTTCCAAGCTGACTACTACTCCACTCCTATCAGGACCAGCACAAC
TCCTCCAACGACGTTCCCGATCATTACTGGAAATGATTCTTCATTGGTGCTGAGGCTGGTAAAT
GGAACAAACCGGTGTGAGGGCCGAGTGGAGATCTTGTACAGAGGCTCTTGGGTACCGTGTGCCG
ACGACAGCTGGGACATCAATGATGCCAATGTGGTCTGCAGACAGCTCGGTTGTGGCTCTGCTCT
GTCTGCTCCAGGAAATGCTTGGTTTGGTCAGGGTTCAGGGCTCATTGTCCTGGATGATGTGTCT
TGCTCTGGGTATGAGTCCCACCTGTGGAATTGTCGTCACCCTGGCTGGCTTGTTCATAATTGTC
GTCATGTTGAGGATGCAGGAGTCATTTGCTCACTCCCTGATCCGACTCCCTCTCCTGGTCCAGT
TTGGACAAGTCCTCCTTTTGTAAACTATACTTGTGGAGGTTTCCTGACTGGACTCTCTGGGCAA
TTTTCTAGCCCATACTACCCTGGGAGCTATCCTAATAATGCCAGATGTTTGTGGAACATTGAAG
TCCCAAACAACTACCGCGTGACTGTGGTCTTCAGAGATGTGCAGCTGGAAGGGGGCTGCAACTA
TGACTATATAGAGATTTTTGATGGCCCCCACCACAGTTCACCTCTCATTGCCCGGGTTTGTGAT
GGGGCCATGGGCTCTTTCACTTCAACATCCAACTTCATGTCAGTTCGCTTCACCACTGATCACA
GTGTTACTCGAAGAGGGTTCCGGGCTGACTACTACTCAGACTTTGACAATAATACCACCAATCT
CCTTTGTCTGTCAAATCACATGAGAGCCAGTGTGAGCAGGAGCTACCTTCAGTCCATGGGCTAC
TCCTCCAGGGATCTTGTCATTCCTGGTTGGAACGTGAGTTACCAGTGTCAGCCTCAGATAACAC
AAAGGGAGGTCATATTCACAATTCCCTACACAGGCTGCGGTACTACCAAACAGGCTGACAACGA
GACCATCAACTACTCCAACTTCCTCAAAGCGGCTGTTTCAAATGGCATCATCAAAAGGAGAAAG
GATCTCCACATCCATGTCAGCTGCAAGATGCTTCAGAACACCTGGGTCAACACCATGTACATCA
CCAACAACACAGTCGAGATCCAGGAAGTCCAGTATGGCAATTTTGACGTGAATATTTCCTTTTA
TACATCCTCCTCCTTCTTGTATCCAGTGACCAGCAGCCCATATTATGTGGATCTGGACCAGAAT
TTGTACCTTCAGGCCGAAGTCCTCCATTCGGATACCTCTTTGGCTCTGTTTGTGGACACCTGTG
TGGCTTCGCCACATCCCAATGACTTCTCGTCTTTGACATATGATCTCATCAGGAGTGGATGCAT
ACGAGATGAAACTTACCAATCTTACTCCTCGCCCTCACCACGCATCACCCGCTTTAAATTCAGT
TCTTTCCACTTCCTGAACCGCTTCCCCTCAGTATACCTACAGTGTAAACTGGTGGTTTGTCGAG
CAAACGATGTCTCCTCACGGTGCTACAGAGGATGTGTAGTAAGGTCCAAGAGGGATGTAGGCTC
CTACCAAGAAAAGGTGGATGTTGTTCTGGGACCCATCCAGTTGCAATCTCCCAGCAAAGAAAAG
AGGAGTCTCGACTTGGCAGTGGCAGATGTGGAGAAGCCAGCCAGCTCCCAGGAGGTCTATCCCA
CTGCAGCCATCTTTGGTGGAGTCTTCCTGGCCCTGGTTGTAGCTGTGGCAGCCTTCACACTGGG
AAGGAAGACACGCACTGCCCGTGGTCAACCTCCAAGTACTAAGATGTGAAGCAAAACAACCCAG
ACATTGGTCCCAAATGCATAGATTCCCAGAAAAGATGGAAGTCAGGAGTGTCTAATGCCTGGCA
CCCAGATACACGATGACTAGGCTTCCCTTAGCACAAATGTGTGGCCGAGTATGATCAGATGGTA
AAGAAGAAAGGTGGGGGCCAAGTTTTCCCAGGGTCTAGAGGCTGAAGGCTGGGAAGAATGTCAT
AGGAGAATGAGATCAGTGTCTACAATAACAGGCAACTGTGAGCCAAACATTGGCATCACCATCC
TTTCTCTAGCTAGAATTTCCCTTTCCCCCTTTTATACTGACTTTTTTGAACTGTAGTGTTAAAT
GGACCTTTCCGTACAACAAACTAAAATAAAGAATCTTTTTCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001416823	(Get FASTA)	NCBI Sequence Viewer
	NP_074040	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC52248	(Get FASTA)	NCBI Sequence Viewer
	AAS46613	(Get FASTA)	NCBI Sequence Viewer
	Q8CIZ5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_074040 ⟸ NM_022849

- Peptide Label:

precursor

- Sequence:

show sequence

MGISIVIFEICLLWGQILSTASQSRSSTPDWWNHGGTINDVIYDTQETPEVTTTQVPDSTSIGT
DSGLAVRLVNGGDRCRGRVEILYQGSWGTMCDDGTDSGLAVRLVNGGDRCRGRVEILYQGSWGT
MCDDSWDINDANVVCRQLGCGWALSAPGSAQFGQGLGPIVLDDVACRGHEAYLWSCSHRGWLSH
NCGHQEDAGVICSDSQTSSPTPGWWNPGGTNNDVIYDTQETTETSQTSSPTPDWWNHGGTINDV
IYDTQETTEGTDSGLAVRLVNGGDRCRGRVEILYQGSWGTVCDDSWDINDANVVCRQLGCGWAL
SAPGSAQFGQGSGSIVLDDVACRGHEAYLWSCSHRGWLSHNCGHQEDAGVICSYSQTSSPTPDS
QTSSPTPGWWNPGGTNNDVSYGPEQTTDATDSGLAVRLVNGGDRCQGRVEILYQGSWGTVCDDS
WDTKDANVVCRQLVCGWALSAPGSAHFGQGSGSIVLDDVACTGHEAYLWSCSHRGWLSHNCGHH
EDAGVICSDAQTQSTTWPDMWPTTTPETTTDWWTTKYSSSVPTTQFPTIADWWTTPSPEYTCGG
LLTLPYGQFSSPYYPGSYPNNARCLWKIFVSSMNRVTVVFTDVQLEGGCNYDYILVFDGPENNS
SLIARVCDGFNGSFTSTQNFMSVVFITDGSVTRRGFQADYYSTPISTSTTSPTTFPIVTDWWTT
PSPEYTCGGLLTLPYGQFSSPYYPGSYPNNARCLWKIFVPSMNRVTVVFTDVQLEGGCNYDYIL
GFDGPEYNSSLIARVCDGSNGSFTSTQNFMSVVFITDGSVTRRGFQADYYSTPIRTSTTPPTTF
PIITGNDSSLVLRLVNGTNRCEGRVEILYRGSWVPCADDSWDINDANVVCRQLGCGSALSAPGN
AWFGQGSGLIVLDDVSCSGYESHLWNCRHPGWLVHNCRHVEDAGVICSLPDPTPSPGPVWTSPP
FVNYTCGGFLTGLSGQFSSPYYPGSYPNNARCLWNIEVPNNYRVTVVFRDVQLEGGCNYDYIEI
FDGPHHSSPLIARVCDGAMGSFTSTSNFMSVRFTTDHSVTRRGFRADYYSDFDNNTTNLLCLSN
HMRASVSRSYLQSMGYSSRDLVIPGWNVSYQCQPQITQREVIFTIPYTGCGTTKQADNETINYS
NFLKAAVSNGIIKRRKDLHIHVSCKMLQNTWVNTMYITNNTVEIQEVQYGNFDVNISFYTSSSF
LYPVTSSPYYVDLDQNLYLQAEVLHSDTSLALFVDTCVASPHPNDFSSLTYDLIRSGCIRDETY
QSYSSPSPRITRFKFSSFHFLNRFPSVYLQCKLVVCRANDVSSRCYRGCVVRSKRDVGSYQEKV
DVVLGPIQLQSPSKEKRSLDLAVADVEKPASSQEVYPTAAIFGGVFLALVVAVAAFTLGRKTRT
ARGQPPSTKM

hide sequence

Ensembl Acc Id:

ENSRNOP00000076237 ⟸ ENSRNOT00000093674

Ensembl Acc Id:

ENSRNOP00000051793 ⟸ ENSRNOT00000054910

Ensembl Acc Id:

ENSRNOP00000076279 ⟸ ENSRNOT00000093308

Ensembl Acc Id:

ENSRNOP00000076163 ⟸ ENSRNOT00000093490

Ensembl Acc Id:

ENSRNOP00000076172 ⟸ ENSRNOT00000093289

Protein Domains

CUB SRCR ZP

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZZV0-F1-model_v2	AlphaFold	D3ZZV0	1-1034	view protein structure
AF-Q8CIZ5-F1-model_v2	AlphaFold	Q8CIZ5	1-1418	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61984	AgrOrtholog
BioCyc Gene	G2FUF-57244	BioCyc
Ensembl Genes	ENSRNOG00000020560	Ensembl
	ENSRNOG00000090509	Ensembl, ENTREZGENE
Gene3D-CATH	2.60.120.290	UniProtKB/Swiss-Prot
	2.60.40.4100	UniProtKB/Swiss-Prot
	3.10.250.10	UniProtKB/Swiss-Prot
	Zona pellucida, ZP-N domain	UniProtKB/Swiss-Prot
InterPro	CUB_dom	UniProtKB/Swiss-Prot
	SJ_maturation_regulator	UniProtKB/Swiss-Prot
	Sperma_CUB_dom_sf	UniProtKB/Swiss-Prot
	SRCR	UniProtKB/Swiss-Prot
	SRCR-like_dom_sf	UniProtKB/Swiss-Prot
	ZP-C	UniProtKB/Swiss-Prot
	ZP-C	UniProtKB/Swiss-Prot
	ZP-N	UniProtKB/Swiss-Prot
	ZP_dom	UniProtKB/Swiss-Prot
	ZP_dom_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:170568	UniProtKB/Swiss-Prot
NCBI Gene	Dmbt1	ENTREZGENE
PANTHER	DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN	UniProtKB/Swiss-Prot
	PROTEIN BARK BEETLE	UniProtKB/Swiss-Prot
Pfam	CUB	UniProtKB/Swiss-Prot
	SRCR	UniProtKB/Swiss-Prot
	Zona_pellucida	UniProtKB/Swiss-Prot
	ZP-N	UniProtKB/Swiss-Prot
PhenoGen	Dmbt1	PhenoGen
PRINTS	SPERACTRCPTR	UniProtKB/Swiss-Prot
PROSITE	CUB	UniProtKB/Swiss-Prot
	SRCR_1	UniProtKB/Swiss-Prot
	SRCR_2	UniProtKB/Swiss-Prot
	ZP_1	UniProtKB/Swiss-Prot
	ZP_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000020560	RatGTEx
	ENSRNOG00000090509	RatGTEx
SMART	CUB	UniProtKB/Swiss-Prot
	SM00202	UniProtKB/Swiss-Prot
	SM00241	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF49854	UniProtKB/Swiss-Prot
	SSF56487	UniProtKB/Swiss-Prot
TIGR	TC207016
UniProt	A0A1W2Q668_RAT	UniProtKB/TrEMBL
	A0A1W2Q688_RAT	UniProtKB/TrEMBL
	A0A1W2Q6D7_RAT	UniProtKB/TrEMBL
	A0A1W2Q6H6_RAT	UniProtKB/TrEMBL
	D3ZZV0	ENTREZGENE, UniProtKB/TrEMBL
	DMBT1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q62827	UniProtKB/Swiss-Prot
	Q6QD54	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Dmbt1	deleted in malignant brain tumors 1	LOC100911344	deleted in malignant brain tumors 1 protein-like	Data merged from RGD:6493486	737654	PROVISIONAL
2013-04-17	Dmbt1	deleted in malignant brain tumors 1	LOC691969	similar to deleted in malignant brain tumors 1 isoform a precursor	Data merged from RGD:1593323	737654	PROVISIONAL
2013-04-17	Dmbt1	deleted in malignant brain tumors 1	LOC100361701	deleted in malignant brain tumors 1	Data merged from RGD:2319573	737654	PROVISIONAL
2012-07-05	LOC100911344	deleted in malignant brain tumors 1 protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2010-05-05	LOC100361701	deleted in malignant brain tumors 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC691969	similar to deleted in malignant brain tumors 1 isoform a precursor			Symbol and Name status set to provisional	70820	PROVISIONAL
2002-06-10	Dmbt1	deleted in malignant brain tumors 1			Name updated	70584	APPROVED
2001-12-06	Dmbt1	deleted in malignant brain tumors 1			Symbol and Name updated to reflect Human and Mouse nomenclature	69665	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	extracellular region contains a number of repeated domains with homology to the scavenger receptor cysteine-rich domain and to a repeated domain of bone morphogenetic protein-I	61559
gene_expression	expressed in secretory duct epithelial cells of von Ebner's glands (VEG)	61559
gene_protein	1290 amino acids	61559

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD