Rnase4 (ribonuclease A family member 4) - Rat Genome Database

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Gene: Rnase4 (ribonuclease A family member 4) Rattus norvegicus
Analyze
Symbol: Rnase4
Name: ribonuclease A family member 4
RGD ID: 61823
Description: Predicted to enable RNA nuclease activity. Predicted to be involved in antibacterial humoral response and defense response to Gram-positive bacterium. Predicted to act upstream of or within cellular response to starvation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human RNASE4 (ribonuclease A family member 4); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Rab1; ribonuclease 4; ribonuclease A b1; ribonuclease, RNase A family 4; RL3; RNase 4
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,786,287 - 26,803,634 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1526,786,079 - 26,803,639 (+)EnsemblGRCr8
mRatBN7.21524,312,765 - 24,330,112 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,312,464 - 24,330,117 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1527,083,931 - 27,101,281 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,043,091 - 28,060,440 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,292,490 - 26,309,841 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,018,040 - 28,035,395 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01531,850,396 - 31,866,409 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41527,073,756 - 27,090,441 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1524,631,848 - 24,647,995 (+)NCBICelera
RGSC_v3.11527,089,455 - 27,106,139 (+)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphotericin B  (ISO)
Aroclor 1254  (EXP)
avobenzone  (ISO)
azathioprine  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (EXP)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
carnosic acid  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
choline  (EXP,ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dicrotophos  (ISO)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
diquat  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
folic acid  (EXP,ISO)
furan  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
GW 4064  (ISO)
hydroquinone  (ISO)
inulin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoprenaline  (ISO)
ketamine  (EXP)
ketoconazole  (EXP)
L-ethionine  (EXP)
L-methionine  (EXP,ISO)
lead diacetate  (ISO)
lead(II) chloride  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
omeprazole  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
S-nitrosoglutathione  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sulfadimethoxine  (EXP)
Tesaglitazar  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
9. Ribonucleases from rat and bovine liver: purification, specificity and structural characterization. Zhao W, etal., Biochim Biophys Acta 1998 Apr 23;1384(1):55-65.
Additional References at PubMed
PMID:3467790   PMID:15489334   PMID:23260145   PMID:23376485   PMID:24006456   PMID:24337645  


Genomics

Comparative Map Data
Rnase4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,786,287 - 26,803,634 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1526,786,079 - 26,803,639 (+)EnsemblGRCr8
mRatBN7.21524,312,765 - 24,330,112 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,312,464 - 24,330,117 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1527,083,931 - 27,101,281 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01528,043,091 - 28,060,440 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01526,292,490 - 26,309,841 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01528,018,040 - 28,035,395 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01531,850,396 - 31,866,409 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41527,073,756 - 27,090,441 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1524,631,848 - 24,647,995 (+)NCBICelera
RGSC_v3.11527,089,455 - 27,106,139 (+)NCBI
Cytogenetic Map15p14NCBI
RNASE4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,684,560 - 20,701,216 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,682,598 - 20,701,216 (+)Ensemblhg38GRCh38
GRCh371421,152,719 - 21,169,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,222,212 - 20,238,598 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341420,226,771 - 20,238,597NCBI
Celera141,013,244 - 1,029,632 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef141,273,295 - 1,289,678 (+)NCBIHuRef
CHM1_11421,154,392 - 21,170,774 (+)NCBICHM1_1
T2T-CHM13v2.01414,881,670 - 14,898,327 (+)NCBIT2T-CHM13v2.0
Rnase4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,328,534 - 51,343,608 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,328,534 - 51,343,608 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381451,091,077 - 51,106,151 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,091,077 - 51,106,151 (+)Ensemblmm10GRCm38
MGSCv371451,710,752 - 51,725,826 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361450,013,147 - 50,028,091 (+)NCBIMGSCv36mm8
MGSCv361442,955,672 - 42,970,033 (+)NCBIMGSCv36mm8
Celera1447,385,172 - 47,400,997 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.37NCBI
RNASE4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21522,182,660 - 22,200,165 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,397,673 - 21,416,652 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,548,729 - 1,564,819 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,605,890 - 19,621,987 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,620,758 - 19,621,201 (+)EnsemblpanPan2panpan1.1
RNASE4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,981,661 - 17,998,644 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,981,647 - 18,004,631 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1518,467,471 - 18,484,458 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01518,242,716 - 18,259,707 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1518,242,716 - 18,260,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,924,113 - 17,941,085 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,980,204 - 17,997,189 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01518,107,982 - 18,124,962 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rnase4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,124,933 - 32,133,608 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493688034,289 - 43,209 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493688041,940 - 42,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNASE4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,243,691 - 78,244,930 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1778,244,284 - 78,244,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RNASE4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,216,021 - 21,233,306 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2921,216,477 - 21,232,699 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605925,197,478 - 25,214,890 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnase4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11272,201,370 - 72,218,749 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rnase4
1268 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:84
Count of miRNA genes:67
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000041495
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat

Markers in Region
RH127443  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21524,329,729 - 24,329,913 (+)MAPPERmRatBN7.2
Rnor_6.01528,035,009 - 28,035,192NCBIRnor6.0
Rnor_5.01531,866,023 - 31,866,206UniSTSRnor5.0
RGSC_v3.41527,090,059 - 27,090,242UniSTSRGSC3.4
Celera1524,647,613 - 24,647,796UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
25 23 105 224 179 177 118 114 118 12 556 275 11 183 122 143 59 14 14

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_020082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG328957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041495   ⟹   ENSRNOP00000043003
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1526,786,110 - 26,803,636 (+)Ensembl
mRatBN7.2 Ensembl1524,312,464 - 24,330,117 (+)Ensembl
Rnor_6.0 Ensembl1528,018,040 - 28,035,389 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089631   ⟹   ENSRNOP00000073131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1526,786,079 - 26,803,639 (+)Ensembl
mRatBN7.2 Ensembl1524,312,557 - 24,330,117 (+)Ensembl
Rnor_6.0 Ensembl1528,028,521 - 28,035,389 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090272   ⟹   ENSRNOP00000069341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1528,023,018 - 28,034,590 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000142422   ⟹   ENSRNOP00000098851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1526,786,231 - 26,803,636 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000145218   ⟹   ENSRNOP00000101514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1526,786,227 - 26,803,636 (+)Ensembl
RefSeq Acc Id: NM_020082   ⟹   NP_064467
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,786,287 - 26,803,634 (+)NCBI
mRatBN7.21524,312,765 - 24,330,112 (+)NCBI
Rnor_6.01528,018,040 - 28,035,391 (+)NCBI
Rnor_5.01531,850,396 - 31,866,409 (+)NCBI
RGSC_v3.41527,073,756 - 27,090,441 (+)RGD
Celera1524,631,848 - 24,647,995 (+)RGD
Sequence:
RefSeq Acc Id: XM_063274591   ⟹   XP_063130661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,790,215 - 26,803,634 (+)NCBI
RefSeq Acc Id: XM_063274592   ⟹   XP_063130662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,796,265 - 26,803,634 (+)NCBI
RefSeq Acc Id: NP_064467   ⟸   NM_020082
- Peptide Label: precursor
- UniProtKB: O55004 (UniProtKB/Swiss-Prot),   W0UVG1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073131   ⟸   ENSRNOT00000089631
Ensembl Acc Id: ENSRNOP00000069341   ⟸   ENSRNOT00000090272
Ensembl Acc Id: ENSRNOP00000043003   ⟸   ENSRNOT00000041495
RefSeq Acc Id: XP_063130661   ⟸   XM_063274591
- Peptide Label: isoform X1
- UniProtKB: O55004 (UniProtKB/Swiss-Prot),   W0UVG1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130662   ⟸   XM_063274592
- Peptide Label: isoform X1
- UniProtKB: O55004 (UniProtKB/Swiss-Prot),   W0UVG1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101514   ⟸   ENSRNOT00000145218
Ensembl Acc Id: ENSRNOP00000098851   ⟸   ENSRNOT00000142422
Protein Domains
Ribonuclease A-domain

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O55004-F1-model_v2 AlphaFold O55004 1-147 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699629
Promoter ID:EPDNEW_R10151
Type:initiation region
Name:Rnase4_1
Description:ribonuclease A family member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10152  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01528,017,985 - 28,018,045EPDNEW
RGD ID:13699642
Promoter ID:EPDNEW_R10152
Type:multiple initiation site
Name:Rnase4_2
Description:ribonuclease A family member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10151  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01528,022,993 - 28,023,053EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61823 AgrOrtholog
BioCyc Gene G2FUF-14031 BioCyc
Ensembl Genes ENSRNOG00000025625 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000051860 Ensembl
Ensembl Transcript ENSRNOT00000041495 ENTREZGENE
  ENSRNOT00000041495.5 UniProtKB/Swiss-Prot
  ENSRNOT00000089631.2 UniProtKB/Swiss-Prot
  ENSRNOT00000145218 ENTREZGENE
Gene3D-CATH 3.10.130.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7103267 IMAGE-MGC_LOAD
  IMAGE:7372999 IMAGE-MGC_LOAD
InterPro RNaseA UniProtKB/Swiss-Prot
  RNaseA-like_dom_sf UniProtKB/Swiss-Prot
  RNaseA_AS UniProtKB/Swiss-Prot
  RNaseA_domain UniProtKB/Swiss-Prot
KEGG Report rno:56759 UniProtKB/Swiss-Prot
MGC_CLONE MGC:187485 IMAGE-MGC_LOAD
  MGC:91709 IMAGE-MGC_LOAD
NCBI Gene 56759 ENTREZGENE
PANTHER PTHR11437 UniProtKB/Swiss-Prot
  RIBONUCLEASE 4 UniProtKB/Swiss-Prot
Pfam RnaseA UniProtKB/Swiss-Prot
PhenoGen Rnase4 PhenoGen
PRINTS RIBONUCLEASE UniProtKB/Swiss-Prot
PROSITE RNASE_PANCREATIC UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000025625 RatGTEx
  ENSRNOG00000051860 RatGTEx
SMART RNAse_Pc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54076 UniProtKB/Swiss-Prot
TIGR TC233653
UniProt A6KED1_RAT UniProtKB/TrEMBL
  B2GUW7_RAT UniProtKB/TrEMBL
  O55004 ENTREZGENE, UniProtKB/Swiss-Prot
  W0UVG1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Rnase4  ribonuclease A family member 4  Rnase4  ribonuclease, RNase A family 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Rnase4  ribonuclease, RNase A family 4       Name updated 70584 APPROVED
2001-07-23 Rnase4  ribonuclease, RNase A family 4      Name withdrawn 67952 APPROVED
2001-07-23 Rnase4  ibonuclease, RNase A family 4      Name withdrawn 67952 WITHDRAWN

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver 61732