Rab1a (RAB1A, member RAS oncogene family) - Rat Genome Database

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Gene: Rab1a (RAB1A, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab1a
Name: RAB1A, member RAS oncogene family
RGD ID: 619736
Description: Enables GTP binding activity. Involved in endocytosis and vesicle transport along microtubule. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in several cellular components, including Golgi membrane; early endosome; and neuronal cell body. Is active in presynapse. Orthologous to human RAB1A (RAB1A, member RAS oncogene family); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ac2-048; Rab1; RAB1, member RAS oncogene family; Rab1r; ras-related protein; ras-related protein Rab-1A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rab1-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,623,582 - 98,648,766 (+)NCBIGRCr8
mRatBN7.21494,422,219 - 94,448,799 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,415,275 - 94,448,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1498,769,042 - 98,794,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,009,313 - 100,034,363 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,476,690 - 96,501,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,475,082 - 104,500,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,475,082 - 104,501,020 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,208,420 - 104,235,377 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414100,973,039 - 101,027,893 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114100,992,249 - 101,047,101 (+)NCBI
Celera1493,445,267 - 93,470,406 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Rab1aRatdilated cardiomyopathy  ISSRab1a (Mus musculus)13592920 MouseDO 

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Object Symbol
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Original Reference(s)
Rab1aRat(-)-epigallocatechin 3-gallate multiple interactionsISORAB1A (Homo sapiens)6480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RAB1A mRNACTDPMID:22079256
Rab1aRat(1->4)-beta-D-glucan multiple interactionsISORab1a (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RAB1A mRNACTDPMID:36331819
Rab1aRat17alpha-ethynylestradiol affects expressionISORab1a (Mus musculus)6480464Ethinyl Estradiol affects the expression of RAB1A mRNACTDPMID:17555576
Rab1aRat17alpha-ethynylestradiol increases expressionISORab1a (Mus musculus)6480464Ethinyl Estradiol results in increased expression of RAB1A mRNACTDPMID:17942748
Rab1aRat17beta-estradiol increases expressionISORab1a (Mus musculus)6480464Estradiol results in increased expression of RAB1A mRNACTDPMID:39298647
Rab1aRat2,3',4,4',5-Pentachlorobiphenyl increases expressionISORab1a (Mus musculus)64804642 more ...CTDPMID:31388691
Rab1aRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORab1a (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RAB1A mRNACTDPMID:21570461
Rab1aRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of RAB1A mRNACTDPMID:33387578 and PMID:34747641
Rab1aRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORab1a (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of RAB1A mRNACTDPMID:27913140
Rab1aRat2,6-dimethoxyphenol multiple interactionsISORAB1A (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of and affects the localization of RAB1A proteinCTDPMID:38598786
Rab1aRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of RAB1A mRNACTDPMID:21346803
Rab1aRat2-bromohexadecanoic acid multiple interactionsISORAB1A (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of RAB1A protein]CTDPMID:38195004
Rab1aRat2-hydroxypropanoic acid decreases expressionISORAB1A (Homo sapiens)6480464Lactic Acid results in decreased expression of RAB1A mRNACTDPMID:30851411
Rab1aRat3H-1,2-dithiole-3-thione decreases expressionEXP 64804641 and 2-dithiol-3-thione results in decreased expression of RAB1A mRNACTDPMID:19162173
Rab1aRat4,4'-sulfonyldiphenol increases expressionISORab1a (Mus musculus)6480464bisphenol S results in increased expression of RAB1A mRNACTDPMID:39298647
Rab1aRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of RAB1A mRNACTDPMID:30047161
Rab1aRatall-trans-retinoic acid decreases expressionISORAB1A (Homo sapiens)6480464Tretinoin results in decreased expression of RAB1A mRNACTDPMID:15498508
Rab1aRatall-trans-retinoic acid increases expressionISORAB1A (Homo sapiens)6480464Tretinoin results in increased expression of RAB1A mRNACTDPMID:33167477
Rab1aRatamitrole increases expressionEXP 6480464Amitrole results in increased expression of RAB1A mRNACTDPMID:30047161
Rab1aRatammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of RAB1A mRNACTDPMID:16483693

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Biological Process
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Original Reference(s)
Rab1aRatautophagosome assembly involved_inISORAB1A (Homo sapiens)1624291 PMID:22939626RGDPMID:22939626
Rab1aRatautophagosome assembly involved_inIBAPANTHER:PTN000636233 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab1aRatautophagosome assembly involved_inISSUniProtKB:P628201600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRatautophagy involved_inISSUniProtKB:P628201600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRatautophagy involved_inIEAUniProtKB-KW:KW-00721600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatautophagy involved_inISORAB1A (Homo sapiens)1624291 PMID:22939626RGDPMID:22939626
Rab1aRatcell migration involved_inISORAB1A (Homo sapiens)1624291 PMID:20639577RGDPMID:20639577
Rab1aRatcell migration involved_inISORab1a (Mus musculus)1624291 PMID:20639577RGDPMID:20639577
Rab1aRatcell migration involved_inISSUniProtKB:P628201600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRatcilium assembly NOT|involved_inISORAB1A (Homo sapiens)1624291 PMID:17646400RGDPMID:17646400
Rab1aRatCOPII-coated vesicle cargo loading involved_inISORAB1A (Homo sapiens)1624291 PMID:17684057RGDPMID:17684057
Rab1aRatdefense response to bacterium involved_inISSUniProtKB:P628201600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRatdefense response to bacterium involved_inISORAB1A (Homo sapiens)1624291 PMID:22939626RGDPMID:22939626
Rab1aRatendocytosis involved_inIMP 8554665PMID:21303926UniProt 
Rab1aRatendocytosis involved_inISORAB1A (Homo sapiens)1624291 PMID:21303926RGDPMID:21303926
Rab1aRatendoplasmic reticulum to Golgi vesicle-mediated transport acts_upstream_of_or_withinIDA 8554056PMID:15728249MGI 
Rab1aRatendoplasmic reticulum to Golgi vesicle-mediated transport involved_inISORAB1A (Homo sapiens)1624291UniProtKB:Q9H0U4 more ...RGDPMID:17684057 more ...
Rab1aRatestablishment of endothelial intestinal barrier NOT|involved_inISORAB1A (Homo sapiens)1624291 PMID:23885123RGDPMID:23885123
Rab1aRatGolgi organization involved_inISSUniProtKB:P628201600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRatGolgi organization involved_inISORAB1A (Homo sapiens)1624291 PMID:17684057 and PMID:26209634RGDPMID:17684057 and PMID:26209634
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Cellular Component
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Original Reference(s)
Rab1aRatcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Rab1aRatcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Rab1aRatearly endosome located_inIDA 8554665PMID:21303926UniProt 
Rab1aRatearly endosome located_inIEAUniProtKB-SubCell:SL-00941600115GO_REF:0000044UniProtGO_REF:0000044
Rab1aRatendomembrane system is_active_inIBACGD:CAL0000194609 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab1aRatendoplasmic reticulum is_active_inISORAB1A (Homo sapiens)1624291 PMID:17684057RGDPMID:17684057
Rab1aRatendoplasmic reticulum located_inIEAUniProtKB-KW:KW-02561600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatendoplasmic reticulum located_inIEAUniProtKB-SubCell:SL-00951600115GO_REF:0000044UniProtGO_REF:0000044
Rab1aRatendoplasmic reticulum membrane  IDA 2306441 RGD 
Rab1aRatendosome located_inIEAUniProtKB-KW:KW-09671600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatexocytic vesicle located_inISORAB1A (Canis lupus familiaris)1624291 PMID:18504258RGDPMID:18504258
Rab1aRatGolgi apparatus located_inIEAUniProtKB-SubCell:SL-01321600115GO_REF:0000044UniProtGO_REF:0000044
Rab1aRatGolgi apparatus located_inIEAUniProtKB-KW:KW-03331600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatGolgi apparatus located_inISORab1a (Mus musculus)1624291 PMID:11042173RGDPMID:11042173
Rab1aRatGolgi membrane  IDA 2306441 RGD 
Rab1aRatmelanosome located_inISORab1a (Mus musculus)1624291 PMID:22854043RGDPMID:22854043
Rab1aRatmelanosome located_inIEAUniProtKB-SubCell:SL-01611600115GO_REF:0000044UniProtGO_REF:0000044
Rab1aRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
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Molecular Function
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Original Reference(s)
Rab1aRatG protein activity enablesIEAEC:3.6.5.21600115GO_REF:0000003UniProtGO_REF:0000003
Rab1aRatGTP binding  IDA 2306441 RGD 
Rab1aRatGTP binding enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
Rab1aRatGTP binding enablesIEAInterPro:IPR001806 and InterPro:IPR0052251600115GO_REF:0000002InterProGO_REF:0000002
Rab1aRatGTP binding enablesISSUniProtKB:Q9H0U41600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatGTPase activity enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
Rab1aRatGTPase activity enablesIBAFB:FBgn0015797 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rab1aRatGTPase activity enablesISORAB1A (Homo sapiens)1624291 PMID:17684057 and PMID:22939626RGDPMID:17684057 and PMID:22939626
Rab1aRatGTPase activity enablesISSUniProtKB:P628201600115GO_REF:0000024UniProtGO_REF:0000024
Rab1aRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Rab1aRatprotein binding enablesISORAB1A (Homo sapiens)1624291UniProtKB:P26374 more ...RGDPMID:15186776 more ...
Rab1aRatprotein binding enablesISORab1a (Mus musculus)1624291UniProtKB:Q6DFW0 and PMID:24549040RGDPMID:24549040
Rab1aRatprotein binding enablesISORAB1A (Canis lupus familiaris)1624291UniProtKB:P24386 and PMID:7957092RGDPMID:7957092
Rab1aRatprotein binding enablesISORAB1A (Homo sapiens) and UniProtKB:P62820-11624291UniProtKB:P50395 more ...RGDPMID:17952054 and PMID:20176951
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Reference Title
Reference Citation
1. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
2. Rho proteins are localized with different membrane compartments involved in vesicular trafficking in anterior pituitary cells. Cussac D, etal., Mol Cell Endocrinol. 1996 May 31;119(2):195-206.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons. Krijnse-Locker J, etal., Mol Biol Cell. 1995 Oct;6(10):1315-32.
5. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. Loh E, etal., J Cell Sci. 2005 Mar 15;118(Pt 6):1209-22. Epub 2005 Feb 22.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Proteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesicles. Mukhopadhyay A, etal., J Cell Sci. 2011 Mar 1;124(Pt 5):765-75. doi: 10.1242/jcs.079020. Epub 2011 Feb 8.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library. Touchot N, etal., Proc Natl Acad Sci U S A 1987 Dec;84(23):8210-4.
14. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
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PMID:11042173   PMID:15489334   PMID:15678101   PMID:15694364   PMID:15878873   PMID:16791210   PMID:16902405   PMID:17646400   PMID:17684057   PMID:18167358   PMID:18504258   PMID:20003598  
PMID:20417717   PMID:20458337   PMID:20639577   PMID:21095238   PMID:21680502   PMID:22082260   PMID:22854043   PMID:22939626   PMID:23885123   PMID:25468996   PMID:27502188   PMID:29476059  
PMID:31491505   PMID:31505169  



Rab1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,623,582 - 98,648,766 (+)NCBIGRCr8
mRatBN7.21494,422,219 - 94,448,799 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,415,275 - 94,448,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1498,769,042 - 98,794,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,009,313 - 100,034,363 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,476,690 - 96,501,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,475,082 - 104,500,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,475,082 - 104,501,020 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,208,420 - 104,235,377 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414100,973,039 - 101,027,893 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114100,992,249 - 101,047,101 (+)NCBI
Celera1493,445,267 - 93,470,406 (+)NCBICelera
Cytogenetic Map14q22NCBI
RAB1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38265,086,854 - 65,130,106 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl265,070,696 - 65,130,331 (-)EnsemblGRCh38hg38GRCh38
GRCh37265,313,988 - 65,357,240 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36265,167,493 - 65,210,793 (-)NCBINCBI36Build 36hg18NCBI36
Build 34265,225,639 - 65,268,940NCBI
Celera265,160,375 - 65,204,151 (-)NCBICelera
Cytogenetic Map2p14NCBI
HuRef265,047,966 - 65,091,371 (-)NCBIHuRef
CHM1_1265,244,946 - 65,288,425 (-)NCBICHM1_1
T2T-CHM13v2.0265,096,482 - 65,139,769 (-)NCBIT2T-CHM13v2.0
Rab1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,151,412 - 20,176,856 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,151,432 - 20,176,856 (+)EnsemblGRCm39 Ensembl
GRCm381120,201,412 - 20,226,856 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,201,432 - 20,226,856 (+)EnsemblGRCm38mm10GRCm38
MGSCv371120,101,605 - 20,126,859 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361120,101,605 - 20,126,859 (+)NCBIMGSCv36mm8
Celera1122,350,977 - 22,376,228 (+)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.92NCBI
Rab1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542419,393,589 - 19,421,373 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542419,393,589 - 19,421,373 (+)NCBIChiLan1.0ChiLan1.0
RAB1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21261,270,062 - 61,312,604 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A61,274,033 - 61,317,572 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A65,149,922 - 65,193,305 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A66,274,809 - 66,318,290 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A66,274,809 - 66,318,290 (-)Ensemblpanpan1.1panPan2
RAB1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11064,564,351 - 64,590,654 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1064,564,298 - 64,590,705 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1064,450,720 - 64,476,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01065,573,365 - 65,599,500 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1065,571,363 - 65,599,551 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11065,252,173 - 65,278,224 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01065,560,883 - 65,586,917 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01065,854,509 - 65,880,856 (-)NCBIUU_Cfam_GSD_1.0
Rab1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629218,679,767 - 18,712,642 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364919,858,645 - 9,891,674 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl376,837,430 - 76,869,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1376,837,673 - 76,868,156 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2380,675,435 - 80,712,268 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11441,890,055 - 41,932,180 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604569,948,865 - 69,995,044 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,420,305 - 8,449,647 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247628,420,336 - 8,448,478 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rab1a
210 total Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
14 104499404 104499405 C T snv PVG/Seac (2019) View more Information
14 104499419 104499420 A C snv PVG/Seac (2019) View more Information
14 104499545 104499546 G T snv FHL/EurMcwi (MCW) View more Information

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:21
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000021040
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)149255388695876975Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat

1 to 10 of 15 rows
RH139113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21494,439,357 - 94,439,493 (+)MAPPERmRatBN7.2
Rnor_6.014104,492,118 - 104,492,253NCBIRnor6.0
Rnor_5.014104,226,906 - 104,227,041UniSTSRnor5.0
RGSC_v3.414101,019,423 - 101,019,558UniSTSRGSC3.4
Celera1493,462,356 - 93,462,491UniSTS
RH 3.4 Map14746.49UniSTS
Cytogenetic Map14q22UniSTS
Rab1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81498,649,422 - 98,649,927 (+)Marker Load Pipeline
RGSC_v3.4131,669,138 - 31,669,640UniSTSRGSC3.4
Celera1493,467,746 - 93,467,962UniSTS
Cytogenetic Map14q22UniSTS
Rab1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21494,444,743 - 94,444,960 (+)MAPPERmRatBN7.2
Rnor_6.014104,497,516 - 104,497,732NCBIRnor6.0
Rnor_5.014104,232,717 - 104,232,933UniSTSRnor5.0
RGSC_v3.414101,025,233 - 101,025,449UniSTSRGSC3.4
Celera1493,467,746 - 93,467,962UniSTS
Cytogenetic Map14q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000021040   ⟹   ENSRNOP00000045598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,436,372 - 94,448,248 (+)Ensembl
Rnor_6.0 Ensembl14104,489,103 - 104,501,020 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078710   ⟹   ENSRNOP00000072088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,436,621 - 94,448,248 (+)Ensembl
Rnor_6.0 Ensembl14104,480,662 - 104,501,017 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084481   ⟹   ENSRNOP00000073493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,422,286 - 94,447,393 (+)Ensembl
Rnor_6.0 Ensembl14104,475,082 - 104,500,173 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098411   ⟹   ENSRNOP00000081304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,415,275 - 94,447,393 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103373   ⟹   ENSRNOP00000081611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,415,275 - 94,446,786 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103721   ⟹   ENSRNOP00000080734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,415,275 - 94,447,393 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107103   ⟹   ENSRNOP00000085984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,436,340 - 94,448,248 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112998   ⟹   ENSRNOP00000092933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,435,618 - 94,447,394 (+)Ensembl
RefSeq Acc Id: NM_031090   ⟹   NP_112352
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,623,677 - 98,648,766 (+)NCBI
mRatBN7.21494,422,311 - 94,447,404 (+)NCBI
Rnor_6.014104,475,082 - 104,500,176 (+)NCBI
Rnor_5.014104,208,420 - 104,235,377 (+)NCBI
RGSC_v3.414100,973,039 - 101,027,893 (+)RGD
Celera1493,445,267 - 93,470,406 (+)RGD
Sequence:
RefSeq Acc Id: XM_039092486   ⟹   XP_038948414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,623,582 - 98,648,766 (+)NCBI
mRatBN7.21494,422,219 - 94,448,799 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_112352 (Get FASTA)   NCBI Sequence Viewer  
  XP_038948414 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA42006 (Get FASTA)   NCBI Sequence Viewer  
  AAH66662 (Get FASTA)   NCBI Sequence Viewer  
  AAP86259 (Get FASTA)   NCBI Sequence Viewer  
  EDL97934 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073493
  ENSRNOP00000080734.1
  ENSRNOP00000107962
GenBank Protein Q6NYB7 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_112352   ⟸   NM_031090
- UniProtKB: P10536 (UniProtKB/Swiss-Prot),   Q6NYB7 (UniProtKB/Swiss-Prot),   A6JQ16 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045598   ⟸   ENSRNOT00000021040
Ensembl Acc Id: ENSRNOP00000073493   ⟸   ENSRNOT00000084481
Ensembl Acc Id: ENSRNOP00000072088   ⟸   ENSRNOT00000078710
RefSeq Acc Id: XP_038948414   ⟸   XM_039092486
- Peptide Label: isoform X1
- UniProtKB: A6JQ17 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-Q6NYB7-F1-model_v2 AlphaFold Q6NYB7 1-205 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699508
Promoter ID:EPDNEW_R10032
Type:initiation region
Name:Rab1a_1
Description:RAB1A, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014104,475,078 - 104,475,138EPDNEW


1 to 39 of 39 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14887 BioCyc
Ensembl Genes ENSRNOG00000004992 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000084481 ENTREZGENE
  ENSRNOT00000103721.1 UniProtKB/Swiss-Prot
  ENSRNOT00000167788 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5623442 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Rab UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
KEGG Report rno:81754 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72414 IMAGE-MGC_LOAD
NCBI Gene 81754 ENTREZGENE
PANTHER RAS-RELATED PROTEIN RAB UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot
PhenoGen Rab1a PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE RAB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004992 RatGTEx
SMART ARF UniProtKB/Swiss-Prot
  RAB UniProtKB/Swiss-Prot
  RAN UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2K235_RAT UniProtKB/TrEMBL
  A0A8I5ZU05_RAT UniProtKB/TrEMBL
  A0A8I5ZUS7_RAT UniProtKB/TrEMBL
  A0A8I6A1C8_RAT UniProtKB/TrEMBL
  A0A8I6AJ88_RAT UniProtKB/TrEMBL
  A0A8L2UQU9_RAT UniProtKB/TrEMBL
  A6JQ16 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ17 ENTREZGENE, UniProtKB/TrEMBL
  E9PU16_RAT UniProtKB/TrEMBL
  P10536 ENTREZGENE
  Q6NYB7 ENTREZGENE, UniProtKB/Swiss-Prot
  RAB1B_RAT UniProtKB/Swiss-Prot
UniProt Secondary P05711 UniProtKB/Swiss-Prot
1 to 39 of 39 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-29 Rab1a  RAB1A, member RAS oncogene family  Rab1  RAB1, member RAS oncogene family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Rab1  RAB1, member RAS oncogene family    ras-related protein  Name updated 1299863 APPROVED
2002-08-07 Rab1  ras-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL