Tdrd7 (tudor domain containing 7) - Rat Genome Database

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Pathways
Gene: Tdrd7 (tudor domain containing 7) Rattus norvegicus
Analyze
Symbol: Tdrd7
Name: tudor domain containing 7
RGD ID: 619724
Description: Predicted to enable mRNA binding activity. Predicted to be involved in several processes, including P granule organization; lens development in camera-type eye; and regulation of gene expression. Predicted to act upstream of or within germ cell development. Predicted to be located in chromatoid body. Predicted to be part of ribonucleoprotein complex. Predicted to be active in P granule. Human ortholog(s) of this gene implicated in cataract 36. Orthologous to human TDRD7 (tudor domain containing 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC93175; PCTAIRE2-binding protein; Pctaire2bp; trap; tudor domain-containing protein 7; tudor repeat associator with PCTAIRE 2; tudor repeat associator with PCTAIRE-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,034,317 - 65,108,165 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl565,034,341 - 65,108,161 (+)EnsemblGRCr8
mRatBN7.2560,238,742 - 60,312,548 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,238,678 - 60,312,544 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx562,218,203 - 62,285,075 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,037,710 - 64,104,582 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,006,961 - 64,073,831 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0561,557,909 - 61,631,719 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,564,864 - 61,631,710 (+)Ensemblrn6Rnor6.0
Rnor_5.0566,072,902 - 66,147,310 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4562,507,396 - 62,574,245 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera558,807,775 - 58,874,559 (+)NCBICelera
RGSC_v3.1562,507,574 - 62,574,420 (+)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (EXP,ISO)
alpha-phellandrene  (ISO)
amitrole  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
c-di-GMP  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
DDT  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
entinostat  (ISO)
fenthion  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
graphene oxide  (ISO)
hydrogen peroxide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
thimerosal  (ISO)
triadimefon  (EXP)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
mRNA binding  (IEA,ISO,ISS)
protein binding  (ISO)
RNA binding  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain. Hirose T, etal., Eur J Biochem 2000 Apr;267(7):2113-21.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17141210   PMID:21436445  


Genomics

Comparative Map Data
Tdrd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,034,317 - 65,108,165 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl565,034,341 - 65,108,161 (+)EnsemblGRCr8
mRatBN7.2560,238,742 - 60,312,548 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,238,678 - 60,312,544 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx562,218,203 - 62,285,075 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,037,710 - 64,104,582 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,006,961 - 64,073,831 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0561,557,909 - 61,631,719 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,564,864 - 61,631,710 (+)Ensemblrn6Rnor6.0
Rnor_5.0566,072,902 - 66,147,310 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4562,507,396 - 62,574,245 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera558,807,775 - 58,874,559 (+)NCBICelera
RGSC_v3.1562,507,574 - 62,574,420 (+)NCBI
Cytogenetic Map5q22NCBI
TDRD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38997,412,096 - 97,496,125 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl997,412,069 - 97,496,125 (+)Ensemblhg38GRCh38
GRCh379100,174,378 - 100,258,407 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36999,214,123 - 99,298,228 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34997,253,862 - 97,337,958NCBI
Celera970,688,547 - 70,772,637 (+)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef969,775,456 - 69,859,564 (+)NCBIHuRef
CHM1_19100,320,737 - 100,404,840 (+)NCBICHM1_1
T2T-CHM13v2.09109,584,046 - 109,668,073 (+)NCBIT2T-CHM13v2.0
Tdrd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39445,965,335 - 46,034,766 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl445,965,334 - 46,034,761 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38445,965,027 - 46,034,766 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl445,965,334 - 46,034,761 (+)Ensemblmm10GRCm38
MGSCv37445,985,295 - 46,047,633 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36445,993,523 - 46,055,861 (+)NCBIMGSCv36mm8
Celera445,993,958 - 46,056,906 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.48NCBI
Tdrd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541927,916,011 - 27,976,163 (-)Ensembl
ChiLan1.0NW_00495541927,919,664 - 27,983,426 (-)NCBIChiLan1.0ChiLan1.0
TDRD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21141,961,664 - 42,045,486 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1941,964,014 - 42,047,860 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0968,502,761 - 68,586,633 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1996,640,787 - 96,708,387 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl996,640,789 - 96,708,145 (+)EnsemblpanPan2panpan1.1
TDRD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11154,758,092 - 54,828,766 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1154,758,826 - 54,828,743 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1153,183,987 - 53,263,020 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01155,868,560 - 55,941,340 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1155,868,617 - 55,941,328 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11154,364,861 - 54,437,761 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01154,394,898 - 54,467,589 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,091,520 - 55,164,274 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tdrd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947169,721,060 - 169,775,479 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,249,016 - 6,322,815 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365246,268,640 - 6,323,059 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TDRD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,271,916 - 239,368,550 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11239,285,628 - 239,368,558 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21267,342,175 - 267,425,075 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TDRD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11241,903,454 - 41,984,534 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1241,903,448 - 41,984,442 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603838,956,973 - 39,042,188 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tdrd7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248253,303,041 - 3,386,606 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248253,302,796 - 3,376,971 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tdrd7
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11474,551 - 538,658 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tdrd7
376 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:382
Count of miRNA genes:143
Interacting mature miRNAs:164
Transcripts:ENSRNOT00000013650, ENSRNOT00000013726
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat

Markers in Region
D5Mit9  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8565,089,051 - 65,089,172 (+)Marker Load Pipeline
mRatBN7.2560,293,434 - 60,293,557 (+)MAPPERmRatBN7.2
Rnor_6.0561,612,600 - 61,612,720NCBIRnor6.0
Rnor_5.0566,128,197 - 66,128,317UniSTSRnor5.0
RGSC_v3.4562,555,131 - 62,555,252RGDRGSC3.4
RGSC_v3.4562,555,132 - 62,555,252UniSTSRGSC3.4
Celera558,855,517 - 58,855,636UniSTS
RGSC_v3.1562,555,311 - 62,555,431RGD
RH 3.4 Map5384.6RGD
RH 3.4 Map5384.6UniSTS
Cytogenetic Map5q22UniSTS
BE113498  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,266,192 - 60,266,346 (+)MAPPERmRatBN7.2
Rnor_6.0561,585,358 - 61,585,511NCBIRnor6.0
Rnor_5.0566,100,886 - 66,101,039UniSTSRnor5.0
RGSC_v3.4562,527,890 - 62,528,043UniSTSRGSC3.4
Celera558,828,269 - 58,828,422UniSTS
RH 3.4 Map5378.9UniSTS
Cytogenetic Map5q22UniSTS
RH143380  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,304,118 - 60,304,271 (+)MAPPERmRatBN7.2
Rnor_6.0561,623,284 - 61,623,436NCBIRnor6.0
Rnor_5.0566,138,881 - 66,139,033UniSTSRnor5.0
RGSC_v3.4562,565,816 - 62,565,968UniSTSRGSC3.4
Celera558,866,174 - 58,866,326UniSTS
RH 3.4 Map5380.8UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000085738   ⟹   ENSRNOP00000068568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl565,041,733 - 65,108,160 (+)Ensembl
mRatBN7.2 Ensembl560,245,699 - 60,312,544 (+)Ensembl
Rnor_6.0 Ensembl561,564,864 - 61,631,710 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089938   ⟹   ENSRNOP00000070634
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl565,041,984 - 65,108,160 (+)Ensembl
mRatBN7.2 Ensembl560,245,699 - 60,312,544 (+)Ensembl
Rnor_6.0 Ensembl561,565,439 - 61,631,673 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090186   ⟹   ENSRNOP00000070639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl565,034,341 - 65,108,161 (+)Ensembl
mRatBN7.2 Ensembl560,238,678 - 60,312,544 (+)Ensembl
Rnor_6.0 Ensembl561,565,064 - 61,631,710 (+)Ensembl
RefSeq Acc Id: NM_138871   ⟹   NP_620226
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,041,316 - 65,108,165 (+)NCBI
mRatBN7.2560,245,699 - 60,312,548 (+)NCBI
Rnor_6.0561,564,864 - 61,631,714 (+)NCBI
Rnor_5.0566,072,902 - 66,147,310 (+)NCBI
RGSC_v3.4562,507,396 - 62,574,245 (+)RGD
Celera558,807,775 - 58,874,559 (+)RGD
Sequence:
RefSeq Acc Id: XM_006238107   ⟹   XP_006238169
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,034,344 - 65,108,165 (+)NCBI
mRatBN7.2560,238,756 - 60,312,548 (+)NCBI
Rnor_6.0561,557,923 - 61,631,719 (+)NCBI
Rnor_5.0566,072,902 - 66,147,310 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006238108   ⟹   XP_006238170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,034,317 - 65,108,165 (+)NCBI
mRatBN7.2560,238,742 - 60,312,548 (+)NCBI
Rnor_6.0561,557,909 - 61,631,719 (+)NCBI
Rnor_5.0566,072,902 - 66,147,310 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763704   ⟹   XP_008761926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,041,077 - 65,108,165 (+)NCBI
mRatBN7.2560,245,460 - 60,312,548 (+)NCBI
Rnor_6.0561,564,625 - 61,631,714 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017593667   ⟹   XP_017449156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,041,890 - 65,108,165 (+)NCBI
mRatBN7.2560,246,260 - 60,312,548 (+)NCBI
Rnor_6.0561,565,342 - 61,631,719 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063288514   ⟹   XP_063144584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,074,001 - 65,108,165 (+)NCBI
RefSeq Acc Id: NP_620226   ⟸   NM_138871
- UniProtKB: Q5FVD0 (UniProtKB/Swiss-Prot),   Q9R1R4 (UniProtKB/Swiss-Prot),   A6IJA7 (UniProtKB/TrEMBL),   A0A8L2R2S9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238170   ⟸   XM_006238108
- Peptide Label: isoform X2
- UniProtKB: A0A8L2R3M8 (UniProtKB/TrEMBL),   A0A8L2R2S9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238169   ⟸   XM_006238107
- Peptide Label: isoform X1
- UniProtKB: A0A8L2R2S9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761926   ⟸   XM_008763704
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017449156   ⟸   XM_017593667
- Peptide Label: isoform X3
- UniProtKB: Q5FVD0 (UniProtKB/Swiss-Prot),   Q9R1R4 (UniProtKB/Swiss-Prot),   A6IJA7 (UniProtKB/TrEMBL),   A0A8L2R2S9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070639   ⟸   ENSRNOT00000090186
Ensembl Acc Id: ENSRNOP00000070634   ⟸   ENSRNOT00000089938
Ensembl Acc Id: ENSRNOP00000068568   ⟸   ENSRNOT00000085738
RefSeq Acc Id: XP_063144584   ⟸   XM_063288514
- Peptide Label: isoform X5
- UniProtKB: A6IJA8 (UniProtKB/TrEMBL)
Protein Domains
HTH OST-type   Tudor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9R1R4-F1-model_v2 AlphaFold Q9R1R4 1-1113 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693709
Promoter ID:EPDNEW_R4232
Type:initiation region
Name:Tdrd7_1
Description:tudor domain containing 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0561,565,003 - 61,565,063EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619724 AgrOrtholog
BioCyc Gene G2FUF-41422 BioCyc
Ensembl Genes ENSRNOG00000055779 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000085738 ENTREZGENE
  ENSRNOT00000085738.2 UniProtKB/Swiss-Prot
  ENSRNOT00000089938 ENTREZGENE
  ENSRNOT00000090186 ENTREZGENE
Gene3D-CATH 2.30.30.140 UniProtKB/Swiss-Prot
  2.40.50.90 UniProtKB/Swiss-Prot
  3.30.420.610 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7122915 IMAGE-MGC_LOAD
InterPro LOTUS-like UniProtKB/Swiss-Prot
  OST-HTH/LOTUS_dom UniProtKB/Swiss-Prot
  SNase_OB-fold_sf UniProtKB/Swiss-Prot
  TDRD7_LOTUS_3 UniProtKB/Swiss-Prot
  Tudor UniProtKB/Swiss-Prot
  Tudor_domain_containing UniProtKB/Swiss-Prot
  Tudor_TDRD7_rpt2 UniProtKB/Swiss-Prot
  Tudor_TDRD7_rpt3 UniProtKB/Swiss-Prot
KEGG Report rno:85425 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93175 IMAGE-MGC_LOAD
NCBI Gene 85425 ENTREZGENE
PANTHER TUDOR DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot
  TUDOR DOMAIN-CONTAINING PROTEIN 7 UniProtKB/Swiss-Prot
Pfam OST-HTH UniProtKB/Swiss-Prot
  TUDOR UniProtKB/Swiss-Prot
PhenoGen Tdrd7 PhenoGen
PROSITE HTH_OST UniProtKB/Swiss-Prot
  TUDOR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000055779 RatGTEx
SMART TUDOR UniProtKB/Swiss-Prot
Superfamily-SCOP Tudor/PWWP/MBT UniProtKB/Swiss-Prot
UniProt A0A8L2R2S9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R3M8 ENTREZGENE, UniProtKB/TrEMBL
  A6IJA7 ENTREZGENE, UniProtKB/TrEMBL
  A6IJA8 ENTREZGENE, UniProtKB/TrEMBL
  Q5FVD0 ENTREZGENE
  Q9R1R4 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q5FVD0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Tdrd7  tudor domain containing 7  Pctaire2bp  tudor repeat associator with PCTAIRE 2  Symbol and Name updated 1299863 APPROVED
2002-08-07 Pctaire2bp  tudor repeat associator with PCTAIRE 2      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes to the mitochondria 724644
gene_expression enriched in brain and testis 724644