Stx7 (syntaxin 7) - Rat Genome Database

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Gene: Stx7 (syntaxin 7) Rattus norvegicus
Analyze
Symbol: Stx7
Name: syntaxin 7
RGD ID: 619747
Description: Enables SNAP receptor activity and SNARE binding activity. Involved in endosome to lysosome transport and vesicle fusion. Located in late endosome membrane and lysosomal membrane. Part of SNARE complex. Is active in synaptic vesicle membrane. Orthologous to human STX7 (syntaxin 7); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100910446; syntaxin-7; syntaxin-7-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,016,330 - 23,056,579 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl123,016,336 - 23,056,465 (-)EnsemblGRCr8
mRatBN7.2121,197,075 - 21,237,320 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,197,075 - 21,237,279 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx120,973,496 - 21,014,331 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,973,523 - 27,014,359 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,173,353 - 21,214,086 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,241,655 - 22,281,850 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,241,661 - 22,281,788 (-)Ensemblrn6Rnor6.0
Rnor_5.0123,721,812 - 23,762,002 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4121,721,897 - 21,762,024 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera119,947,867 - 19,987,994 (-)NCBICelera
RGSC_v3.1121,724,841 - 21,764,969 (-)NCBI
Cytogenetic Map1p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
chlorohydrocarbon  (EXP)
ciglitazone  (ISO)
coumestrol  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (ISO)
finasteride  (EXP)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
GSK-J4  (ISO)
haloperidol  (EXP)
indole-3-methanol  (EXP)
ivermectin  (ISO)
LY294002  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methoxychlor  (EXP)
N(4)-hydroxycytidine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nitrates  (ISO)
ochratoxin A  (ISO)
paracetamol  (EXP)
perfluorooctanoic acid  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Crystal structure of the endosomal SNARE complex reveals common structural principles of all SNAREs. Antonin W, etal., Nat Struct Biol 2002 Feb;9(2):107-11.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. Pryor PR, etal., EMBO Rep. 2004 Jun;5(6):590-5. Epub 2004 May 7.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Mammalian late vacuole protein sorting orthologues participate in early endosomal fusion and interact with the cytoskeleton. Richardson SC, etal., Mol Biol Cell 2004 Mar;15(3):1197-210. Epub 2003 Dec 10.
12. Molecular anatomy of a trafficking organelle. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
13. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
14. Syntaxin 7, a novel syntaxin member associated with the early endosomal compartment. Wong SH, etal., J Biol Chem 1998 Jan 2;273(1):375-80.
Additional References at PubMed
PMID:10564279   PMID:11101518   PMID:12477932   PMID:17897319   PMID:18321981   PMID:18570918   PMID:18980942   PMID:19549681   PMID:20170677   PMID:20458337   PMID:21438968   PMID:21700703  
PMID:22871113   PMID:23376485   PMID:24550300  


Genomics

Comparative Map Data
Stx7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8123,016,330 - 23,056,579 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl123,016,336 - 23,056,465 (-)EnsemblGRCr8
mRatBN7.2121,197,075 - 21,237,320 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl121,197,075 - 21,237,279 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx120,973,496 - 21,014,331 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,973,523 - 27,014,359 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0121,173,353 - 21,214,086 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0122,241,655 - 22,281,850 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl122,241,661 - 22,281,788 (-)Ensemblrn6Rnor6.0
Rnor_5.0123,721,812 - 23,762,002 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4121,721,897 - 21,762,024 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera119,947,867 - 19,987,994 (-)NCBICelera
RGSC_v3.1121,724,841 - 21,764,969 (-)NCBI
Cytogenetic Map1p12NCBI
STX7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386132,445,867 - 132,513,472 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6132,445,867 - 132,513,999 (-)Ensemblhg38GRCh38
GRCh376132,767,006 - 132,834,611 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,822,848 - 132,875,859 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346132,822,847 - 132,875,859NCBI
Celera6133,525,518 - 133,581,174 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6130,353,519 - 130,409,169 (-)NCBIHuRef
CHM1_16133,042,339 - 133,098,018 (-)NCBICHM1_1
T2T-CHM13v2.06133,640,859 - 133,708,445 (-)NCBIT2T-CHM13v2.0
Stx7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391024,025,182 - 24,064,859 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1024,025,200 - 24,066,120 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381024,149,289 - 24,188,961 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1024,149,302 - 24,190,222 (+)Ensemblmm10GRCm38
MGSCv371023,869,123 - 23,908,765 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361023,838,776 - 23,878,375 (+)NCBIMGSCv36mm8
Celera1025,082,517 - 25,122,173 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.45NCBI
Stx7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543612,931,666 - 12,975,766 (-)Ensembl
ChiLan1.0NW_00495543612,928,274 - 12,975,745 (-)NCBIChiLan1.0ChiLan1.0
STX7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25152,440,392 - 152,495,586 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16150,345,389 - 150,402,661 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06130,232,041 - 130,289,326 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16134,342,305 - 134,397,533 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6134,342,304 - 134,398,215 (-)EnsemblpanPan2panpan1.1
STX7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,544,283 - 25,607,179 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,546,596 - 25,607,231 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha126,531,632 - 26,594,249 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0125,455,483 - 25,518,496 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl125,458,138 - 25,518,571 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1125,501,729 - 25,564,656 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0125,400,189 - 25,462,818 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,663,904 - 25,726,563 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Stx7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946120,685,451 - 120,733,071 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936560464,617 - 513,009 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936560464,667 - 512,322 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STX7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,184,947 - 31,235,865 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1131,184,905 - 31,237,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2134,705,635 - 34,757,859 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STX7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11341,029,992 - 41,086,589 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1341,030,073 - 41,088,308 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604013,220,150 - 13,275,468 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Stx7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247536,514,056 - 6,547,480 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247536,511,516 - 6,554,406 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Stx7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12210,238,514 - 210,278,071 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Stx7
263 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:144
Count of miRNA genes:104
Interacting mature miRNAs:127
Transcripts:ENSRNOT00000021318
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
BF403910  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2121,204,403 - 21,204,523 (+)MAPPERmRatBN7.2
Rnor_6.0123,549,705 - 23,549,824NCBIRnor6.0
Rnor_6.0122,248,984 - 22,249,103NCBIRnor6.0
Rnor_5.0125,019,330 - 25,019,449UniSTSRnor5.0
Rnor_5.0123,729,141 - 23,729,260UniSTSRnor5.0
RGSC_v3.4121,729,220 - 21,729,339UniSTSRGSC3.4
Celera119,955,195 - 19,955,314UniSTS
RH 3.4 Map1208.7UniSTS
Cytogenetic Map1p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000021318   ⟹   ENSRNOP00000021318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl123,016,336 - 23,056,465 (-)Ensembl
mRatBN7.2 Ensembl121,197,078 - 21,237,279 (-)Ensembl
Rnor_6.0 Ensembl122,241,661 - 22,281,788 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072943   ⟹   ENSRNOP00000065991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl121,197,075 - 21,209,264 (-)Ensembl
Rnor_6.0 Ensembl123,543,426 - 23,556,241 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081804   ⟹   ENSRNOP00000073994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl123,016,336 - 23,045,172 (-)Ensembl
mRatBN7.2 Ensembl121,197,075 - 21,226,124 (-)Ensembl
Rnor_6.0 Ensembl122,242,718 - 22,269,831 (-)Ensembl
RefSeq Acc Id: NM_021869   ⟹   NP_068641
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,016,336 - 23,056,465 (-)NCBI
mRatBN7.2121,197,081 - 21,237,213 (-)NCBI
Rnor_6.0122,241,661 - 22,281,788 (-)NCBI
Rnor_5.0123,721,812 - 23,762,002 (-)NCBI
RGSC_v3.4121,721,897 - 21,762,024 (-)RGD
Celera119,947,867 - 19,987,994 (-)RGD
Sequence:
RefSeq Acc Id: XM_017589644   ⟹   XP_017445133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,016,330 - 23,056,579 (-)NCBI
mRatBN7.2121,197,075 - 21,237,320 (-)NCBI
Rnor_6.0122,241,655 - 22,281,850 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089032   ⟹   XP_038944960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8123,016,330 - 23,056,520 (-)NCBI
mRatBN7.2121,197,085 - 21,237,268 (-)NCBI
RefSeq Acc Id: NP_068641   ⟸   NM_021869
- UniProtKB: Q5U337 (UniProtKB/Swiss-Prot),   O70257 (UniProtKB/Swiss-Prot),   A6JUL4 (UniProtKB/TrEMBL),   A0A0G2K6Y9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445133   ⟸   XM_017589644
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000021318   ⟸   ENSRNOT00000021318
Ensembl Acc Id: ENSRNOP00000073994   ⟸   ENSRNOT00000081804
RefSeq Acc Id: XP_038944960   ⟸   XM_039089032
- Peptide Label: isoform X1
- UniProtKB: O70257 (UniProtKB/Swiss-Prot),   Q5U337 (UniProtKB/Swiss-Prot),   A6JUL4 (UniProtKB/TrEMBL),   A0A0G2K6Y9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000065991   ⟸   ENSRNOT00000072943
Protein Domains
Syntaxin N-terminal   t-SNARE coiled-coil homology

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R930-F1-model_v2 AlphaFold M0R930 1-252 view protein structure
AF-O70257-F1-model_v2 AlphaFold O70257 1-261 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689529
Promoter ID:EPDNEW_R53
Type:initiation region
Name:Stx7_1
Description:syntaxin 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0122,281,848 - 22,281,908EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619747 AgrOrtholog
BioCyc Gene G2FUF-62103 BioCyc
Ensembl Genes ENSRNOG00000015670 Ensembl, ENTREZGENE
  ENSRNOG00000048248 Ensembl
Ensembl Transcript ENSRNOT00000021318 ENTREZGENE
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot
  1.20.58.70 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7193349 IMAGE-MGC_LOAD
InterPro SNARE UniProtKB/Swiss-Prot
  Syntaxin UniProtKB/Swiss-Prot
  Syntaxin/epimorphin_CS UniProtKB/Swiss-Prot
  Syntaxin_N UniProtKB/Swiss-Prot
  T_SNARE_dom UniProtKB/Swiss-Prot
KEGG Report rno:60466 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93455 IMAGE-MGC_LOAD
NCBI Gene 60466 ENTREZGENE
PANTHER PTHR19957 UniProtKB/Swiss-Prot
  SYNTAXIN-7 UniProtKB/Swiss-Prot
Pfam SNARE UniProtKB/Swiss-Prot
  Syntaxin_2 UniProtKB/Swiss-Prot
PhenoGen Stx7 PhenoGen
PROSITE SYNTAXIN UniProtKB/Swiss-Prot
  T_SNARE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015670 RatGTEx
  ENSRNOG00000048248 RatGTEx
SMART SynN UniProtKB/Swiss-Prot
  t_SNARE UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47661 UniProtKB/Swiss-Prot
UniProt A0A0G2K6Y9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QAN2_RAT UniProtKB/TrEMBL
  A6JUL2_RAT UniProtKB/TrEMBL
  A6JUL4 ENTREZGENE, UniProtKB/TrEMBL
  O70257 ENTREZGENE
  Q5U337 ENTREZGENE
  STX7_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q5U337 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Stx7  syntaxin 7  LOC100910446  syntaxin-7-like  Data merged from RGD:6498726 737654 PROVISIONAL
2012-07-05 LOC100910446  syntaxin-7-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-02-26 Stx7  syntaxin 7      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Stx7  syntaxin 7      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA widely expressed in all tissues 634188
gene_process involved with vesicle docking and fusion events with membrane 634188