Advanced Search (OLGA)

Gene: Gabra6 (gamma-aminobutyric acid type A receptor subunit alpha6) Rattus norvegicus

Analyze

Symbol:

Gabra6

Name:

gamma-aminobutyric acid type A receptor subunit alpha6

RGD ID:

61861

Description:

Enables diazepam binding activity; heterocyclic compound binding activity; and inhibitory extracellular ligand-gated monoatomic ion channel activity. Contributes to GABA-A receptor activity; GABA-gated chloride ion channel activity; and benzodiazepine receptor activity. Involved in GABAergic synaptic transmission and response to ethanol. Located in dendrite; neuronal cell body membrane; and synaptic membrane. Part of receptor complex. Is active in several cellular components, including cerebellar Golgi cell to granule cell synapse; hippocampal mossy fiber to CA3 synapse; and postsynaptic specialization membrane. Used to study obesity. Orthologous to human GABRA6 (gamma-aminobutyric acid type A receptor subunit alpha6); INTERACTS WITH (S)-nicotine; ammonium chloride; Ampullosporin.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

GABA(A) receptor subunit alpha-6; GABA-A receptor alpha-6 subunit; GABAAR subunit alpha-6; gamma-aminobutyric acid (GABA) A receptor, alpha 6; gamma-aminobutyric acid (GABA-A) receptor subunit alpha 6; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6; gamma-aminobutyric acid A receptor, alpha 6; gamma-aminobutyric acid receptor subunit alpha-6; gamma-aminobutyric acid type A receptor alpha 6 subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Is Marker For:

Strains: ANT

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	27,311,965 - 27,327,337 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	27,311,979 - 27,327,234 (-)	Ensembl				GRCr8
mRatBN7.2	10	26,810,411 - 26,825,768 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	26,810,423 - 26,825,769 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	31,546,343 - 31,560,549 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	31,034,879 - 31,049,081 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	26,521,557 - 26,535,757 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	27,847,447 - 27,862,896 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	27,847,439 - 27,862,868 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	27,691,630 - 27,706,971 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	27,474,071 - 27,489,074 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	26,323,497 - 26,337,672 (-)	NCBI		Celera
RGSC_v3.1	10	27,475,119 - 27,490,123 (-)	NCBI
Cytogenetic Map	10	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Binge Drinking (IEP)

childhood absence epilepsy (ISO)

Cushing Syndrome (IAGP)

middle cerebral artery infarction (ISO)

obesity (IAGP)

schizophrenia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-palmitoylglycerol (ISO)

3alpha-hydroxy-5beta-pregnan-20-one (ISO)

acamprosate (ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

Ampullosporin (EXP)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bicuculline (EXP,ISO)

bisphenol A (EXP)

cadmium atom (ISO)

carbamazepine (ISO)

carbonyl sulfide (EXP)

carmustine (ISO)

colforsin daropate hydrochloride (EXP)

delta-hexachlorocyclohexane (ISO)

diazepam (EXP,ISO)

ethanol (EXP)

felbamate (ISO)

fipronil (ISO)

flumazenil (ISO)

folic acid (ISO)

gamma-aminobutyric acid (EXP,ISO)

gamma-hexachlorocyclohexane (ISO)

hydrogen sulfide (ISO)

ketamine (EXP)

maneb (ISO)

mercury atom (ISO)

mercury(0) (ISO)

methylmercury chloride (EXP)

midazolam (ISO)

naltrexone (ISO)

nicotine (EXP)

Niflumic acid (EXP)

paracetamol (ISO)

paraquat (ISO)

pentobarbital (EXP)

picrotoxinin (ISO)

pirinixic acid (ISO)

propofol (ISO)

sodium arsenate (ISO)

topiramate (EXP)

valproic acid (EXP,ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chloride transmembrane transport (IBA,IEA)

chloride transport (IEA)

gamma-aminobutyric acid signaling pathway (IBA,IEA,NAS)

inhibitory synapse assembly (IBA)

monoatomic ion transmembrane transport (IEA)

monoatomic ion transport (IEA)

regulation of postsynaptic membrane potential (IEA)

response to ethanol (IEP)

synaptic transmission, GABAergic (IBA,IMP)

Cellular Component

cerebellar Golgi cell to granule cell synapse (IDA,IEA,ISO)

chloride channel complex (IEA)

dendrite (IDA)

dendrite membrane (IBA)

GABA-A receptor complex (IBA)

GABA-ergic synapse (IDA,IEA)

hippocampal mossy fiber to CA3 synapse (IDA)

membrane (IEA)

neuronal cell body membrane (IDA)

plasma membrane (IDA,IEA)

postsynapse (IBA)

postsynaptic membrane (IDA,IEA)

postsynaptic specialization membrane (IDA,IEA)

presynaptic membrane (IDA)

receptor complex (IDA)

Molecular Function

benzodiazepine receptor activity (IBA,IMP)

chloride channel activity (IBA,IEA)

diazepam binding (IDA)

extracellular ligand-gated monoatomic ion channel activity (IEA)

GABA-A receptor activity (IBA,IDA,IEA)

GABA-gated chloride ion channel activity (IMP)

heterocyclic compound binding (IDA)

inhibitory extracellular ligand-gated monoatomic ion channel activity (IMP)

monoatomic ion channel activity (IEA)

protein-containing complex binding (IPI)

transmembrane signaling receptor activity (IEA)

transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (IEA,ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

alcohol preference (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	AA and ANA rats exhibit the R100Q mutation in the GABAA receptor alpha 6 subunit.	Carr LG, etal., Alcohol. 2003 Aug-Oct;31(1-2):93-7.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GABAA receptors: structure, function, pharmacology, and related disorders.	Ghit A, etal., J Genet Eng Biotechnol. 2021 Aug 21;19(1):123. doi: 10.1186/s43141-021-00224-0.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Rat alpha6beta2delta GABAA receptors exhibit two distinct and separable agonist affinities.	Hadley SH and Amin J, J Physiol. 2007 Jun 15;581(Pt 3):1001-18. Epub 2007 Mar 29.
6.	Cerebellar GABAA receptor selective for a behavioural alcohol antagonist.	Luddens H, etal., Nature 1990 Aug 16;346(6285):648-51.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	The alpha 6 subunit of the GABAA receptor is concentrated in both inhibitory and excitatory synapses on cerebellar granule cells.	Nusser Z, etal., J Neurosci. 1996 Jan;16(1):103-14.
10.	Segregation of different GABAA receptors to synaptic and extrasynaptic membranes of cerebellar granule cells.	Nusser Z, etal., J Neurosci. 1998 Mar 1;18(5):1693-703.
11.	Subunit composition and quantitative importance of GABA(A) receptor subtypes in the cerebellum of mouse and rat.	Poltl A, etal., J Neurochem. 2003 Dec;87(6):1444-55.
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	Allelic variants in the GABA(A)alpha6 receptor subunit gene (GABRA6) is associated with abdominal obesity and cortisol secretion.	Rosmond R, etal., Int J Obes Relat Metab Disord. 2002 Jul;26(7):938-41.
16.	Contributions of the GABAA receptor alpha6 subunit to phasic and tonic inhibition revealed by a naturally occurring polymorphism in the alpha6 gene.	Santhakumar V, etal., J Neurosci. 2006 Mar 22;26(12):3357-64.
17.	Ethanol concentration-dependent alterations in gene expression during acute binge drinking in the HIV-1 transgenic rat.	Sarkar S and Chang SL, Alcohol Clin Exp Res. 2013 Jul;37(7):1082-90. doi: 10.1111/acer.12077. Epub 2013 Feb 15.
18.	Presynaptic GABAA receptors facilitate GABAergic transmission to dopaminergic neurons in the ventral tegmental area of young rats.	Xiao C, etal., J Physiol. 2007 May 1;580(Pt.3):731-43. Epub 2007 Feb 15.

Additional References at PubMed

PMID:1312131	PMID:1312132	PMID:1346133	PMID:1379501	PMID:1665550	PMID:1966765	PMID:15579538	PMID:15950783	PMID:18056985	PMID:22521829	PMID:23602886	PMID:25128322
PMID:26134650	PMID:27388150	PMID:34332026

Genomics

Comparative Map Data

Gabra6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	27,311,965 - 27,327,337 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	27,311,979 - 27,327,234 (-)	Ensembl				GRCr8
mRatBN7.2	10	26,810,411 - 26,825,768 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	26,810,423 - 26,825,769 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	31,546,343 - 31,560,549 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	31,034,879 - 31,049,081 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	26,521,557 - 26,535,757 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	27,847,447 - 27,862,896 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	27,847,439 - 27,862,868 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	27,691,630 - 27,706,971 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	27,474,071 - 27,489,074 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	26,323,497 - 26,337,672 (-)	NCBI		Celera
RGSC_v3.1	10	27,475,119 - 27,490,123 (-)	NCBI
Cytogenetic Map	10	q21	NCBI

GABRA6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	161,685,721 - 161,702,592 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	161,547,063 - 161,702,593 (+)	Ensembl			hg38	GRCh38
GRCh37	5	161,112,727 - 161,129,598 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	161,045,236 - 161,062,176 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	5	161,045,547 - 161,061,697	NCBI
Celera	5	157,144,516 - 157,161,456 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI
HuRef	5	156,205,057 - 156,221,975 (+)	NCBI		HuRef
CHM1_1	5	160,545,077 - 160,562,018 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	162,214,591 - 162,231,464 (+)	NCBI		T2T-CHM13v2.0

Gabra6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	42,197,264 - 42,211,977 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	42,197,264 - 42,211,899 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	42,306,437 - 42,321,072 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	42,306,437 - 42,321,072 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	42,119,939 - 42,134,553 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	42,149,861 - 42,164,431 (-)	NCBI		MGSCv36	mm8
Celera	11	46,139,046 - 46,153,582 (-)	NCBI		Celera
Cytogenetic Map	11	A5	NCBI
cM Map	11	25.03	NCBI

Gabra6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	15,464,368 - 15,480,330 (+)	Ensembl
ChiLan1.0	NW_004955408	15,464,426 - 15,479,653 (+)	NCBI	ChiLan1.0	ChiLan1.0

GABRA6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	156,868,647 - 156,885,816 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	155,008,214 - 155,025,362 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	157,072,915 - 157,089,994 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	163,767,304 - 163,784,334 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	163,767,304 - 163,784,331 (+)	Ensembl			panPan2	panpan1.1

GABRA6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	49,208,691 - 49,225,754 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	49,208,605 - 49,226,212 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	49,099,501 - 49,116,828 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	49,639,863 - 49,657,617 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	49,640,367 - 49,657,815 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	49,446,978 - 49,464,698 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	49,579,983 - 49,597,659 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	50,103,326 - 50,121,062 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gabra6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	103,533,076 - 103,548,851 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936515	1,980,824 - 1,998,053 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936515	1,982,415 - 1,997,740 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GABRA6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	61,855,468 - 61,872,279 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	16	61,855,698 - 61,872,503 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	67,083,554 - 67,100,297 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GABRA6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	64,020,770 - 64,038,419 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	64,021,842 - 64,039,563 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666034	13,515,669 - 13,532,119 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gabra6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	27,910,641 - 27,926,376 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624733	27,910,692 - 27,926,104 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gabra6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	25,172,933 - 25,187,711 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gabra6
182 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	98
Count of miRNA genes:	74
Interacting mature miRNAs:	90
Transcripts:	ENSRNOT00000004877
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15776754	60776754	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2313066	Bss63	Bone structure and strength QTL 63	1.4	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	10	5893811	50893811	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1250554	64349221	Rat
2313064	Bmd71	Bone mineral density QTL 71	0.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	10	5893811	50893811	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	14653541	59653541	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
1578761	Stresp21	Stress response QTL 21	3.3		thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	6877142	51877142	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	27023535	61843633	Rat
2293680	Bss40	Bone structure and strength QTL 40	5.66	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	10	1	35730538	Rat
7387235	Uae41	Urinary albumin excretion QTL 41	5.26	0.1874	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	10	1	30004247	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	19939207	64939207	Rat
61332	Eau3	Experimental allergic uveoretinitis QTL 3		0.004	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	18035782	63035782	Rat
10401803	Kidm50	Kidney mass QTL 50			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	10	922197	45922197	Rat
2317754	Glom25	Glomerulus QTL 25	3.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	2103708	47103708	Rat
2313081	Bss64	Bone structure and strength QTL 64	1.3	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	10	5893811	50893811	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	16175525	61175525	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18668419	63668419	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	20110614	65110614	Rat
634327	Hc4	Hypercalciuria QTL 4	2.4		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	10	1	38832698	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21833758	61843633	Rat
631531	Iresp2	Immunoglobin response QTL2	6.3		blood immunoglobulin E amount (VT:0002492)	serum immunoglobulin E level (CMO:0002101)	10	23422121	32490778	Rat
2313095	Bss62	Bone structure and strength QTL 62	1.5	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
631660	Hcar1	Hepatocarcinoma resistance QTL 1	3.4	0.0001	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	10	6661118	35509383	Rat
631532	Cm50	Cardiac mass QTL 50	6.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	18035782	63035782	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
2313104	Bss61	Bone structure and strength QTL 61	0.9	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	10	5893811	50893811	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	20110614	65110614	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Markers in Region

RH138854

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	10	27,314,509 - 27,314,628 (+)	Marker Load Pipeline
mRatBN7.2	10	26,812,955 - 26,813,074 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	27,849,992 - 27,850,110	NCBI	Rnor6.0
Rnor_5.0	10	27,694,175 - 27,694,293	UniSTS	Rnor5.0
RGSC_v3.4	10	27,475,805 - 27,475,923	UniSTS	RGSC3.4
Celera	10	26,325,231 - 26,325,349	UniSTS
RH 3.4 Map	10	279.9	UniSTS
Cytogenetic Map	10	q21	UniSTS

X51986

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	26,810,832 - 26,810,942 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	27,847,869 - 27,847,978	NCBI	Rnor6.0
Rnor_5.0	10	27,692,052 - 27,692,161	UniSTS	Rnor5.0
RGSC_v3.4	10	27,473,682 - 27,473,791	UniSTS	RGSC3.4
Celera	10	26,323,108 - 26,323,217	UniSTS
Cytogenetic Map	10	q21	UniSTS

Related Rat Strains

The following Strains have been annotated to Gabra6

ANT

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	8	60	16	17	7	9	7	38	22	55	2	22	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L08495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X55742	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004877 ⟹ ENSRNOP00000004877

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	27,311,979 - 27,327,234 (-)	Ensembl
mRatBN7.2 Ensembl	10	26,810,423 - 26,825,769 (-)	Ensembl
Rnor_6.0 Ensembl	10	27,847,439 - 27,862,868 (-)	Ensembl

RefSeq Acc Id:

NM_021841 ⟹ NP_068613

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	27,311,965 - 27,327,234 (-)	NCBI
mRatBN7.2	10	26,810,411 - 26,825,680 (-)	NCBI
Rnor_6.0	10	27,848,258 - 27,862,506 (-)	NCBI
Rnor_5.0	10	27,691,630 - 27,706,971 (-)	NCBI
RGSC_v3.4	10	27,474,071 - 27,489,074 (-)	RGD
Celera	10	26,323,497 - 26,337,672 (-)	RGD

Sequence:

show sequence

ATGCTGTTGCTTCTCCCCTGGCTCTTCAGTTTACTATGGATAGAAAATGCCCAAGCTCAACTTG
AAGATGAAGGGAACTTCTATTCTGAAAATGTCAGTCGGATTCTTGACAACTTGCTGGAGGGCTA
TGACAACCGTCTACGGCCGGGATTTGGAGGTGCTGTAACAGAGGTCAAAACAGATATCTATGTG
ACCAGCTTTGGGCCTGTGTCAGATGTGGAGATGGAGTACACAATGGATGTTTTCTTCCGACAGA
CATGGACTGATGAGAGGCTGAAGTTCAAAGGCCCTGCTGAGATTTTGAGTTTAAATAACTTGAT
GGTCAGTAAGATCTGGACTCCGGACACATTTTTCCGAAATGGGAAAAAGTCAATTGCTCACAAC
ATGACCACCCCTAACAAACTCTTCCGATTGATGCATAATGGAACGATCCTGTACACCATGAGGC
TTACCATCAACGCTGACTGTCCGATGAGACTGGTTAACTTCCCTATGGATGGACACGCATGTCC
ACTCAAGTTTGGGAGCTATGCCTATCCGAAAAGCGAAATCATATATACATGGAAAAAAGGACCG
CTTTATTCAGTAGAGGTCCCAGAAGAATCTTCAAGCCTCCTCCAGTATGATTTGATTGGGCAAA
CAGTTTCTAGTGAGACTATTAAATCGAACACAGGTGAATATGTAATAATGACAGTCTACTTCCA
CTTACAAAGGAAGATGGGCTATTTCATGATCCAGATTTACACTCCGTGCATCATGACAGTCATT
CTCTCTCAAGTGTCTTTCTGGATTAATAAGGAGTCGGTCCCAGCAAGAACCGTCTTTGGAATCA
CCACGGTTTTAACCATGACCACCTTAAGCATCAGTGCTCGGCACTCTCTACCCAAAGTGTCCTA
TGCAACCGCCATGGATTGGTTCATAGCTGTATGCTTTGCGTTTGTCTTTTCTGCTCTCATTGAA
TTCGCAGCTGTCAACTACTTCACCAATCTCCAGTCCCAGAAAGCCGAAAGGCAGGCACAGACTG
CAGCCAAGCCCCCGGTAGCAAAGTCAAAAACAACTGAATCACTGGAAGCTGAGATTGTTGTGCA
CTCTGACTCCAAGTACCATCTGAAGAAGAGAATCAGCTCTCTGACTTTGCCAATCGTTCCATCT
TCTGAGGCCAGCAAAGTCCTCAGTAGAACGCCCATCTTACCATCAACGCCGGTCACTCCCCCAT
TGCTCTTACCAGCCATTGGCGGCACCAGCAAAATAGATCAATATTCTCGAATTCTCTTCCCAGT
AGCATTTGCAGGATTCAACCTTGTGTACTGGATAGTTTACCTTTCCAAAGATACAATGGAAGTG
AGCAGTACTGTCGAGTAG

hide sequence

RefSeq Acc Id:

XM_006246128 ⟹ XP_006246190

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	27,311,965 - 27,327,337 (-)	NCBI
mRatBN7.2	10	26,810,411 - 26,825,768 (-)	NCBI
Rnor_6.0	10	27,847,447 - 27,862,896 (-)	NCBI
Rnor_5.0	10	27,691,630 - 27,706,971 (-)	NCBI

Sequence:

show sequence

GATTTCCTCACAGGTCCTTCTAATTCCATGCCAAAACTAGCTGTGGATTTCTTCCTTTTAATCT
CCCCTGATGCCTTAGTCAATTATTGTCATTTCTCTGACTCTCCACTTTCCAACTGAACCAGTCA
GAGGAGGCTGGGTATCTGCAGGACTTAATCTAAGACCACAAACGACCCTATTCCATGAGAAAAG
ACAGAAATAAGACAAAAAAGAAGGGAACCCTTAACATTTTATTGGCAAACCATTCATCTATTGG
ATTCCTGACTGGTCACAGATTGAGATAAGGAATATGAAGGATTTGGAAGATTTCTCCAGTTGAT
TGTCAAAGGAGATCTGGCTGAGGGGAGGAAGAAAGCAGGAGGGTGACCTGGCATTTCAGTGAAC
TATAGGATGCTGTTGCTTCTCCCCTGGCTCTTCAGTTTACTATGGATAGAAAATGCCCAAGCTC
AACTTGAAGATGAAGGGAACTTCTATTCTGAAAATGTCAGTCGGATTCTTGACAACTTGCTGGA
GGGCTATGACAACCGTCTACGGCCGGGATTTGGAGGTGCTGTAACAGAGGTCAAAACAGATATC
TATGTGACCAGCTTTGGGCCTGTGTCAGATGTGGAGATGACATGGACTGATGAGAGGCTGAAGT
TCAAAGGCCCTGCTGAGATTTTGAGTTTAAATAACTTGATGGTCAGTAAGATCTGGACTCCGGA
CACATTTTTCCAAAATGGGAAAAAGTCAATTGCTCACAACATGACCACCCCTAACAAACTCTTC
CGATTGATGCAGAATGGAACGATCCTGTACACCATGAGGCTTACCATCAACGCTGACTGTCCGA
TGAGACTGGTTAACTTCCCTATGGATGGACACGCATGTCCACTCAAGTTTGGGAGCTATGCCTA
TCCGAAAAGCGAAATCATATATACATGGAAAAAAGGACCGCTTTATTCAGTAGAGGTCCCAGAA
GAATCTTCAAGCCTCCTCCAGTATGATTTGATTGGGCAAACAGTTTCTAGTGAGACTATTAAAT
CGAACACAGGTGAATATGTAATAATGACAGTCTACTTCCACTTACAAAGGAAGATGGGCTATTT
CATGATCCAGATTTACACTCCGTGCATCATGACAGTCATTCTCTCTCAAGTGTCTTTCTGGATT
AATAAGGAGTCGGTCCCAGCAAGAACCGTCTTTGGAATCACCACGGTTTTAACCATGACCACCT
TAAGCATCAGTGCTCGGCACTCTCTACCCAAAGTGTCCTATGCAACCGCCATGGATTGGTTCAT
AGCTGTATGCTTTGCGTTTGTCTTTTCTGCTCTCATTGAATTCGCAGCTGTCAACTACTTCACC
AATCTCCAGTCCCAGAAAGCCGAAAGGCAGGCACAGACTGCAGCCAAGCCCCCGGTAGCAAAGT
CAAAAACAACTGAATCACTGGAAGCTGAGATTGTTGTGCACTCTGACTCCAAGTACCATCTGAA
GAAGAGAATCAGCTCTCTGACTTTGCCAATCGTTCCATCTTCTGAGGCCAGCAAAGTCCTCAGT
AGAACGCCCATCTTACCATCAACGCCGGTCACTCCCCCATTGCTCTTACCAGCCATTGGCGGCA
CCAGCAAAATAGATCAATATTCTCGAATTCTCTTCCCAGTAGCATTTGCAGGATTCAACCTTGT
GTACTGGATAGTTTACCTTTCCAAAGATACAATGGAAGTGAGCAGTACTGTCGAGTAGTTTGCA
GCCAGGAAAAGCTGGACACTGTAATTGGTTATTTTCCATTTTCCTCGCTTACAGAACACAAATT
ATTGTGTTAGTATAAATGGTCTCATTTCAGAAACTAAATGTCTATATTTCATAATATGGAATAA
GCATGTTTGGGCTAAAAACAATAATATTACTCTTCAAAATTAAATTTAGAAAGCTACTGAAAAT
ATGAATTTTCTGTATAGTAAAATTAATAATAATAATAATAACAATAATATCAGCATTTATGTGG
ATAAGGTAGATTCAAAATGAGTTTGCCAACCTTTGTCTTCATTGTTCAATATTTTTAATTGTCA
CTGTGAATAACATTTTCCACAAAGCAGATATATTCAGATATGCTGACCCTTCTAAAGCTTGCCT
TAAATTTGTTTATTTTGGCTTAGTTTCTACTCTAAACATTTATTGGTATGTTTATACAGCATGC
TGGAGGCCTTTGCGATTTTACAAGAACTCTCACTGGCATTGAACTGCTTATATTGAGATTAGAC
ATTTCTTTTTAACCTTGCTGTGTTCTTTTACCTCAATAAAATGTGGCATTATATACACATAAAT
AATACATAGTTTATAAATTATGTATGCATATGTACATAGCTTTAGTTATGCTGCAATACTGTTG
CTATTTCCCACTAAATTCACCTTTAAGAAGATGATGCTTGACATAACACCAGGAGGTTCTAGGA
AGGTCACTCAATGTACTATGACTGTATATTCTGATTCGGATTACCATTGTGTGTTACACTTTCC
TAAATATAATGCCAAATAAAACCACAAAAAGCCTGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_068613	(Get FASTA)	NCBI Sequence Viewer
	XP_006246190	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC42034	(Get FASTA)	NCBI Sequence Viewer
	CAA39273	(Get FASTA)	NCBI Sequence Viewer
	EDM04122	(Get FASTA)	NCBI Sequence Viewer
	EDM04123	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004877
GenBank Protein	P30191	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_068613 ⟸ NM_021841
- Peptide Label:	precursor
- UniProtKB:	P30191 (UniProtKB/Swiss-Prot), G3V6G3 (UniProtKB/TrEMBL), A6HDL8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLLPWLFSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYV TSFGPVSDVEMEYTMDVFFRQTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFRNGKKSIAHN MTTPNKLFRLMHNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGP LYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVI LSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIE FAAVNYFTNLQSQKAERQAQTAAKPPVAKSKTTESLEAEIVVHSDSKYHLKKRISSLTLPIVPS SEASKVLSRTPILPSTPVTPPLLLPAIGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEV SSTVE hide sequence

RefSeq Acc Id:	XP_006246190 ⟸ XM_006246128
- Peptide Label:	isoform X1
- UniProtKB:	P30191 (UniProtKB/Swiss-Prot), A6HDL7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLLLLPWLFSLLWIENAQAQLEDEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYV TSFGPVSDVEMTWTDERLKFKGPAEILSLNNLMVSKIWTPDTFFQNGKKSIAHNMTTPNKLFRL MQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEES SSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINK ESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNL QSQKAERQAQTAAKPPVAKSKTTESLEAEIVVHSDSKYHLKKRISSLTLPIVPSSEASKVLSRT PILPSTPVTPPLLLPAIGGTSKIDQYSRILFPVAFAGFNLVYWIVYLSKDTMEVSSTVE hide sequence

Ensembl Acc Id:

ENSRNOP00000004877 ⟸ ENSRNOT00000004877

Protein Domains

Neurotransmitter-gated ion-channel ligand-binding Neurotransmitter-gated ion-channel transmembrane

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P30191-F1-model_v2	AlphaFold	P30191	1-453	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697110

Promoter ID:

EPDNEW_R7635

Type:

single initiation site

Name:

Gabra6_1

Description:

gamma-aminobutyric acid type A receptor alpha 6 subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	27,862,789 - 27,862,849	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:61861	AgrOrtholog
BioCyc Gene	G2FUF-25471	BioCyc
Ensembl Genes	ENSRNOG00000003569	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000004877	ENTREZGENE
Gene3D-CATH	1.20.58.390	UniProtKB/Swiss-Prot
	2.70.170.10	UniProtKB/Swiss-Prot
InterPro	GABAA/Glycine_rcpt	UniProtKB/Swiss-Prot
	GABAAa_rcpt	UniProtKB/Swiss-Prot
	GABBAa6_rcpt	UniProtKB/Swiss-Prot
	Gabra-1-6_TM	UniProtKB/Swiss-Prot
	Neur_chan_lig-bd	UniProtKB/Swiss-Prot
	Neur_chan_lig-bd_sf	UniProtKB/Swiss-Prot
	Neur_channel	UniProtKB/Swiss-Prot
	Neuro-gated_channel_TM_sf	UniProtKB/Swiss-Prot
	Neuro_actylchol_rec	UniProtKB/Swiss-Prot
	Neurotrans-gated_channel_TM	UniProtKB/Swiss-Prot
	Neurotransmitter_ion_chnl_CS	UniProtKB/Swiss-Prot
KEGG Report	rno:29708	UniProtKB/Swiss-Prot
NCBI Gene	29708	ENTREZGENE
PANTHER	PTHR18945	UniProtKB/Swiss-Prot
Pfam	Neur_chan_LBD	UniProtKB/Swiss-Prot
	Neur_chan_memb	UniProtKB/Swiss-Prot
PhenoGen	Gabra6	PhenoGen
PRINTS	GABAARALPHA	UniProtKB/Swiss-Prot
	GABAARALPHA6	UniProtKB/Swiss-Prot
	GABAARECEPTR	UniProtKB/Swiss-Prot
	NRIONCHANNEL	UniProtKB/Swiss-Prot
PROSITE	NEUROTR_ION_CHANNEL	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000003569	RatGTEx
Superfamily-SCOP	SSF63712	UniProtKB/Swiss-Prot
	SSF90112	UniProtKB/Swiss-Prot
UniProt	A6HDL7	ENTREZGENE, UniProtKB/TrEMBL
	A6HDL8	ENTREZGENE, UniProtKB/TrEMBL
	G3V6G3	ENTREZGENE, UniProtKB/TrEMBL
	GBRA6_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-12-06	Gabra6	gamma-aminobutyric acid type A receptor subunit alpha6	Gabra6	gamma-aminobutyric acid type A receptor alpha 6 subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-02-11	Gabra6	gamma-aminobutyric acid type A receptor alpha 6 subunit	Gabra6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-04	Gabra6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	Gabra6	gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Gabra6	gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6		gamma-aminobutyric acid A receptor, alpha 6	Name updated	1299863	APPROVED
2002-06-10	Gabra6	gamma-aminobutyric acid A receptor, alpha 6			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	differentially expressed in the central nervous system	61594

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Mammalian Phenotype

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Mammalian Phenotype