Slc9a4 (solute carrier family 9 member A4) - Rat Genome Database

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Gene: Slc9a4 (solute carrier family 9 member A4) Rattus norvegicus
Analyze
Symbol: Slc9a4
Name: solute carrier family 9 member A4
RGD ID: 3721
Description: Enables sodium:proton antiporter activity. Predicted to be involved in monoatomic cation transmembrane transport; regulation of intracellular pH; and transepithelial ammonium transport. Predicted to act upstream of or within gastric acid secretion and glandular epithelial cell development. Located in basolateral plasma membrane. Orthologous to human SLC9A4 (solute carrier family 9 member A4); INTERACTS WITH 17beta-estradiol; allethrin; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: na(+)/H(+) exchanger 4; NHE-4; Nhe4; sodium/hydrogen exchanger 4; solute carrier family 9 (sodium/hydrogen exchanger) isoform 4; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 4; solute carrier family 9 (sodium/hydrogen exchanger), member 4; solute carrier family 9 member 4; solute carrier family 9, member 4; solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8950,320,948 - 50,375,336 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl950,320,586 - 50,375,335 (+)EnsemblGRCr8
mRatBN7.2942,825,334 - 42,879,729 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,825,064 - 42,879,422 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx951,327,359 - 51,376,047 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0956,450,043 - 56,498,733 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,725,727 - 54,774,484 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0947,281,821 - 47,334,755 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,281,961 - 47,328,839 (+)Ensemblrn6Rnor6.0
Rnor_5.0946,965,557 - 47,018,293 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4939,725,135 - 39,773,368 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera940,568,530 - 40,616,779 (+)NCBICelera
RGSC_v3.1939,726,548 - 39,774,782 (+)NCBI
Cytogenetic Map9q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Characterization of the rat Na+/H+ exchanger isoform NHE4 and localization in rat hippocampus. Bookstein C, etal., Am J Physiol. 1996 Nov;271(5 Pt 1):C1629-38. doi: 10.1152/ajpcell.1996.271.5.C1629.
2. Localization and functional characterization of Na+/H+ exchanger isoform NHE4 in rat thick ascending limbs. Chambrey R, etal., Am J Physiol Renal Physiol. 2001 Oct;281(4):F707-17. doi: 10.1152/ajprenal.2001.281.4.F707.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins. Orlowski J, etal., J Biol Chem 1992 May 5;267(13):9331-9.
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15684419   PMID:22049213   PMID:23509787   PMID:26078707  


Genomics

Comparative Map Data
Slc9a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8950,320,948 - 50,375,336 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl950,320,586 - 50,375,335 (+)EnsemblGRCr8
mRatBN7.2942,825,334 - 42,879,729 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl942,825,064 - 42,879,422 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx951,327,359 - 51,376,047 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0956,450,043 - 56,498,733 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0954,725,727 - 54,774,484 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0947,281,821 - 47,334,755 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl947,281,961 - 47,328,839 (+)Ensemblrn6Rnor6.0
Rnor_5.0946,965,557 - 47,018,293 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4939,725,135 - 39,773,368 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera940,568,530 - 40,616,779 (+)NCBICelera
RGSC_v3.1939,726,548 - 39,774,782 (+)NCBI
Cytogenetic Map9q22NCBI
SLC9A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382102,473,226 - 102,533,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2102,473,226 - 102,533,972 (+)Ensemblhg38GRCh38
GRCh372103,089,685 - 103,150,431 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362102,456,194 - 102,516,863 (+)NCBIBuild 36Build 36hg18NCBI36
Celera297,290,912 - 97,351,604 (+)NCBICelera
Cytogenetic Map2q12.1NCBI
HuRef296,854,147 - 96,914,821 (+)NCBIHuRef
CHM1_12103,094,074 - 103,154,769 (+)NCBICHM1_1
T2T-CHM13v2.02102,932,202 - 102,992,943 (+)NCBIT2T-CHM13v2.0
Slc9a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39140,619,146 - 40,670,188 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl140,619,241 - 40,669,885 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38140,579,986 - 40,630,731 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl140,580,081 - 40,630,725 (+)Ensemblmm10GRCm38
MGSCv37140,637,072 - 40,687,576 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36140,524,747 - 40,574,199 (+)NCBIMGSCv36mm8
Celera140,395,812 - 40,446,178 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map119.51NCBI
Slc9a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554707,936,532 - 7,984,777 (+)Ensembl
ChiLan1.0NW_0049554707,936,677 - 7,989,946 (+)NCBIChiLan1.0ChiLan1.0
SLC9A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21225,165,483 - 25,228,594 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A25,168,248 - 25,231,359 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A99,280,738 - 99,341,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A103,566,298 - 103,626,975 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A103,566,128 - 103,626,975 (+)EnsemblpanPan2panpan1.1
SLC9A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11040,492,031 - 40,560,423 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1040,492,613 - 40,560,472 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1040,413,457 - 40,486,515 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01041,358,013 - 41,426,831 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1041,358,399 - 41,426,351 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11041,068,471 - 41,141,354 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01041,349,102 - 41,422,016 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01041,541,819 - 41,614,694 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc9a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629289,943,031 - 89,999,402 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367131,134,059 - 1,186,145 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367131,134,059 - 1,186,145 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC9A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl351,687,642 - 51,749,636 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1351,686,001 - 51,749,996 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2354,166,243 - 54,230,077 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC9A4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1146,136,179 - 6,197,632 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl146,137,368 - 6,195,786 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041173,819,885 - 173,879,102 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc9a4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247496,972,904 - 7,024,665 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247496,972,364 - 7,025,929 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc9a4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14116,797,912 - 116,851,317 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc9a4
465 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:43
Interacting mature miRNAs:50
Transcripts:ENSRNOT00000065234
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9534647950346479Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9875049253750492Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9621499551214995Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9875049253750492Rat
7207805Bmd88Bone mineral density QTL 884femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)93125043265651574Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9534647950416711Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9621499551214995Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)93145606157460683Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat

Markers in Region
D9Rat124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,864,924 - 42,865,057 (+)MAPPERmRatBN7.2
Rnor_6.0947,319,756 - 47,319,888NCBIRnor6.0
Rnor_5.0947,004,007 - 47,004,139UniSTSRnor5.0
RGSC_v3.4939,764,582 - 39,764,715RGDRGSC3.4
RGSC_v3.4939,764,583 - 39,764,715UniSTSRGSC3.4
Celera940,608,076 - 40,608,208UniSTS
RGSC_v3.1939,765,996 - 39,766,129RGD
SHRSP x BN Map937.7198UniSTS
SHRSP x BN Map937.7198RGD
Cytogenetic Map9q21UniSTS
D9Mco26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2942,831,017 - 42,831,226 (+)MAPPERmRatBN7.2
Rnor_6.0947,287,912 - 47,288,120NCBIRnor6.0
Rnor_5.0946,972,136 - 46,972,344UniSTSRnor5.0
RGSC_v3.4939,731,087 - 39,731,295UniSTSRGSC3.4
Celera940,574,481 - 40,574,689UniSTS
Cytogenetic Map9q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 9 5 87 20 24 5 15 5 6 139 32 2 76 81 73 19 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000065234   ⟹   ENSRNOP00000059258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl950,320,586 - 50,375,335 (+)Ensembl
mRatBN7.2 Ensembl942,825,064 - 42,879,422 (+)Ensembl
Rnor_6.0 Ensembl947,281,961 - 47,328,839 (+)Ensembl
RefSeq Acc Id: NM_001413317   ⟹   NP_001400246
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8950,320,948 - 50,375,336 (+)NCBI
mRatBN7.2942,825,334 - 42,879,729 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001400246 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41703 (Get FASTA)   NCBI Sequence Viewer  
  EDL99168 (Get FASTA)   NCBI Sequence Viewer  
  EDL99169 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000059258
GenBank Protein P26434 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000059258   ⟸   ENSRNOT00000065234
RefSeq Acc Id: NP_001400246   ⟸   NM_001413317
- Peptide Label: precursor
- UniProtKB: G3V9T3 (UniProtKB/TrEMBL),   A6INP1 (UniProtKB/TrEMBL),   A6INP2 (UniProtKB/TrEMBL)
Protein Domains
Cation/H+ exchanger transmembrane   Sodium/hydrogen exchanger regulatory region

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P26434-F1-model_v2 AlphaFold P26434 1-717 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696633
Promoter ID:EPDNEW_R7158
Type:single initiation site
Name:Slc9a4_1
Description:solute carrier family 9 member A4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0947,281,938 - 47,281,998EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3721 AgrOrtholog
BioCyc Gene G2FUF-27720 BioCyc
Ensembl Genes ENSRNOG00000015306 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000065234 ENTREZGENE
Gene3D-CATH 6.10.140.1330 UniProtKB/Swiss-Prot
  6.10.250.1040 UniProtKB/Swiss-Prot
  6.10.250.2020 UniProtKB/Swiss-Prot
InterPro Cation/H_exchanger UniProtKB/Swiss-Prot
  Cation/H_exchanger_CPA1 UniProtKB/Swiss-Prot
  Na/H_exchanger_2 UniProtKB/Swiss-Prot
  NaH_exchanger UniProtKB/Swiss-Prot
  NHE_CaM-bd UniProtKB/Swiss-Prot
NCBI Gene 24785 ENTREZGENE
PANTHER PTHR10110 UniProtKB/Swiss-Prot
  PTHR10110:SF103 UniProtKB/Swiss-Prot
Pfam Na_H_Exchanger UniProtKB/Swiss-Prot
  NEXCaM_BD UniProtKB/Swiss-Prot
PhenoGen Slc9a4 PhenoGen
PRINTS NAHEXCHNGR UniProtKB/Swiss-Prot
  NAHEXCHNGR2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015306 RatGTEx
UniProt A6INP1 ENTREZGENE, UniProtKB/TrEMBL
  A6INP2 ENTREZGENE, UniProtKB/TrEMBL
  G3V9T3 ENTREZGENE, UniProtKB/TrEMBL
  P26434 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Slc9a4  solute carrier family 9 member A4  Slc9a4  solute carrier family 9 member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-24 Slc9a4  solute carrier family 9 member 4  Slc9a4  solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-16 Slc9a4  solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4  Slc9a4  solute carrier family 9 (sodium/hydrogen exchanger), member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-15 Slc9a4  solute carrier family 9 (sodium/hydrogen exchanger), member 4  Slc9a4  solute carrier family 9, member 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Slc9a4  solute carrier family 9, member 4    Solute carrier family 9 (sodium/hydrogen exchanger), isoform 4  Name updated 629478 APPROVED
2002-06-10 Slc9a4  Solute carrier family 9 (sodium/hydrogen exchanger), isoform 4      Symbol and Name status set to approved 70586 APPROVED