Eci1 (enoyl-CoA delta isomerase 1) - Rat Genome Database

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Gene: Eci1 (enoyl-CoA delta isomerase 1) Rattus norvegicus
Analyze
Symbol: Eci1
Name: enoyl-CoA delta isomerase 1
RGD ID: 61892
Description: Enables delta(3)-delta(2)-enoyl-CoA isomerase activity and identical protein binding activity. Involved in fatty acid beta-oxidation. Located in mitochondrion. Orthologous to human ECI1 (enoyl-CoA delta isomerase 1); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 3,2 trans-enoyl-coenyme A isomerase; 3,2-trans-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase, mitochondrial; D3,D2-enoyl-CoA isomerase; Dci; delta(3),Delta(2)-enoyl-CoA isomerase; dodecenoyl-CoA isomerase; dodecenoyl-coenzyme A delta isomerase; dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase); dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase); dodecenoyl-Coenzyme A delta isomerase (32 trans-enoyl-Coenyme A isomerase); enoyl-CoA delta isomerase 1, mitochondrial; enoyl-Coenzyme A delta isomerase 1; MECI
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,961,250 - 13,974,595 (+)NCBIGRCr8
mRatBN7.21013,456,715 - 13,470,061 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,456,563 - 13,470,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,203,212 - 18,216,533 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,692,057 - 17,705,378 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,191,242 - 13,204,563 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,797,573 - 13,810,918 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,797,562 - 13,810,913 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,614,559 - 13,627,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,683,000 - 13,697,179 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,682,988 - 13,697,174 (+)NCBI
Celera1013,137,220 - 13,150,564 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
amiodarone  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
captan  (ISO)
chlordecone  (ISO)
chlorpyrifos  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
coumarin  (EXP)
cyclosporin A  (ISO)
cylindrospermopsin  (ISO)
decabromodiphenyl ether  (EXP)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
diquat  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (EXP)
ethanol  (ISO)
fenofibrate  (EXP,ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
gemfibrozil  (EXP)
gentamycin  (EXP)
indometacin  (EXP)
inulin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-ethionine  (EXP)
lamivudine  (ISO)
leflunomide  (EXP)
metformin  (EXP)
methapyrilene  (EXP)
methoxyacetic acid  (EXP)
methylmercury chloride  (EXP)
methylseleninic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (EXP)
Muraglitazar  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
ochratoxin A  (ISO)
omeprazole  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (EXP)
phenobarbital  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
raloxifene  (EXP)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiacloprid  (ISO)
thioacetamide  (EXP)
thiophanate-methyl  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
trovafloxacin  (ISO)
ursodeoxycholic acid  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
zidovudine  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
fatty acid beta-oxidation  (IBA,IDA,IEA,ISO,TAS)

Cellular Component
mitochondrial matrix  (IEA)
mitochondrion  (IBA,IDA,IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Domain swapping in the low-similarity isomerase/hydratase superfamily: the crystal structure of rat mitochondrial Delta3, Delta2-enoyl-CoA isomerase. Hubbard PA, etal., Protein Sci. 2005 Jun;14(6):1545-55. Epub 2005 May 9.
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Mitochondrial 3-2trans-Enoyl-CoA isomerase. Purification, cloning, expression, and mitochondrial import of the key enzyme of unsaturated fatty acid beta-oxidation. Muller-Newen G and Stoffel W, Biol Chem Hoppe Seyler 1991 Aug;372(8):613-24.
6. Amino acid sequence similarities of the mitochondrial short chain delta 3, delta 2-enoyl-CoA isomerase and peroxisomal multifunctional delta 3, delta 2-enoyl-CoA isomerase, 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase enzyme in rat liver. The proposed occurrence of isomerization and hydration in the same catalytic domain of the multifunctional enzyme. Palosaari PM, etal., J Biol Chem 1991 Jun 15;266(17):10750-3.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Functional characterization of Delta3,Delta2-enoyl-CoA isomerases from rat liver. Zhang D, etal., J Biol Chem. 2002 Mar 15;277(11):9127-32. Epub 2002 Jan 7.
Additional References at PubMed
PMID:1543742   PMID:11916962   PMID:12865426   PMID:14651853   PMID:16952422   PMID:18614015   PMID:20833797   PMID:23376485   PMID:30053369  


Genomics

Comparative Map Data
Eci1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,961,250 - 13,974,595 (+)NCBIGRCr8
mRatBN7.21013,456,715 - 13,470,061 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,456,563 - 13,470,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,203,212 - 18,216,533 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,692,057 - 17,705,378 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,191,242 - 13,204,563 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,797,573 - 13,810,918 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,797,562 - 13,810,913 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,614,559 - 13,627,904 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,683,000 - 13,697,179 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,682,988 - 13,697,174 (+)NCBI
Celera1013,137,220 - 13,150,564 (+)NCBICelera
Cytogenetic Map10q12NCBI
ECI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,239,402 - 2,251,587 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,239,402 - 2,252,300 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,289,403 - 2,301,588 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,229,897 - 2,241,604 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,229,898 - 2,241,576NCBI
Celera162,504,294 - 2,516,030 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,215,959 - 2,227,648 (-)NCBIHuRef
CHM1_1162,289,822 - 2,301,559 (-)NCBICHM1_1
T2T-CHM13v2.0162,261,850 - 2,274,034 (-)NCBIT2T-CHM13v2.0
Eci1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,645,657 - 24,658,290 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,645,615 - 24,658,322 (+)EnsemblGRCm39 Ensembl
GRCm381724,426,683 - 24,439,316 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,426,641 - 24,439,348 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,563,628 - 24,576,261 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,154,283 - 24,166,914 (+)NCBIMGSCv36mm8
Celera1724,939,193 - 24,953,366 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.39NCBI
Eci1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,010,412 - 15,027,014 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,010,412 - 15,027,014 (+)NCBIChiLan1.0ChiLan1.0
ECI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,741,784 - 2,753,362 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,522,684 - 6,534,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0161,097,165 - 1,108,726 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,339,864 - 2,351,221 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,339,864 - 2,351,385 (-)Ensemblpanpan1.1panPan2
ECI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,729,729 - 38,738,357 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,730,219 - 38,738,219 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,969,905 - 39,977,831 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,039,094 - 39,047,029 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,039,030 - 39,046,867 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,724,133 - 38,732,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,695,920 - 38,704,312 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,175,160 - 39,183,085 (+)NCBIUU_Cfam_GSD_1.0
Eci1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,902,157 - 104,914,806 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,794,670 - 1,807,299 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,794,673 - 1,807,306 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ECI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,750,742 - 39,758,516 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,750,742 - 39,758,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2342,422,314 - 42,425,576 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ECI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,135,042 - 2,147,246 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl52,135,129 - 2,147,109 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606828,910,452 - 28,924,540 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eci1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462482453,458 - 66,946 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462482453,174 - 66,986 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eci1
58 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:44
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000011784
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat

Markers in Region
RH138788  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,465,271 - 13,465,425 (+)MAPPERmRatBN7.2
Rnor_6.01013,806,129 - 13,806,282NCBIRnor6.0
Rnor_5.01013,623,115 - 13,623,268UniSTSRnor5.0
RGSC_v3.41013,692,390 - 13,692,543UniSTSRGSC3.4
Celera1013,145,775 - 13,145,928UniSTS
RH 3.4 Map10171.3UniSTS
Cytogenetic Map10q12UniSTS
RH141401  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21013,468,721 - 13,469,930 (+)MAPPERmRatBN7.2
Rnor_6.01013,809,579 - 13,810,787NCBIRnor6.0
Rnor_5.01013,626,565 - 13,627,773UniSTSRnor5.0
RGSC_v3.41013,695,840 - 13,697,048UniSTSRGSC3.4
Celera1013,149,225 - 13,150,433UniSTS
Cytogenetic Map10q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000011784   ⟹   ENSRNOP00000011784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,457,120 - 13,470,061 (+)Ensembl
Rnor_6.0 Ensembl1013,797,562 - 13,810,913 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083312   ⟹   ENSRNOP00000072341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,456,563 - 13,470,060 (+)Ensembl
Rnor_6.0 Ensembl1013,797,593 - 13,810,826 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119135   ⟹   ENSRNOP00000093771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1013,456,563 - 13,470,060 (+)Ensembl
RefSeq Acc Id: NM_017306   ⟹   NP_059002
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81013,961,250 - 13,974,595 (+)NCBI
mRatBN7.21013,456,715 - 13,470,061 (+)NCBI
Rnor_6.01013,797,573 - 13,810,918 (+)NCBI
Rnor_5.01013,614,559 - 13,627,904 (+)NCBI
RGSC_v3.41013,683,000 - 13,697,179 (+)RGD
Celera1013,137,220 - 13,150,564 (+)RGD
Sequence:
RefSeq Acc Id: NP_059002   ⟸   NM_017306
- Peptide Label: precursor
- UniProtKB: P23965 (UniProtKB/Swiss-Prot),   Q68G41 (UniProtKB/TrEMBL),   A0A8I6AJI3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000011784   ⟸   ENSRNOT00000011784
RefSeq Acc Id: ENSRNOP00000072341   ⟸   ENSRNOT00000083312
RefSeq Acc Id: ENSRNOP00000093771   ⟸   ENSRNOT00000119135

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P23965-F1-model_v2 AlphaFold P23965 1-289 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697010
Promoter ID:EPDNEW_R7534
Type:multiple initiation site
Name:Eci1_1
Description:enoyl-CoA delta isomerase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01013,797,558 - 13,797,618EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61892 AgrOrtholog
BioCyc Gene G2FUF-25860 BioCyc
BioCyc Pathway FAO-PWY [fatty acid beta-oxidation I (generic)] BioCyc
  PWY-5137 [fatty acid beta-oxidation III (unsaturated, odd number)] BioCyc
BioCyc Pathway Image FAO-PWY BioCyc
  PWY-5137 BioCyc
Ensembl Genes ENSRNOG00000008843 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055027196 UniProtKB/Swiss-Prot
  ENSRNOG00060010220 UniProtKB/Swiss-Prot
  ENSRNOG00065010437 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011784.5 UniProtKB/TrEMBL
  ENSRNOT00000083312.2 UniProtKB/TrEMBL
  ENSRNOT00000119135 ENTREZGENE
  ENSRNOT00000119135.1 UniProtKB/TrEMBL
  ENSRNOT00055047054 UniProtKB/Swiss-Prot
  ENSRNOT00060017270 UniProtKB/Swiss-Prot
  ENSRNOT00065016911 UniProtKB/Swiss-Prot
Gene3D-CATH 6.10.250.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7129389 IMAGE-MGC_LOAD
InterPro ClpP/crotonase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Enoyl-CoA_hyd/isom_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Enoyl-CoA_hydra/iso UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29740 UniProtKB/TrEMBL
MGC_CLONE MGC:93116 IMAGE-MGC_LOAD
NCBI Gene 29740 ENTREZGENE
PANTHER ENOYL-COA DELTA ISOMERASE 1, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENOYL-COA HYDRATASE-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ECH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Eci1 PhenoGen
PROSITE ENOYL_COA_HYDRATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008843 RatGTEx
  ENSRNOG00055027196 RatGTEx
  ENSRNOG00060010220 RatGTEx
  ENSRNOG00065010437 RatGTEx
Superfamily-SCOP SSF52096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K2R2_RAT UniProtKB/TrEMBL
  A0A8I6AJI3 ENTREZGENE, UniProtKB/TrEMBL
  ECI1_RAT UniProtKB/Swiss-Prot
  F7FE51_RAT UniProtKB/TrEMBL
  P23965 ENTREZGENE
  Q68G41 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-03 Eci1  enoyl-CoA delta isomerase 1  Eci1  enoyl-Coenzyme A delta isomerase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-03-17 Eci1  enoyl-Coenzyme A delta isomerase 1  Dci  dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Dci  dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)  Dci  dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-08 Dci  dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase)  Dci  dodecenoyl-coenzyme A delta isomerase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Dci  dodecenoyl-coenzyme A delta isomerase      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference