Syn3 (synapsin III) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Syn3 (synapsin III) Rattus norvegicus
Analyze
Symbol: Syn3
Name: synapsin III
RGD ID: 3799
Description: Enables ATP binding activity. Predicted to be involved in neurotransmitter secretion and synaptic vesicle clustering. Located in synaptic vesicle. Is extrinsic component of synaptic vesicle membrane. Orthologous to human SYN3 (synapsin III); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100910134; synapsin 3; synapsin-3; synapsin-3-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,244,032 - 19,701,571 (+)NCBIGRCr8
mRatBN7.2716,216,055 - 17,808,790 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,376,372 - 17,808,790 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx719,338,160 - 19,770,881 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0721,496,950 - 21,928,082 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0721,277,828 - 21,710,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0723,403,896 - 23,808,602 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,403,891 - 23,808,602 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0723,553,831 - 23,958,150 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,544,439 - 19,940,847 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1719,552,680 - 19,953,765 (+)NCBI
Celera714,630,545 - 15,035,838 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
ATP binding  (IDA,IEA)
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses. Boyken J, etal., Neuron. 2013 Apr 24;78(2):285-97. doi: 10.1016/j.neuron.2013.02.027.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Synapsin III, a novel synapsin with an unusual regulation by Ca2+. Hosaka M and Sudhof TC, J Biol Chem 1998 May 29;273(22):13371-4.
5. Neuronal nitric-oxide synthase localization mediated by a ternary complex with synapsin and CAPON. Jaffrey SR, etal., Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3199-204. Epub 2002 Feb 26.
6. A third member of the synapsin gene family. Kao HT, etal., Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4667-72.
7. A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini. Lam PP, etal., Mol Biol Cell. 2007 Jul;18(7):2473-80. Epub 2007 Apr 18.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10358015   PMID:12040043   PMID:15071120   PMID:17114649   PMID:25843720  


Genomics

Comparative Map Data
Syn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,244,032 - 19,701,571 (+)NCBIGRCr8
mRatBN7.2716,216,055 - 17,808,790 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,376,372 - 17,808,790 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx719,338,160 - 19,770,881 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0721,496,950 - 21,928,082 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0721,277,828 - 21,710,529 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0723,403,896 - 23,808,602 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,403,891 - 23,808,602 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0723,553,831 - 23,958,150 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,544,439 - 19,940,847 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1719,552,680 - 19,953,765 (+)NCBI
Celera714,630,545 - 15,035,838 (+)NCBICelera
Cytogenetic Map7q13NCBI
SYN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382232,507,820 - 33,058,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2232,507,820 - 33,058,381 (-)EnsemblGRCh38hg38GRCh38
GRCh372232,903,807 - 33,454,367 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362231,238,540 - 31,732,683 (-)NCBINCBI36Build 36hg18NCBI36
Build 342231,233,093 - 31,727,237NCBI
Celera2216,710,711 - 17,256,522 (-)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2215,865,721 - 16,411,951 (-)NCBIHuRef
CHM1_12232,867,892 - 33,413,788 (-)NCBICHM1_1
T2T-CHM13v2.02232,971,715 - 33,522,831 (-)NCBIT2T-CHM13v2.0
Syn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391085,884,610 - 86,336,730 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1085,890,989 - 86,334,760 (-)EnsemblGRCm39 Ensembl
GRCm381086,048,746 - 86,498,926 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,055,125 - 86,498,896 (-)EnsemblGRCm38mm10GRCm38
MGSCv371085,511,491 - 85,961,641 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361085,485,308 - 85,928,638 (-)NCBIMGSCv36mm8
Celera1088,022,524 - 88,480,347 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1041.95NCBI
Syn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540541,455,465 - 41,762,920 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540541,450,081 - 41,762,894 (-)NCBIChiLan1.0ChiLan1.0
SYN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22342,435,668 - 43,001,939 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12245,136,351 - 45,700,243 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02213,517,932 - 14,069,661 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12231,373,466 - 31,920,997 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2231,373,604 - 31,866,798 (-)Ensemblpanpan1.1panPan2
SYN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11030,475,134 - 30,927,758 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1030,482,870 - 30,923,257 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1030,458,198 - 30,910,923 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01031,316,595 - 31,770,135 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1031,316,551 - 31,767,063 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11031,058,009 - 31,509,813 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01031,347,117 - 31,799,406 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01031,531,822 - 31,985,721 (+)NCBIUU_Cfam_GSD_1.0
Syn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494513,825,984 - 14,243,677 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364926,876,684 - 7,253,375 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364926,836,441 - 7,253,867 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl512,473,793 - 12,500,076 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1512,017,741 - 12,501,995 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2512,196,607 - 12,291,334 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SYN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11915,330,179 - 15,821,965 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045110,129,396 - 110,678,492 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247501,699,107 - 1,972,252 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247501,663,309 - 1,976,738 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Syn3
14772 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:322
Count of miRNA genes:199
Interacting mature miRNAs:233
Transcripts:ENSRNOT00000037918
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat

Markers in Region
D7Mgh9  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0723,645,249 - 23,645,397NCBIRnor6.0
Rnor_5.0723,795,488 - 23,795,636UniSTSRnor5.0
RGSC_v3.4719,778,187 - 19,778,336RGDRGSC3.4
RGSC_v3.4719,778,188 - 19,778,336UniSTSRGSC3.4
RGSC_v3.1719,788,447 - 19,788,596RGD
Celera714,861,467 - 14,861,602UniSTS
RH 2.0 Map779.3RGD
Cytogenetic Map7q13UniSTS
D7Rat40  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,777,285 - 17,777,527 (+)MAPPERmRatBN7.2
Rnor_6.0723,783,311 - 23,783,552NCBIRnor6.0
Rnor_5.0723,933,259 - 23,933,500UniSTSRnor5.0
RGSC_v3.4719,915,731 - 19,916,213RGDRGSC3.4
RGSC_v3.4719,915,925 - 19,916,166UniSTSRGSC3.4
RGSC_v3.1719,928,649 - 19,929,131RGD
Celera715,011,032 - 15,011,271UniSTS
RH 2.0 Map778.0RGD
SHRSP x BN Map76.87RGD
Cytogenetic Map7q13UniSTS
D7Rat216  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,678,338 - 17,678,552 (+)MAPPERmRatBN7.2
Rnor_6.0723,700,654 - 23,700,867NCBIRnor6.0
Rnor_5.0723,850,893 - 23,851,106UniSTSRnor5.0
RGSC_v3.4719,833,592 - 19,833,806RGDRGSC3.4
RGSC_v3.4719,833,593 - 19,833,806UniSTSRGSC3.4
RGSC_v3.1719,847,222 - 19,847,649RGD
Celera714,916,655 - 14,916,868UniSTS
SHRSP x BN Map76.87RGD
SHRSP x BN Map76.87UniSTS
Cytogenetic Map7q13UniSTS
RH128273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,310 - 17,523,527 (+)MAPPERmRatBN7.2
Rnor_6.0723,545,609 - 23,545,825NCBIRnor6.0
Rnor_5.0723,695,848 - 23,696,064UniSTSRnor5.0
RGSC_v3.4719,678,548 - 19,678,764UniSTSRGSC3.4
Celera714,762,644 - 14,762,860UniSTS
Cytogenetic Map7q13UniSTS
RH129267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,345 - 17,523,536 (+)MAPPERmRatBN7.2
Rnor_6.0723,545,644 - 23,545,834NCBIRnor6.0
Rnor_5.0723,695,883 - 23,696,073UniSTSRnor5.0
RGSC_v3.4719,678,583 - 19,678,773UniSTSRGSC3.4
Celera714,762,679 - 14,762,869UniSTS
Cytogenetic Map7q13UniSTS
RH94615  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,524,335 - 17,524,409 (+)MAPPERmRatBN7.2
Rnor_6.0723,546,634 - 23,546,707NCBIRnor6.0
Rnor_5.0723,696,873 - 23,696,946UniSTSRnor5.0
RGSC_v3.4719,679,573 - 19,679,646UniSTSRGSC3.4
Celera714,763,669 - 14,763,742UniSTS
Cytogenetic Map7q13UniSTS
RH143027  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,679,415 - 17,679,605 (+)MAPPERmRatBN7.2
Rnor_6.0723,701,731 - 23,701,920NCBIRnor6.0
Rnor_5.0723,851,970 - 23,852,159UniSTSRnor5.0
RGSC_v3.4719,834,670 - 19,834,859UniSTSRGSC3.4
Celera714,917,732 - 14,917,921UniSTS
Cytogenetic Map7q13UniSTS
RH144261  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,551,976 - 17,552,083 (+)MAPPERmRatBN7.2
Rnor_6.0723,574,271 - 23,574,377NCBIRnor6.0
Rnor_5.0723,724,510 - 23,724,616UniSTSRnor5.0
RGSC_v3.4719,707,210 - 19,707,316UniSTSRGSC3.4
Celera714,791,244 - 14,791,350UniSTS
Cytogenetic Map7q13UniSTS
BI278238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,117 - 17,523,220 (+)MAPPERmRatBN7.2
Rnor_6.0723,545,416 - 23,545,518NCBIRnor6.0
Rnor_5.0723,695,655 - 23,695,757UniSTSRnor5.0
RGSC_v3.4719,678,355 - 19,678,457UniSTSRGSC3.4
Celera714,762,451 - 14,762,553UniSTS
Cytogenetic Map7q13UniSTS
BF400160  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,802,723 - 17,802,823 (+)MAPPERmRatBN7.2
Rnor_6.0723,808,746 - 23,808,845NCBIRnor6.0
Rnor_5.0723,958,294 - 23,958,393UniSTSRnor5.0
RGSC_v3.4719,940,991 - 19,941,090UniSTSRGSC3.4
Celera715,035,982 - 15,036,081UniSTS
Cytogenetic Map7q13UniSTS
RH135110  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,522,418 - 17,522,611 (+)MAPPERmRatBN7.2
Rnor_6.0723,544,717 - 23,544,909NCBIRnor6.0
Rnor_5.0723,694,956 - 23,695,148UniSTSRnor5.0
RGSC_v3.4719,677,656 - 19,677,848UniSTSRGSC3.4
Celera714,761,752 - 14,761,944UniSTS
Cytogenetic Map7q13UniSTS
RH141014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,521,115 - 17,521,310 (+)MAPPERmRatBN7.2
Rnor_6.0723,543,414 - 23,543,608NCBIRnor6.0
Rnor_5.0723,693,653 - 23,693,847UniSTSRnor5.0
RGSC_v3.4719,676,353 - 19,676,547UniSTSRGSC3.4
Celera714,760,452 - 14,760,643UniSTS
Cytogenetic Map7q13UniSTS
Timp3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,523,945 - 17,524,436 (+)MAPPERmRatBN7.2
Rnor_6.0723,546,244 - 23,546,734NCBIRnor6.0
Rnor_5.0723,696,483 - 23,696,973UniSTSRnor5.0
RGSC_v3.4719,679,183 - 19,679,673UniSTSRGSC3.4
Celera714,763,279 - 14,763,769UniSTS
Cytogenetic Map7q13UniSTS
G45201  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2717,562,016 - 17,562,389 (+)MAPPERmRatBN7.2
mRatBN7.2717,562,046 - 17,562,389 (+)MAPPERmRatBN7.2
Rnor_6.0723,584,341 - 23,584,683NCBIRnor6.0
Rnor_6.0723,584,311 - 23,584,683NCBIRnor6.0
Rnor_5.0723,734,580 - 23,734,922UniSTSRnor5.0
Rnor_5.0723,734,550 - 23,734,922UniSTSRnor5.0
RGSC_v3.4719,717,250 - 19,717,622UniSTSRGSC3.4
RGSC_v3.4719,717,280 - 19,717,622UniSTSRGSC3.4
Celera714,801,206 - 14,801,548UniSTS
Celera714,801,176 - 14,801,548UniSTS
Cytogenetic Map7q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 57
Low 3 35 32 16 18 16 2 3 17 35 41 11 2
Below cutoff 8 25 25 1 25 6 8 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000037918   ⟹   ENSRNOP00000036740
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl717,376,372 - 17,808,790 (+)Ensembl
Rnor_6.0 Ensembl723,403,891 - 23,808,602 (+)Ensembl
RefSeq Acc Id: NM_017109   ⟹   NP_058805
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,264,086 - 19,696,510 (+)NCBI
mRatBN7.2717,376,364 - 17,808,790 (+)NCBI
Rnor_6.0723,403,896 - 23,808,602 (+)NCBI
Rnor_5.0723,553,831 - 23,958,150 (+)NCBI
RGSC_v3.4719,544,439 - 19,940,847 (+)RGD
Celera714,630,545 - 15,035,838 (+)RGD
Sequence:
RefSeq Acc Id: XM_063263102   ⟹   XP_063119172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,246,473 - 19,701,571 (+)NCBI
RefSeq Acc Id: XM_063263103   ⟹   XP_063119173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,244,032 - 19,701,571 (+)NCBI
RefSeq Acc Id: XM_063263104   ⟹   XP_063119174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,246,492 - 19,701,571 (+)NCBI
RefSeq Acc Id: XM_063263105   ⟹   XP_063119175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,246,484 - 19,701,571 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_058805   ⟸   NM_017109
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL),   A0A096MIT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000036740   ⟸   ENSRNOT00000037918
RefSeq Acc Id: XP_063119173   ⟸   XM_063263103
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119172   ⟸   XM_063263102
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119175   ⟸   XM_063263105
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119174   ⟸   XM_063263104
- Peptide Label: isoform X1
- UniProtKB: O70441 (UniProtKB/Swiss-Prot),   A6IFC2 (UniProtKB/TrEMBL)
Protein Domains
Synapsin ATP-binding   Synapsin pre-ATP-grasp

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70441-F1-model_v2 AlphaFold O70441 1-579 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3799 AgrOrtholog
BioCyc Gene G2FUF-34667 BioCyc
Ensembl Genes ENSRNOG00000026866 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055021973 UniProtKB/Swiss-Prot
  ENSRNOG00060026372 UniProtKB/Swiss-Prot
  ENSRNOG00065024903 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000037918 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000037918.6 UniProtKB/Swiss-Prot
  ENSRNOT00055037711 UniProtKB/Swiss-Prot
  ENSRNOT00060045684 UniProtKB/Swiss-Prot
  ENSRNOT00065042793 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1490.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP-grasp fold, B domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ATP_grasp_subdomain_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PreATP-grasp_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin_ATP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin_P_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin_pre-ATP-grasp_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 29130 ENTREZGENE
PANTHER SYNAPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNAPSIN-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Synapsin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synapsin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Syn3 PhenoGen
PRINTS SYNAPSIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SYNAPSIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SYNAPSIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000026866 RatGTEx
  ENSRNOG00055021973 RatGTEx
  ENSRNOG00060026372 RatGTEx
  ENSRNOG00065024903 RatGTEx
Superfamily-SCOP Glutathione synthetase ATP-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MIT7 ENTREZGENE, UniProtKB/TrEMBL
  A6IFC2 ENTREZGENE, UniProtKB/TrEMBL
  O70441 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Syn3  synapsin III  LOC100910134  synapsin-3-like  Data merged from RGD:6500248 737654 PROVISIONAL
2012-07-05 LOC100910134  synapsin-3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2004-09-10 Syn3  synapsin III    synapsin 3  Name updated 1299863 APPROVED
2002-06-10 Syn3  synapsin 3      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function binds ATP with high affinity and ADP with a lower affinity 70029
gene_regulation ATP binding is inhibited by Ca2+ 70029