Symbol:
Fdft1
Name:
farnesyl diphosphate farnesyl transferase 1
RGD ID:
61834
Description:
Predicted to enable squalene synthase [NAD(P)H] activity. Involved in cholesterol biosynthetic process and farnesyl diphosphate metabolic process. Located in endoplasmic reticulum membrane. Used to study cataract. Orthologous to human FDFT1 (farnesyl-diphosphate farnesyltransferase 1); PARTICIPATES IN cholesterol biosynthetic pathway; alendronate pharmacodynamics pathway; cholesterol ester storage disease pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 1-(3-(trifluoromethyl)phenyl)piperazine; 1-benzylpiperazine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
farnesyl diphosphate farnesyltransferase; farnesyl-diphosphate farnesyltransferase; FPP:FPP farnesyltransferase; MGC93486; SQS; squalene synthase; squalene synthetase; SS
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
FDFT1 (farnesyl-diphosphate farnesyltransferase 1) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Fdft1 (farnesyl diphosphate farnesyl transferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Fdft1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
FDFT1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
FDFT1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Fdft1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
FDFT1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
FDFT1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Fdft1 (farnesyl-diphosphate farnesyltransferase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Fdft1 (farnesyl diphosphate farnesyl transferase 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Homo sapiens (human):
FDFT1 (farnesyl-diphosphate farnesyltransferase 1)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
fdft1 (farnesyl-diphosphate farnesyltransferase 1)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
ERG9
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Is Marker For:
Strains:
SCR/Sscr
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 15 41,588,114 - 41,616,168 (-) NCBI GRCr8 mRatBN7.2 15 37,412,143 - 37,440,198 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 15 37,412,146 - 37,440,287 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 15 39,264,820 - 39,292,948 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 15 40,415,629 - 40,443,757 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 15 38,872,774 - 38,900,828 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 15 46,339,248 - 46,367,302 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 46,339,249 - 46,367,302 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 15 50,104,042 - 50,132,096 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 42,425,336 - 42,453,390 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 15 42,442,550 - 42,469,109 (-) NCBI Celera 15 37,096,417 - 37,124,524 (-) NCBI Celera Cytogenetic Map 15 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Fdft1 Rat 1,2,4-trimethylbenzene decreases expression EXP 6480464 pseudocumene results in decreased expression of FDFT1 protein CTD PMID:17337753 Fdft1 Rat 1,2-dimethylhydrazine multiple interactions ISO Fdft1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDFT1 mRNA CTD PMID:22206623 Fdft1 Rat 1-(3-(trifluoromethyl)phenyl)piperazine increases expression EXP 6480464 1-(3-trifluoromethylphenyl)piperazine results in increased expression of FDFT1 mRNA CTD PMID:26821219 Fdft1 Rat 1-benzylpiperazine increases expression EXP 6480464 N-benzylpiperazine results in increased expression of FDFT1 mRNA CTD PMID:26821219 Fdft1 Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of FDFT1 mRNA CTD PMID:30723492 Fdft1 Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of FDFT1 mRNA CTD PMID:16174780 Fdft1 Rat 17alpha-ethynylestradiol multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Ethinyl Estradiol co-treated with Cholic Acids] affects the expression of FDFT1 mRNA CTD PMID:27344345 Fdft1 Rat 17beta-estradiol increases expression ISO Fdft1 (Mus musculus) 6480464 Estradiol results in increased expression of FDFT1 mRNA CTD PMID:14664709 and PMID:39298647 Fdft1 Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of FDFT1 mRNA CTD PMID:32145629 Fdft1 Rat 17beta-estradiol decreases expression ISO Fdft1 (Mus musculus) 6480464 Estradiol results in decreased expression of FDFT1 mRNA CTD PMID:19484750 Fdft1 Rat 17beta-estradiol increases expression ISO FDFT1 (Homo sapiens) 6480464 Estradiol results in increased expression of FDFT1 mRNA CTD PMID:19167446 Fdft1 Rat 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO FDFT1 (Homo sapiens) 6480464 Metribolone results in increased expression of FDFT1 mRNA and Metribolone results in increased expression of FDFT1 protein CTD PMID:17483544 Fdft1 Rat 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO FDFT1 (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of FDFT1 mRNA CTD PMID:29581250 Fdft1 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Fdft1 Rat 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO Fdft1 (Mus musculus) 6480464 2 more ... CTD PMID:30294300 Fdft1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Fdft1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of FDFT1 mRNA CTD PMID:19770486 Fdft1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO FDFT1 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of FDFT1 protein CTD PMID:31225620 Fdft1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Fdft1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of FDFT1 mRNA CTD PMID:28213091 and PMID:28238261 Fdft1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28213091 and PMID:28433925 Fdft1 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Fdft1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of FDFT1 mRNA CTD PMID:28922406 Fdft1 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of FDFT1 mRNA CTD PMID:16960034 more ... Fdft1 Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Fdft1 Rat 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Fdft1 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 Fdft1 Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of FDFT1 mRNA CTD PMID:21346803 Fdft1 Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of FDFT1 mRNA CTD PMID:21346803 Fdft1 Rat 22-Hydroxycholesterol decreases expression ISO FDFT1 (Homo sapiens) 6480464 22-hydroxycholesterol results in decreased expression of FDFT1 mRNA CTD PMID:19426978 Fdft1 Rat 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of FDFT1 mRNA CTD PMID:15953391 Fdft1 Rat 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of FDFT1 mRNA CTD PMID:19162173 Fdft1 Rat 4,4'-sulfonyldiphenol affects expression ISO Fdft1 (Mus musculus) 6480464 bisphenol S affects the expression of FDFT1 mRNA CTD PMID:39298647 Fdft1 Rat 4,4'-sulfonyldiphenol increases expression ISO Fdft1 (Mus musculus) 6480464 bisphenol S results in increased expression of FDFT1 mRNA CTD PMID:34850234 Fdft1 Rat 4,4'-sulfonyldiphenol increases expression ISO FDFT1 (Homo sapiens) 6480464 bisphenol S results in increased expression of FDFT1 protein CTD PMID:34186270 Fdft1 Rat 5-aza-2'-deoxycytidine affects expression ISO FDFT1 (Homo sapiens) 6480464 Decitabine affects the expression of FDFT1 mRNA CTD PMID:23300844 Fdft1 Rat 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression EXP 6480464 Omeprazole affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:30611723 Fdft1 Rat 6-propyl-2-thiouracil affects expression EXP 6480464 Propylthiouracil affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of FDFT1 mRNA CTD PMID:24780913 Fdft1 Rat 8-Br-cAMP increases expression ISO FDFT1 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of FDFT1 mRNA CTD PMID:22079614 Fdft1 Rat 9-cis-retinoic acid increases expression EXP 6480464 Alitretinoin results in increased expression of FDFT1 mRNA CTD PMID:16648578 Fdft1 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of FDFT1 mRNA CTD PMID:31881176 Fdft1 Rat acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of FDFT1 mRNA CTD PMID:12800193 Fdft1 Rat acrolein multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of and affects the oxidation of FDFT1 mRNA more ... CTD PMID:32699268 and PMID:32845096 Fdft1 Rat aflatoxin B1 decreases expression ISO Fdft1 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of FDFT1 mRNA CTD PMID:19770486 Fdft1 Rat aflatoxin B1 decreases expression ISO FDFT1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased expression of FDFT1 mRNA CTD PMID:27153756 Fdft1 Rat all-trans-retinoic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 Tretinoin results in decreased expression of FDFT1 mRNA CTD PMID:23724009 Fdft1 Rat all-trans-retinoic acid increases expression ISO FDFT1 (Homo sapiens) 6480464 Tretinoin results in increased expression of FDFT1 mRNA CTD PMID:33167477 Fdft1 Rat alpha-pinene multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of and affects the oxidation of FDFT1 mRNA more ... CTD PMID:32699268 Fdft1 Rat aluminium atom increases expression ISO Fdft1 (Mus musculus) 6480464 Aluminum results in increased expression of FDFT1 mRNA CTD PMID:37544489 Fdft1 Rat aluminium(0) increases expression ISO Fdft1 (Mus musculus) 6480464 Aluminum results in increased expression of FDFT1 mRNA CTD PMID:37544489 Fdft1 Rat amiodarone affects expression EXP 6480464 Amiodarone affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of FDFT1 mRNA CTD PMID:22291062 Fdft1 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of FDFT1 mRNA CTD PMID:16483693 Fdft1 Rat antimony(0) decreases expression ISO FDFT1 (Homo sapiens) 6480464 Antimony results in decreased expression of FDFT1 mRNA CTD PMID:17547211 Fdft1 Rat Archazolid B increases expression ISO FDFT1 (Homo sapiens) 6480464 archazolid B results in increased expression of FDFT1 mRNA CTD PMID:25218289 Fdft1 Rat aristolochic acid A decreases expression ISO FDFT1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of FDFT1 mRNA and aristolochic acid I results in decreased expression of FDFT1 protein CTD PMID:33212167 Fdft1 Rat arsane multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of FDFT1 mRNA CTD PMID:39836092 Fdft1 Rat arsenic atom multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of FDFT1 mRNA CTD PMID:39836092 Fdft1 Rat arsenite(3-) multiple interactions ISO FDFT1 (Homo sapiens) 6480464 arsenite promotes the reaction [G3BP1 protein binds to FDFT1 mRNA] CTD PMID:32406909 Fdft1 Rat avobenzone increases expression ISO FDFT1 (Homo sapiens) 6480464 avobenzone results in increased expression of FDFT1 mRNA CTD PMID:31016361 Fdft1 Rat Azaspiracid increases expression ISO FDFT1 (Homo sapiens) 6480464 azaspiracid results in increased expression of FDFT1 mRNA CTD PMID:28939011 Fdft1 Rat azoxystrobin increases expression ISO FDFT1 (Homo sapiens) 6480464 azoxystrobin results in increased expression of FDFT1 mRNA CTD PMID:33512557 Fdft1 Rat benzbromarone affects expression EXP 6480464 Benzbromarone affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat benzene decreases expression ISO FDFT1 (Homo sapiens) 6480464 Benzene results in decreased expression of FDFT1 mRNA CTD PMID:19162166 Fdft1 Rat benzo[a]pyrene decreases expression ISO FDFT1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of FDFT1 mRNA CTD PMID:21632981 and PMID:32234424 Fdft1 Rat beta-lapachone increases expression ISO FDFT1 (Homo sapiens) 6480464 beta-lapachone results in increased expression of FDFT1 mRNA CTD PMID:38218311 Fdft1 Rat beta-lapachone decreases expression ISO FDFT1 (Homo sapiens) 6480464 beta-lapachone results in decreased expression of FDFT1 mRNA CTD PMID:38218311 Fdft1 Rat beta-naphthoflavone multiple interactions ISO FDFT1 (Homo sapiens) 6480464 AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA] CTD PMID:22234961 Fdft1 Rat beta-naphthoflavone decreases expression ISO Fdft1 (Mus musculus) 6480464 beta-Naphthoflavone results in decreased expression of FDFT1 mRNA CTD PMID:22234961 Fdft1 Rat beta-naphthoflavone multiple interactions ISO Fdft1 (Mus musculus) 6480464 AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA] CTD PMID:22234961 Fdft1 Rat beta-naphthoflavone decreases expression ISO FDFT1 (Homo sapiens) 6480464 beta-Naphthoflavone results in decreased expression of FDFT1 mRNA CTD PMID:22234961 Fdft1 Rat bexarotene increases expression EXP 6480464 bexarotene results in increased expression of FDFT1 mRNA CTD PMID:16648578 Fdft1 Rat bis(2-ethylhexyl) phthalate increases expression ISO Fdft1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of FDFT1 mRNA CTD PMID:19850644 Fdft1 Rat bis(2-ethylhexyl) phthalate multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Fdft1 Rat bisphenol A increases expression ISO Fdft1 (Mus musculus) 6480464 bisphenol A results in increased expression of FDFT1 mRNA CTD PMID:25270620 Fdft1 Rat bisphenol A decreases expression ISO FDFT1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of FDFT1 protein CTD PMID:37567409 Fdft1 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of FDFT1 mRNA CTD PMID:30816183 more ... Fdft1 Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of FDFT1 mRNA CTD PMID:30903817 Fdft1 Rat bisphenol A increases expression ISO FDFT1 (Homo sapiens) 6480464 bisphenol A results in increased expression of FDFT1 mRNA and bisphenol A results in increased expression of FDFT1 protein CTD PMID:29275510 and PMID:34186270 Fdft1 Rat bisphenol A affects expression ISO FDFT1 (Homo sapiens) 6480464 bisphenol A affects the expression of FDFT1 mRNA CTD PMID:30903817 Fdft1 Rat bisphenol A multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 Fdft1 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of FDFT1 mRNA CTD PMID:25181051 and PMID:31771501 Fdft1 Rat bromobenzene decreases expression EXP 6480464 bromobenzene results in decreased expression of FDFT1 mRNA CTD PMID:15056800 and PMID:32479839 Fdft1 Rat butan-1-ol multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of FDFT1 mRNA CTD PMID:29432896 Fdft1 Rat caffeine decreases expression EXP 6480464 Caffeine results in decreased expression of FDFT1 mRNA CTD PMID:20864626 Fdft1 Rat caffeine decreases phosphorylation ISO FDFT1 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of FDFT1 protein CTD PMID:35688186 Fdft1 Rat caffeine increases expression EXP 6480464 Caffeine results in increased expression of FDFT1 mRNA CTD PMID:25868845 Fdft1 Rat capsaicin increases expression ISO FDFT1 (Homo sapiens) 6480464 Capsaicin results in increased expression of FDFT1 mRNA CTD PMID:33512557 Fdft1 Rat captan increases expression ISO Fdft1 (Mus musculus) 6480464 Captan results in increased expression of FDFT1 mRNA CTD PMID:31558096 Fdft1 Rat carbamazepine affects expression ISO FDFT1 (Homo sapiens) 6480464 Carbamazepine affects the expression of FDFT1 mRNA CTD PMID:25979313 Fdft1 Rat carbon nanotube decreases expression ISO Fdft1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25620056 Fdft1 Rat carbon nanotube increases expression ISO Fdft1 (Mus musculus) 6480464 Nanotubes and Carbon results in increased expression of FDFT1 mRNA CTD PMID:25554681 Fdft1 Rat chloropicrin increases expression ISO FDFT1 (Homo sapiens) 6480464 chloropicrin results in increased expression of FDFT1 mRNA CTD PMID:26352163 Fdft1 Rat chlorpyrifos increases expression ISO Fdft1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of FDFT1 mRNA CTD PMID:37019170 Fdft1 Rat cholesterol increases chemical synthesis ISO FDFT1 (Homo sapiens) 6480464 FDFT1 protein results in increased chemical synthesis of Cholesterol CTD PMID:17483544 Fdft1 Rat chromium(6+) affects expression ISO Fdft1 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of FDFT1 mRNA CTD PMID:28472532 Fdft1 Rat ciguatoxin CTX1B affects expression ISO Fdft1 (Mus musculus) 6480464 Ciguatoxins affects the expression of FDFT1 mRNA CTD PMID:18353800 Fdft1 Rat cisplatin multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of FDFT1 mRNA and Cisplatin promotes the reaction [Piroxicam results in decreased expression of FDFT1 mRNA] CTD PMID:21858171 and PMID:27392435 Fdft1 Rat cisplatin decreases expression ISO FDFT1 (Homo sapiens) 6480464 Cisplatin results in decreased expression of FDFT1 mRNA CTD PMID:27594783 Fdft1 Rat cisplatin affects expression ISO FDFT1 (Homo sapiens) 6480464 Cisplatin affects the expression of FDFT1 mRNA CTD PMID:23300844 Fdft1 Rat cisplatin increases expression ISO Fdft1 (Mus musculus) 6480464 Cisplatin results in increased expression of FDFT1 mRNA CTD PMID:21151649 Fdft1 Rat clobetasol increases expression ISO Fdft1 (Mus musculus) 6480464 Clobetasol results in increased expression of FDFT1 mRNA CTD PMID:27462272 Fdft1 Rat clofibrate affects expression EXP 6480464 Clofibrate affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat cocaine increases expression ISO FDFT1 (Homo sapiens) 6480464 Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 Fdft1 Rat copper atom decreases expression EXP 6480464 Copper results in decreased expression of FDFT1 mRNA CTD PMID:22465980 Fdft1 Rat copper atom decreases expression ISO Fdft1 (Mus musculus) 6480464 Copper results in decreased expression of FDFT1 mRNA CTD PMID:17205981 Fdft1 Rat copper(0) decreases expression EXP 6480464 Copper results in decreased expression of FDFT1 mRNA CTD PMID:22465980 Fdft1 Rat copper(0) decreases expression ISO Fdft1 (Mus musculus) 6480464 Copper results in decreased expression of FDFT1 mRNA CTD PMID:17205981 Fdft1 Rat copper(II) chloride decreases expression ISO FDFT1 (Homo sapiens) 6480464 cupric chloride results in decreased expression of FDFT1 mRNA CTD PMID:34921933 Fdft1 Rat copper(II) sulfate decreases expression ISO FDFT1 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of FDFT1 mRNA CTD PMID:19549813 Fdft1 Rat copper(II) sulfate increases expression ISO FDFT1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of FDFT1 mRNA CTD PMID:12860252 Fdft1 Rat coumestrol multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 Fdft1 Rat coumestrol increases expression ISO FDFT1 (Homo sapiens) 6480464 Coumestrol results in increased expression of FDFT1 mRNA CTD PMID:19167446 Fdft1 Rat curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of FDFT1 mRNA CTD PMID:27208389 Fdft1 Rat cyclosporin A multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of FDFT1 mRNA CTD PMID:27344345 Fdft1 Rat cyclosporin A decreases expression ISO FDFT1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of FDFT1 mRNA CTD PMID:20106945 and PMID:25562108 Fdft1 Rat cyproconazole affects expression ISO Fdft1 (Mus musculus) 6480464 cyproconazole affects the expression of FDFT1 mRNA CTD PMID:22045034 Fdft1 Rat deoxynivalenol decreases expression ISO FDFT1 (Homo sapiens) 6480464 deoxynivalenol results in decreased expression of FDFT1 protein CTD PMID:33890134 Fdft1 Rat dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of FDFT1 mRNA CTD PMID:14618091 Fdft1 Rat dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of FDFT1 mRNA CTD PMID:17379624 more ... Fdft1 Rat dichloromethane affects expression ISO Fdft1 (Mus musculus) 6480464 Methylene Chloride affects the expression of FDFT1 mRNA CTD PMID:28392392 Fdft1 Rat difenoconazole increases expression EXP 6480464 difenoconazole results in increased expression of FDFT1 mRNA CTD PMID:28263823 Fdft1 Rat dimethylarsinic acid multiple interactions ISO Fdft1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FDFT1 mRNA CTD PMID:34876320 Fdft1 Rat dinophysistoxin 1 decreases expression ISO FDFT1 (Homo sapiens) 6480464 dinophysistoxin 1 results in decreased expression of FDFT1 mRNA CTD PMID:28939011 Fdft1 Rat dioxygen multiple interactions ISO Fdft1 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of FDFT1 mRNA CTD PMID:30529165 Fdft1 Rat dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate decreases expression ISO FDFT1 (Homo sapiens) 6480464 Antimony Potassium Tartrate results in decreased expression of FDFT1 mRNA CTD PMID:17547211 Fdft1 Rat diuron decreases expression ISO FDFT1 (Homo sapiens) 6480464 Diuron results in decreased expression of FDFT1 mRNA CTD PMID:35967413 Fdft1 Rat dorsomorphin multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Fdft1 Rat doxorubicin decreases response to substance ISO FDFT1 (Homo sapiens) 6480464 FDFT1 mRNA results in decreased susceptibility to Doxorubicin CTD PMID:16322897 Fdft1 Rat elemental selenium increases expression ISO Fdft1 (Mus musculus) 6480464 Selenium deficiency results in increased expression of FDFT1 mRNA CTD PMID:16170372 Fdft1 Rat endosulfan affects expression EXP 6480464 Endosulfan affects the expression of FDFT1 mRNA CTD PMID:29391264 Fdft1 Rat Enterolactone multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of FDFT1 mRNA CTD PMID:19167446 Fdft1 Rat entinostat decreases expression ISO FDFT1 (Homo sapiens) 6480464 entinostat results in decreased expression of FDFT1 mRNA CTD PMID:27188386 Fdft1 Rat epoxiconazole increases expression ISO FDFT1 (Homo sapiens) 6480464 epoxiconazole results in increased expression of FDFT1 mRNA CTD PMID:34182286 Fdft1 Rat ethanol increases expression ISO Fdft1 (Mus musculus) 6480464 Ethanol results in increased expression of FDFT1 mRNA CTD PMID:19167417 Fdft1 Rat ethanol affects expression ISO Fdft1 (Mus musculus) 6480464 Ethanol affects the expression of FDFT1 mRNA CTD PMID:30319688 Fdft1 Rat ethanol multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of FDFT1 mRNA CTD PMID:29432896 Fdft1 Rat ethyl methanesulfonate decreases expression ISO FDFT1 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in decreased expression of FDFT1 mRNA CTD PMID:23649840 Fdft1 Rat etoposide affects response to substance ISO FDFT1 (Homo sapiens) 6480464 FDFT1 protein affects the susceptibility to Etoposide CTD PMID:16217747 Fdft1 Rat farnesol increases expression ISO FDFT1 (Homo sapiens) 6480464 Farnesol analog results in increased expression of FDFT1 mRNA CTD PMID:30611723 Fdft1 Rat fenarimol increases expression EXP 6480464 fenarimol results in increased expression of FDFT1 mRNA CTD PMID:28970091 Fdft1 Rat fenofibrate increases expression ISO Fdft1 (Mus musculus) 6480464 Fenofibrate results in increased expression of FDFT1 mRNA CTD PMID:23063693 Fdft1 Rat fenofibrate multiple interactions ISO Fdft1 (Mus musculus) 6480464 NR1H2 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA] and NR1H3 gene mutant form inhibits the reaction [Fenofibrate results in increased expression of FDFT1 mRNA] CTD PMID:23063693 Fdft1 Rat flavonoids increases expression ISO FDFT1 (Homo sapiens) 6480464 Flavonoids results in increased expression of FDFT1 mRNA CTD PMID:37167442 Fdft1 Rat fluoranthene decreases expression ISO Fdft1 (Mus musculus) 6480464 fluoranthene results in decreased expression of FDFT1 mRNA CTD PMID:28329830 Fdft1 Rat fluoranthene multiple interactions ISO Fdft1 (Mus musculus) 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of FDFT1 mRNA CTD PMID:28329830 Fdft1 Rat fluoxetine increases expression ISO FDFT1 (Homo sapiens) 6480464 Fluoxetine results in increased expression of FDFT1 mRNA CTD PMID:37386098 Fdft1 Rat flusilazole affects expression ISO Fdft1 (Mus musculus) 6480464 flusilazole affects the expression of FDFT1 mRNA CTD PMID:21195148 Fdft1 Rat flusilazole increases expression EXP 6480464 flusilazole results in increased expression of FDFT1 mRNA CTD PMID:22664269 and PMID:28263823 Fdft1 Rat fluvastatin multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [zoledronic acid co-treated with fluvastatin] results in increased expression of FDFT1 mRNA CTD PMID:16996129 Fdft1 Rat folic acid multiple interactions ISO Fdft1 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of FDFT1 mRNA CTD PMID:22206623 Fdft1 Rat folpet increases expression ISO Fdft1 (Mus musculus) 6480464 folpet results in increased expression of FDFT1 mRNA CTD PMID:31558096 Fdft1 Rat formaldehyde decreases expression ISO FDFT1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of FDFT1 mRNA CTD PMID:23649840 Fdft1 Rat fumonisin B1 decreases expression ISO Fdft1 (Mus musculus) 6480464 fumonisin B1 results in decreased expression of FDFT1 mRNA CTD PMID:16221962 Fdft1 Rat Ganoderic acid A decreases expression ISO FDFT1 (Homo sapiens) 6480464 ganoderic acid A results in decreased expression of FDFT1 mRNA CTD PMID:29852127 Fdft1 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of FDFT1 mRNA CTD PMID:33387578 Fdft1 Rat GW 4064 multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [GW 4064 co-treated with Oleic Acid] results in decreased expression of FDFT1 mRNA CTD PMID:30611723 Fdft1 Rat hexaconazole affects expression ISO Fdft1 (Mus musculus) 6480464 hexaconazole affects the expression of FDFT1 mRNA CTD PMID:21195148 and PMID:22045034 Fdft1 Rat hydrogen peroxide multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 Fdft1 Rat isoflavones increases expression ISO FDFT1 (Homo sapiens) 6480464 Isoflavones results in increased expression of FDFT1 mRNA CTD PMID:17374662 Fdft1 Rat isotretinoin decreases expression ISO FDFT1 (Homo sapiens) 6480464 Isotretinoin results in decreased expression of FDFT1 mRNA CTD PMID:20436886 Fdft1 Rat ivermectin decreases expression ISO FDFT1 (Homo sapiens) 6480464 Ivermectin results in decreased expression of FDFT1 protein CTD PMID:32959892 Fdft1 Rat ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of FDFT1 mRNA CTD PMID:20080153 Fdft1 Rat ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of FDFT1 mRNA CTD PMID:28263823 Fdft1 Rat L-ethionine affects expression EXP 6480464 Ethionine affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat lead nitrate increases expression EXP 6480464 lead nitrate results in increased expression of FDFT1 mRNA CTD PMID:15475176 Fdft1 Rat lead(0) decreases expression ISO FDFT1 (Homo sapiens) 6480464 Lead results in decreased expression of FDFT1 mRNA CTD PMID:19921347 Fdft1 Rat leflunomide decreases expression ISO FDFT1 (Homo sapiens) 6480464 leflunomide results in decreased expression of FDFT1 mRNA CTD PMID:28988120 Fdft1 Rat leflunomide decreases expression ISO Fdft1 (Mus musculus) 6480464 leflunomide results in decreased expression of FDFT1 mRNA CTD PMID:19751817 Fdft1 Rat lovastatin increases activity ISO FDFT1 (Homo sapiens) 6480464 Lovastatin results in increased activity of FDFT1 protein CTD PMID:8517861 Fdft1 Rat maneb multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of FDFT1 mRNA CTD PMID:36117858 Fdft1 Rat methidathion decreases expression ISO Fdft1 (Mus musculus) 6480464 methidathion results in decreased expression of FDFT1 mRNA CTD PMID:34813904 Fdft1 Rat methyl methanesulfonate decreases expression ISO FDFT1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in decreased expression of FDFT1 mRNA CTD PMID:23649840 Fdft1 Rat methylarsonic acid multiple interactions ISO Fdft1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FDFT1 mRNA CTD PMID:34876320 Fdft1 Rat methylmercury chloride increases expression ISO FDFT1 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of FDFT1 mRNA CTD PMID:28001369 Fdft1 Rat miconazole increases expression ISO Fdft1 (Mus musculus) 6480464 Miconazole results in increased expression of FDFT1 mRNA CTD PMID:27462272 Fdft1 Rat mitomycin C affects response to substance ISO FDFT1 (Homo sapiens) 6480464 FDFT1 protein affects the susceptibility to Mitomycin CTD PMID:16217747 Fdft1 Rat mitoxantrone affects response to substance ISO FDFT1 (Homo sapiens) 6480464 FDFT1 protein affects the susceptibility to Mitoxantrone CTD PMID:16217747 Fdft1 Rat N-ethyl-N-nitrosourea decreases expression EXP 6480464 Ethylnitrosourea results in decreased expression of FDFT1 mRNA CTD PMID:15954086 Fdft1 Rat N-methyl-4-phenylpyridinium increases expression ISO FDFT1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of FDFT1 mRNA CTD PMID:24810058 Fdft1 Rat N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of FDFT1 mRNA CTD PMID:19638242 Fdft1 Rat N-nitrosodimethylamine decreases expression ISO FDFT1 (Homo sapiens) 6480464 Dimethylnitrosamine results in decreased expression of FDFT1 mRNA CTD PMID:17547211 Fdft1 Rat okadaic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 Okadaic Acid results in decreased expression of FDFT1 mRNA CTD PMID:28939011 Fdft1 Rat oleic acid multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:30611723 Fdft1 Rat omeprazole affects expression EXP 6480464 Omeprazole affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat ozone decreases expression EXP 6480464 Ozone results in decreased expression of FDFT1 mRNA CTD PMID:16716893 Fdft1 Rat ozone multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of FDFT1 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of FDFT1 mRNA CTD PMID:27106289 and PMID:34911549 Fdft1 Rat ozone multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] affects the expression of and affects the oxidation of FDFT1 mRNA more ... CTD PMID:32699268 and PMID:32845096 Fdft1 Rat p-chloromercuribenzoic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in decreased expression of FDFT1 mRNA CTD PMID:26272509 Fdft1 Rat p-chloromercuribenzoic acid multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FDFT1 mRNA CTD PMID:27188386 Fdft1 Rat paclitaxel affects response to substance ISO FDFT1 (Homo sapiens) 6480464 FDFT1 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 Fdft1 Rat paracetamol affects expression ISO Fdft1 (Mus musculus) 6480464 Acetaminophen affects the expression of FDFT1 mRNA CTD PMID:17562736 Fdft1 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of FDFT1 mRNA CTD PMID:32479839 and PMID:33387578 Fdft1 Rat paracetamol decreases expression ISO FDFT1 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of FDFT1 mRNA CTD PMID:29067470 Fdft1 Rat paracetamol increases expression ISO Fdft1 (Mus musculus) 6480464 Acetaminophen results in increased expression of FDFT1 mRNA CTD PMID:29246445 Fdft1 Rat paracetamol multiple interactions ISO Fdft1 (Mus musculus) 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of FDFT1 mRNA] CTD PMID:29246445 Fdft1 Rat paracetamol decreases expression ISO Fdft1 (Mus musculus) 6480464 Acetaminophen results in decreased expression of FDFT1 mRNA CTD PMID:11264010 Fdft1 Rat paraquat multiple interactions ISO Fdft1 (Mus musculus) 6480464 [Maneb co-treated with Paraquat] results in decreased expression of FDFT1 mRNA CTD PMID:36117858 Fdft1 Rat perfluorobutanesulfonic acid decreases expression EXP 6480464 perfluorobutanesulfonic acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorobutyric acid decreases expression EXP 6480464 perfluorobutyric acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorododecanoic acid increases expression EXP 6480464 perfluorododecanoic acid results in increased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorohexanesulfonic acid increases expression ISO Fdft1 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of FDFT1 mRNA CTD PMID:21705711 Fdft1 Rat perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorohexanoic acid increases expression EXP 6480464 perfluorohexanoic acid results in increased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorononanoic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:32588087 Fdft1 Rat perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorooctane-1-sulfonic acid increases expression ISO Fdft1 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of FDFT1 mRNA CTD PMID:19429403 and PMID:20936131 Fdft1 Rat perfluorooctane-1-sulfonic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of FDFT1 mRNA CTD PMID:36864359 and PMID:38199259 Fdft1 Rat perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:19162173 Fdft1 Rat perfluorooctanoic acid decreases expression ISO Fdft1 (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:30508572 Fdft1 Rat perfluorooctanoic acid increases expression ISO FDFT1 (Homo sapiens) 6480464 perfluorooctanoic acid results in increased expression of FDFT1 mRNA CTD PMID:23978341 and PMID:25868421 Fdft1 Rat perfluorooctanoic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of FDFT1 mRNA and perfluorooctanoic acid results in decreased expression of FDFT1 protein CTD PMID:25868421 and PMID:26879310 Fdft1 Rat perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat perfluorooctanoic acid increases expression ISO Fdft1 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of FDFT1 mRNA CTD PMID:19429403 Fdft1 Rat perfluoroundecanoic acid decreases expression EXP 6480464 perfluoroundecanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 Fdft1 Rat phencyclidine increases expression ISO FDFT1 (Homo sapiens) 6480464 Phencyclidine results in increased expression of FDFT1 mRNA CTD PMID:17205118 Fdft1 Rat phenobarbital multiple interactions ISO Fdft1 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of FDFT1 mRNA] CTD PMID:19482888 Fdft1 Rat phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of FDFT1 mRNA CTD PMID:19162173 Fdft1 Rat phenobarbital increases expression ISO Fdft1 (Mus musculus) 6480464 Phenobarbital results in increased expression of FDFT1 mRNA CTD PMID:19482888 Fdft1 Rat phenobarbital decreases expression ISO Fdft1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of FDFT1 mRNA CTD PMID:19270015 Fdft1 Rat phenylmercury acetate decreases expression ISO FDFT1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in decreased expression of FDFT1 mRNA CTD PMID:26272509 Fdft1 Rat phenylmercury acetate multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of FDFT1 mRNA CTD PMID:27188386 Fdft1 Rat phenylpropanolamine increases expression ISO FDFT1 (Homo sapiens) 6480464 Phenylpropanolamine results in increased expression of FDFT1 mRNA CTD PMID:27756839 Fdft1 Rat phosgene affects expression ISO Fdft1 (Mus musculus) 6480464 Phosgene affects the expression of FDFT1 mRNA CTD PMID:16300373 Fdft1 Rat picoxystrobin increases expression ISO FDFT1 (Homo sapiens) 6480464 picoxystrobin results in increased expression of FDFT1 mRNA CTD PMID:33512557 Fdft1 Rat pirinixic acid multiple interactions ISO Fdft1 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FDFT1 mRNA more ... CTD PMID:15777286 more ... Fdft1 Rat pirinixic acid increases expression ISO Fdft1 (Mus musculus) 6480464 pirinixic acid results in increased expression of FDFT1 mRNA CTD PMID:15777286 more ... Fdft1 Rat pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of FDFT1 mRNA CTD PMID:19162173 Fdft1 Rat pirinixic acid affects expression EXP 6480464 pirinixic acid affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat pirinixic acid decreases expression ISO Fdft1 (Mus musculus) 6480464 pirinixic acid results in decreased expression of FDFT1 mRNA CTD PMID:18445702 Fdft1 Rat piroxicam multiple interactions ISO FDFT1 (Homo sapiens) 6480464 Cisplatin promotes the reaction [Piroxicam results in decreased expression of FDFT1 mRNA] CTD PMID:21858171 Fdft1 Rat piroxicam decreases expression ISO FDFT1 (Homo sapiens) 6480464 Piroxicam results in decreased expression of FDFT1 mRNA CTD PMID:21858171 Fdft1 Rat potassium dichromate increases expression ISO FDFT1 (Homo sapiens) 6480464 Potassium Dichromate results in increased expression of FDFT1 mRNA and Potassium Dichromate results in increased expression of FDFT1 protein CTD PMID:23718831 Fdft1 Rat pravastatin affects activity ISO FDFT1 (Homo sapiens) 6480464 Pravastatin affects the activity of FDFT1 protein CTD PMID:8517861 Fdft1 Rat pregnenolone 16alpha-carbonitrile decreases expression ISO Fdft1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in decreased expression of FDFT1 mRNA CTD PMID:28903501 Fdft1 Rat progesterone increases expression ISO FDFT1 (Homo sapiens) 6480464 Progesterone results in increased expression of FDFT1 mRNA CTD PMID:18070364 Fdft1 Rat propiconazole increases expression EXP 6480464 propiconazole results in increased expression of FDFT1 mRNA CTD PMID:28970091 Fdft1 Rat quercetin decreases expression ISO FDFT1 (Homo sapiens) 6480464 Quercetin results in decreased expression of FDFT1 mRNA CTD PMID:21632981 Fdft1 Rat quercetin multiple interactions ISO Fdft1 (Mus musculus) 6480464 Quercetin inhibits the reaction [Dietary Fats results in increased expression of FDFT1 mRNA] CTD PMID:22447684 Fdft1 Rat quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 Fdft1 Rat quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased expression of FDFT1 mRNA CTD PMID:18032389 Fdft1 Rat resveratrol increases expression ISO FDFT1 (Homo sapiens) 6480464 resveratrol results in increased expression of FDFT1 mRNA CTD PMID:22153697 Fdft1 Rat resveratrol decreases expression ISO Fdft1 (Mus musculus) 6480464 resveratrol results in decreased expression of FDFT1 mRNA CTD PMID:18930334 Fdft1 Rat resveratrol multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of FDFT1 mRNA and resveratrol inhibits the reaction [Simvastatin results in increased expression of FDFT1 mRNA] CTD PMID:19167446 and PMID:23386644 Fdft1 Rat rotenone affects expression EXP 6480464 Rotenone affects the expression of FDFT1 mRNA CTD PMID:28374803 Fdft1 Rat rotenone increases expression ISO FDFT1 (Homo sapiens) 6480464 Rotenone results in increased expression of FDFT1 mRNA CTD PMID:29955902 and PMID:33512557 Fdft1 Rat SB 431542 multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 Fdft1 Rat selenium atom increases expression ISO Fdft1 (Mus musculus) 6480464 Selenium deficiency results in increased expression of FDFT1 mRNA CTD PMID:16170372 Fdft1 Rat senecionine decreases expression ISO Fdft1 (Mus musculus) 6480464 senecionine results in decreased expression of FDFT1 protein CTD PMID:35357534 Fdft1 Rat simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of FDFT1 protein CTD PMID:12518039 Fdft1 Rat simvastatin increases expression ISO FDFT1 (Homo sapiens) 6480464 Simvastatin results in increased expression of FDFT1 mRNA CTD PMID:23386644 Fdft1 Rat simvastatin multiple interactions ISO FDFT1 (Homo sapiens) 6480464 resveratrol inhibits the reaction [Simvastatin results in increased expression of FDFT1 mRNA] CTD PMID:23386644 Fdft1 Rat simvastatin increases activity ISO FDFT1 (Homo sapiens) 6480464 Simvastatin results in increased activity of FDFT1 protein CTD PMID:8517861 Fdft1 Rat sodium arsenate multiple interactions ISO Fdft1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FDFT1 mRNA CTD PMID:34876320 Fdft1 Rat sodium arsenite increases expression ISO FDFT1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of FDFT1 mRNA CTD PMID:25524072 and PMID:34032870 Fdft1 Rat sodium arsenite multiple interactions ISO Fdft1 (Mus musculus) 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of FDFT1 mRNA CTD PMID:34876320 Fdft1 Rat sodium arsenite multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of FDFT1 mRNA CTD PMID:39836092 Fdft1 Rat sodium arsenite decreases expression ISO FDFT1 (Homo sapiens) 6480464 sodium arsenite results in decreased expression of FDFT1 mRNA CTD PMID:38568856 Fdft1 Rat Soman decreases expression EXP 6480464 Soman results in decreased expression of FDFT1 mRNA CTD PMID:19281266 Fdft1 Rat sunitinib increases expression ISO FDFT1 (Homo sapiens) 6480464 Sunitinib results in increased expression of FDFT1 mRNA CTD PMID:31533062 Fdft1 Rat tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of FDFT1 mRNA CTD PMID:31150632 Fdft1 Rat tetrachloromethane decreases expression ISO Fdft1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of FDFT1 mRNA CTD PMID:31919559 Fdft1 Rat tetracycline decreases expression ISO Fdft1 (Mus musculus) 6480464 Tetracycline results in decreased expression of FDFT1 mRNA CTD PMID:24489787 Fdft1 Rat thapsigargin decreases expression ISO FDFT1 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of FDFT1 mRNA CTD PMID:22378314 Fdft1 Rat Theaflavin 3,3'-digallate multiple interactions ISO Fdft1 (Mus musculus) 6480464 theaflavin-3 and 3'-digallate inhibits the reaction [LEP gene mutant form affects the expression of FDFT1 mRNA] CTD PMID:36105184 Fdft1 Rat thioacetamide affects expression EXP 6480464 Thioacetamide affects the expression of FDFT1 mRNA CTD PMID:19483382 Fdft1 Rat thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of FDFT1 mRNA CTD PMID:34492290 Fdft1 Rat titanium dioxide increases expression ISO Fdft1 (Mus musculus) 6480464 titanium dioxide results in increased expression of FDFT1 mRNA CTD PMID:27760801 and PMID:35295148 Fdft1 Rat titanium dioxide decreases methylation ISO Fdft1 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of FDFT1 promoter CTD PMID:35295148 Fdft1 Rat topotecan affects response to substance ISO FDFT1 (Homo sapiens) 6480464 FDFT1 protein affects the susceptibility to Topotecan CTD PMID:16217747 Fdft1 Rat triadimefon increases expression ISO Fdft1 (Mus musculus) 6480464 triadimefon results in increased expression of FDFT1 mRNA CTD PMID:17178688 Fdft1 Rat triadimefon affects expression ISO Fdft1 (Mus musculus) 6480464 triadimefon affects the expression of FDFT1 mRNA CTD PMID:21195148 Fdft1 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of FDFT1 mRNA CTD PMID:19448997 Fdft1 Rat trimellitic anhydride increases expression ISO Fdft1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of FDFT1 mRNA CTD PMID:19042947 Fdft1 Rat triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of FDFT1 mRNA CTD PMID:30589522 Fdft1 Rat triphenyl phosphate affects expression ISO FDFT1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of FDFT1 mRNA CTD PMID:37042841 Fdft1 Rat Triptolide increases expression EXP 6480464 triptolide results in increased expression of FDFT1 protein CTD PMID:32519852 Fdft1 Rat tunicamycin decreases expression ISO FDFT1 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of FDFT1 mRNA CTD PMID:22378314 and PMID:29453283 Fdft1 Rat undecane decreases expression EXP 6480464 undecane results in decreased expression of FDFT1 protein CTD PMID:17337753 Fdft1 Rat valproic acid increases expression ISO FDFT1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of FDFT1 mRNA CTD PMID:19101580 Fdft1 Rat valproic acid decreases methylation ISO FDFT1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of FDFT1 gene CTD PMID:29501571 Fdft1 Rat valproic acid decreases expression ISO FDFT1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of FDFT1 mRNA CTD PMID:23179753 and PMID:27188386 Fdft1 Rat valproic acid affects expression ISO Fdft1 (Mus musculus) 6480464 Valproic Acid affects the expression of FDFT1 mRNA CTD PMID:17292431 Fdft1 Rat valproic acid increases expression ISO Fdft1 (Mus musculus) 6480464 Valproic Acid results in increased expression of FDFT1 mRNA CTD PMID:20546886 Fdft1 Rat valproic acid decreases expression ISO Fdft1 (Mus musculus) 6480464 Valproic Acid results in decreased expression of FDFT1 mRNA CTD PMID:22045034 Fdft1 Rat valproic acid affects expression ISO FDFT1 (Homo sapiens) 6480464 Valproic Acid affects the expression of FDFT1 mRNA CTD PMID:25979313 Fdft1 Rat vincristine increases expression ISO FDFT1 (Homo sapiens) 6480464 Vincristine results in increased expression of FDFT1 mRNA CTD PMID:23649840 Fdft1 Rat vorinostat decreases expression ISO FDFT1 (Homo sapiens) 6480464 vorinostat results in decreased expression of FDFT1 mRNA CTD PMID:27188386 Fdft1 Rat Yessotoxin increases expression ISO FDFT1 (Homo sapiens) 6480464 yessotoxin analog results in increased expression of FDFT1 mRNA CTD PMID:30679557 Fdft1 Rat zoledronic acid multiple interactions ISO FDFT1 (Homo sapiens) 6480464 [zoledronic acid co-treated with fluvastatin] results in increased expression of FDFT1 mRNA CTD PMID:16996129 Fdft1 Rat zoledronic acid increases expression EXP 6480464 zoledronic acid results in increased expression of FDFT1 mRNA CTD PMID:18325729
Imported Annotations - SMPDB
Imported Annotations - KEGG (archival)
1,2,4-trimethylbenzene (EXP) 1,2-dimethylhydrazine (ISO) 1-(3-(trifluoromethyl)phenyl)piperazine (EXP) 1-benzylpiperazine (EXP) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP,ISO) 17beta-estradiol (EXP,ISO) 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO) 17beta-hydroxy-5alpha-androstan-3-one (ISO) 2,2',4,4',5,5'-hexachlorobiphenyl (ISO) 2,2',4,4'-Tetrabromodiphenyl ether (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,3,7,8-Tetrachlorodibenzofuran (EXP) 2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO) 2,4-dinitrotoluene (EXP) 2,6-dinitrotoluene (EXP) 22-Hydroxycholesterol (ISO) 3,3',5-triiodo-L-thyronine (EXP) 3H-1,2-dithiole-3-thione (EXP) 4,4'-sulfonyldiphenol (ISO) 5-aza-2'-deoxycytidine (ISO) 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (EXP) 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime (ISO) 6-propyl-2-thiouracil (EXP) 8-Br-cAMP (ISO) 9-cis-retinoic acid (EXP) acetamide (EXP) acetylsalicylic acid (EXP) acrolein (ISO) aflatoxin B1 (ISO) all-trans-retinoic acid (ISO) alpha-pinene (ISO) aluminium atom (ISO) aluminium(0) (ISO) amiodarone (EXP) ammonium chloride (EXP) antimony(0) (ISO) Archazolid B (ISO) aristolochic acid A (ISO) arsane (ISO) arsenic atom (ISO) arsenite(3-) (ISO) avobenzone (ISO) Azaspiracid (ISO) azoxystrobin (ISO) benzbromarone (EXP) benzene (ISO) benzo[a]pyrene (ISO) beta-lapachone (ISO) beta-naphthoflavone (ISO) bexarotene (EXP) bis(2-ethylhexyl) phthalate (ISO) bisphenol A (EXP,ISO) bromobenzene (EXP) butan-1-ol (ISO) caffeine (EXP,ISO) capsaicin (ISO) captan (ISO) carbamazepine (ISO) carbon nanotube (ISO) chloropicrin (ISO) chlorpyrifos (ISO) cholesterol (ISO) chromium(6+) (ISO) ciguatoxin CTX1B (ISO) cisplatin (ISO) clobetasol (ISO) clofibrate (EXP) cocaine (ISO) copper atom (EXP,ISO) copper(0) (EXP,ISO) copper(II) chloride (ISO) copper(II) sulfate (ISO) coumestrol (ISO) curcumin (EXP) cyclosporin A (ISO) cyproconazole (ISO) deoxynivalenol (ISO) dexamethasone (EXP) dibutyl phthalate (EXP) dichloromethane (ISO) difenoconazole (EXP) dimethylarsinic acid (ISO) dinophysistoxin 1 (ISO) dioxygen (ISO) dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO) diuron (ISO) dorsomorphin (ISO) doxorubicin (ISO) elemental selenium (ISO) endosulfan (EXP) Enterolactone (ISO) entinostat (ISO) epoxiconazole (ISO) ethanol (ISO) ethyl methanesulfonate (ISO) etoposide (ISO) farnesol (ISO) fenarimol (EXP) fenofibrate (ISO) flavonoids (ISO) fluoranthene (ISO) fluoxetine (ISO) flusilazole (EXP,ISO) fluvastatin (ISO) folic acid (ISO) folpet (ISO) formaldehyde (ISO) fumonisin B1 (ISO) Ganoderic acid A (ISO) gentamycin (EXP) GW 4064 (ISO) hexaconazole (ISO) hydrogen peroxide (ISO) isoflavones (ISO) isotretinoin (ISO) ivermectin (ISO) ketamine (EXP) ketoconazole (EXP) L-ethionine (EXP) lead nitrate (EXP) lead(0) (ISO) leflunomide (ISO) lovastatin (ISO) maneb (ISO) methidathion (ISO) methyl methanesulfonate (ISO) methylarsonic acid (ISO) methylmercury chloride (ISO) miconazole (ISO) mitomycin C (ISO) mitoxantrone (ISO) N-ethyl-N-nitrosourea (EXP) N-methyl-4-phenylpyridinium (ISO) N-nitrosodiethylamine (EXP) N-nitrosodimethylamine (ISO) okadaic acid (ISO) oleic acid (ISO) omeprazole (EXP) ozone (EXP,ISO) p-chloromercuribenzoic acid (ISO) paclitaxel (ISO) paracetamol (EXP,ISO) paraquat (ISO) perfluorobutanesulfonic acid (EXP) perfluorobutyric acid (EXP) perfluorododecanoic acid (EXP) perfluorohexanesulfonic acid (EXP,ISO) perfluorohexanoic acid (EXP) perfluorononanoic acid (EXP,ISO) perfluorooctane-1-sulfonic acid (EXP,ISO) perfluorooctanoic acid (EXP,ISO) perfluoroundecanoic acid (EXP) phencyclidine (ISO) phenobarbital (EXP,ISO) phenylmercury acetate (ISO) phenylpropanolamine (ISO) phosgene (ISO) picoxystrobin (ISO) pirinixic acid (EXP,ISO) piroxicam (ISO) potassium dichromate (ISO) pravastatin (ISO) pregnenolone 16alpha-carbonitrile (ISO) progesterone (ISO) propiconazole (EXP) quercetin (ISO) quercetin 3-O-beta-D-glucofuranoside (ISO) quercetin 3-O-beta-D-glucopyranoside (ISO) resveratrol (ISO) rotenone (EXP,ISO) SB 431542 (ISO) selenium atom (ISO) senecionine (ISO) simvastatin (EXP,ISO) sodium arsenate (ISO) sodium arsenite (ISO) Soman (EXP) sunitinib (ISO) tetrachloromethane (EXP,ISO) tetracycline (ISO) thapsigargin (ISO) Theaflavin 3,3'-digallate (ISO) thioacetamide (EXP) titanium dioxide (ISO) topotecan (ISO) triadimefon (ISO) trichloroethene (EXP) trimellitic anhydride (ISO) triphenyl phosphate (EXP,ISO) Triptolide (EXP) tunicamycin (ISO) undecane (EXP) valproic acid (ISO) vincristine (ISO) vorinostat (ISO) Yessotoxin (ISO) zoledronic acid (EXP,ISO)
1.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
3.
KEGG: Kyoto Encyclopedia of Genes and Genomes
KEGG
4.
Molecular cloning, expression, and characterization of the cDNA for the rat hepatic squalene synthase.
McKenzie TL, etal., J Biol Chem 1992 Oct 25;267(30):21368-74.
5.
Lanosterol synthase mutations cause cholesterol deficiency-associated cataracts in the Shumiya cataract rat.
Mori M, etal., J Clin Invest. 2006 Feb;116(2):395-404. Epub 2006 Jan 26.
6.
Electronic Transfer of LocusLink and RefSeq Data
NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.
KEGG Annotation Import Pipeline
Pipeline to import KEGG annotations from KEGG into RGD
8.
SMPDB Annotation Import Pipeline
Pipeline to import SMPDB annotations from SMPDB into RGD
9.
GOA pipeline
RGD automated data pipeline
10.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
11.
Solubilization, purification, and characterization of a truncated form of rat hepatic squalene synthetase.
Shechter I, etal., J Biol Chem 1992 Apr 25;267(12):8628-35.
12.
Subcellular localization of squalene synthase in rat hepatic cells. Biochemical and immunochemical evidence.
Stamellos KD, etal., J Biol Chem. 1993 Jun 15;268(17):12825-36.
13.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
14.
Tentative Sequence Identification Numbers
Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15.
Defects of cholesterol biosynthesis.
Waterham HR FEBS Lett. 2006 Oct 9;580(23):5442-9. Epub 2006 Jul 20.
Fdft1 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 15 41,588,114 - 41,616,168 (-) NCBI GRCr8 mRatBN7.2 15 37,412,143 - 37,440,198 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 15 37,412,146 - 37,440,287 (-) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 15 39,264,820 - 39,292,948 (-) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 15 40,415,629 - 40,443,757 (-) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 15 38,872,774 - 38,900,828 (-) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 15 46,339,248 - 46,367,302 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 46,339,249 - 46,367,302 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 15 50,104,042 - 50,132,096 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 42,425,336 - 42,453,390 (-) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 15 42,442,550 - 42,469,109 (-) NCBI Celera 15 37,096,417 - 37,124,524 (-) NCBI Celera Cytogenetic Map 15 p12 NCBI
FDFT1 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 8 11,795,582 - 11,839,298 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 8 11,795,573 - 11,839,395 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 8 11,653,091 - 11,696,807 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 8 11,697,599 - 11,734,227 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 8 11,697,663 - 11,734,215 NCBI Celera 8 10,789,513 - 10,826,122 (+) NCBI Celera Cytogenetic Map 8 p23.1 NCBI HuRef 8 10,591,147 - 10,627,774 (+) NCBI HuRef CHM1_1 8 11,725,653 - 11,762,299 (+) NCBI CHM1_1 T2T-CHM13v2.0 8 7,901,010 - 7,944,714 (-) NCBI T2T-CHM13v2.0
Fdft1 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 14 63,382,599 - 63,419,136 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 14 63,382,599 - 63,417,027 (-) Ensembl GRCm39 Ensembl GRCm38 14 63,145,150 - 63,181,687 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 14 63,145,150 - 63,179,578 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 14 63,763,987 - 63,796,630 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 14 62,099,260 - 62,131,903 (-) NCBI MGSCv36 mm8 Celera 14 60,907,922 - 60,941,524 (-) NCBI Celera Cytogenetic Map 14 D1 NCBI cM Map 14 33.24 NCBI
Fdft1 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955403 53,067,637 - 53,081,499 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955403 53,068,011 - 53,081,499 (+) NCBI ChiLan1.0 ChiLan1.0
FDFT1 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 7 28,270,343 - 28,306,745 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 8 4,296,571 - 4,332,974 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 8 7,363,250 - 7,399,863 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3
FDFT1 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 25 26,060,031 - 26,093,515 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 25 26,060,386 - 26,093,582 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 25 26,717,027 - 26,750,517 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 25 26,215,096 - 26,248,206 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 25 26,212,580 - 26,248,141 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 25 26,160,696 - 26,194,180 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 25 26,064,844 - 26,097,943 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 25 26,216,048 - 26,249,367 (-) NCBI UU_Cfam_GSD_1.0
Fdft1
FDFT1 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 14 14,967,074 - 15,016,227 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 14 14,976,259 - 15,010,701 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 14 16,164,964 - 16,199,406 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
FDFT1 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 8 7,272,580 - 7,306,859 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 8 7,271,509 - 7,306,760 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666052 35,129,389 - 35,164,015 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Fdft1
.
Predicted Target Of
Count of predictions: 454 Count of miRNA genes: 244 Interacting mature miRNAs: 298 Transcripts: ENSRNOT00000032089 Prediction methods: Microtar, Miranda, Targetscan Result types: miRGate_prediction
1331729 Rf42 Renal function QTL 42 3.071 kidney blood vessel physiology trait (VT:0100012) absolute change in renal blood flow rate (CMO:0001168) 15 17362897 73690657 Rat 1641887 Alcrsp14 Alcohol response QTL 14 response to alcohol trait (VT:0010489) brain neurotensin receptor 1 density (CMO:0002068) 15 1 42356671 Rat 10755503 Bp391 Blood pressure QTL 391 2.37 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 15 20248600 37896129 Rat 1582227 Gluco30 Glucose level QTL 30 3.6 0.0003 blood glucose amount (VT:0000188) absolute change in blood glucose level area under curve (CMO:0002034) 15 28030665 82262678 Rat 1582228 Epfw3 Epididymal fat weight QTL 3 4.1 0.0002 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 15 28030665 82262678 Rat 1578646 Bmd18 Bone mineral density QTL 18 5.2 femur mineral mass (VT:0010011) trabecular volumetric bone mineral density (CMO:0001729) 15 22806240 98288169 Rat 1578647 Bmd17 Bone mineral density QTL 17 4 femur mineral mass (VT:0010011) total volumetric bone mineral density (CMO:0001728) 15 22806240 98288169 Rat 10401805 Kidm51 Kidney mass QTL 51 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 15 306329 45306329 Rat 2293686 Bmd36 Bone mineral density QTL 36 7.4 0.0001 femur strength trait (VT:0010010) femoral neck ultimate force (CMO:0001703) 15 33611058 71477291 Rat 2317750 Glom26 Glomerulus QTL 26 4.3 urine protein amount (VT:0005160) urine protein level (CMO:0000591) 15 12496141 65205939 Rat 2298549 Neuinf12 Neuroinflammation QTL 12 3.5 nervous system integrity trait (VT:0010566) spinal cord beta-2 microglobulin mRNA level (CMO:0002125) 15 1 55302115 Rat 2293691 Bmd37 Bone mineral density QTL 37 6.6 0.0001 femur strength trait (VT:0010010) femur total energy absorbed before break (CMO:0001677) 15 33611058 71477291 Rat 2293688 Bss29 Bone structure and strength QTL 29 5.31 0.0001 femur morphology trait (VT:0000559) femur midshaft cortical cross-sectional area (CMO:0001663) 15 11111142 56111142 Rat 1582214 Stl21 Serum triglyceride level QTL 21 3.1 0.022 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 15 28030665 82262678 Rat 631273 Lecl2 Lens clarity QTL 2 0.001 lens clarity trait (VT:0001304) age of onset/diagnosis of cataract (CMO:0001584) 15 10596089 55596089 Rat 2300167 Bmd63 Bone mineral density QTL 63 5.9 0.0001 femur mineral mass (VT:0010011) volumetric bone mineral density (CMO:0001553) 15 11111142 56111142 Rat 731170 Pur3 Proteinuria QTL 3 2.3 0.0005 urine protein amount (VT:0005160) urine protein excretion rate (CMO:0000759) 15 1 41686771 Rat 738017 Hcas7 Hepatocarcinoma susceptibility QTL 7 2.91 liver integrity trait (VT:0010547) liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464) 15 2266368 46921453 Rat 152025253 Hrtrt24 Heart rate QTL 24 3.82 heart pumping trait (VT:2000009) 15 27885774 86257085 Rat 10054130 Srcrt8 Stress Responsive Cort QTL 8 2.18 0.0085 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 15 22117933 67117933 Rat 2300173 Bmd62 Bone mineral density QTL 62 12.8 0.0001 lumbar vertebra mineral mass (VT:0010511) volumetric bone mineral density (CMO:0001553) 15 11111142 56111142 Rat 2324620 Coatc3 Coat color QTL 3 coat/hair pigmentation trait (VT:0010463) pigmented coat/hair area to total coat/hair area ratio (CMO:0001810) 15 19856566 46187442 Rat 61424 Scl1 Serum cholesterol level QTL 1 7.7 0.001 blood cholesterol amount (VT:0000180) serum total cholesterol level (CMO:0000363) 15 16725528 80672115 Rat 1582251 Gluco24 Glucose level QTL 24 3.2 0.0008 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 15 5530756 50530756 Rat 1598828 Glom14 Glomerulus QTL 14 2.5 kidney glomerulus morphology trait (VT:0005325) index of glomerular damage (CMO:0001135) 15 34054139 79054139 Rat 1582242 Gluco28 Glucose level QTL 28 3.3 0.0008 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 15 28030665 82262678 Rat 1578660 Bss19 Bone structure and strength QTL 19 4.3 femur morphology trait (VT:0000559) bone trabecular cross-sectional area (CMO:0002311) 15 22806240 98288169 Rat 1582244 Bw79 Body weight QTL 79 4 0.0002 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 15 28030665 82262678 Rat
RH128506
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 15 37,412,224 - 37,412,411 (+) MAPPER mRatBN7.2 Rnor_6.0 15 46,339,330 - 46,339,516 NCBI Rnor6.0 Rnor_5.0 15 50,104,124 - 50,104,310 UniSTS Rnor5.0 RGSC_v3.4 15 42,425,418 - 42,425,604 UniSTS RGSC3.4 Celera 15 37,096,499 - 37,096,685 UniSTS RH 3.4 Map 15 269.5 UniSTS Cytogenetic Map 15 p12 UniSTS
RH133832
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 15 37,413,761 - 37,413,977 (+) MAPPER mRatBN7.2 Rnor_6.0 15 46,340,867 - 46,341,082 NCBI Rnor6.0 Rnor_5.0 15 50,105,661 - 50,105,876 UniSTS Rnor5.0 RGSC_v3.4 15 42,426,955 - 42,427,170 UniSTS RGSC3.4 Celera 15 37,098,036 - 37,098,251 UniSTS Cytogenetic Map 15 p12 UniSTS
BE105722
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 15 37,411,874 - 37,412,043 (+) MAPPER mRatBN7.2 Rnor_6.0 15 46,338,980 - 46,339,148 NCBI Rnor6.0 Rnor_5.0 15 50,103,774 - 50,103,942 UniSTS Rnor5.0 RGSC_v3.4 15 42,425,068 - 42,425,236 UniSTS RGSC3.4 Celera 15 37,096,149 - 37,096,317 UniSTS RH 3.4 Map 15 272.2 UniSTS Cytogenetic Map 15 p12 UniSTS
AI176781
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 15 37,411,797 - 37,411,997 (+) MAPPER mRatBN7.2 Rnor_6.0 15 46,338,903 - 46,339,102 NCBI Rnor6.0 Rnor_5.0 15 50,103,697 - 50,103,896 UniSTS Rnor5.0 RGSC_v3.4 15 42,424,991 - 42,425,190 UniSTS RGSC3.4 Celera 15 37,096,072 - 37,096,271 UniSTS RH 3.4 Map 15 270.3 UniSTS Cytogenetic Map 15 p12 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
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Ensembl Acc Id:
ENSRNOT00000032089 ⟹ ENSRNOP00000029808
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 15 37,412,155 - 37,440,287 (-) Ensembl Rnor_6.0 Ensembl 15 46,339,249 - 46,367,302 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000117968 ⟹ ENSRNOP00000086658
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 15 37,412,146 - 37,440,194 (-) Ensembl
RefSeq Acc Id:
NM_019238 ⟹ NP_062111
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 15 41,588,114 - 41,616,168 (-) NCBI mRatBN7.2 15 37,412,143 - 37,440,198 (-) NCBI Rnor_6.0 15 46,339,248 - 46,367,302 (-) NCBI Rnor_5.0 15 50,104,042 - 50,132,096 (-) NCBI RGSC_v3.4 15 42,425,336 - 42,453,390 (-) RGD Celera 15 37,096,417 - 37,124,524 (-) RGD
Sequence:
GCCTACCGCCGGCATCTAAACACAGGTGGGAGTGGGAGATCCCGACAGGTGAGCCCCGCGCCCCGCAGCCACAAGGATGGAGTTCGTGAAGTGTCTAGGCCACCCGGAGGAGTTCTACAACCTGCTGC
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RefSeq Acc Id:
NP_062111 ⟸ NM_019238
- UniProtKB:
Q02769 (UniProtKB/Swiss-Prot), A6K6F7 (UniProtKB/TrEMBL), A0A8I6GF68 (UniProtKB/TrEMBL)
- Sequence:
MEFVKCLGHPEEFYNLLRFRMGGRRNFIPKMDRNSLSNSLKTCYKYLDQTSRSFAAVIQALDGDIRHAVCVFYLILRAMDTVEDDMAISVEKKIPLLRNFHTFLYEPEWRFTESKEKHRVVLEDFPTI
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Ensembl Acc Id:
ENSRNOP00000029808 ⟸ ENSRNOT00000032089
Ensembl Acc Id:
ENSRNOP00000086658 ⟸ ENSRNOT00000117968
RGD ID: 13699776 Promoter ID: EPDNEW_R10298 Type: initiation region Name: Fdft1_1 Description: farnesyl diphosphate farnesyl transferase 1 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/ ) Experiment Methods: Single-end sequencing. Position: Rat Assembly Chr Position (strand) Source Rnor_6.0 15 46,367,315 - 46,367,375 EPDNEW
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2002-06-10
Fdft1
farnesyl diphosphate farnesyl transferase 1
Name updated
70584 APPROVED
