Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | autistic disorder | | ISO | TSPY1 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Autism | ClinVar | PMID:21681106 and PMID:30208311 | |
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Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | autistic disorder | | ISO | TSPY1 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Autism | ClinVar | PMID:21681106 and PMID:30208311 | |
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# | Reference Title | Reference Citation |
1. | Organization and expression of rat Tspy. | Dechend F, etal., Cytogenet Cell Genet 1998;83(3-4):270-4. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
4. | The rat Tspy is preferentially expressed in elongated spermatids and interacts with the core histones. | Kido T and Lau YF, Biochem Biophys Res Commun. 2006 Nov 10;350(1):56-67. Epub 2006 Sep 14. |
5. | The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors. | Li Y, etal., Hum Pathol. 2007 Oct;38(10):1470-81. Epub 2007 May 22. |
6. | Rodent Y chromosome TSPY gene is functional in rat and non-functional in mouse. | Mazeyrat S and Mitchell MJ, Hum Mol Genet 1998 Mar;7(3):557-62. |
7. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
9. | Detection of recurrent copy number loss at Yp11.2 involving TSPY gene cluster in prostate cancer using array-based comparative genomic hybridization. | Vijayakumar S, etal., Cancer Res. 2006 Apr 15;66(8):4055-64. |
10. | TSPY is a cancer testis antigen expressed in human hepatocellular carcinoma. | Yin YH, etal., Br J Cancer. 2005 Aug 22;93(4):458-63. |
Tspy1 (Rattus norvegicus - Norway rat) |
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TSPY1 (Homo sapiens - human) |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | |||||||||||||
Low | 1 | 12 | 4 | 9 | 4 | 1 | 1 | 3 | 4 | 11 | 4 | 1 | |
Below cutoff | 2 | 21 | 18 | 18 | 2 | 18 | 3 | 4 | 19 | 10 | 11 | 2 | 3 |
RefSeq Acc Id: | ENSRNOT00000077988 ⟹ ENSRNOP00000071386 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000083382 ⟹ ENSRNOP00000075045 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_022923 ⟹ NP_075212 | ||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008773672 ⟹ XP_008771894 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039100721 ⟹ XP_038956649 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XR_005498751 | ||||||||
Type: | NON-CODING | ||||||||
Position: |
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RefSeq Acc Id: | XP_008771894 ⟸ XM_008773672 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70602 (UniProtKB/Swiss-Prot), Q9R1M4 (UniProtKB/Swiss-Prot), Q9R1M3 (UniProtKB/Swiss-Prot), A0A8L2R474 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | NP_075212 ⟸ NM_022923 |
- UniProtKB: | Q9R1M3 (UniProtKB/Swiss-Prot), O70602 (UniProtKB/Swiss-Prot), Q9R1M4 (UniProtKB/Swiss-Prot), A0A8L2R474 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000071386 ⟸ ENSRNOT00000077988 |
RefSeq Acc Id: | ENSRNOP00000075045 ⟸ ENSRNOT00000083382 |
RefSeq Acc Id: | XP_038956649 ⟸ XM_039100721 |
- Peptide Label: | isoform X2 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q9R1M3-F1-model_v2 | AlphaFold | Q9R1M3 | 1-334 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:3912 | AgrOrtholog |
BioCyc Gene | G2FUF-425 | BioCyc |
Ensembl Genes | ENSRNOG00000054648 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
ENSRNOG00055000692 | UniProtKB/Swiss-Prot | |
ENSRNOG00060008676 | UniProtKB/Swiss-Prot | |
ENSRNOG00065000210 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000077988.2 | UniProtKB/TrEMBL |
ENSRNOT00000083382 | ENTREZGENE | |
ENSRNOT00000083382.3 | UniProtKB/Swiss-Prot | |
ENSRNOT00000116666.1 | UniProtKB/Swiss-Prot | |
ENSRNOT00055001182 | UniProtKB/Swiss-Prot | |
ENSRNOT00060014513 | UniProtKB/Swiss-Prot | |
ENSRNOT00065000363 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 1.20.5.1500 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Nucleosome assembly protein | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
InterPro | NAP-like_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
NAP_family | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:25223 | UniProtKB/Swiss-Prot |
NCBI Gene | 25223 | ENTREZGENE |
PANTHER | PTHR11875 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
TESTIS-SPECIFIC Y-ENCODED PROTEIN 1-RELATED | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | NAP | UniProtKB/Swiss-Prot |
PhenoGen | Tspy1 | PhenoGen |
RatGTEx | ENSRNOG00000054648 | RatGTEx |
ENSRNOG00055000692 | RatGTEx | |
ENSRNOG00060008676 | RatGTEx | |
ENSRNOG00065000210 | RatGTEx | |
Superfamily-SCOP | SSF143113 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
UniProt | A0A8L2R474 | ENTREZGENE, UniProtKB/TrEMBL |
O70602 | ENTREZGENE | |
Q9R1M3 | ENTREZGENE | |
Q9R1M4 | ENTREZGENE | |
TSPY1_RAT | UniProtKB/Swiss-Prot | |
UniProt Secondary | O70602 | UniProtKB/Swiss-Prot |
Q9R1M4 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-02-15 | Tspy1 | testis specific protein, Y-linked 1 | Tspy | testis specific protein, Y-linked | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2003-04-09 | Tspy | testis specific protein, Y-linked | Testis specific protein on Y | Name updated | 629478 | APPROVED | |
2002-06-10 | Tspy | Testis specific protein on Y | Symbol and Name status set to approved | 70586 | APPROVED |
Note Type | Note | Reference |
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gene_homology | 47% amino acid identity to human homolog | 634385 |