Lrp4 Rat Gene (low density lipoprotein receptor-related protein 4)

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Keyword

Gene:
Lrp4 ( Rattus norvegicus )
low density lipoprotein receptor-related protein 4
Description: mouse homolog has similarity to the low density lipoprotein receptor family, however, it does not bind very low density lipoprotein
Synonyms: Megf7;
ArrayIDs: 6167817; 5939938; 6406294; 6426653; 6094461; 5683726; 6325618; 5965632; 1370932_at; 6415257; 6407906; 6371891; 6579441; 6223672; 6446123; rc_AI070976_at; 6548899; 5851977; 6340691; 6373741; A_43_P15727; 6553650; GE21251; 6448241; 6348580; 6247363; 6389226; 6270827; 6270232; A_43_P22637; 6307504; 6576969; 6334988; 6735012; 5938428; 5917942; 6278375; 6559403; 5721915; 6291009; 6312146; 6442275; 5720411; 6057267; 5979647; 6062595; 6482041; 6048556; 6047868; 5638682; 5658261; 6424539;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: LRP4     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Lrp4     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Lrp4 Rat Celera Assembly 3 76634746 - 76688537
RGSC genome assembly v3.4 3 75821638 - 75875100
Cytogenetic 3 q24
genome assembly 3.1 3 75718009 - 75771472
Mus musculus Lrp4 Mouse genome assembly build 36.1 2 91297858 - 91353936
Cytogenetic 2 2 E1
Homo sapiens LRP4 human genome assembly 11 46834994 - 46874397
Human genome assembly build 36.2 11 46834995 - 46896749
Cytogenetic 11 p11.2-p12

View comparative maps:      NCBI MapViewer

Genome
View:

Browsers:

Annotation
Molecular Function

Gene Ontology

receptor activity,  protein binding,  calcium ion binding (details...)
Biological Process

Gene Ontology

endocytosis,  embryonic limb morphogenesis,  dorsal/ventral pattern formation ... (details...)
Cellular Component

Gene Ontology

integral to membrane,  plasma membrane (details...)

External Links
Databases
DATABASE ID SOURCE
SMART: LY IPI
SMART: LDLa IPI
SMART: EGF_CA IPI
SMART: EGF IPI
PROSITE: LDLRB IPI
PROSITE: ASX_HYOXYL IPI
PROSITE: LDLRA_2 IPI
PROSITE: LDLRA_1 IPI
PROSITE: EGF_CA IPI
PROSITE: EGF_2 IPI
UNIPARC: UPI000035B210 IPI
UNIPARC: UPI0001B7B292 IPI
KEGG Report: rno:83469 ENTREZGENE
HomoloGene Group ID: 17964 ENTREZGENE
Germonline: 619731
Pfam: Ldl_recept_b IPI
Pfam: EGF IPI
Pfam: EGF_CA IPI
Pfam: Ldl_recept_a IPI
InterPro: EGF-type_Asp/Asn_hydroxyl_site. IPI
InterPro: LDL_rcpt_classA_cys-rich. IPI
InterPro: EGF_Ca_bd_CS. IPI
InterPro: EGF_Ca_bd_2. IPI
InterPro: EGF_Ca_bd. IPI
InterPro: LDLR. IPI
InterPro: EGF-like_reg_CS. IPI
InterPro: 6-blade_b-propeller_TolB-like. IPI
InterPro: EGF. IPI
InterPro: EGF-like. IPI
IPI: IPI00565170 IPI
IPI: IPI00373645 IPI
Ensembl Protein: ENSRNOP00000050218 IPI
Ensembl Protein: ENSRNOP00000021353 IPI
Gene3D-CATH: LDL_rcpt_classA_cys-rich IPI
Gene3D-CATH: 6-blade_b-propeller_TolB-like IPI
Entrez Gene: Lrp4 ENTREZGENE
UniProt: Q76LU2_RAT IPI
UniProt: LRP4_RAT IPI
Ensembl Genes: ENSRNOG00000015285 IPI
Superfamily-SCOP: LDL_rcpt_classA_cys-rich IPI
PRINTS: LDLRECEPTOR. IPI
Sequences
Nucleotide: NM_031322 Get FASTA Search GEO Profiles
Nucleotide: CH473949 Get FASTA Search GEO Profiles
Nucleotide: AB011533 Get FASTA Search GEO Profiles
Nucleotide: AB073317 Get FASTA Search GEO Profiles
(View all 4 Nucleotide Accessions)
Protein: BAA88688 Get FASTA
Protein: NP_112612 Get FASTA
Protein: EDL79527 Get FASTA
Protein: EDL79528 Get FASTA
Protein: BAD18061 Get FASTA
Protein: Q76LU2 Get FASTA
Protein: Q9QYP1 Get FASTA
(View all 7 Protein Accessions)
Clusters
UniGene: 21381

References
Curated References
5 references in RGD related to Lrp4

Other References
5 other references at PubMed related to Lrp4

Database Information
RGD ID 619731
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

10-SEP-04: Lrp4 low density lipoprotein receptor-related protein 4 APPROVED Symbol and Name status set to approved 1299863

07-AUG-02: Lrp4 low density lipoprotein receptor-related protein 4 PROVISIONAL Symbol and Name status set to provisional 70820