Gene:	Lcp2 ( Rattus norvegicus ) lymphocyte cytosolic protein 2
Description:	hematopoietic cell-specific protein; may mediate signaling events in multiple cell types in the immune system
Synonyms:	Slp76; lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD);  (details...)
ArrayIDs:	6187993; 5839280; 6733468; 5826940; 5780965; 6302491; 5621228; 6445757; 5847042; 1370090_at; 1390797_at; 6680781; 5869981; rc_AA892316_at; rc_AI060017_at; 5976129; 5801380; 6515576; 5767074; 5725168; 6695862; 5852754; 6381829; 5930099; 6162743; 6299575; 6450781; 5712073;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: LCP2     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Lcp2     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Lcp2 genome assembly 3.1 10 19021186 - 19066146     Rat Celera Assembly 10 18275491 - 18322327     RGSC genome assembly v3.4 10 19019978 - 19066744     Cytogenetic 10 q12 Mus musculus Lcp2 Mouse genome assembly build 36.1 11 33947201 - 33992280     Cytogenetic 11 11 A4 Homo sapiens LCP2 human genome assembly 5 169607666 - 169657400     Human genome assembly build 36.2 5 169607666 - 169657400     Cytogenetic 5 q33.1-qter   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology protein binding (details...)
Biological Process	Gene Ontology cytokine secretion,  mast cell activation (details...)
Cellular Component	Gene Ontology cytosol (details...)
Physical interaction	Note Reference interacts with the Grb2 adapter protein in the mast cells 724419
External Links
Databases	DATABASE ID SOURCE Ensembl Protein: ENSRNOP00000050879 IPI Ensembl Protein: ENSRNOP00000007784 IPI IPI: IPI00200653 IPI IPI: IPI00569987 IPI Entrez Gene: Lcp2 ENTREZGENE IMAGE_CLONE: IMAGE:7387128 IMAGE-MGC_LOAD UNIPARC: UPI0001B7A243 IPI UNIPARC: UPI0001B7A244 IPI MGC_CLONE: MGC:112603 IMAGE-MGC_LOAD KEGG Report: rno:155918 ENTREZGENE Ensembl Genes: ENSRNOG00000005620 IPI UniProt: Q920L0_RAT IPI HomoloGene Group ID: 4065 ENTREZGENE Germonline: 619743 KEGG Pathway: 04664 ENTREZGENE KEGG Pathway: 04650 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE
Sequences	Nucleotide: NM_130421 Get FASTA Search GEO Profiles Nucleotide: CH473948 Get FASTA Search GEO Profiles Nucleotide: AB072980 Get FASTA Search GEO Profiles Nucleotide: BC100066 Get FASTA Search GEO Profiles (View all 4 Nucleotide Accessions) Protein: NP_569105 Get FASTA Protein: EDM04082 Get FASTA Protein: EDM04084 Get FASTA Protein: BAB71779 Get FASTA Protein: AAI00067 Get FASTA Protein: Q920L0 Get FASTA Protein: EDM04083 Get FASTA (View all 7 Protein Accessions)
Clusters	UniGene: 1057
References
Curated References	5 references in RGD related to Lcp2
Other References	2 other references at PubMed related to Lcp2
Database Information
RGD ID	619743
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 20-JAN-05: Lcp2 lymphocyte cytosolic protein 2 lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) APPROVED Name updated 1299863 07-AUG-02: Lcp2 lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD) PROVISIONAL Symbol and Name status set to provisional 70820