Cxadr (CXADR cell adhesion molecule) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Cxadr (CXADR cell adhesion molecule) Rattus norvegicus
Analyze
Symbol: Cxadr
Name: CXADR cell adhesion molecule (Ensembl:CXADR, Ig-like cell adhesion molecule)
RGD ID: 619794
Description: Predicted to enable several functions, including PDZ domain binding activity; beta-catenin binding activity; and connexin binding activity. Predicted to be involved in several processes, including AV node cell-bundle of His cell adhesion involved in cell communication; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and neutrophil chemotaxis. Predicted to act upstream of or within negative regulation of cardiac muscle cell proliferation. Located in bicellular tight junction and neuron projection. Orthologous to human CXADR (CXADR Ig-like cell adhesion molecule); PARTICIPATES IN myocarditis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CAR; Car1; coxsackie virus and adenovirus receptor; coxsackievirus and adenovirus receptor homolog; CXADR, Ig-like cell adhesion molecule; MGC109536; rCAR
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81130,469,778 - 30,516,990 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1130,469,526 - 30,516,988 (+)EnsemblGRCr8
mRatBN7.21116,982,864 - 17,030,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1116,982,860 - 17,030,046 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1125,620,930 - 25,668,242 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01118,350,955 - 18,398,261 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01117,511,443 - 17,559,008 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01116,826,269 - 16,873,564 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,826,399 - 16,873,562 (+)Ensemblrn6Rnor6.0
Rnor_5.01120,480,930 - 20,528,211 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41117,193,505 - 17,241,549 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1116,973,781 - 17,020,940 (+)NCBICelera
RGSC_v3.11117,193,575 - 17,227,857 (+)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bosentan  (ISO)
butanal  (ISO)
butyric acid  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (ISO)
clothianidin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (EXP)
diquat  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enniatin  (EXP)
epoxiconazole  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methoxychlor  (EXP)
mifepristone  (EXP)
mitoxantrone  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (ISO)
potassium iodide  (EXP)
propiconazole  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rimonabant  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
valproic acid  (EXP,ISO)
valsartan  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Expression of coxsackie adenovirus receptor and alphav-integrin does not correlate with adenovector targeting in vivo indicating anatomical vector barriers. Fechner H, etal., Gene Ther 1999 Sep;6(9):1520-35.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Coxsackievirus and adenovirus receptor, a tight junction membrane protein, is expressed in glomerular podocytes in the kidney. Nagai M, etal., Lab Invest 2003 Jun;83(6):901-11.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. CAR-associated vesicular transport of an adenovirus in motor neuron axons. Salinas S, etal., PLoS Pathog. 2009 May;5(5):e1000442. doi: 10.1371/journal.ppat.1000442. Epub 2009 May 22.
10. Podocin participates in the assembly of tight junctions between foot processes in nephrotic podocytes. Shono A, etal., J Am Soc Nephrol. 2007 Sep;18(9):2525-33. Epub 2007 Aug 5.
Additional References at PubMed
PMID:9096397   PMID:10814828   PMID:11316797   PMID:11734628   PMID:12297051   PMID:12477932   PMID:12869515   PMID:14624362   PMID:14978041   PMID:15057822   PMID:15304526   PMID:15364909  
PMID:15489334   PMID:15533241   PMID:15800062   PMID:15864812   PMID:16079292   PMID:16410001   PMID:16543498   PMID:16678988   PMID:16780588   PMID:17359973   PMID:17538635   PMID:17690169  
PMID:18205224   PMID:18636119   PMID:20235596   PMID:20361046   PMID:20813954   PMID:21269662   PMID:22003382   PMID:22875787   PMID:24057874   PMID:25468996   PMID:25497012  


Genomics

Comparative Map Data
Cxadr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81130,469,778 - 30,516,990 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1130,469,526 - 30,516,988 (+)EnsemblGRCr8
mRatBN7.21116,982,864 - 17,030,078 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1116,982,860 - 17,030,046 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1125,620,930 - 25,668,242 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01118,350,955 - 18,398,261 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01117,511,443 - 17,559,008 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01116,826,269 - 16,873,564 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,826,399 - 16,873,562 (+)Ensemblrn6Rnor6.0
Rnor_5.01120,480,930 - 20,528,211 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41117,193,505 - 17,241,549 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1116,973,781 - 17,020,940 (+)NCBICelera
RGSC_v3.11117,193,575 - 17,227,857 (+)NCBI
Cytogenetic Map11q11NCBI
CXADR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382117,513,043 - 17,636,262 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2117,512,971 - 17,593,579 (+)Ensemblhg38GRCh38
GRCh372118,885,361 - 18,965,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362117,807,201 - 17,861,147 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342117,807,200 - 17,861,135NCBI
Celera214,060,105 - 4,114,040 (+)NCBICelera
Cytogenetic Map21q21.1NCBI
HuRef214,271,028 - 4,351,637 (+)NCBIHuRef
CHM1_12118,445,887 - 18,526,468 (+)NCBICHM1_1
T2T-CHM13v2.02115,868,092 - 15,991,279 (+)NCBIT2T-CHM13v2.0
Cxadr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391678,098,114 - 78,156,673 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1678,098,377 - 78,156,662 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381678,301,226 - 78,359,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1678,301,489 - 78,359,774 (+)Ensemblmm10GRCm38
MGSCv371678,301,936 - 78,360,030 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361678,184,283 - 78,223,344 (+)NCBIMGSCv36mm8
Celera1678,531,603 - 78,582,585 (+)NCBICelera
Cytogenetic Map16C3.1NCBI
cM Map1645.28NCBI
Cxadr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540718,867,797 - 18,907,331 (+)Ensembl
ChiLan1.0NW_00495540718,894,853 - 18,927,129 (+)NCBIChiLan1.0ChiLan1.0
CXADR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22214,006,536 - 14,089,608 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1218,834,367 - 8,914,891 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0214,246,779 - 4,367,369 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12117,637,510 - 17,693,324 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2117,636,952 - 17,693,324 (+)EnsemblpanPan2panpan1.1
CXADR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13114,021,292 - 14,079,049 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3114,021,303 - 14,078,847 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3114,040,422 - 14,099,214 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03114,054,721 - 14,113,513 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3114,055,183 - 14,113,306 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13114,057,180 - 14,115,931 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03114,060,916 - 14,121,453 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03114,461,638 - 14,520,275 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cxadr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497115,051,698 - 15,094,341 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365059,971,118 - 10,032,238 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365059,971,393 - 10,032,238 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXADR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13182,134,566 - 182,185,950 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113182,134,416 - 182,185,977 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213192,284,884 - 192,305,700 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXADR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1275,027,499 - 75,078,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl275,001,562 - 75,078,033 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605078,908,252 - 78,986,846 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cxadr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247455,900,886 - 5,958,765 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247455,900,933 - 5,954,584 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Cxadr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1463,727,040 - 63,742,827 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cxadr
361 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:47
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000050701
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11381815448818154Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
RH137702  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21117,020,309 - 17,020,525 (+)MAPPERmRatBN7.2
Rnor_6.01116,863,796 - 16,864,011NCBIRnor6.0
Rnor_5.01120,518,443 - 20,518,658UniSTSRnor5.0
RGSC_v3.41117,231,781 - 17,231,996UniSTSRGSC3.4
Celera1117,011,172 - 17,011,387UniSTS
RH 3.4 Map1165.2UniSTS
Cytogenetic Map11q11UniSTS
AU049654  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21117,014,818 - 17,014,969 (+)MAPPERmRatBN7.2
Rnor_6.01116,858,308 - 16,858,458NCBIRnor6.0
Rnor_5.01120,512,955 - 20,513,105UniSTSRnor5.0
RGSC_v3.41117,226,292 - 17,226,442UniSTSRGSC3.4
Celera1117,005,683 - 17,005,833UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 83 59 6 347 183 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000050701   ⟹   ENSRNOP00000041873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1130,469,526 - 30,516,988 (+)Ensembl
mRatBN7.2 Ensembl1116,982,860 - 17,030,046 (+)Ensembl
Rnor_6.0 Ensembl1116,826,399 - 16,873,562 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094570   ⟹   ENSRNOP00000091602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1130,469,526 - 30,496,379 (+)Ensembl
mRatBN7.2 Ensembl1116,982,860 - 17,009,467 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165577   ⟹   ENSRNOP00000100397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1130,469,778 - 30,507,531 (+)Ensembl
RefSeq Acc Id: NM_001399207   ⟹   NP_001386136
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81130,469,778 - 30,507,531 (+)NCBI
mRatBN7.21116,982,864 - 17,020,619 (+)NCBI
RefSeq Acc Id: NM_053570   ⟹   NP_446022
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81130,469,778 - 30,516,990 (+)NCBI
mRatBN7.21116,982,864 - 17,030,078 (+)NCBI
Rnor_6.01116,826,399 - 16,873,564 (+)NCBI
Rnor_5.01120,480,930 - 20,528,211 (+)NCBI
RGSC_v3.41117,193,505 - 17,241,549 (+)RGD
Celera1116,973,781 - 17,020,940 (+)RGD
Sequence:
RefSeq Acc Id: NP_446022   ⟸   NM_053570
- Peptide Label: isoform 2 precursor
- UniProtKB: A6JL34 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000041873   ⟸   ENSRNOT00000050701
Ensembl Acc Id: ENSRNOP00000091602   ⟸   ENSRNOT00000094570
RefSeq Acc Id: NP_001386136   ⟸   NM_001399207
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9R066 (UniProtKB/Swiss-Prot),   Q5M817 (UniProtKB/Swiss-Prot),   Q9R067 (UniProtKB/Swiss-Prot),   A6JL35 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100397   ⟸   ENSRNOT00000165577
Protein Domains
Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R066-F1-model_v2 AlphaFold Q9R066 1-365 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698007
Promoter ID:EPDNEW_R8532
Type:initiation region
Name:Cxadr_1
Description:CXADR, Ig-like cell adhesion molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01116,826,386 - 16,826,446EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619794 AgrOrtholog
BioCyc Gene G2FUF-22139 BioCyc
Ensembl Genes ENSRNOG00000001557 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000050701 ENTREZGENE
  ENSRNOT00000050701.4 UniProtKB/Swiss-Prot
  ENSRNOT00000165577 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7324723 IMAGE-MGC_LOAD
InterPro EJ_Adhesion_Regulator UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
KEGG Report rno:89843 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109536 IMAGE-MGC_LOAD
NCBI Gene 89843 ENTREZGENE
PANTHER COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR UniProtKB/Swiss-Prot
  COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR-RELATED UniProtKB/Swiss-Prot
Pfam Ig_2 UniProtKB/Swiss-Prot
  V-set UniProtKB/Swiss-Prot
PhenoGen Cxadr PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001557 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot
UniProt A0A8I6AST4_RAT UniProtKB/TrEMBL
  A6JL34 ENTREZGENE, UniProtKB/TrEMBL
  A6JL35 ENTREZGENE, UniProtKB/TrEMBL
  CXAR_RAT UniProtKB/Swiss-Prot
  Q5M817 ENTREZGENE
  Q9R066 ENTREZGENE
  Q9R067 ENTREZGENE
UniProt Secondary Q5M817 UniProtKB/Swiss-Prot
  Q9R067 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-11-13 Cxadr  CXADR cell adhesion molecule  Cxadr  CXADR, Ig-like cell adhesion molecule  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-05-05 Cxadr  CXADR, Ig-like cell adhesion molecule  Cxadr  coxsackie virus and adenovirus receptor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cxadr  coxsackie virus and adenovirus receptor      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Cxadr  coxsackie virus and adenovirus receptor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in podocytes and polarized epithelial cells 1299248
gene_function may be a barrier for macromolecule and ion movement across membranes in polarized epithelial cells 1299248