Symbol:
Atrx
Name:
ATRX, chromatin remodeler
RGD ID:
619795
Description:
Predicted to enable several functions, including DNA translocase activity; chromo shadow domain binding activity; and methylated histone binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; chromatin remodeling; and positive regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within several processes, including male gonad development; meiotic spindle organization; and post-embryonic forelimb morphogenesis. Predicted to be located in several cellular components, including chromosomal region; ciliary basal body; and nuclear lumen. Human ortholog(s) of this gene implicated in X-linked mental retardation-hypotonic facies syndrome-1; alpha thalassemia-X-linked intellectual disability syndrome; alpha-thalassemia myelodysplasia syndrome; high grade glioma; and lung small cell carcinoma. Orthologous to human ATRX (ATRX chromatin remodeler); INTERACTS WITH (+)-pilocarpine; 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
alpha thalassemia/mental retardation syndrome X-linked; alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae); alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae); alpha thalassemia/mental retardation syndrome X-linked homolog; alpha thalassemia/mental retardation syndrome X-linked homolog (human); ATP-dependent helicase ATRX; helicase II; LOC103690008; pABP-2; transcriptional regulator ATRX; transcriptional regulator ATRX-like; X-linked nuclear protein; Xnp
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 74,916,548 - 75,062,880 (-) NCBI GRCr8 mRatBN7.2 X 70,850,981 - 70,997,330 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 70,850,981 - 70,997,330 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 72,359,919 - 72,506,253 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 75,860,229 - 76,006,565 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 73,423,392 - 73,569,729 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 76,820,110 - 76,979,155 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 76,820,329 - 76,979,115 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 76,692,970 - 76,708,878 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 77,469,497 - 77,515,204 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Rnor_5.0 X 55,943,493 - 56,101,756 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 93,903,794 - 94,051,337 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 X 94,034,366 - 94,057,029 (-) NCBI Celera X 72,164,814 - 72,309,854 (-) NCBI Celera Cytogenetic Map X q22 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Atrx Rat (+)-dexrazoxane multiple interactions ISO Atrx (Mus musculus) 6480464 [Dexrazoxane co-treated with Idarubicin] results in increased expression of ATRX protein and Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of ATRX mRNA] CTD PMID:28973540 Atrx Rat (+)-pilocarpine increases expression EXP 6480464 Pilocarpine results in increased expression of ATRX mRNA CTD PMID:17971868 Atrx Rat (S)-nicotine increases expression ISO ATRX (Homo sapiens) 6480464 Nicotine results in increased expression of ATRX mRNA CTD PMID:16949557 Atrx Rat (S)-nicotine decreases expression ISO Atrx (Mus musculus) 6480464 Nicotine results in decreased expression of ATRX mRNA CTD PMID:21955143 Atrx Rat 1,2-dichloroethane decreases expression ISO Atrx (Mus musculus) 6480464 ethylene dichloride results in decreased expression of ATRX mRNA CTD PMID:28960355 Atrx Rat 1,2-dimethylhydrazine increases expression ISO Atrx (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of ATRX mRNA CTD PMID:22206623 Atrx Rat 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expression EXP 6480464 chlorcyclizine results in decreased expression of ATRX mRNA CTD PMID:21058326 Atrx Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of ATRX mRNA CTD PMID:20068009 Atrx Rat 17beta-estradiol increases expression ISO ATRX (Homo sapiens) 6480464 Estradiol results in increased expression of ATRX mRNA CTD PMID:36581016 Atrx Rat 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO Atrx (Mus musculus) 6480464 2 more ... CTD PMID:31388691 Atrx Rat 2,3,4,7,8-Pentachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:21724226 Atrx Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Atrx (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of ATRX mRNA CTD PMID:21570461 Atrx Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ATRX mRNA CTD PMID:34747641 Atrx Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ATRX mRNA CTD PMID:32109520 Atrx Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Atrx (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of ATRX mRNA CTD PMID:15034205 Atrx Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Atrx Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of ATRX mRNA CTD PMID:21346803 Atrx Rat 2-butoxyethanol decreases expression ISO Atrx (Mus musculus) 6480464 n-butoxyethanol results in decreased expression of ATRX mRNA CTD PMID:19812364 Atrx Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Atrx (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ATRX mRNA CTD PMID:26251327 Atrx Rat 4-vinylcyclohexene dioxide affects expression ISO Atrx (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of ATRX mRNA CTD PMID:20829426 Atrx Rat acrolein multiple interactions ISO ATRX (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATRX mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATRX mRNA CTD PMID:32699268 Atrx Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of ATRX mRNA CTD PMID:28959563 Atrx Rat aflatoxin B1 increases expression ISO Atrx (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of ATRX mRNA CTD PMID:19770486 Atrx Rat aflatoxin B1 decreases methylation ISO ATRX (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of ATRX intron CTD PMID:30157460 Atrx Rat Aflatoxin B2 alpha increases methylation ISO ATRX (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of ATRX intron CTD PMID:30157460 Atrx Rat all-trans-retinoic acid decreases expression ISO ATRX (Homo sapiens) 6480464 Tretinoin results in decreased expression of ATRX mRNA CTD PMID:15498508 Atrx Rat all-trans-retinoic acid increases expression ISO ATRX (Homo sapiens) 6480464 Tretinoin results in increased expression of ATRX mRNA CTD PMID:23724009 Atrx Rat alpha-pinene multiple interactions ISO ATRX (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATRX mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ATRX mRNA CTD PMID:32699268 Atrx Rat ammonium chloride increases expression EXP 6480464 Ammonium Chloride results in increased expression of ATRX mRNA CTD PMID:12420312 Atrx Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ATRX mRNA CTD PMID:16483693 Atrx Rat antimycin A increases expression ISO ATRX (Homo sapiens) 6480464 Antimycin A results in increased expression of ATRX mRNA CTD PMID:33512557 Atrx Rat antirheumatic drug increases expression ISO ATRX (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of ATRX mRNA CTD PMID:24449571 Atrx Rat aristolochic acid A decreases expression ISO ATRX (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ATRX mRNA CTD PMID:33212167 Atrx Rat benzene decreases expression ISO Atrx (Mus musculus) 6480464 Benzene results in decreased expression of ATRX mRNA CTD PMID:20018183 Atrx Rat benzo[a]pyrene decreases expression ISO Atrx (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of ATRX mRNA CTD PMID:15034205 and PMID:19770486 Atrx Rat benzo[a]pyrene affects methylation ISO ATRX (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ATRX intron and Benzo(a)pyrene affects the methylation of ATRX promoter CTD PMID:27901495 and PMID:30157460 Atrx Rat benzo[a]pyrene increases methylation ISO ATRX (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ATRX exon CTD PMID:27901495 Atrx Rat benzo[a]pyrene diol epoxide I decreases expression ISO ATRX (Homo sapiens) 6480464 7 more ... CTD PMID:20018196 Atrx Rat bis(2-ethylhexyl) phthalate decreases expression ISO Atrx (Mus musculus) 6480464 Diethylhexyl Phthalate results in decreased expression of ATRX mRNA CTD PMID:33754040 Atrx Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ATRX mRNA CTD PMID:25181051 Atrx Rat bisphenol A affects methylation ISO ATRX (Homo sapiens) 6480464 bisphenol A affects the methylation of ATRX gene CTD PMID:31601247 Atrx Rat bisphenol A multiple interactions ISO ATRX (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of ATRX gene CTD PMID:31601247 Atrx Rat bisphenol A decreases expression ISO Atrx (Mus musculus) 6480464 bisphenol A results in decreased expression of ATRX mRNA CTD PMID:33221593 Atrx Rat bisphenol A increases expression ISO ATRX (Homo sapiens) 6480464 bisphenol A results in increased expression of ATRX mRNA CTD PMID:29275510 Atrx Rat Brevetoxin B decreases expression ISO ATRX (Homo sapiens) 6480464 brevetoxin 2 results in decreased expression of ATRX mRNA CTD PMID:20498034 Atrx Rat Brodifacoum increases expression EXP 6480464 bromfenacoum results in increased expression of ATRX protein CTD PMID:28903499 Atrx Rat butanal decreases expression ISO ATRX (Homo sapiens) 6480464 butyraldehyde results in decreased expression of ATRX mRNA CTD PMID:26079696 Atrx Rat caffeine affects phosphorylation ISO ATRX (Homo sapiens) 6480464 Caffeine affects the phosphorylation of ATRX protein CTD PMID:35688186 Atrx Rat carbon nanotube decreases expression ISO Atrx (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Atrx Rat chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of ATRX mRNA CTD PMID:23125180 Atrx Rat clobetasol decreases expression ISO Atrx (Mus musculus) 6480464 Clobetasol results in decreased expression of ATRX mRNA CTD PMID:27462272 Atrx Rat clorgyline increases expression ISO ATRX (Homo sapiens) 6480464 Clorgyline results in increased expression of ATRX mRNA CTD PMID:19691856 Atrx Rat cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of ATRX mRNA CTD PMID:24386269 Atrx Rat cocaine increases expression EXP 6480464 Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 Atrx Rat coumarin affects phosphorylation ISO ATRX (Homo sapiens) 6480464 coumarin affects the phosphorylation of ATRX protein CTD PMID:35688186 Atrx Rat CU-O LINKAGE decreases expression ISO ATRX (Homo sapiens) 6480464 cupric oxide results in decreased expression of ATRX mRNA CTD PMID:22077320 Atrx Rat cyclosporin A decreases expression ISO Atrx (Mus musculus) 6480464 Cyclosporine results in decreased expression of ATRX mRNA CTD PMID:19770486 Atrx Rat cyclosporin A decreases expression ISO ATRX (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ATRX mRNA CTD PMID:25562108 and PMID:27989131 Atrx Rat cypermethrin increases expression ISO Atrx (Mus musculus) 6480464 cypermethrin results in increased expression of ATRX mRNA CTD PMID:21142847 Atrx Rat deoxynivalenol affects phosphorylation ISO Atrx (Mus musculus) 6480464 deoxynivalenol affects the phosphorylation of ATRX protein CTD PMID:23811945 Atrx Rat diazinon increases expression EXP 6480464 Diazinon results in increased expression of ATRX mRNA CTD PMID:29108742 Atrx Rat diazinon increases methylation ISO ATRX (Homo sapiens) 6480464 Diazinon results in increased methylation of ATRX gene CTD PMID:22964155 Atrx Rat Dibutyl phosphate affects expression ISO ATRX (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of ATRX mRNA CTD PMID:37042841 Atrx Rat diquat increases expression ISO Atrx (Mus musculus) 6480464 Diquat results in increased expression of ATRX protein CTD PMID:36851058 Atrx Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of ATRX mRNA CTD PMID:25152437 Atrx Rat dorsomorphin multiple interactions ISO ATRX (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATRX mRNA CTD PMID:27188386 Atrx Rat doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of ATRX mRNA CTD PMID:27181935 Atrx Rat doxorubicin increases expression ISO ATRX (Homo sapiens) 6480464 Doxorubicin results in increased expression of ATRX mRNA CTD PMID:36634904 Atrx Rat doxorubicin multiple interactions ISO ATRX (Homo sapiens) 6480464 [TP53 protein affects the susceptibility to Doxorubicin] which affects the expression of ATRX mRNA more ... CTD PMID:36634904 and PMID:38367682 Atrx Rat doxorubicin decreases expression ISO ATRX (Homo sapiens) 6480464 Doxorubicin results in decreased expression of ATRX mRNA CTD PMID:29803840 Atrx Rat doxorubicin multiple interactions EXP 6480464 Fungal Polysaccharides inhibits the reaction [Doxorubicin results in increased expression of ATRX mRNA] CTD PMID:27181935 Atrx Rat elemental selenium multiple interactions ISO ATRX (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA CTD PMID:19244175 Atrx Rat elemental selenium decreases expression ISO ATRX (Homo sapiens) 6480464 Selenium results in decreased expression of ATRX mRNA CTD PMID:19244175 Atrx Rat Enterolactone decreases expression ISO ATRX (Homo sapiens) 6480464 2 and 3-bis(3'-hydroxybenzyl)butyrolactone results in decreased expression of ATRX mRNA CTD PMID:19167446 Atrx Rat ethanol decreases expression ISO Atrx (Mus musculus) 6480464 Ethanol results in decreased expression of ATRX mRNA CTD PMID:21955143 Atrx Rat ethanol affects splicing ISO Atrx (Mus musculus) 6480464 Ethanol affects the splicing of ATRX mRNA CTD PMID:30319688 Atrx Rat ethanol decreases expression ISO ATRX (Homo sapiens) 6480464 Ethanol results in decreased expression of ATRX mRNA CTD PMID:28986285 Atrx Rat flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of ATRX mRNA CTD PMID:24793618 Atrx Rat folic acid decreases expression ISO Atrx (Mus musculus) 6480464 Folic Acid results in decreased expression of ATRX mRNA CTD PMID:25629700 Atrx Rat fonofos increases methylation ISO ATRX (Homo sapiens) 6480464 Fonofos results in increased methylation of ATRX promoter CTD PMID:22847954 Atrx Rat formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of ATRX mRNA CTD PMID:18499655 Atrx Rat FR900359 affects phosphorylation ISO ATRX (Homo sapiens) 6480464 FR900359 affects the phosphorylation of ATRX protein CTD PMID:37730182 Atrx Rat fulvestrant multiple interactions ISO ATRX (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of ATRX gene CTD PMID:31601247 Atrx Rat geldanamycin increases expression ISO ATRX (Homo sapiens) 6480464 geldanamycin results in increased expression of ATRX mRNA CTD PMID:26705709 Atrx Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of ATRX mRNA CTD PMID:22061828 Atrx Rat hydrogen peroxide multiple interactions ISO ATRX (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ATRX protein CTD PMID:18951874 Atrx Rat hydrogen peroxide multiple interactions ISO Atrx (Mus musculus) 6480464 N-(oxo-5 more ... CTD PMID:31494107 Atrx Rat hydrogen peroxide increases expression ISO ATRX (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of ATRX mRNA CTD PMID:18951874 Atrx Rat idarubicin decreases expression ISO Atrx (Mus musculus) 6480464 Idarubicin results in decreased expression of ATRX mRNA CTD PMID:28973540 Atrx Rat idarubicin multiple interactions ISO Atrx (Mus musculus) 6480464 [Dexrazoxane co-treated with Idarubicin] results in increased expression of ATRX protein and Dexrazoxane inhibits the reaction [Idarubicin results in decreased expression of ATRX mRNA] CTD PMID:28973540 Atrx Rat irinotecan decreases expression ISO ATRX (Homo sapiens) 6480464 Irinotecan analog results in decreased expression of ATRX mRNA CTD PMID:18927307 Atrx Rat ivermectin decreases expression ISO ATRX (Homo sapiens) 6480464 Ivermectin results in decreased expression of ATRX protein CTD PMID:32959892 Atrx Rat josamycin affects response to substance ISO ATRX (Homo sapiens) 6480464 ATRX protein affects the susceptibility to Josamycin CTD PMID:31915244 Atrx Rat menadione affects expression ISO Atrx (Mus musculus) 6480464 Vitamin K 3 affects the expression of ATRX mRNA CTD PMID:20829426 Atrx Rat methoxychlor affects expression ISO Atrx (Mus musculus) 6480464 Methoxychlor affects the expression of ATRX mRNA CTD PMID:20829426 Atrx Rat methylparaben increases expression ISO ATRX (Homo sapiens) 6480464 methylparaben results in increased expression of ATRX mRNA CTD PMID:31745603 Atrx Rat miconazole decreases expression ISO Atrx (Mus musculus) 6480464 Miconazole results in decreased expression of ATRX mRNA CTD PMID:27462272 Atrx Rat mitomycin C affects response to substance ISO ATRX (Homo sapiens) 6480464 ATRX protein affects the susceptibility to Mitomycin CTD PMID:16217747 Atrx Rat morphine increases expression ISO Atrx (Mus musculus) 6480464 Morphine results in increased expression of ATRX mRNA CTD PMID:21955143 Atrx Rat N-ethyl-N-nitrosourea increases mutagenesis EXP 6480464 Ethylnitrosourea results in increased mutagenesis of ATRX gene CTD PMID:16495775 Atrx Rat naphthalene increases expression EXP 6480464 naphthalene analog results in increased expression of ATRX mRNA CTD PMID:24976557 Atrx Rat nicotine increases expression ISO ATRX (Homo sapiens) 6480464 Nicotine results in increased expression of ATRX mRNA CTD PMID:16949557 Atrx Rat nicotine decreases expression ISO Atrx (Mus musculus) 6480464 Nicotine results in decreased expression of ATRX mRNA CTD PMID:21955143 Atrx Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ATRX mRNA CTD PMID:25729387 Atrx Rat ozone multiple interactions ISO ATRX (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ATRX mRNA more ... CTD PMID:32699268 Atrx Rat paracetamol decreases expression ISO ATRX (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ATRX mRNA CTD PMID:21420995 Atrx Rat parathion increases methylation ISO ATRX (Homo sapiens) 6480464 Parathion results in increased methylation of ATRX promoter CTD PMID:22847954 Atrx Rat perfluorooctane-1-sulfonic acid decreases expression ISO ATRX (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of ATRX mRNA CTD PMID:27153767 Atrx Rat phenethyl isothiocyanate decreases expression EXP 6480464 phenethyl isothiocyanate results in decreased expression of ATRX mRNA CTD PMID:17616710 Atrx Rat phenobarbital decreases expression ISO Atrx (Mus musculus) 6480464 Phenobarbital results in decreased expression of ATRX mRNA CTD PMID:23091169 Atrx Rat potassium chromate decreases expression ISO ATRX (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of ATRX mRNA CTD PMID:22714537 Atrx Rat propiconazole decreases expression ISO Atrx (Mus musculus) 6480464 propiconazole results in decreased expression of ATRX mRNA CTD PMID:21278054 Atrx Rat resveratrol decreases expression EXP 6480464 Resveratrol results in decreased expression of ATRX mRNA CTD PMID:25905778 and PMID:33775663 Atrx Rat resveratrol multiple interactions ISO ATRX (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ATRX mRNA CTD PMID:23557933 Atrx Rat resveratrol decreases expression ISO ATRX (Homo sapiens) 6480464 resveratrol results in decreased expression of ATRX mRNA CTD PMID:25888808 Atrx Rat rifampicin increases expression ISO ATRX (Homo sapiens) 6480464 Rifampin results in increased expression of ATRX mRNA CTD PMID:24552687 Atrx Rat rotenone decreases expression ISO ATRX (Homo sapiens) 6480464 Rotenone results in decreased expression of ATRX mRNA CTD PMID:33512557 Atrx Rat SB 431542 multiple interactions ISO ATRX (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATRX mRNA CTD PMID:27188386 Atrx Rat selenium atom multiple interactions ISO ATRX (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA CTD PMID:19244175 Atrx Rat selenium atom decreases expression ISO ATRX (Homo sapiens) 6480464 Selenium results in decreased expression of ATRX mRNA CTD PMID:19244175 Atrx Rat silicon dioxide increases expression ISO Atrx (Mus musculus) 6480464 Silicon Dioxide results in increased expression of ATRX mRNA CTD PMID:19073995 Atrx Rat sodium arsenite multiple interactions ISO ATRX (Homo sapiens) 6480464 sodium arsenite promotes the reaction [ATRX protein binds to CAPRIN1 protein] CTD PMID:33939924 Atrx Rat sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of ATRX mRNA CTD PMID:22561333 Atrx Rat succimer multiple interactions ISO Atrx (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of ATRX mRNA and [Succimer co-treated with Magnetite Nanoparticles] affects the expression of ATRX mRNA CTD PMID:21641980 and PMID:26378955 Atrx Rat succimer multiple interactions ISO ATRX (Homo sapiens) 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ATRX mRNA CTD PMID:26378955 Atrx Rat sunitinib decreases expression ISO ATRX (Homo sapiens) 6480464 Sunitinib results in decreased expression of ATRX mRNA CTD PMID:31533062 Atrx Rat tamibarotene decreases expression ISO ATRX (Homo sapiens) 6480464 tamibarotene results in decreased expression of ATRX mRNA CTD PMID:15498508 Atrx Rat terbufos increases methylation ISO ATRX (Homo sapiens) 6480464 terbufos results in increased methylation of ATRX promoter CTD PMID:22847954 Atrx Rat testosterone enanthate increases expression ISO ATRX (Homo sapiens) 6480464 testosterone enanthate results in increased expression of ATRX mRNA CTD PMID:17440010 Atrx Rat tetrachloromethane affects expression ISO Atrx (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of ATRX mRNA CTD PMID:17484886 Atrx Rat thapsigargin increases expression ISO Atrx (Mus musculus) 6480464 Thapsigargin results in increased expression of ATRX protein CTD PMID:24648495 Atrx Rat theophylline multiple interactions ISO ATRX (Homo sapiens) 6480464 [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of ATRX protein CTD PMID:18951874 Atrx Rat thimerosal decreases expression ISO ATRX (Homo sapiens) 6480464 Thimerosal results in decreased expression of ATRX mRNA CTD PMID:27188386 Atrx Rat titanium dioxide decreases methylation ISO Atrx (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ATRX gene CTD PMID:35295148 Atrx Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ATRX mRNA CTD PMID:25729387 Atrx Rat topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of ATRX mRNA CTD PMID:25729387 Atrx Rat torcetrapib increases expression ISO ATRX (Homo sapiens) 6480464 torcetrapib results in increased expression of ATRX mRNA CTD PMID:23228038 Atrx Rat trichostatin A decreases expression ISO ATRX (Homo sapiens) 6480464 trichostatin A results in decreased expression of ATRX mRNA CTD PMID:24935251 and PMID:26272509 Atrx Rat trichostatin A multiple interactions ISO ATRX (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ATRX mRNA CTD PMID:27188386 Atrx Rat triphenyl phosphate affects expression ISO ATRX (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ATRX mRNA CTD PMID:37042841 Atrx Rat triptonide increases expression ISO Atrx (Mus musculus) 6480464 triptonide results in increased expression of ATRX mRNA CTD PMID:33045310 Atrx Rat troglitazone decreases expression ISO Atrx (Mus musculus) 6480464 troglitazone results in decreased expression of ATRX mRNA CTD PMID:28973697 Atrx Rat tungsten decreases expression ISO Atrx (Mus musculus) 6480464 Tungsten results in decreased expression of ATRX mRNA CTD PMID:30912803 Atrx Rat valproic acid decreases expression ISO Atrx (Mus musculus) 6480464 Valproic Acid analog results in decreased expression of ATRX mRNA and Valproic Acid results in decreased expression of ATRX mRNA CTD PMID:21427059 Atrx Rat valproic acid affects splicing EXP 6480464 Valproic Acid affects the splicing of ATRX mRNA CTD PMID:29427782 Atrx Rat valproic acid decreases expression ISO ATRX (Homo sapiens) 6480464 Valproic Acid results in decreased expression of ATRX mRNA CTD PMID:23179753 more ... Atrx Rat venlafaxine hydrochloride increases expression EXP 6480464 Venlafaxine Hydrochloride results in increased expression of ATRX mRNA CTD PMID:25423262 Atrx Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of ATRX mRNA CTD PMID:19015723 Atrx Rat vinclozolin increases methylation EXP 6480464 vinclozolin results in increased methylation of ATRX gene CTD PMID:31682807 Atrx Rat vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of ATRX mRNA CTD PMID:23034163 Atrx Rat vitamin E multiple interactions ISO ATRX (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA CTD PMID:19244175 Atrx Rat vitamin E decreases expression ISO ATRX (Homo sapiens) 6480464 Vitamin E results in decreased expression of ATRX mRNA CTD PMID:19244175 Atrx Rat vorinostat decreases expression ISO ATRX (Homo sapiens) 6480464 vorinostat results in decreased expression of ATRX mRNA CTD PMID:27188386 Atrx Rat zoledronic acid decreases expression ISO ATRX (Homo sapiens) 6480464 zoledronic acid results in decreased expression of ATRX mRNA CTD PMID:20977926
(+)-dexrazoxane (ISO) (+)-pilocarpine (EXP) (S)-nicotine (ISO) 1,2-dichloroethane (ISO) 1,2-dimethylhydrazine (ISO) 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine (EXP) 17beta-estradiol (EXP,ISO) 2,3',4,4',5-Pentachlorobiphenyl (ISO) 2,3,4,7,8-Pentachlorodibenzofuran (EXP) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,3,7,8-Tetrachlorodibenzofuran (EXP) 2,6-dinitrotoluene (EXP) 2-butoxyethanol (ISO) 3,4-methylenedioxymethamphetamine (ISO) 4-vinylcyclohexene dioxide (ISO) acrolein (ISO) acrylamide (EXP) aflatoxin B1 (ISO) Aflatoxin B2 alpha (ISO) all-trans-retinoic acid (ISO) alpha-pinene (ISO) ammonium chloride (EXP) antimycin A (ISO) antirheumatic drug (ISO) aristolochic acid A (ISO) benzene (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) Brevetoxin B (ISO) Brodifacoum (EXP) butanal (ISO) caffeine (ISO) carbon nanotube (ISO) chloroprene (EXP) clobetasol (ISO) clorgyline (ISO) cobalt dichloride (EXP) cocaine (EXP) coumarin (ISO) CU-O LINKAGE (ISO) cyclosporin A (ISO) cypermethrin (ISO) deoxynivalenol (ISO) diazinon (EXP,ISO) Dibutyl phosphate (ISO) diquat (ISO) diuron (EXP) dorsomorphin (ISO) doxorubicin (EXP,ISO) elemental selenium (ISO) Enterolactone (ISO) ethanol (ISO) flutamide (EXP) folic acid (ISO) fonofos (ISO) formaldehyde (EXP) FR900359 (ISO) fulvestrant (ISO) geldanamycin (ISO) gentamycin (EXP) hydrogen peroxide (ISO) idarubicin (ISO) irinotecan (ISO) ivermectin (ISO) josamycin (ISO) menadione (ISO) methoxychlor (ISO) methylparaben (ISO) miconazole (ISO) mitomycin C (ISO) morphine (ISO) N-ethyl-N-nitrosourea (EXP) naphthalene (EXP) nicotine (ISO) oxaliplatin (EXP) ozone (ISO) paracetamol (ISO) parathion (ISO) perfluorooctane-1-sulfonic acid (ISO) phenethyl isothiocyanate (EXP) phenobarbital (ISO) potassium chromate (ISO) propiconazole (ISO) resveratrol (EXP,ISO) rifampicin (ISO) rotenone (ISO) SB 431542 (ISO) selenium atom (ISO) silicon dioxide (ISO) sodium arsenite (ISO) sodium dichromate (EXP) succimer (ISO) sunitinib (ISO) tamibarotene (ISO) terbufos (ISO) testosterone enanthate (ISO) tetrachloromethane (ISO) thapsigargin (ISO) theophylline (ISO) thimerosal (ISO) titanium dioxide (ISO) topotecan (EXP) torcetrapib (ISO) trichostatin A (ISO) triphenyl phosphate (ISO) triptonide (ISO) troglitazone (ISO) tungsten (ISO) valproic acid (EXP,ISO) venlafaxine hydrochloride (EXP) vinclozolin (EXP) vitamin E (ISO) vorinostat (ISO) zoledronic acid (ISO)
Biological Process
biological_process (ND) cellular response to hydroxyurea (IEA,ISO,ISS) chromatin organization (IEA,ISO,ISS) chromatin remodeling (IEA,ISO,ISS) chromosome organization involved in meiotic cell cycle (IEA,ISO) DNA damage response (IEA) DNA damage response, signal transduction by p53 class mediator (IEA,ISO,ISS) DNA repair (IEA) forebrain development (IEA,ISO) meiotic spindle organization (IEA,ISO) multicellular organism growth (IEA,ISO) negative regulation of macromolecule biosynthetic process (IEA) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric (IEA,ISO) nucleosome assembly (IEA,ISO,ISS) positive regulation of nuclear cell cycle DNA replication (IEA,ISO,ISS) positive regulation of telomere maintenance (IEA,ISO,ISS) positive regulation of transcription by RNA polymerase II (IEA,ISO,ISS) post-embryonic forelimb morphogenesis (IEA,ISO) protein localization to chromosome, telomeric region (IEA,ISO) regulation of gene expression (IEA) replication fork processing (IEA,ISO,ISS) seminiferous tubule development (IEA,ISO) Sertoli cell development (IEA,ISO) spermatogenesis (IEA,ISO) subtelomeric heterochromatin formation (IEA,ISO,ISS) transcription by RNA polymerase II (IEA,ISO)
Cellular Component
chromosome (IEA) chromosome, subtelomeric region (IEA,ISO) chromosome, telomeric region (IEA,ISO,ISS) ciliary basal body (ISO) cilium (ISO) condensed chromosome, centromeric region (IEA,ISO) cytosol (ISO) heterochromatin (IEA,ISO) microtubule cytoskeleton (ISO) nuclear body (IEA,ISO) nuclear chromosome (IEA,ISO) nuclear speck (ISO) nucleoplasm (IEA,ISO) nucleus (IEA,ISO) pericentric heterochromatin (IEA,ISO) PML body (IEA,ISO)
1.
The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas.
Abedalthagafi M, etal., Mod Pathol. 2013 Nov;26(11):1425-32. doi: 10.1038/modpathol.2013.90. Epub 2013 Jun 14.
2.
Alpha-thalassemia intellectual disability: variable phenotypic expression among males with a recurrent nonsense mutation - c.109C>T (p.R37X).
Basehore MJ, etal., Clin Genet. 2014 May 7. doi: 10.1111/cge.12420.
3.
Novel ATRX gene damaging missense mutation c.6740A>C segregates with profound to severe intellectual deficiency without alpha thalassaemia.
Bouazzi H, etal., Indian J Med Res. 2016 Jan;143(1):43-8. doi: 10.4103/0971-5916.178589.
4.
Expression and prognostic impact of alpha thalassemia/mental retardation X-linked and death domain-associated protein in human lung cancer.
Buentzel J, etal., Medicine (Baltimore). 2019 Aug;98(31):e16712. doi: 10.1097/MD.0000000000016712.
5.
ATRX mRNA expression combined with IDH1/2 mutational status and Ki-67 expression refines the molecular classification of astrocytic tumors: evidence from the whole transcriptome sequencing of 169 samples samples.
Cai J, etal., Oncotarget. 2014 May 15;5(9):2551-61.
6.
Immunohistochemical Analysis of ATRX, IDH1 and p53 in Glioblastoma and Their Correlations with Patient Survival.
Chaurasia A, etal., J Korean Med Sci. 2016 Aug;31(8):1208-14. doi: 10.3346/jkms.2016.31.8.1208. Epub 2016 May 30.
7.
Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance.
Du M, etal., Lung Cancer. 2018 Jun;120:113-121. doi: 10.1016/j.lungcan.2018.04.008. Epub 2018 Apr 12.
8.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9.
A nonsense mutation of the ATRX gene causing mild mental retardation and epilepsy.
Guerrini R, etal., Ann Neurol. 2000 Jan;47(1):117-21.
10.
Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma.
Kannan K, etal., Oncotarget. 2012 Oct;3(10):1194-203.
11.
Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors.
Kim HS, etal., Anticancer Res. 2015 Jun;35(6):3501-10.
12.
Mutations of codon 2085 in the helicase domain of ATRX are recurrent and cause ATRX syndrome.
Lacoste C, etal., Clin Genet. 2013 Dec 1. doi: 10.1111/cge.12319.
13.
ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease.
Lee J, etal., Cell Death Differ. 2012 Jul;19(7):1109-16. doi: 10.1038/cdd.2011.196. Epub 2012 Jan 13.
14.
Comprehensive screening of alternative lengthening of telomeres phenotype and loss of ATRX expression in sarcomas.
Liau JY, etal., Mod Pathol. 2015 Dec;28(12):1545-54. doi: 10.1038/modpathol.2015.114. Epub 2015 Oct 2.
15.
[Mutation analysis for a Chinese family featuring X-linked alpha thalassemia/mental retardation syndrome].
Lin SB, etal., Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2013 Dec;30(6):654-8. doi: 10.3760/cma.j.issn.1003-9406.2013.06.004.
16.
Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.
Marinoni I, etal., Gastroenterology. 2014 Feb;146(2):453-60.e5. doi: 10.1053/j.gastro.2013.10.020. Epub 2013 Oct 19.
17.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
18.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
19.
Molecular cloning and characterization of annexin V-binding proteins with highly hydrophilic peptide structure.
Ohsawa K, etal., J Neurochem 1996 Jul;67(1):89-97.
20.
OMIM Disease Annotation Pipeline
OMIM Disease Annotation Pipeline
21.
Online Mendelian Inheritance in Man, OMIM (TM).
Online Mendelian Inheritance in Man, OMIM (TM).
22.
Decreased expression of the chromatin remodeler ATRX associates with melanoma progression.
Qadeer ZA, etal., J Invest Dermatol. 2014 Jun;134(6):1768-72. doi: 10.1038/jid.2014.45. Epub 2014 Jan 27.
23.
GOA pipeline
RGD automated data pipeline
24.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
25.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
26.
Comprehensive gene review and curation
RGD comprehensive gene curation
27.
Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly.
Solomon LA, etal., Hum Mol Genet. 2013 Dec 15;22(24):5015-25. doi: 10.1093/hmg/ddt351. Epub 2013 Jul 25.
28.
Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development.
Takeda H, etal., Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2057-65. doi: 10.1073/pnas.1603223113. Epub 2016 Mar 22.
29.
Localization of the chromatin remodelling protein, ATRX in the adult testis.
Tang P, etal., J Reprod Dev. 2011 Jun;57(3):317-21. Epub 2009 May 15.
30.
Loss of ATRX expression predicts worse prognosis in pulmonary carcinoid tumors.
Terra Md SBSP, etal., Hum Pathol. 2019 Dec;94:78-85. doi: 10.1016/j.humpath.2019.08.022. Epub 2019 Sep 6.
31.
XNP mutation in a large family with Juberg-Marsidi syndrome.
Villard L, etal., Nat Genet. 1996 Apr;12(4):359-60.
32.
Expanding phenotype of XNP mutations: mild to moderate mental retardation.
Yntema HG, etal., Am J Med Genet. 2002 Jul 1;110(3):243-7.
Atrx Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 X 74,916,548 - 75,062,880 (-) NCBI GRCr8 mRatBN7.2 X 70,850,981 - 70,997,330 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl X 70,850,981 - 70,997,330 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx X 72,359,919 - 72,506,253 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 X 75,860,229 - 76,006,565 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 X 73,423,392 - 73,569,729 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 X 76,820,110 - 76,979,155 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 76,820,329 - 76,979,115 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl X 76,692,970 - 76,708,878 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 X 77,469,497 - 77,515,204 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Rnor_5.0 X 55,943,493 - 56,101,756 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 X 93,903,794 - 94,051,337 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 X 94,034,366 - 94,057,029 (-) NCBI Celera X 72,164,814 - 72,309,854 (-) NCBI Celera Cytogenetic Map X q22 NCBI
ATRX Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 X 77,504,880 - 77,786,216 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl X 77,504,880 - 77,786,233 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 X 76,760,358 - 77,041,702 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 X 76,647,012 - 76,928,375 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera X 77,001,253 - 77,282,613 (-) NCBI Celera Cytogenetic Map X q21.1 NCBI HuRef X 70,349,443 - 70,629,029 (-) NCBI HuRef CHM1_1 X 76,653,073 - 76,934,420 (-) NCBI CHM1_1 T2T-CHM13v2.0 X 75,942,420 - 76,223,770 (-) NCBI T2T-CHM13v2.0
Atrx Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 X 104,841,221 - 104,972,978 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl X 104,841,221 - 104,973,009 (-) Ensembl GRCm39 Ensembl GRCm38 X 105,797,615 - 105,929,372 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl X 105,797,615 - 105,929,403 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 X 102,992,954 - 103,124,711 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 X 102,002,872 - 102,132,061 (-) NCBI MGSCv36 mm8 Celera X 92,651,743 - 92,783,324 (-) NCBI Celera Cytogenetic Map X D NCBI cM Map X 47.26 NCBI
Atrx Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955557 947,167 - 1,252,724 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955557 947,368 - 1,252,701 (-) NCBI ChiLan1.0 ChiLan1.0
ATRX Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 X 77,081,989 - 77,368,610 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 X 77,085,587 - 77,372,212 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 X 66,682,968 - 66,969,421 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 X 76,795,574 - 77,083,486 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl X 76,795,574 - 77,083,486 (-) Ensembl panpan1.1 panPan2
ATRX Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 X 59,772,067 - 60,107,016 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl X 59,774,585 - 60,106,980 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha X 50,787,446 - 51,120,278 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 X 61,011,471 - 61,270,437 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl X 61,011,677 - 61,270,443 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 X 58,719,357 - 59,051,934 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 X 60,325,606 - 60,661,270 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 X 59,917,163 - 60,249,816 (-) NCBI UU_Cfam_GSD_1.0
Atrx Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 X 42,229,198 - 42,451,804 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936683 2,495,959 - 2,718,620 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936683 2,496,307 - 2,718,539 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
ATRX Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl X 61,584,848 - 61,872,287 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 X 61,584,028 - 61,872,341 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 X 70,390,618 - 70,509,341 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
ATRX Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 X 66,449,830 - 66,737,220 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl X 66,448,449 - 66,737,164 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666067 14,772,636 - 15,066,083 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
.
Predicted Target Of
Count of predictions: 120 Count of miRNA genes: 99 Interacting mature miRNAs: 100 Transcripts: ENSRNOT00000042751, ENSRNOT00000045534 Prediction methods: Microtar, Miranda, Pita, Rnahybrid Result types: miRGate_prediction
61430 Cia18 Collagen induced arthritis QTL 18 3.1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 14843113 120568734 Rat 61431 Cia19 Collagen induced arthritis QTL 19 4.4 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) X 65612192 120568734 Rat 738035 Stresp1 Stress response QTL 1 4.96 0.000011 stress-related behavior trait (VT:0010451) defensive burying - coping X 41304447 112935181 Rat 1598837 Memor13 Memory QTL 13 3.2 exploratory behavior trait (VT:0010471) difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678) X 41052407 146860749 Rat
DXMgh10
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 70,871,973 - 70,872,106 (+) MAPPER mRatBN7.2 Rnor_6.0 X 76,841,244 - 76,841,376 NCBI Rnor6.0 Rnor_5.0 X 55,964,627 - 55,964,759 UniSTS Rnor5.0 RGSC_v3.4 X 93,924,589 - 93,924,722 RGD RGSC3.4 RGSC_v3.4 X 93,924,590 - 93,924,722 UniSTS RGSC3.4 RGSC_v3.1 X 93,998,022 - 93,998,155 RGD Celera X 72,185,808 - 72,185,937 UniSTS Cytogenetic Map X q31 UniSTS
RH142511
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 70,899,773 - 70,899,880 (+) MAPPER mRatBN7.2 Rnor_6.0 X 76,869,042 - 76,869,148 NCBI Rnor6.0 Rnor_5.0 X 55,992,425 - 55,992,531 UniSTS Rnor5.0 RGSC_v3.4 X 93,952,390 - 93,952,496 UniSTS RGSC3.4 Celera X 72,213,604 - 72,213,710 UniSTS Cytogenetic Map X q31 UniSTS
MARC_6759-6760:992007400:1
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 70,912,436 - 70,912,996 (+) MAPPER mRatBN7.2 Rnor_6.0 X 76,881,270 - 76,881,829 NCBI Rnor6.0 Rnor_6.0 X 76,666,051 - 76,666,610 NCBI Rnor6.0 Rnor_5.0 X 56,004,653 - 56,005,212 UniSTS Rnor5.0 Rnor_5.0 X 77,472,343 - 77,472,902 UniSTS Rnor5.0 RGSC_v3.4 X 93,965,086 - 93,965,645 UniSTS RGSC3.4 Celera X 72,226,236 - 72,226,795 UniSTS Cytogenetic Map X q31 UniSTS
GDB:596250
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 X 70,855,127 - 70,856,601 (+) MAPPER mRatBN7.2 Rnor_6.0 X 76,824,257 - 76,825,730 NCBI Rnor6.0 Rnor_5.0 X 55,947,640 - 55,949,113 UniSTS Rnor5.0 RGSC_v3.4 X 93,907,744 - 93,909,217 UniSTS RGSC3.4 Celera X 72,168,961 - 72,170,434 UniSTS Cytogenetic Map X q31 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
15
11
53
135
114
109
67
31
67
12
257
119
103
48
72
42
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000045534 ⟹ ENSRNOP00000051120
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl X 76,692,970 - 76,708,878 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000078997 ⟹ ENSRNOP00000071468
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 70,939,675 - 70,996,592 (-) Ensembl Rnor_6.0 Ensembl X 76,908,189 - 76,924,362 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000086752
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl X 76,857,656 - 76,865,244 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000087977 ⟹ ENSRNOP00000070457
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 70,850,981 - 70,956,139 (-) Ensembl Rnor_6.0 Ensembl X 76,823,010 - 76,925,195 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000088571
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl X 76,890,272 - 76,899,366 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000091284
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 70,850,981 - 70,997,330 (-) Ensembl Rnor_6.0 Ensembl X 76,820,329 - 76,979,115 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000095781 ⟹ ENSRNOP00000087702
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl X 70,850,981 - 70,997,330 (-) Ensembl
RefSeq Acc Id:
NM_001105757 ⟹ NP_001099227
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,880 (-) NCBI mRatBN7.2 X 70,850,981 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099458 ⟹ XP_038955386
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,162 (-) NCBI mRatBN7.2 X 70,850,981 - 70,996,607 (-) NCBI
RefSeq Acc Id:
XM_039099459 ⟹ XP_038955387
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,157 (-) NCBI mRatBN7.2 X 70,853,881 - 70,996,607 (-) NCBI
RefSeq Acc Id:
XM_039099460 ⟹ XP_038955388
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,157 (-) NCBI mRatBN7.2 X 70,853,881 - 70,996,607 (-) NCBI
RefSeq Acc Id:
XM_039099461 ⟹ XP_038955389
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,157 (-) NCBI mRatBN7.2 X 70,853,881 - 70,996,607 (-) NCBI
RefSeq Acc Id:
XM_039099462 ⟹ XP_038955390
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099464 ⟹ XP_038955392
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099465 ⟹ XP_038955393
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099466 ⟹ XP_038955394
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099467 ⟹ XP_038955395
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099468 ⟹ XP_038955396
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099469 ⟹ XP_038955397
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099470 ⟹ XP_038955398
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099471 ⟹ XP_038955399
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,298 (-) NCBI
RefSeq Acc Id:
XM_039099472 ⟹ XP_038955400
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099473 ⟹ XP_038955401
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI mRatBN7.2 X 70,853,881 - 70,997,330 (-) NCBI
RefSeq Acc Id:
XM_039099475 ⟹ XP_038955403
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,946,604 - 75,062,162 (-) NCBI mRatBN7.2 X 70,883,232 - 70,996,607 (-) NCBI
RefSeq Acc Id:
XM_063279780 ⟹ XP_063135850
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,877 (-) NCBI
RefSeq Acc Id:
XM_063279782 ⟹ XP_063135852
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,172 (-) NCBI
RefSeq Acc Id:
XM_063279783 ⟹ XP_063135853
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,165 (-) NCBI
RefSeq Acc Id:
XM_063279784 ⟹ XP_063135854
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI
RefSeq Acc Id:
XM_063279786 ⟹ XP_063135856
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,876 (-) NCBI
RefSeq Acc Id:
XM_063279787 ⟹ XP_063135857
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,175 (-) NCBI
RefSeq Acc Id:
XM_063279788 ⟹ XP_063135858
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 75,062,165 (-) NCBI
RefSeq Acc Id:
XM_063279789 ⟹ XP_063135859
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 X 74,916,548 - 74,982,507 (-) NCBI
Ensembl Acc Id:
ENSRNOP00000051120 ⟸ ENSRNOT00000045534
Ensembl Acc Id:
ENSRNOP00000070457 ⟸ ENSRNOT00000087977
Ensembl Acc Id:
ENSRNOP00000071468 ⟸ ENSRNOT00000078997
RefSeq Acc Id:
NP_001099227 ⟸ NM_001105757
- UniProtKB:
A0A8I6GFB1 (UniProtKB/TrEMBL), A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955386 ⟸ XM_039099458
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955401 ⟸ XM_039099473
- Peptide Label:
isoform X10
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955390 ⟸ XM_039099462
- Peptide Label:
isoform X6
- UniProtKB:
A0A8I6A4N1 (UniProtKB/TrEMBL), A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955397 ⟸ XM_039099469
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955398 ⟸ XM_039099470
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955396 ⟸ XM_039099468
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955400 ⟸ XM_039099472
- Peptide Label:
isoform X10
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955392 ⟸ XM_039099464
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955394 ⟸ XM_039099466
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955395 ⟸ XM_039099467
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955393 ⟸ XM_039099465
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955399 ⟸ XM_039099471
- Peptide Label:
isoform X8
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955389 ⟸ XM_039099461
- Peptide Label:
isoform X5
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955388 ⟸ XM_039099460
- Peptide Label:
isoform X4
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955387 ⟸ XM_039099459
- Peptide Label:
isoform X2
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_038955403 ⟸ XM_039099475
- Peptide Label:
isoform X13
Ensembl Acc Id:
ENSRNOP00000087702 ⟸ ENSRNOT00000095781
RefSeq Acc Id:
XP_063135850 ⟸ XM_063279780
- Peptide Label:
isoform X3
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135856 ⟸ XM_063279786
- Peptide Label:
isoform X10
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135854 ⟸ XM_063279784
- Peptide Label:
isoform X10
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135857 ⟸ XM_063279787
- Peptide Label:
isoform X11
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135852 ⟸ XM_063279782
- Peptide Label:
isoform X7
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135858 ⟸ XM_063279788
- Peptide Label:
isoform X12
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135853 ⟸ XM_063279783
- Peptide Label:
isoform X9
- UniProtKB:
A0A0G2JXZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135859 ⟸ XM_063279789
- Peptide Label:
isoform X14
RGD ID: 13701901 Promoter ID: EPDNEW_R12421 Type: initiation region Name: Atrx_1 Description: ATRX, chromatin remodeler SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 X 76,979,115 - 76,979,175 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2021-03-09
Atrx
ATRX, chromatin remodeler
LOC103690008
transcriptional regulator ATRX-like
Data merged from RGD:9140280
737654 PROVISIONAL
2016-06-01
Atrx
ATRX, chromatin remodeler
Atrx
alpha thalassemia/mental retardation syndrome X-linked
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2014-08-25
LOC103690008
transcriptional regulator ATRX-like
Symbol and Name status set to provisional
70820 PROVISIONAL
2011-07-28
Atrx
alpha thalassemia/mental retardation syndrome X-linked
Atrx
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2008-09-25
Atrx
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
Nomenclature updated to reflect human and mouse nomenclature
1299863 APPROVED
2005-01-20
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae)
Name updated
1299863 APPROVED
2002-08-07
Atrx
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S.cerevisiae)
Symbol and Name status set to provisional
70820 PROVISIONAL
Note Type
Note
Reference
gene_homology
high homology with human X-linked Helicase2 (XH2)
631943
