Gene: Rgs8 (regulator of G-protein signaling 8) Rattus norvegicus
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Symbol:
Rgs8
Name:
regulator of G-protein signaling 8
RGD ID:
3571
Description:
Enables G-protein alpha-subunit binding activity and GTPase activator activity. Involved in several processes, including G protein-coupled acetylcholine receptor signaling pathway; positive regulation of GTPase activity; and response to amphetamine. Located in several cellular components, including cytoplasmic side of plasma membrane; dendrite; and neuronal cell body membrane. Orthologous to human RGS8 (regulator of G protein signaling 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
MGC105444
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
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Orthologs 1
Homo sapiens (human):
RGS8 (regulator of G protein signaling 8)
HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Rgs8 (regulator of G-protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Rgs8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
RGS8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
RGS8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Rgs8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
RGS8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
RGS8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Rgs8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Rgs8 (regulator of G protein signaling 8)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
EPHX1 (epoxide hydrolase 1)
HGNC
OMA
Homo sapiens (human):
DISP1 (dispatched RND transporter family member 1)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
RGS8 (regulator of G protein signaling 8)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Rgs8 (regulator of G-protein signaling 8)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
rgs8 (regulator of G protein signaling 8)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
rgs-10
Alliance
DIOPT (OrthoFinder|PANTHER)
Caenorhabditis elegans (roundworm):
rgs-10
Alliance
DIOPT (OrthoFinder|PANTHER|PhylomeDB)
Caenorhabditis elegans (roundworm):
rgs-11
Alliance
DIOPT (OrthoFinder|PANTHER)
Caenorhabditis elegans (roundworm):
rgs-7
Alliance
DIOPT (OrthoFinder|PANTHER)
Xenopus tropicalis (tropical clawed frog):
rgs16
Alliance
DIOPT (OMA|OrthoFinder|PANTHER)
Saccharomyces cerevisiae (baker's yeast):
SST2
Alliance
DIOPT (OrthoFinder|PANTHER)
Xenopus tropicalis (tropical clawed frog):
rgs8
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 13 68,355,078 - 68,399,412 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 13 68,355,157 - 68,399,412 (+) Ensembl GRCr8 mRatBN7.2 13 65,804,703 - 65,848,955 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 13 65,804,797 - 65,846,807 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 13 68,417,809 - 68,450,067 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 13 69,707,795 - 69,740,068 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 13 66,960,758 - 66,993,076 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 13 71,086,654 - 71,141,820 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 13 71,086,745 - 71,141,075 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 13 76,051,812 - 76,105,170 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 13 68,735,814 - 68,766,956 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 13 65,717,445 - 65,747,668 (+) NCBI Celera RGSC_v3.1 13 68,749,893 - 68,781,036 (+) NCBI Cytogenetic Map 13 q21 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Rgs8 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Rgs8 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rgs8 Rat 1,2-dimethylhydrazine decreases expression ISO Rgs8 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of RGS8 mRNA CTD PMID:22206623 Rgs8 Rat 17beta-estradiol decreases expression ISO Rgs8 (Mus musculus) 6480464 Estradiol results in decreased expression of RGS8 mRNA CTD PMID:26879975 Rgs8 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Rgs8 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rgs8 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Rgs8 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rgs8 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of RGS8 mRNA CTD PMID:19692669 Rgs8 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Rgs8 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rgs8 Rat 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RGS8 mRNA CTD PMID:19692669 Rgs8 Rat 4,4'-sulfonyldiphenol decreases expression ISO Rgs8 (Mus musculus) 6480464 bisphenol S results in decreased expression of RGS8 mRNA CTD PMID:30951980 Rgs8 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of RGS8 mRNA CTD PMID:24780913 Rgs8 Rat acetamide decreases expression EXP 6480464 acetamide results in decreased expression of RGS8 mRNA CTD PMID:31881176 Rgs8 Rat aflatoxin B1 increases methylation ISO RGS8 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of RGS8 gene CTD PMID:27153756 Rgs8 Rat Aflatoxin B2 alpha increases methylation ISO RGS8 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of RGS8 3' UTR CTD PMID:30157460 Rgs8 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of RGS8 mRNA CTD PMID:16483693 Rgs8 Rat arsane affects methylation ISO RGS8 (Homo sapiens) 6480464 Arsenic affects the methylation of RGS8 gene CTD PMID:25304211 Rgs8 Rat arsenic atom affects methylation ISO RGS8 (Homo sapiens) 6480464 Arsenic affects the methylation of RGS8 gene CTD PMID:25304211 Rgs8 Rat atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of RGS8 mRNA CTD PMID:36841081 Rgs8 Rat atrazine affects methylation EXP 6480464 Atrazine affects the methylation of RGS8 gene CTD PMID:35440735 Rgs8 Rat benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of RGS8 mRNA CTD PMID:21839799 Rgs8 Rat benzo[a]pyrene decreases methylation ISO Rgs8 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of RGS8 intron CTD PMID:27901495 Rgs8 Rat bis(2-ethylhexyl) phthalate increases expression ISO Rgs8 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of RGS8 mRNA CTD PMID:28085963 Rgs8 Rat bis(2-ethylhexyl) phthalate decreases expression ISO RGS8 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased expression of RGS8 mRNA CTD PMID:31163220 Rgs8 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of RGS8 mRNA CTD PMID:25181051 Rgs8 Rat bisphenol A decreases expression ISO Rgs8 (Mus musculus) 6480464 bisphenol A results in decreased expression of RGS8 mRNA CTD PMID:32156529 Rgs8 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of RGS8 mRNA CTD PMID:34947998|PMID:38750585 Rgs8 Rat bisphenol F decreases expression ISO Rgs8 (Mus musculus) 6480464 bisphenol F results in decreased expression of RGS8 mRNA CTD PMID:30951980 Rgs8 Rat clozapine increases expression EXP 6480464 Clozapine results in increased expression of RGS8 mRNA CTD PMID:15860345 Rgs8 Rat coumarin decreases expression EXP 6480464 coumarin results in decreased expression of RGS8 mRNA CTD PMID:18480146 Rgs8 Rat crocidolite asbestos affects methylation ISO RGS8 (Homo sapiens) 6480464 Asbestos, Crocidolite affects the methylation of RGS8 gene CTD PMID:29523930 Rgs8 Rat fenvalerate increases expression EXP 6480464 fenvalerate results in increased expression of RGS8 mRNA CTD PMID:30307764 Rgs8 Rat flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of RGS8 mRNA CTD PMID:18035473 Rgs8 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of RGS8 mRNA CTD PMID:33387578 Rgs8 Rat haloperidol increases expression EXP 6480464 Haloperidol results in increased expression of RGS8 mRNA CTD PMID:15860345 Rgs8 Rat L-ascorbic acid decreases expression EXP 6480464 Ascorbic Acid results in decreased expression of RGS8 mRNA CTD PMID:15372504 Rgs8 Rat niclosamide decreases expression ISO RGS8 (Homo sapiens) 6480464 Niclosamide results in decreased expression of RGS8 mRNA CTD PMID:36318118 Rgs8 Rat nitroglycerin increases expression EXP 6480464 Nitroglycerin results in increased expression of RGS8 mRNA CTD PMID:12102619 Rgs8 Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of RGS8 mRNA CTD PMID:30723492 Rgs8 Rat PCB138 multiple interactions ISO Rgs8 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Rgs8 Rat perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of RGS8 mRNA CTD PMID:16221955|PMID:19162173 Rgs8 Rat reserpine decreases expression EXP 6480464 Reserpine results in decreased expression of RGS8 mRNA CTD PMID:14505795 Rgs8 Rat silicon dioxide decreases expression ISO RGS8 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of RGS8 mRNA CTD PMID:25895662 Rgs8 Rat sodium arsenite decreases expression ISO Rgs8 (Mus musculus) 6480464 sodium arsenite results in decreased expression of RGS8 mRNA CTD PMID:37682722 Rgs8 Rat sodium fluoride decreases expression ISO Rgs8 (Mus musculus) 6480464 Sodium Fluoride results in decreased expression of RGS8 mRNA CTD PMID:21340527 Rgs8 Rat tipifarnib increases expression EXP 6480464 tipifarnib results in increased expression of RGS8 mRNA CTD PMID:16403772 Rgs8 Rat trimellitic anhydride increases expression ISO Rgs8 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of RGS8 mRNA CTD PMID:19042947 Rgs8 Rat triptonide increases expression ISO Rgs8 (Mus musculus) 6480464 triptonide results in increased expression of RGS8 mRNA CTD PMID:33045310