Tmod1 (tropomodulin 1) - Rat Genome Database

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Pathways
Gene: Tmod1 (tropomodulin 1) Rattus norvegicus
Analyze
Symbol: Tmod1
Name: tropomodulin 1
RGD ID: 3874
Description: Enables tropomyosin binding activity. Predicted to be involved in actin cytoskeleton organization; lens fiber cell development; and muscle contraction. Predicted to act upstream of or within adult locomotory behavior. Predicted to be located in cytoskeleton; membrane; and sarcomere. Predicted to be part of COP9 signalosome. Predicted to be active in striated muscle thin filament. Orthologous to human TMOD1 (tropomodulin 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E-Tmod; E-Tropomodulin; erythrocyte tropomodulin; Tmod; tropomodulin-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,112,062 - 65,189,563 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl565,134,132 - 65,189,561 (+)EnsemblGRCr8
mRatBN7.2560,316,445 - 60,393,957 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,338,512 - 60,393,956 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx562,288,970 - 62,366,361 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,108,477 - 64,185,864 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,077,726 - 64,155,120 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0561,635,244 - 61,712,052 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,657,507 - 61,712,051 (+)Ensemblrn6Rnor6.0
Rnor_5.0566,151,206 - 66,228,500 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4562,578,142 - 62,668,760 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera558,878,456 - 58,954,722 (+)NCBICelera
RGSC_v3.1562,578,320 - 62,668,938 (+)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrylamide  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
astemizole  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethanol  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glucose  (ISO)
graphite  (EXP)
lead nitrate  (EXP)
methapyrilene  (ISO)
methimazole  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel sulfate  (ISO)
nitrates  (ISO)
nitrofen  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
progesterone  (EXP,ISO)
raloxifene  (ISO)
S-nitrosoglutathione  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
sulforaphane  (ISO)
tamoxifen  (ISO)
Tesaglitazar  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
tremolite asbestos  (ISO)
triadimefon  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
actin filament  (IEA,ISO,ISS)
COP9 signalosome  (IEA,ISO)
cortical cytoskeleton  (IEA,ISO)
cytoskeleton  (IBA,IEA)
membrane  (IEA,ISO)
myofibril  (IBA,IEA,ISO,ISS)
sarcomere  (IEA,ISO,ISS)
striated muscle thin filament  (IBA,IEA,ISO)

Molecular Function
actin binding  (IEA,ISO,ISS)
tropomyosin binding  (IBA,IDA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Cytoplasmic nuclear transfer of the actin-capping protein tropomodulin. Kong KY and Kedes L, J Biol Chem. 2004 Jul 16;279(29):30856-64. Epub 2004 Apr 29.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
9. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
10. N-tropomodulin: a novel isoform of tropomodulin identified as the major binding protein to brain tropomyosin. Watakabe A, etal., J Cell Sci 1996 Sep;109 ( Pt 9)(2):2299-310.
Additional References at PubMed
PMID:14657235   PMID:14741341   PMID:18723693   PMID:18850735   PMID:20368620   PMID:20685966   PMID:21078668   PMID:23144950   PMID:24840128   PMID:25250574   PMID:26370058   PMID:27126680  
PMID:30301754   PMID:35352799  


Genomics

Comparative Map Data
Tmod1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,112,062 - 65,189,563 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl565,134,132 - 65,189,561 (+)EnsemblGRCr8
mRatBN7.2560,316,445 - 60,393,957 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,338,512 - 60,393,956 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx562,288,970 - 62,366,361 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,108,477 - 64,185,864 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,077,726 - 64,155,120 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0561,635,244 - 61,712,052 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl561,657,507 - 61,712,051 (+)Ensemblrn6Rnor6.0
Rnor_5.0566,151,206 - 66,228,500 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4562,578,142 - 62,668,760 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera558,878,456 - 58,954,722 (+)NCBICelera
RGSC_v3.1562,578,320 - 62,668,938 (+)NCBI
Cytogenetic Map5q22NCBI
TMOD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38997,501,180 - 97,601,743 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl997,501,180 - 97,601,743 (+)Ensemblhg38GRCh38
GRCh379100,263,462 - 100,364,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36999,326,258 - 99,403,351 (+)NCBIBuild 36Build 36hg18NCBI36
Celera970,777,697 - 70,878,281 (+)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef969,864,624 - 69,965,202 (+)NCBIHuRef
CHM1_19100,409,900 - 100,510,457 (+)NCBICHM1_1
T2T-CHM13v2.09109,673,130 - 109,773,684 (+)NCBIT2T-CHM13v2.0
Tmod1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39446,038,940 - 46,116,032 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl446,038,935 - 46,116,032 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38446,038,940 - 46,116,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl446,038,935 - 46,116,032 (+)Ensemblmm10GRCm38
MGSCv37446,052,094 - 46,128,904 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36446,082,066 - 46,135,896 (+)NCBIMGSCv36mm8
Celera446,061,367 - 46,138,280 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.49NCBI
Tmod1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541927,841,424 - 27,915,540 (-)Ensembl
ChiLan1.0NW_00495541927,841,424 - 27,915,540 (-)NCBIChiLan1.0ChiLan1.0
TMOD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21141,856,087 - 41,956,106 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1941,858,466 - 41,958,468 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0968,592,195 - 68,692,001 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1996,714,237 - 96,813,936 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl996,714,237 - 96,813,936 (+)EnsemblpanPan2panpan1.1
TMOD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11154,853,205 - 54,914,236 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1154,853,204 - 54,912,773 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1153,267,257 - 53,348,437 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01155,945,577 - 56,026,805 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1155,945,563 - 56,026,799 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11154,441,999 - 54,523,177 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01154,471,825 - 54,553,034 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,168,518 - 55,249,717 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tmod1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947169,778,850 - 169,856,410 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,326,400 - 6,403,057 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365246,347,089 - 6,403,996 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMOD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,396,097 - 239,467,758 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11239,375,150 - 239,468,387 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21267,547,207 - 267,646,850 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMOD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11241,808,594 - 41,899,713 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1241,811,036 - 41,877,357 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603838,861,593 - 38,953,232 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmod1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248253,228,305 - 3,299,799 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248253,229,095 - 3,299,709 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Tmod1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11399,167 - 470,713 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tmod1
735 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:424
Count of miRNA genes:223
Interacting mature miRNAs:285
Transcripts:ENSRNOT00000013228
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)565089051103648916Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)56458901693503770Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)56458901691762830Rat

Markers in Region
D5Mco30  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8565,129,594 - 65,129,843 (+)Marker Load Pipeline
mRatBN7.2560,333,977 - 60,334,226 (+)MAPPERmRatBN7.2
Rnor_6.0561,652,973 - 61,653,221NCBIRnor6.0
Rnor_5.0566,168,872 - 66,169,120UniSTSRnor5.0
RGSC_v3.4562,594,555 - 62,594,803UniSTSRGSC3.4
RGSC_v3.4562,594,554 - 62,594,802RGDRGSC3.4
Celera558,895,847 - 58,896,095UniSTS
RGSC_v3.1562,594,733 - 62,594,981RGD
Cytogenetic Map5q22UniSTS
BE102142  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,338,513 - 60,338,671 (+)MAPPERmRatBN7.2
Rnor_6.0561,657,509 - 61,657,666NCBIRnor6.0
Rnor_5.0566,173,408 - 66,173,565UniSTSRnor5.0
RGSC_v3.4562,599,091 - 62,599,248UniSTSRGSC3.4
Celera558,900,383 - 58,900,540UniSTS
RH 3.4 Map5379.7UniSTS
Cytogenetic Map5q22UniSTS
RH129174  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,393,009 - 60,393,229 (+)MAPPERmRatBN7.2
Rnor_6.0561,711,105 - 61,711,324NCBIRnor6.0
Rnor_5.0566,227,553 - 66,227,772UniSTSRnor5.0
RGSC_v3.4562,667,813 - 62,668,032UniSTSRGSC3.4
Celera558,953,775 - 58,953,994UniSTS
Cytogenetic Map5q22UniSTS
BE101076  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,338,525 - 60,338,671 (+)MAPPERmRatBN7.2
Rnor_6.0561,657,521 - 61,657,666NCBIRnor6.0
Rnor_5.0566,173,420 - 66,173,565UniSTSRnor5.0
RGSC_v3.4562,599,103 - 62,599,248UniSTSRGSC3.4
Celera558,900,395 - 58,900,540UniSTS
RH 3.4 Map5376.2UniSTS
Cytogenetic Map5q22UniSTS
AU048374  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,371,967 - 60,372,125 (+)MAPPERmRatBN7.2
Rnor_6.0561,690,957 - 61,691,114NCBIRnor6.0
Rnor_5.0566,207,085 - 66,207,242UniSTSRnor5.0
RGSC_v3.4562,632,540 - 62,632,697UniSTSRGSC3.4
Celera558,933,724 - 58,933,881UniSTS
Cytogenetic Map5q22UniSTS
BF391929  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8565,160,266 - 65,160,448 (+)Marker Load Pipeline
mRatBN7.2560,364,653 - 60,364,834 (+)MAPPERmRatBN7.2
Rnor_6.0561,683,645 - 61,683,825NCBIRnor6.0
Rnor_5.0566,199,773 - 66,199,953UniSTSRnor5.0
RGSC_v3.4562,625,228 - 62,625,408UniSTSRGSC3.4
Celera558,926,412 - 58,926,592UniSTS
RH 3.4 Map5717.0UniSTS
Cytogenetic Map5q22UniSTS
BM383810  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,378,356 - 60,378,561 (+)MAPPERmRatBN7.2
Rnor_6.0561,697,344 - 61,697,548NCBIRnor6.0
Rnor_5.0566,213,472 - 66,213,676UniSTSRnor5.0
RGSC_v3.4562,638,927 - 62,639,131UniSTSRGSC3.4
Celera558,940,111 - 58,940,315UniSTS
RH 3.4 Map5392.3UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 68 175 91 90 59 108 59 6 384 209 12 161 92 99 31 22 22

Sequence


Ensembl Acc Id: ENSRNOT00000013228   ⟹   ENSRNOP00000013228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl565,134,132 - 65,189,558 (+)Ensembl
mRatBN7.2 Ensembl560,338,512 - 60,393,956 (+)Ensembl
Rnor_6.0 Ensembl561,657,507 - 61,712,051 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109364   ⟹   ENSRNOP00000076573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl565,134,132 - 65,189,561 (+)Ensembl
mRatBN7.2 Ensembl560,338,512 - 60,387,529 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113823   ⟹   ENSRNOP00000077344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl565,138,291 - 65,189,561 (+)Ensembl
mRatBN7.2 Ensembl560,342,669 - 60,393,956 (+)Ensembl
RefSeq Acc Id: NM_013044   ⟹   NP_037176
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,112,062 - 65,189,563 (+)NCBI
mRatBN7.2560,316,445 - 60,393,957 (+)NCBI
Rnor_6.0561,635,611 - 61,712,052 (+)NCBI
Rnor_5.0566,151,206 - 66,228,500 (+)NCBI
RGSC_v3.4562,578,142 - 62,668,760 (+)RGD
Celera558,878,456 - 58,954,722 (+)RGD
Sequence:
RefSeq Acc Id: XM_039109314   ⟹   XP_038965242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,135,090 - 65,188,334 (+)NCBI
mRatBN7.2560,339,470 - 60,393,953 (+)NCBI
RefSeq Acc Id: XM_039109315   ⟹   XP_038965243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,135,109 - 65,188,334 (+)NCBI
mRatBN7.2560,339,491 - 60,393,953 (+)NCBI
RefSeq Acc Id: XM_063287195   ⟹   XP_063143265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,134,150 - 65,188,334 (+)NCBI
RefSeq Acc Id: NP_037176   ⟸   NM_013044
- UniProtKB: P70567 (UniProtKB/Swiss-Prot),   Q6IMZ5 (UniProtKB/TrEMBL),   A6IJA9 (UniProtKB/TrEMBL),   F7ELP2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013228   ⟸   ENSRNOT00000013228
RefSeq Acc Id: XP_038965242   ⟸   XM_039109314
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038965243   ⟸   XM_039109315
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000077344   ⟸   ENSRNOT00000113823
Ensembl Acc Id: ENSRNOP00000076573   ⟸   ENSRNOT00000109364
RefSeq Acc Id: XP_063143265   ⟸   XM_063287195
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70567-F1-model_v2 AlphaFold P70567 1-359 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3874 AgrOrtholog
BioCyc Gene G2FUF-41417 BioCyc
Ensembl Genes ENSRNOG00000009761 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013228 ENTREZGENE
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7105834 IMAGE-MGC_LOAD
InterPro LRR_dom_sf UniProtKB/Swiss-Prot
  TMOD UniProtKB/Swiss-Prot
MGC_CLONE MGC:91767 IMAGE-MGC_LOAD
NCBI Gene 25566 ENTREZGENE
PANTHER PTHR10901 UniProtKB/Swiss-Prot
  PTHR10901:SF8 UniProtKB/Swiss-Prot
Pfam Tropomodulin UniProtKB/Swiss-Prot
PhenoGen Tmod1 PhenoGen
RatGTEx ENSRNOG00000009761 RatGTEx
Superfamily-SCOP RNI-like UniProtKB/Swiss-Prot
TIGR TC228630
UniProt A0A8I5YBE0_RAT UniProtKB/TrEMBL
  A0A8I5ZKA1_RAT UniProtKB/TrEMBL
  A6IJA9 ENTREZGENE, UniProtKB/TrEMBL
  F7ELP2 ENTREZGENE, UniProtKB/TrEMBL
  P70567 ENTREZGENE
  Q6IMZ5 ENTREZGENE
  TMOD1_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2003-04-09 Tmod1  tropomodulin 1  Tmod  E-Tropomodulin  Symbol and Name updated 629477 APPROVED
2002-06-10 Tmod  E-Tropomodulin      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mainly expressed in neurons of the brain 61770