Rasd1 (ras related dexamethasone induced 1) - Rat Genome Database

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Gene: Rasd1 (ras related dexamethasone induced 1) Rattus norvegicus
Analyze
Symbol: Rasd1
Name: ras related dexamethasone induced 1
RGD ID: 619727
Description: Predicted to enable G-protein beta-subunit binding activity. Involved in negative regulation of DNA-templated transcription and nitric oxide mediated signal transduction. Located in nucleus and perinuclear region of cytoplasm. Orthologous to human RASD1 (ras related dexamethasone induced 1); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: dexamethasone-induced Ras-related protein 1; DEXRAS1 (Dexras1); MGC116281; RAS, dexamethasone-induced 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,265,975 - 45,275,279 (-)NCBIGRCr8
mRatBN7.21044,766,451 - 44,775,773 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1044,766,455 - 44,768,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1049,466,658 - 49,468,365 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01048,957,021 - 48,958,728 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01044,460,630 - 44,462,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,330,361 - 46,339,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,330,368 - 46,332,172 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,087,068 - 46,091,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,291,401 - 46,293,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,305,027 - 46,306,759 (-)NCBI
Celera1044,026,788 - 44,028,495 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane  (EXP)
1,2-dichloroethane  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetaldehyde  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-Zearalanol  (EXP)
amitriptyline  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
aripiprazole  (EXP)
aristolochic acid A  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bromobenzene  (EXP)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
choline  (ISO)
clofibric acid  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
dinophysistoxin 1  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
ethanol  (ISO)
fenarimol  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isoprenaline  (ISO)
kainic acid  (ISO)
kojic acid  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
melphalan  (ISO)
menadione  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methimazole  (EXP)
methylarsonic acid  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-Nitrosopyrrolidine  (ISO)
nevirapine  (ISO)
nitric oxide  (EXP)
nitroprusside  (EXP)
Nutlin-3  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
pentanal  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
Polygodial  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
S-nitrosoglutathione  (EXP)
SB 431542  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
Sunset Yellow FCF  (ISO)
T-2 toxin  (EXP)
tartrazine  (ISO)
tebuconazole  (EXP)
testosterone  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
undecane  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON. Fang M, etal., Neuron 2000 Oct;28(1):183-93.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription. Lau KF, etal., J Biol Chem. 2008 Dec 12;283(50):34728-37. doi: 10.1074/jbc.M801874200. Epub 2008 Oct 15.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17768032   PMID:18219571   PMID:19800018   PMID:20084551   PMID:21245950   PMID:22408026   PMID:24548484   PMID:26739966   PMID:26785766   PMID:28835591   PMID:36230939  


Genomics

Comparative Map Data
Rasd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81045,265,975 - 45,275,279 (-)NCBIGRCr8
mRatBN7.21044,766,451 - 44,775,773 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1044,766,455 - 44,768,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1049,466,658 - 49,468,365 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01048,957,021 - 48,958,728 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01044,460,630 - 44,462,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01046,330,361 - 46,339,326 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1046,330,368 - 46,332,172 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01046,087,068 - 46,091,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41046,291,401 - 46,293,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11046,305,027 - 46,306,759 (-)NCBI
Celera1044,026,788 - 44,028,495 (-)NCBICelera
Cytogenetic Map10q22NCBI
RASD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381717,494,437 - 17,496,395 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1717,494,437 - 17,496,395 (-)EnsemblGRCh38hg38GRCh38
GRCh371717,397,751 - 17,399,709 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361717,338,476 - 17,340,432 (-)NCBINCBI36Build 36hg18NCBI36
Build 341717,338,479 - 17,340,432NCBI
Celera1718,337,168 - 18,339,124 (-)NCBICelera
Cytogenetic Map17p11.2NCBI
HuRef1717,150,071 - 17,152,029 (-)NCBIHuRef
CHM1_11717,406,422 - 17,408,380 (-)NCBICHM1_1
T2T-CHM13v2.01717,441,046 - 17,443,004 (-)NCBIT2T-CHM13v2.0
Rasd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391159,854,007 - 59,855,770 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1159,854,007 - 59,855,770 (-)EnsemblGRCm39 Ensembl
GRCm381159,963,181 - 59,964,944 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1159,963,181 - 59,964,944 (-)EnsemblGRCm38mm10GRCm38
MGSCv371159,776,683 - 59,778,444 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361160,499,761 - 60,501,522 (-)NCBIMGSCv36mm8
MGSCv361159,779,376 - 59,781,137 (-)NCBIMGSCv36mm8
Cytogenetic Map11B1.3NCBI
cM Map1137.81NCBI
Rasd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955577452,993 - 454,713 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955577452,993 - 454,659 (+)NCBIChiLan1.0ChiLan1.0
RASD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21952,010,264 - 52,012,705 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11756,722,268 - 56,724,716 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01733,799,204 - 33,801,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11738,746,452 - 38,748,134 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1738,744,157 - 38,748,134 (+)Ensemblpanpan1.1panPan2
RASD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1541,965,091 - 41,966,812 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl541,965,164 - 41,966,817 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha542,103,168 - 42,104,890 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0542,071,293 - 42,073,036 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl542,071,367 - 42,072,357 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1542,038,332 - 42,040,052 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0541,985,700 - 41,987,441 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0542,177,627 - 42,179,348 (+)NCBIUU_Cfam_GSD_1.0
Rasd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560261,743,899 - 61,745,876 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367411,121,303 - 1,123,386 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367411,120,527 - 1,123,326 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,922,474 - 60,924,250 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,922,466 - 60,924,255 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,134,258 - 63,136,035 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RASD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11616,529,075 - 16,531,085 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1616,528,896 - 16,531,095 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660594,382,453 - 4,384,416 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rasd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248493,916,907 - 3,920,212 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248493,916,898 - 3,918,904 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rasd1
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:77
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000004475
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631552Vetf2Vascular elastic tissue fragility QTL 24.50.0002aorta elastic tissue integrity trait (VT:0010556)artery internal elastic lamina non-tumorous lesion count (CMO:0001913)104114263386142633Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1298078Stresp5Stress response QTL 52.990.00025blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1042045676104670812Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
61463Bp12Blood pressure QTL 126.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)104133325886333258Rat
8694173Bw149Body weight QTL 1494.380.001body mass (VT:0001259)body weight gain (CMO:0000420)104444169989441699Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
11528628Bss116Bone structure and strength QTL 1166.464e-07femur morphology trait (VT:0000559)femur length (CMO:0000442)104417977045632973Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
70188BpQTLcluster1Blood pressure QTL cluster 14.864arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)14232313287323132Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589030Epfw9Epididymal fat weight QTL 919.240.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)104444169989441699Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
70198BpQTLcluster9Blood pressure QTL cluster 92.94arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)104232313287323132Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
2317043Aia7Adjuvant induced arthritis QTL 73.82joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)103756507982565079Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
2317042Aia20Adjuvant induced arthritis QTL 203.38joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)103756507982565079Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103539226751793994Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
8552805Bw145Body weight QTL 1452.2body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)104194452678307017Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1576308Schws1Schwannoma susceptibility QTL 10.0041nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1040035094102359817Rat
631269Cia22Collagen induced arthritis QTL 228.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
631270Cia23Collagen induced arthritis QTL 233.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1040035094104060283Rat
7411614Foco18Food consumption QTL 180.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)104444169989441699Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
6893342Cm78Cardiac mass QTL 780.10.88heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)104287676679813922Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat

Markers in Region
RH128385  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21044,766,647 - 44,766,847 (+)MAPPERmRatBN7.2
Rnor_6.01046,330,558 - 46,330,757NCBIRnor6.0
Rnor_5.01046,087,265 - 46,087,464UniSTSRnor5.0
RGSC_v3.41046,291,598 - 46,291,797UniSTSRGSC3.4
Celera1044,026,985 - 44,027,184UniSTS
RH 3.4 Map10522.58UniSTS
Cytogenetic Map10q22UniSTS
RH132250  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21044,766,197 - 44,766,384 (+)MAPPERmRatBN7.2
Rnor_6.01046,330,108 - 46,330,294NCBIRnor6.0
Rnor_5.01046,086,815 - 46,087,001UniSTSRnor5.0
RGSC_v3.41046,291,148 - 46,291,334UniSTSRGSC3.4
Celera1044,026,535 - 44,026,721UniSTS
RH 3.4 Map10524.48UniSTS
Cytogenetic Map10q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000004475   ⟹   ENSRNOP00000004475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1044,766,455 - 44,768,186 (-)Ensembl
Rnor_6.0 Ensembl1046,330,368 - 46,332,172 (-)Ensembl
RefSeq Acc Id: NM_001270954   ⟹   NP_001257883
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,265,975 - 45,267,682 (-)NCBI
mRatBN7.21044,766,451 - 44,768,158 (-)NCBI
Rnor_6.01046,330,361 - 46,332,068 (-)NCBI
Rnor_5.01046,087,068 - 46,091,120 (-)NCBI
Celera1044,026,788 - 44,028,495 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008767871   ⟹   XP_008766093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,265,975 - 45,275,279 (-)NCBI
mRatBN7.21044,766,451 - 44,775,773 (-)NCBI
Rnor_6.01046,330,361 - 46,335,235 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086792   ⟹   XP_038942720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81045,265,975 - 45,275,279 (-)NCBI
mRatBN7.21044,766,451 - 44,775,773 (-)NCBI
RefSeq Acc Id: NP_001257883   ⟸   NM_001270954
- UniProtKB: Q4KLL2 (UniProtKB/Swiss-Prot),   Q9JKF8 (UniProtKB/Swiss-Prot),   A6HF22 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766093   ⟸   XM_008767871
- Peptide Label: isoform X1
- UniProtKB: Q4KLL2 (UniProtKB/Swiss-Prot),   Q9JKF8 (UniProtKB/Swiss-Prot),   A6HF22 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004475   ⟸   ENSRNOT00000004475
RefSeq Acc Id: XP_038942720   ⟸   XM_039086792
- Peptide Label: isoform X1
- UniProtKB: Q9JKF8 (UniProtKB/Swiss-Prot),   Q4KLL2 (UniProtKB/Swiss-Prot),   A6HF22 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JKF8-F1-model_v2 AlphaFold Q9JKF8 1-280 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697244
Promoter ID:EPDNEW_R7768
Type:single initiation site
Name:Rasd1_1
Description:ras related dexamethasone induced 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01046,332,113 - 46,332,173EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619727 AgrOrtholog
BioCyc Gene G2FUF-24868 BioCyc
Ensembl Genes ENSRNOG00000003348 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055026992 UniProtKB/Swiss-Prot
  ENSRNOG00060028492 UniProtKB/Swiss-Prot
  ENSRNOG00065007929 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000004475.7 UniProtKB/Swiss-Prot
  ENSRNOT00055046610 UniProtKB/Swiss-Prot
  ENSRNOT00060049527 UniProtKB/Swiss-Prot
  ENSRNOT00065012490 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7455971 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_RasD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64455 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:116281 IMAGE-MGC_LOAD
NCBI Gene 64455 ENTREZGENE
PANTHER DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIP08469P UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ras UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rasd1 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003348 RatGTEx
  ENSRNOG00055026992 RatGTEx
  ENSRNOG00060028492 RatGTEx
  ENSRNOG00065007929 RatGTEx
SMART RAB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6HF22 ENTREZGENE, UniProtKB/TrEMBL
  Q4KLL2 ENTREZGENE
  Q9JKF8 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q4KLL2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Rasd1  ras related dexamethasone induced 1  Rasd1  RAS, dexamethasone-induced 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Rasd1  RAS, dexamethasone-induced 1    DEXRAS1 (Dexras1)  Name updated 1299863 APPROVED
2002-08-07 Rasd1  DEXRAS1 (Dexras1)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression enriched in brain 633891
gene_product member of the Ras family of small monomeric G proteins 633891