Rab1a (RAB1A, member RAS oncogene family) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Rab1a (RAB1A, member RAS oncogene family) Rattus norvegicus
Analyze
Symbol: Rab1a
Name: RAB1A, member RAS oncogene family
RGD ID: 619736
Description: Enables GTP binding activity. Involved in endocytosis and vesicle transport along microtubule. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in several cellular components, including Golgi membrane; early endosome; and neuronal cell body. Is active in presynapse. Orthologous to human RAB1A (RAB1A, member RAS oncogene family); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ac2-048; Rab1; RAB1, member RAS oncogene family; Rab1r; ras-related protein; ras-related protein Rab-1A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rab1-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,623,582 - 98,648,766 (+)NCBIGRCr8
mRatBN7.21494,422,219 - 94,448,799 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,415,275 - 94,448,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1498,769,042 - 98,794,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,009,313 - 100,034,363 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,476,690 - 96,501,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,475,082 - 104,500,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,475,082 - 104,501,020 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,208,420 - 104,235,377 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414100,973,039 - 101,027,893 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114100,992,249 - 101,047,101 (+)NCBI
Celera1493,445,267 - 93,470,406 (+)NCBICelera
Cytogenetic Map14q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
clobetasol  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (EXP)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
diuron  (ISO)
ethanol  (ISO)
fenthion  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
graphite  (ISO)
hydralazine  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (ISO)
lovastatin  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
ozone  (EXP)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PhIP  (EXP)
piroxicam  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (EXP)
Tributyltin oxide  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
warfarin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
G protein activity  (IEA)
GTP binding  (IDA,IEA,ISS)
GTPase activity  (IBA,IEA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
2. Rho proteins are localized with different membrane compartments involved in vesicular trafficking in anterior pituitary cells. Cussac D, etal., Mol Cell Endocrinol. 1996 May 31;119(2):195-206.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons. Krijnse-Locker J, etal., Mol Biol Cell. 1995 Oct;6(10):1315-32.
5. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. Loh E, etal., J Cell Sci. 2005 Mar 15;118(Pt 6):1209-22. Epub 2005 Feb 22.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Proteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesicles. Mukhopadhyay A, etal., J Cell Sci. 2011 Mar 1;124(Pt 5):765-75. doi: 10.1242/jcs.079020. Epub 2011 Feb 8.
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Pavlos NJ, etal., J Neurosci. 2010 Oct 6;30(40):13441-53. doi: 10.1523/JNEUROSCI.0907-10.2010.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library. Touchot N, etal., Proc Natl Acad Sci U S A 1987 Dec;84(23):8210-4.
14. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Wilhelm BG, etal., Science. 2014 May 30;344(6187):1023-8. doi: 10.1126/science.1252884.
Additional References at PubMed
PMID:11042173   PMID:15489334   PMID:15678101   PMID:15694364   PMID:15878873   PMID:16791210   PMID:16902405   PMID:17646400   PMID:17684057   PMID:18167358   PMID:18504258   PMID:20003598  
PMID:20417717   PMID:20458337   PMID:20639577   PMID:21095238   PMID:21680502   PMID:22082260   PMID:22854043   PMID:22939626   PMID:23885123   PMID:25468996   PMID:27502188   PMID:29476059  
PMID:31491505   PMID:31505169  


Genomics

Comparative Map Data
Rab1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81498,623,582 - 98,648,766 (+)NCBIGRCr8
mRatBN7.21494,422,219 - 94,448,799 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1494,415,275 - 94,448,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1498,769,042 - 98,794,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.014100,009,313 - 100,034,363 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01496,476,690 - 96,501,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.014104,475,082 - 104,500,176 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl14104,475,082 - 104,501,020 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.014104,208,420 - 104,235,377 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.414100,973,039 - 101,027,893 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.114100,992,249 - 101,047,101 (+)NCBI
Celera1493,445,267 - 93,470,406 (+)NCBICelera
Cytogenetic Map14q22NCBI
RAB1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38265,086,854 - 65,130,106 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl265,070,696 - 65,130,331 (-)EnsemblGRCh38hg38GRCh38
GRCh37265,313,988 - 65,357,240 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36265,167,493 - 65,210,793 (-)NCBINCBI36Build 36hg18NCBI36
Build 34265,225,639 - 65,268,940NCBI
Celera265,160,375 - 65,204,151 (-)NCBICelera
Cytogenetic Map2p14NCBI
HuRef265,047,966 - 65,091,371 (-)NCBIHuRef
CHM1_1265,244,946 - 65,288,425 (-)NCBICHM1_1
T2T-CHM13v2.0265,096,482 - 65,139,769 (-)NCBIT2T-CHM13v2.0
Rab1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391120,151,412 - 20,176,856 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1120,151,432 - 20,176,856 (+)EnsemblGRCm39 Ensembl
GRCm381120,201,412 - 20,226,856 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1120,201,432 - 20,226,856 (+)EnsemblGRCm38mm10GRCm38
MGSCv371120,101,605 - 20,126,859 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361120,101,605 - 20,126,859 (+)NCBIMGSCv36mm8
Celera1122,350,977 - 22,376,228 (+)NCBICelera
Cytogenetic Map11A3.1NCBI
cM Map1112.92NCBI
Rab1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542419,393,589 - 19,421,373 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542419,393,589 - 19,421,373 (+)NCBIChiLan1.0ChiLan1.0
RAB1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21261,270,062 - 61,312,604 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A61,274,033 - 61,317,572 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A65,149,922 - 65,193,305 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A66,274,809 - 66,318,290 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A66,274,809 - 66,318,290 (-)Ensemblpanpan1.1panPan2
RAB1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11064,564,351 - 64,590,654 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1064,564,298 - 64,590,705 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1064,450,720 - 64,476,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01065,573,365 - 65,599,500 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1065,571,363 - 65,599,551 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11065,252,173 - 65,278,224 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01065,560,883 - 65,586,917 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01065,854,509 - 65,880,856 (-)NCBIUU_Cfam_GSD_1.0
Rab1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629218,679,767 - 18,712,642 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364919,858,645 - 9,891,674 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl376,837,430 - 76,869,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1376,837,673 - 76,868,156 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2380,675,435 - 80,712,268 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11441,890,055 - 41,932,180 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604569,948,865 - 69,995,044 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247628,420,305 - 8,449,647 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247628,420,336 - 8,448,478 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rab1a
210 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:21
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000021040
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582201Sffal2Serum free fatty acids level QTL 240.0002blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)149255388695876975Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1455624247100624247Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)147995092195876975Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1455147478100147478Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)144079346098037301Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1470053989104886043Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1458184885103184885Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147341532395876975Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1456631369101631369Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1470053989104886043Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)148205747195876975Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141103062295876975Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1455624247100624247Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144226252995023211Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)145002321195023211Rat

Markers in Region
RH139113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21494,439,357 - 94,439,493 (+)MAPPERmRatBN7.2
Rnor_6.014104,492,118 - 104,492,253NCBIRnor6.0
Rnor_5.014104,226,906 - 104,227,041UniSTSRnor5.0
RGSC_v3.414101,019,423 - 101,019,558UniSTSRGSC3.4
Celera1493,462,356 - 93,462,491UniSTS
RH 3.4 Map14746.49UniSTS
Cytogenetic Map14q22UniSTS
Rab1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4131,669,138 - 31,669,640UniSTSRGSC3.4
Celera1493,467,746 - 93,467,962UniSTS
Cytogenetic Map14q22UniSTS
Rab1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21494,444,743 - 94,444,960 (+)MAPPERmRatBN7.2
Rnor_6.014104,497,516 - 104,497,732NCBIRnor6.0
Rnor_5.014104,232,717 - 104,232,933UniSTSRnor5.0
RGSC_v3.414101,025,233 - 101,025,449UniSTSRGSC3.4
Celera1493,467,746 - 93,467,962UniSTS
Cytogenetic Map14q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000021040   ⟹   ENSRNOP00000045598
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,436,372 - 94,448,248 (+)Ensembl
Rnor_6.0 Ensembl14104,489,103 - 104,501,020 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078710   ⟹   ENSRNOP00000072088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,436,621 - 94,448,248 (+)Ensembl
Rnor_6.0 Ensembl14104,480,662 - 104,501,017 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084481   ⟹   ENSRNOP00000073493
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,422,286 - 94,447,393 (+)Ensembl
Rnor_6.0 Ensembl14104,475,082 - 104,500,173 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098411   ⟹   ENSRNOP00000081304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,415,275 - 94,447,393 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103373   ⟹   ENSRNOP00000081611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,415,275 - 94,446,786 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103721   ⟹   ENSRNOP00000080734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,415,275 - 94,447,393 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000107103   ⟹   ENSRNOP00000085984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,436,340 - 94,448,248 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112998   ⟹   ENSRNOP00000092933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1494,435,618 - 94,447,394 (+)Ensembl
RefSeq Acc Id: NM_031090   ⟹   NP_112352
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,623,677 - 98,648,766 (+)NCBI
mRatBN7.21494,422,311 - 94,447,404 (+)NCBI
Rnor_6.014104,475,082 - 104,500,176 (+)NCBI
Rnor_5.014104,208,420 - 104,235,377 (+)NCBI
RGSC_v3.414100,973,039 - 101,027,893 (+)RGD
Celera1493,445,267 - 93,470,406 (+)RGD
Sequence:
RefSeq Acc Id: XM_039092486   ⟹   XP_038948414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81498,623,582 - 98,648,766 (+)NCBI
mRatBN7.21494,422,219 - 94,448,799 (+)NCBI
RefSeq Acc Id: NP_112352   ⟸   NM_031090
- UniProtKB: P10536 (UniProtKB/Swiss-Prot),   Q6NYB7 (UniProtKB/Swiss-Prot),   A6JQ16 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045598   ⟸   ENSRNOT00000021040
Ensembl Acc Id: ENSRNOP00000073493   ⟸   ENSRNOT00000084481
Ensembl Acc Id: ENSRNOP00000072088   ⟸   ENSRNOT00000078710
RefSeq Acc Id: XP_038948414   ⟸   XM_039092486
- Peptide Label: isoform X1
- UniProtKB: A6JQ17 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092933   ⟸   ENSRNOT00000112998
Ensembl Acc Id: ENSRNOP00000081304   ⟸   ENSRNOT00000098411
Ensembl Acc Id: ENSRNOP00000080734   ⟸   ENSRNOT00000103721
Ensembl Acc Id: ENSRNOP00000081611   ⟸   ENSRNOT00000103373
Ensembl Acc Id: ENSRNOP00000085984   ⟸   ENSRNOT00000107103

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6NYB7-F1-model_v2 AlphaFold Q6NYB7 1-205 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699508
Promoter ID:EPDNEW_R10032
Type:initiation region
Name:Rab1a_1
Description:RAB1A, member RAS oncogene family
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.014104,475,078 - 104,475,138EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619736 AgrOrtholog
BioCyc Gene G2FUF-14887 BioCyc
Ensembl Genes ENSRNOG00000004992 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055007725 UniProtKB/Swiss-Prot
  ENSRNOG00060014698 UniProtKB/Swiss-Prot
  ENSRNOG00065006088 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000021040.8 UniProtKB/TrEMBL
  ENSRNOT00000078710.2 UniProtKB/TrEMBL
  ENSRNOT00000084481.2 UniProtKB/TrEMBL
  ENSRNOT00000098411.1 UniProtKB/TrEMBL
  ENSRNOT00000103373.1 UniProtKB/TrEMBL
  ENSRNOT00000103721.1 UniProtKB/Swiss-Prot
  ENSRNOT00000107103.1 UniProtKB/TrEMBL
  ENSRNOT00000112998.1 UniProtKB/TrEMBL
  ENSRNOT00055013072 UniProtKB/Swiss-Prot
  ENSRNOT00060025394 UniProtKB/Swiss-Prot
  ENSRNOT00065009329 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5623442 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rab UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_Rab UniProtKB/TrEMBL
KEGG Report rno:81754 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72414 IMAGE-MGC_LOAD
NCBI Gene 81754 ENTREZGENE
PANTHER LD21953P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LD44762P UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-1B UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rab1a PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004992 RatGTEx
  ENSRNOG00055007725 RatGTEx
  ENSRNOG00060014698 RatGTEx
  ENSRNOG00065006088 RatGTEx
SMART ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K235_RAT UniProtKB/TrEMBL
  A0A8I5ZU05_RAT UniProtKB/TrEMBL
  A0A8I5ZUS7_RAT UniProtKB/TrEMBL
  A0A8I6A1C8_RAT UniProtKB/TrEMBL
  A0A8I6AJ88_RAT UniProtKB/TrEMBL
  A0A8L2UQU9_RAT UniProtKB/TrEMBL
  A6JQ16 ENTREZGENE, UniProtKB/TrEMBL
  A6JQ17 ENTREZGENE, UniProtKB/TrEMBL
  E9PU16_RAT UniProtKB/TrEMBL
  P10536 ENTREZGENE
  Q6NYB7 ENTREZGENE, UniProtKB/Swiss-Prot
  RAB1B_RAT UniProtKB/Swiss-Prot
UniProt Secondary P05711 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-29 Rab1a  RAB1A, member RAS oncogene family  Rab1  RAB1, member RAS oncogene family  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Rab1  RAB1, member RAS oncogene family    ras-related protein  Name updated 1299863 APPROVED
2002-08-07 Rab1  ras-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL