Slc14a2 (solute carrier family 14 member 2) - Rat Genome Database

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Gene: Slc14a2 (solute carrier family 14 member 2) Rattus norvegicus
Analyze
Symbol: Slc14a2
Name: solute carrier family 14 member 2
RGD ID: 3689
Description: Enables urea transmembrane transporter activity. Involved in urea transport. Located in apical plasma membrane. Orthologous to human SLC14A2 (solute carrier family 14 member 2); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; INTERACTS WITH (R)-noradrenaline; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: plasma membrane urea transporter; Slc14a1_v3; Slc14a1_v4; Slc14a2_v4; Slc14a2T; solute carrier family 14 (urea transporter), member 2; solute carrier family 14 (urea transporter), member 2, variant 4; solute carrier family 14 (urea transporter), member 2T; solute carrier family 14, member 2; testName; testSymbol; urea transport protein; Urea transporter; urea transporter 2; urea transporter UT-A2c; urea transporter UT-A2d; urea transporter, kidney; UrT1-C; UrT1-D; UT-A1; UT-A2; UT-A4; UTA3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Slc14a2_v1 ; Slc14a2_v2 ; Slc14a2_v3
Latest Assembly: GRCr8 - GRCr8 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8 Ensembl1873,887,575 - 73,953,570 (-)EnsemblGRCr8
mRatBN7.21871,612,460 - 72,039,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1871,612,460 - 71,792,968 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1873,711,878 - 74,138,787 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01874,381,161 - 74,808,122 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01872,237,749 - 72,664,708 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01874,508,070 - 74,941,389 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1874,546,220 - 74,688,551 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl1874,508,069 - 74,542,077 (-)Ensemblrn6Rnor6.0
Rnor_5.01874,185,426 - 74,617,691 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41875,071,416 - 75,499,738 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1870,129,421 - 70,555,892 (-)NCBICelera
RGSC_v3.11875,144,693 - 75,325,630 (-)NCBI
Cytogenetic Map18q12.3NCBI



Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Molecular characterization of a novel UT-A urea transporter isoform (UT-A5) in testis. Fenton RA, etal., Am J Physiol Cell Physiol 2000 Nov;279(5):C1425-31.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Cloning and characterization of two new isoforms of the rat kidney urea transporter: UT-A3 and UT-A4. Karakashian A, etal., J Am Soc Nephrol 1999 Feb;10(2):230-7.
5. Expression of urea transporters in the developing rat kidney. Kim YH, etal., Am J Physiol Renal Physiol 2002 Mar;282(3):F530-40.
6. Vasopressin increases plasma membrane accumulation of urea transporter UT-A1 in rat inner medullary collecting ducts. Klein JD, etal., J Am Soc Nephrol. 2006 Oct;17(10):2680-6. doi: 10.1681/ASN.2006030246. Epub 2006 Sep 7.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. The UT-A1 urea transporter interacts with snapin, a SNARE-associated protein. Mistry AC, etal., J Biol Chem. 2007 Oct 12;282(41):30097-106. Epub 2007 Aug 16.
9. Cloning of the rat Slc14a2 gene and genomic organization of the UT-A urea transporter. Nakayama Y, etal., Biochim Biophys Acta 2001 Mar 19;1518(1-2):19-26.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Molecular characterization of a novel urea transporter from kidney inner medullary collecting ducts. Shayakul C, etal., Am J Physiol Renal Physiol 2001 Mar;280(3):F487-94.
16. Molecular cloning and characterization of the vasopressin-regulated urea transporter of rat kidney collecting ducts. Shayakul C, etal., J Clin Invest 1996 Dec 1;98(11):2580-7.
17. Cloning and regulation of expression of the rat kidney urea transporter (rUT2). Smith CP, etal., J Clin Invest 1995 Sep;96(3):1556-63.
18. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:8889548   PMID:11547347   PMID:15251864   PMID:15886274   PMID:16788141   PMID:17264983   PMID:18448630   PMID:18495802   PMID:18715940   PMID:18784257   PMID:19034881   PMID:19369293  
PMID:19661162   PMID:20071460   PMID:20457831   PMID:21127847   PMID:21965602   PMID:22535801   PMID:23620790   PMID:25377918   PMID:25613743   PMID:25995111   PMID:26423860   PMID:29046292  


Genomics

Comparative Map Data
Slc14a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8 Ensembl1873,887,575 - 73,953,570 (-)EnsemblGRCr8
mRatBN7.21871,612,460 - 72,039,462 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1871,612,460 - 71,792,968 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1873,711,878 - 74,138,787 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01874,381,161 - 74,808,122 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01872,237,749 - 72,664,708 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01874,508,070 - 74,941,389 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1874,546,220 - 74,688,551 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl1874,508,069 - 74,542,077 (-)Ensemblrn6Rnor6.0
Rnor_5.01874,185,426 - 74,617,691 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41875,071,416 - 75,499,738 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1870,129,421 - 70,555,892 (-)NCBICelera
RGSC_v3.11875,144,693 - 75,325,630 (-)NCBI
Cytogenetic Map18q12.3NCBI
SLC14A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381845,167,963 - 45,683,688 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1845,212,995 - 45,683,688 (+)Ensemblhg38GRCh38
GRCh371842,747,928 - 43,263,653 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361841,448,764 - 41,517,070 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341841,448,763 - 41,517,056NCBI
Celera1840,003,033 - 40,071,376 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
HuRef1839,650,605 - 40,120,200 (+)NCBIHuRef
CHM1_11842,719,963 - 43,190,313 (+)NCBICHM1_1
T2T-CHM13v2.01845,359,240 - 45,874,622 (+)NCBIT2T-CHM13v2.0
Slc14a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391878,189,359 - 78,640,165 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1878,189,363 - 78,640,157 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381878,146,144 - 78,596,950 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1878,146,148 - 78,596,942 (-)Ensemblmm10GRCm38
MGSCv371878,342,883 - 78,793,689 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361878,308,224 - 78,759,020 (-)NCBIMGSCv36mm8
Celera1879,287,387 - 79,738,811 (-)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1852.53NCBI
Slc14a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540231,115,937 - 31,285,228 (+)Ensembl
ChiLan1.0NW_00495540230,877,808 - 31,283,983 (+)NCBIChiLan1.0ChiLan1.0
SLC14A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21763,050,743 - 63,110,153 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11848,743,343 - 48,802,753 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01838,766,994 - 38,966,124 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11842,034,675 - 42,506,485 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1842,448,067 - 42,506,485 (+)EnsemblpanPan2panpan1.1
SLC14A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1745,435,387 - 45,868,977 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl745,431,450 - 45,490,430 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha745,019,276 - 45,354,276 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0745,413,685 - 45,883,152 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl745,417,038 - 45,441,280 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1745,113,465 - 45,589,519 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0745,166,683 - 45,635,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0745,451,135 - 45,920,415 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101965929
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494441,732,909 - 41,759,360 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365171,061,119 - 1,104,768 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365171,060,311 - 1,104,775 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC14A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl195,255,632 - 95,320,542 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1194,838,955 - 95,322,748 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21105,368,929 - 105,382,578 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC14A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11835,209,672 - 35,684,142 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1835,209,267 - 35,404,626 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660509,581,381 - 9,639,922 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc14a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247789,330,064 - 9,379,942 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247788,943,209 - 9,379,942 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc14a2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11553,578,776 - 54,003,881 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:277
Count of miRNA genes:149
Interacting mature miRNAs:171
Transcripts:ENSRNOT00000022417, ENSRNOT00000071290, ENSRNOT00000072665
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
20 9 25 122 49 50 13 42 13 12 250 92 7 93 119 118 37 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001110270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC114093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC120683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC129683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF041788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF042167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF214484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK483468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK844529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT598256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KT598257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U77971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000078016   ⟹   ENSRNOP00000073854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1873,925,725 - 73,953,570 (-)Ensembl
mRatBN7.2 Ensembl1871,650,629 - 71,792,968 (-)Ensembl
Rnor_6.0 Ensembl1874,546,220 - 74,688,551 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078519   ⟹   ENSRNOP00000074116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1873,888,174 - 73,900,418 (-)Ensembl
mRatBN7.2 Ensembl1871,619,933 - 71,646,486 (-)Ensembl
Rnor_6.0 Ensembl1874,508,069 - 74,542,077 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079899   ⟹   ENSRNOP00000068708
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1873,887,575 - 73,953,570 (-)Ensembl
mRatBN7.2 Ensembl1871,612,460 - 71,792,968 (-)Ensembl
Rnor_6.0 Ensembl1874,546,441 - 74,574,052 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000091439   ⟹   ENSRNOP00000071655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1874,546,474 - 74,574,052 (-)Ensembl
RefSeq Acc Id: NM_001110270   ⟹   NP_001103740
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21871,612,460 - 71,646,486 (-)NCBI
Rnor_6.01874,508,070 - 74,542,077 (-)NCBI
Rnor_5.01874,185,426 - 74,617,691 (-)NCBI
RGSC_v3.41875,071,416 - 75,499,738 (-)RGD
Celera1870,129,421 - 70,163,429 (-)NCBI
Sequence:
RefSeq Acc Id: NM_019347   ⟹   NP_062220
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21871,612,460 - 72,039,462 (-)NCBI
Rnor_6.01874,508,070 - 74,941,389 (-)NCBI
Rnor_5.01874,185,426 - 74,617,691 (-)NCBI
RGSC_v3.41875,071,416 - 75,499,738 (-)RGD
Celera1870,129,421 - 70,555,892 (-)RGD
Sequence:
RefSeq Acc Id: NM_177962   ⟹   NP_808877
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21871,650,627 - 72,039,462 (-)NCBI
Rnor_6.01874,546,218 - 74,941,389 (-)NCBI
Rnor_5.01874,185,426 - 74,617,691 (-)NCBI
RGSC_v3.41875,071,416 - 75,499,738 (-)RGD
Celera1870,167,570 - 70,555,892 (-)NCBI
Sequence:
RefSeq Acc Id: NP_062220   ⟸   NM_019347
- Peptide Label: isoform 1
- UniProtKB: Q9Z2R3 (UniProtKB/Swiss-Prot),   Q9WTT8 (UniProtKB/Swiss-Prot),   Q9R1Y7 (UniProtKB/Swiss-Prot),   Q62668 (UniProtKB/Swiss-Prot),   A6KMY1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_808877   ⟸   NM_177962
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K6L0 (UniProtKB/TrEMBL),   A6KMY3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103740   ⟸   NM_001110270
- Peptide Label: isoform 3
- UniProtKB: A6KMY2 (UniProtKB/TrEMBL),   A0A120KA92 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068708   ⟸   ENSRNOT00000079899
Ensembl Acc Id: ENSRNOP00000073854   ⟸   ENSRNOT00000078016
Ensembl Acc Id: ENSRNOP00000071655   ⟸   ENSRNOT00000091439
Ensembl Acc Id: ENSRNOP00000074116   ⟸   ENSRNOT00000078519

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62668-F1-model_v2 AlphaFold Q62668 1-929 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3689 AgrOrtholog
BioCyc Gene G2FUF-6922 BioCyc
Ensembl Genes ENSRNOG00000056021 Ensembl
  ENSRNOG00000061714 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000078016 ENTREZGENE
  ENSRNOT00000079899 ENTREZGENE
Gene3D-CATH 1.10.3430.10 UniProtKB/Swiss-Prot
InterPro Ammonium/urea_transptr UniProtKB/Swiss-Prot
  Urea_transporter UniProtKB/Swiss-Prot
KEGG Report rno:54302 UniProtKB/Swiss-Prot
NCBI Gene 54302 ENTREZGENE
PANTHER PTHR10464 UniProtKB/Swiss-Prot
  UREA TRANSPORTER 2 UniProtKB/Swiss-Prot
Pfam PF03253 UniProtKB/Swiss-Prot
PhenoGen Slc14a2 PhenoGen
RatGTEx ENSRNOG00000056021 RatGTEx
  ENSRNOG00000061714 RatGTEx
TIGR TC235944
UniProt A0A0G2JTG8_RAT UniProtKB/TrEMBL
  A0A0G2K6L0 ENTREZGENE, UniProtKB/TrEMBL
  A0A120KA92 ENTREZGENE, UniProtKB/TrEMBL
  A6KMX9_RAT UniProtKB/TrEMBL
  A6KMY0_RAT UniProtKB/TrEMBL
  A6KMY1 ENTREZGENE, UniProtKB/TrEMBL
  A6KMY2 ENTREZGENE, UniProtKB/TrEMBL
  A6KMY3 ENTREZGENE, UniProtKB/TrEMBL
  A6KMY4_RAT UniProtKB/TrEMBL
  Q62668 ENTREZGENE
  Q9R1Y7 ENTREZGENE
  Q9WTT8 ENTREZGENE
  Q9Z2R3 ENTREZGENE
  UT2_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q9R1Y7 UniProtKB/Swiss-Prot
  Q9WTT8 UniProtKB/Swiss-Prot
  Q9Z2R3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Slc14a2  solute carrier family 14 member 2  Slc14a2  solute carrier family 14 (urea transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Slc14a2  solute carrier family 14 (urea transporter), member 2  Slc14a2_v4  solute carrier family 14 (urea transporter), member 2, variant 4  Data merged from RGD:70071 737654 PROVISIONAL
2008-06-23 Slc14a2T  solute carrier family 14 (urea transporter), member 2T  Slc14a2  solute carrier family 14 (urea transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-23 Slc14a2  solute carrier family 14 (urea transporter), member 2  Slc14a2T  solute carrier family 14 (urea transporter), member 2T  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-10 testSymbol  testName  Slc14a2  solute carrier family 14 (urea transporter), member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-10 Slc14a2  solute carrier family 14 (urea transporter), member 2  testSymbol  testName  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Slc14a2_v4  solute carrier family 14, member 2, variant 4      Symbol and Name status set to approved 1299863 APPROVED
2004-09-10 Slc14a2  solute carrier family 14 (urea transporter), member 2    solute carrier family 14, member 2  Name updated 1299863 APPROVED
2003-03-12 Slc14a1_v4  solute carrier family 14, member 1, variant 4  UrT1-D    Data merged from RGD:620582 628472 PROVISIONAL
2002-11-06 Slc14a1_v4  solute carrier family 14, member 1, variant 4      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 UrT1-D        Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Slc14a2  solute carrier family 14, member 2      Symbol and Name status set to approved 70586 APPROVED
2002-06-10 Slc14a1_v4  solute carrier family 14, member 1, variant 4      Symbol and Name updated 70585 PROVISIONAL
2002-02-20 Slc14a2  solute carrier family 14 (urea transporter), member 2      Name updated to reflect Human and Mouse nomenclature 70282 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in the renal outer and inner medulla but not in the cortex 68904
gene_function transports urea 68889
gene_function transports urea 68904
gene_process plays a role in regulating urea accumulation in the kidney inner medulla and in maintaining water and nitrogen balance 68904
gene_protein 466 amino acids 68904