Slc3a1 (solute carrier family 3 member 1) - Rat Genome Database

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Gene: Slc3a1 (solute carrier family 3 member 1) Rattus norvegicus
Analyze
Symbol: Slc3a1
Name: solute carrier family 3 member 1
RGD ID: 3709
Description: Predicted to enable protein heterodimerization activity. Involved in amino acid transport. Located in vacuolar membrane. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC3A1 (solute carrier family 3 member 1); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: amino acid transporter heavy chain SLC3A1; b(0,+)-type amino acid transport protein; b(0,+)-type amino acid transporter-related heavy chain; D2; NAA-TR; NBAT; neutral and basic amino acid transport protein rBAT; rBAT; solute carrier family 3 (amino acid transporter heavy chain), member 1; solute carrier family 3, member 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,361,037 - 15,396,695 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl615,361,046 - 15,394,775 (-)EnsemblGRCr8
mRatBN7.269,608,169 - 9,641,881 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,608,178 - 9,641,907 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx69,897,026 - 9,930,636 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,206,403 - 10,240,011 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.069,727,975 - 9,761,655 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd616,793,710 - 16,827,462 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive616,233,732 - 16,267,480 (-)NCBILyon_Normotensive
Lyon_Hypertensive614,023,132 - 14,056,744 (-)NCBILyon_Hypertensive
F344_StmMcwi613,150,984 - 13,184,669 (-)NCBIF344_StmMcwi
Rnor_6.068,284,937 - 8,318,649 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl68,284,878 - 8,318,674 (+)Ensemblrn6Rnor6.0
Rnor_5.068,217,549 - 8,251,133 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.468,385,186 - 8,419,465 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera69,332,403 - 9,366,072 (-)NCBICelera
RGSC_v3.168,385,185 - 8,419,461 (+)NCBI
Cytogenetic Map6q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
ampicillin  (EXP)
atrazine  (EXP)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
clopidogrel  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dorsomorphin  (ISO)
entinostat  (ISO)
eugenol  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
furan  (EXP)
genistein  (ISO)
gentamycin  (EXP)
GW 4064  (ISO)
inulin  (ISO)
L-cysteine  (ISO)
L-cystine  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
metronidazole  (EXP)
neomycin  (EXP)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
okadaic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
progesterone  (ISO)
resveratrol  (EXP)
rifampicin  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
Se-methyl-L-selenocysteine  (ISO)
Se-methylselenocysteine  (ISO)
selenocystine  (ISO)
selenomethionine  (ISO)
senecionine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
tamoxifen  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
tributylstannane  (EXP)
trichloroethene  (ISO)
triptonide  (ISO)
vancomycin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Cystinuria caused by mutations in rBAT, a gene involved in the transport of cystine. Calonge MJ, etal., Nat Genet. 1994 Apr;6(4):420-5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Membrane topology of the rat kidney neutral and basic amino acid transporter. Mosckovitz R, etal., FASEB J. 1994 Oct;8(13):1069-74.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Regional and subcellular distribution of a neutral and basic amino acid transporter in forebrain neurons containing nitric oxide synthase. Pickel VM, etal., J Comp Neurol. 1999 Feb 22;404(4):459-72.
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. GOA pipeline RGD automated data pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Expression cloning of a Na(+)-independent neutral amino acid transporter from rat kidney. Tate SS, etal., Proc Natl Acad Sci U S A 1992 Jan 1;89(1):1-5.
14. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
15. Oligomeric structure of a renal cystine transporter: implications in cystinuria. Wang Y and Tate SS, FEBS Lett. 1995 Jul 17;368(2):389-92.
16. Cloning of a rat kidney cDNA that stimulates dibasic and neutral amino acid transport and has sequence similarity to glucosidases. Wells RG and Hediger MA, Proc Natl Acad Sci U S A 1992 Jun 15;89(12):5596-600.
Additional References at PubMed
PMID:8052618   PMID:10506124   PMID:12167606   PMID:12865426   PMID:15489334   PMID:19056867   PMID:23376485  


Genomics

Comparative Map Data
Slc3a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8615,361,037 - 15,396,695 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl615,361,046 - 15,394,775 (-)EnsemblGRCr8
mRatBN7.269,608,169 - 9,641,881 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl69,608,178 - 9,641,907 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx69,897,026 - 9,930,636 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0610,206,403 - 10,240,011 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.069,727,975 - 9,761,655 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd616,793,710 - 16,827,462 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive616,233,732 - 16,267,480 (-)NCBILyon_Normotensive
Lyon_Hypertensive614,023,132 - 14,056,744 (-)NCBILyon_Hypertensive
F344_StmMcwi613,150,984 - 13,184,669 (-)NCBIF344_StmMcwi
Rnor_6.068,284,937 - 8,318,649 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl68,284,878 - 8,318,674 (+)Ensemblrn6Rnor6.0
Rnor_5.068,217,549 - 8,251,133 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.468,385,186 - 8,419,465 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera69,332,403 - 9,366,072 (-)NCBICelera
RGSC_v3.168,385,185 - 8,419,461 (+)NCBI
Cytogenetic Map6q12NCBI
SLC3A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38244,275,480 - 44,322,437 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl244,275,458 - 44,321,494 (+)Ensemblhg38GRCh38
GRCh37244,502,619 - 44,548,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36244,356,103 - 44,401,448 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34244,414,249 - 44,459,588NCBI
Celera244,341,552 - 44,386,916 (+)NCBICelera
Cytogenetic Map2p21NCBI
HuRef244,239,242 - 44,284,624 (+)NCBIHuRef
CHM1_1244,430,299 - 44,475,664 (+)NCBICHM1_1
T2T-CHM13v2.0244,280,847 - 44,327,754 (+)NCBIT2T-CHM13v2.0
Slc3a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391785,335,775 - 85,371,669 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1785,335,804 - 85,371,664 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381785,028,347 - 85,064,241 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1785,028,376 - 85,064,236 (+)Ensemblmm10GRCm38
MGSCv371785,427,687 - 85,463,581 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361784,936,718 - 84,983,241 (+)NCBIMGSCv36mm8
Celera1789,390,574 - 89,425,929 (+)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1755.17NCBI
Slc3a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544111,381,441 - 11,418,025 (+)Ensembl
ChiLan1.0NW_00495544111,381,390 - 11,418,193 (+)NCBIChiLan1.0ChiLan1.0
SLC3A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21282,089,000 - 82,146,430 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A82,092,970 - 82,150,400 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A44,371,328 - 44,419,611 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A45,307,885 - 45,356,055 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A45,307,885 - 45,355,386 (+)EnsemblpanPan2panpan1.1
SLC3A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11046,690,555 - 46,737,417 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1046,685,137 - 46,737,147 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1046,562,101 - 46,597,364 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01047,580,243 - 47,618,780 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1047,580,243 - 47,615,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11047,287,361 - 47,322,625 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01047,578,444 - 47,613,677 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01047,760,850 - 47,796,315 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Slc3a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629236,243,175 - 36,276,008 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365087,672,223 - 7,703,961 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365087,672,274 - 7,703,962 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC3A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl396,157,380 - 96,215,454 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1396,157,387 - 96,201,057 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23102,312,692 - 102,371,561 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC3A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11462,924,906 - 62,971,268 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1462,925,443 - 62,971,252 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604548,910,733 - 48,957,571 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc3a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473825,768,573 - 25,802,716 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473825,762,064 - 25,802,407 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc3a1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v177,869,823 - 7,902,937 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc3a1
227 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:38
Count of miRNA genes:35
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000009581
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6125740059Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6120510098Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
8693690Alc35Alcohol consumption QTL 352.20.606drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)61371716927053860Rat

Markers in Region
RH132752  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.269,608,328 - 9,608,534 (-)MAPPERmRatBN7.2
Rnor_6.068,318,284 - 8,318,489NCBIRnor6.0
Rnor_5.068,250,768 - 8,250,973UniSTSRnor5.0
RGSC_v3.468,419,100 - 8,419,305UniSTSRGSC3.4
Celera69,332,563 - 9,332,768UniSTS
Cytogenetic Map6q12UniSTS
AW535278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.269,610,813 - 9,610,967 (-)MAPPERmRatBN7.2
Rnor_6.068,315,851 - 8,316,004NCBIRnor6.0
Rnor_5.068,248,335 - 8,248,488UniSTSRnor5.0
RGSC_v3.468,416,667 - 8,416,820UniSTSRGSC3.4
Celera69,335,053 - 9,335,206UniSTS
Cytogenetic Map6q12UniSTS
RH139082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.269,609,676 - 9,609,859 (-)MAPPERmRatBN7.2
Rnor_6.068,316,959 - 8,317,141NCBIRnor6.0
Rnor_5.068,249,443 - 8,249,625UniSTSRnor5.0
RGSC_v3.468,417,775 - 8,417,957UniSTSRGSC3.4
Celera69,333,911 - 9,334,093UniSTS
Cytogenetic Map6q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 11 39 118 83 82 51 43 51 6 258 106 1 99 81 79 31 2 2

Sequence


Ensembl Acc Id: ENSRNOT00000009581   ⟹   ENSRNOP00000009581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl615,361,046 - 15,394,775 (-)Ensembl
mRatBN7.2 Ensembl69,608,178 - 9,641,907 (-)Ensembl
Rnor_6.0 Ensembl68,284,878 - 8,318,674 (+)Ensembl
RefSeq Acc Id: NM_017216   ⟹   NP_058912
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,361,037 - 15,394,749 (-)NCBI
mRatBN7.269,608,169 - 9,641,881 (-)NCBI
Dahl_SR_JrHsd616,793,710 - 16,827,462 (-)NCBI
Lyon_Normotensive616,233,732 - 16,267,480 (-)NCBI
Lyon_Hypertensive614,023,132 - 14,056,744 (-)NCBI
F344_StmMcwi613,150,984 - 13,184,669 (-)NCBI
Rnor_6.068,284,937 - 8,318,649 (+)NCBI
Rnor_5.068,217,549 - 8,251,133 (+)NCBI
RGSC_v3.468,385,186 - 8,419,465 (+)RGD
Celera69,332,403 - 9,366,072 (-)RGD
Sequence:
RefSeq Acc Id: XM_063261585   ⟹   XP_063117655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8615,361,037 - 15,396,695 (-)NCBI
RefSeq Acc Id: NP_058912   ⟸   NM_017216
- UniProtKB: Q62672 (UniProtKB/Swiss-Prot),   Q64319 (UniProtKB/Swiss-Prot),   A6H9H4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009581   ⟸   ENSRNOT00000009581
RefSeq Acc Id: XP_063117655   ⟸   XM_063261585
- Peptide Label: isoform X1
Protein Domains
Glycosyl hydrolase family 13 catalytic

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64319-F1-model_v2 AlphaFold Q64319 1-683 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694379
Promoter ID:EPDNEW_R4904
Type:initiation region
Name:Slc3a1_1
Description:solute carrier family 3 member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.068,284,903 - 8,284,963EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3709 AgrOrtholog
BioCyc Gene G2FUF-38653 BioCyc
Ensembl Genes ENSRNOG00000007006 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000009581 ENTREZGENE
  ENSRNOT00000009581.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.1180 UniProtKB/Swiss-Prot
  Glycosidases UniProtKB/Swiss-Prot
  Oligo-1,6-glucosidase, Domain 2 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7110514 IMAGE-MGC_LOAD
InterPro Glyco_hydro_13_cat_dom UniProtKB/Swiss-Prot
  Glyco_hydro_b UniProtKB/Swiss-Prot
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot
  O16G_dom_2 UniProtKB/Swiss-Prot
KEGG Report rno:29484 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93505 IMAGE-MGC_LOAD
NCBI Gene 29484 ENTREZGENE
PANTHER ALPHA-AMYLASE FAMILY MEMBER UniProtKB/Swiss-Prot
  NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT UniProtKB/Swiss-Prot
Pfam Alpha-amylase UniProtKB/Swiss-Prot
PhenoGen Slc3a1 PhenoGen
RatGTEx ENSRNOG00000007006 RatGTEx
SMART Aamy UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot
TIGR TC207343
UniProt A6H9H4 ENTREZGENE, UniProtKB/TrEMBL
  Q62672 ENTREZGENE
  Q64319 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q62672 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Slc3a1  solute carrier family 3 member 1  Slc3a1  solute carrier family 3 (amino acid transporter heavy chain), member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-03-16 Slc3a1  solute carrier family 3 (amino acid transporter heavy chain), member 1  Slc3a1  solute carrier family 3, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2003-04-09 Slc3a1  solute carrier family 3, member 1    solute carrier family 3, member 1   Name updated 629478 APPROVED
2002-06-10 Slc3a1  solute carrier family 3, member 1       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_domains appears to have a single transmembrane domain 70013
gene_expression mRNA expressed specifically in kidney and intestine 70013
gene_protein putative protein is of 78 kDa 70013