Art2b (ADP-ribosyltransferase 2b) - Rat Genome Database

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Pathways
Gene: Art2b (ADP-ribosyltransferase 2b) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Art2b
Name: ADP-ribosyltransferase 2b
RGD ID: 3521
Description: Predicted to enable NAD+ poly-ADP-ribosyltransferase activity; NAD+-protein-arginine ADP-ribosyltransferase activity; and hydrolase activity, acting on glycosyl bonds. Predicted to be involved in NAD+ catabolic process. Predicted to be located in external side of plasma membrane; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosyltransferase 2; ADP-ribosyltransferase 2a; ADP-ribosyltransferase C2 and C3 toxin-like 2; Ag-F; alloantigen Rt6.1; alloantigen Rt6.2; Art2; ART2a; ARTC2; cell surface alloantigen 6; cell surface alloantigen 6 (mapped); Cell surface alloantigen peripheral T-cell antigen; Cell surface alloantigen, peripheral T-cell antigen; Ly-2; LY2; MGC116041; mono(ADP-ribosyl)transferase 2A; mono(ADP-ribosyl)transferase 2B; NAD(+) glycohydrolase; PtaA; Rt6; RT6.1; RT6.2; Rt6_mapped; T cell differentiation marker RT6.1; T-cell ecto-ADP-ribosyltransferase 1; T-cell ecto-ADP-ribosyltransferase 2; T-cell mono(ADP-ribosyl)transferase 1; T-cell mono(ADP-ribosyl)transferase 2; T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 1; T-cell NAD(P)(+)--arginine ADP-ribosyltransferase 2; T-cell surface protein Rt6.1; T-cell surface protein Rt6.2
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81165,368,623 - 165,386,280 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1165,368,625 - 165,378,345 (-)EnsemblGRCr8
mRatBN7.21155,956,601 - 155,974,252 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1155,956,603 - 155,974,253 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1163,939,314 - 163,942,753 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01171,119,394 - 171,122,831 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01164,005,593 - 164,008,909 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01166,665,029 - 166,685,097 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1166,667,169 - 166,677,026 (-)Ensemblrn6Rnor6.0
Rnor_5.01172,857,747 - 172,875,530 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41159,055,461 - 159,058,780 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1154,035,229 - 154,038,548 (-)NCBICelera
RGSC_v3.11159,134,604 - 159,137,780 (-)NCBI
Cytogenetic Map1q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Regulatory role of arginine 204 in the catalytic activity of rat alloantigens ART2a and ART2b. Stevens LA, etal., J Biol Chem 2003 May 30;278(22):19591-6. Epub 2003 Mar 20.
Additional References at PubMed
PMID:2129547   PMID:2300588   PMID:2632369   PMID:8144525   PMID:8690084   PMID:8757323   PMID:12077446   PMID:12187378   PMID:12270706   PMID:12477932   PMID:16931513  


Genomics

Variants

.
Variants in Art2b
174 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:264
Count of miRNA genes:182
Interacting mature miRNAs:200
Transcripts:ENSRNOT00000026644
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889419Cstrr2Cold stress response QTL 20.05urine catecholamine amount (VT:0010502)absolute change in urine norepinephrine level (CMO:0001634)1165278545168003898Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1131179947176179947Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1160111531262090437Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753266453731Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)1137611478182611478Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1153679879198679879Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1132760429191848948Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1153679879205813246Rat
8694166Bw147Body weight QTL 1476.830.001body mass (VT:0001259)body weight gain (CMO:0000420)1153788989198788989Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1142582336182383862Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1160573753210707719Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1162548015270518180Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1132966869252856240Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1139442053223964440Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1152919152268496042Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1160573753210707719Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1165278545210278545Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1160111531262090437Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1161077990206077990Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1159894717207261263Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1163992710208992710Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1146080545243492863Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1141173126169168317Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1155359438194575574Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1140833106185833106Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1153679879232414077Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1160574007235238518Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1131243790176243790Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1160111426262090599Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1129182274174182274Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1132760429191848948Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1154961463266453731Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1162753891207753891Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1153680016182383862Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1153680016183564652Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1128019551173019551Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1139442053223964440Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1143092939188092939Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436178317588Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1160573753266453731Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1140048073185048073Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1160573753210707719Rat
8693608Alc24Alcohol consumption QTL 242.30.74drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1159863716177663210Rat
1576310Schws2Schwannoma susceptibility QTL 20.029nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)1153788989198788989Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1135021436180021436Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1132760429191190115Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1132966869206393015Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1140915717185915717Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1132760429191848948Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat
7411599Foco11Food consumption QTL 1118.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)1153788989198788989Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1160573753210707719Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 28 56 81 80 49 92 49 6 280 146 5 34 62 55 31 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_198735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008759702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063285196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC122631 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ297708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY050216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M85193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X52082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X99124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000026644   ⟹   ENSRNOP00000026644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1165,368,625 - 165,378,345 (-)Ensembl
mRatBN7.2 Ensembl1155,956,603 - 155,966,317 (-)Ensembl
Rnor_6.0 Ensembl1166,667,304 - 166,677,026 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1166,669,811 - 166,677,026 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076714   ⟹   ENSRNOP00000068409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1166,669,811 - 166,677,026 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087792   ⟹   ENSRNOP00000069125
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1165,368,625 - 165,372,191 (-)Ensembl
mRatBN7.2 Ensembl1155,956,603 - 155,974,253 (-)Ensembl
Rnor_6.0 Ensembl1166,667,169 - 166,670,867 (-)Ensembl
RefSeq Acc Id: NM_198735   ⟹   NP_942030
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81165,368,639 - 165,371,958 (-)NCBI
mRatBN7.21155,956,617 - 155,959,936 (-)NCBI
Rnor_6.01166,667,320 - 166,670,639 (-)NCBI
Rnor_5.01172,857,747 - 172,875,530 (-)NCBI
RGSC_v3.41159,055,461 - 159,058,780 (-)RGD
Celera1154,035,229 - 154,038,548 (-)RGD
Sequence:
RefSeq Acc Id: XM_017588959   ⟹   XP_017444448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81165,368,623 - 165,386,263 (-)NCBI
mRatBN7.21155,956,601 - 155,974,252 (-)NCBI
Rnor_6.01166,667,304 - 166,677,292 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106113   ⟹   XP_038962041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81165,368,623 - 165,386,257 (-)NCBI
mRatBN7.21155,956,601 - 155,974,252 (-)NCBI
RefSeq Acc Id: XM_063285189   ⟹   XP_063141259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81165,368,623 - 165,386,280 (-)NCBI
RefSeq Acc Id: XM_063285194   ⟹   XP_063141264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81165,368,623 - 165,379,228 (-)NCBI
RefSeq Acc Id: XM_063285196   ⟹   XP_063141266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81165,368,623 - 165,379,228 (-)NCBI
RefSeq Acc Id: NP_942030   ⟸   NM_198735
- Peptide Label: precursor
- UniProtKB: Q9EPH9 (UniProtKB/Swiss-Prot),   Q95576 (UniProtKB/Swiss-Prot),   Q4FZV8 (UniProtKB/Swiss-Prot),   P97912 (UniProtKB/Swiss-Prot),   P20974 (UniProtKB/Swiss-Prot),   P17982 (UniProtKB/Swiss-Prot),   A6I6V2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444448   ⟸   XM_017588959
- Peptide Label: isoform X2
- UniProtKB: Q9EPH9 (UniProtKB/Swiss-Prot),   Q95576 (UniProtKB/Swiss-Prot),   Q4FZV8 (UniProtKB/Swiss-Prot),   P97912 (UniProtKB/Swiss-Prot),   P20974 (UniProtKB/Swiss-Prot),   P17982 (UniProtKB/Swiss-Prot),   A6I6V2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069125   ⟸   ENSRNOT00000087792
Ensembl Acc Id: ENSRNOP00000026644   ⟸   ENSRNOT00000026644
Ensembl Acc Id: ENSRNOP00000068409   ⟸   ENSRNOT00000076714
RefSeq Acc Id: XP_038962041   ⟸   XM_039106113
- Peptide Label: isoform X2
- UniProtKB: Q9EPH9 (UniProtKB/Swiss-Prot),   Q95576 (UniProtKB/Swiss-Prot),   Q4FZV8 (UniProtKB/Swiss-Prot),   P97912 (UniProtKB/Swiss-Prot),   P20974 (UniProtKB/Swiss-Prot),   P17982 (UniProtKB/Swiss-Prot),   A6I6V2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141259   ⟸   XM_063285189
- Peptide Label: isoform X1
- UniProtKB: P17982 (UniProtKB/Swiss-Prot),   A0A0G2JUJ8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141266   ⟸   XM_063285196
- Peptide Label: isoform X2
- UniProtKB: P17982 (UniProtKB/Swiss-Prot),   Q9EPH9 (UniProtKB/Swiss-Prot),   Q95576 (UniProtKB/Swiss-Prot),   Q4FZV8 (UniProtKB/Swiss-Prot),   P97912 (UniProtKB/Swiss-Prot),   P20974 (UniProtKB/Swiss-Prot),   A6I6V2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141264   ⟸   XM_063285194
- Peptide Label: isoform X2
- UniProtKB: P17982 (UniProtKB/Swiss-Prot),   Q9EPH9 (UniProtKB/Swiss-Prot),   Q95576 (UniProtKB/Swiss-Prot),   Q4FZV8 (UniProtKB/Swiss-Prot),   P97912 (UniProtKB/Swiss-Prot),   P20974 (UniProtKB/Swiss-Prot),   A6I6V2 (UniProtKB/TrEMBL)
Protein Domains
TR mART core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P17982-F1-model_v2 AlphaFold P17982 1-275 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690257
Promoter ID:EPDNEW_R782
Type:single initiation site
Name:Art2b_1
Description:ADP-ribosyltransferase 2b
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01166,677,025 - 166,677,085EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3521 AgrOrtholog
BioCyc Gene G2FUF-58282 BioCyc
Ensembl Genes ENSRNOG00000019687 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000026644.9 UniProtKB/Swiss-Prot
  ENSRNOT00000087792 ENTREZGENE
Gene3D-CATH Toxin ADP-ribosyltransferase, Chain A, domain 1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7366134 IMAGE-MGC_LOAD
InterPro ADP-ribosyltransferase_ARG UniProtKB/Swiss-Prot
  ART UniProtKB/Swiss-Prot
KEGG Report rno:293152 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116041 IMAGE-MGC_LOAD
NCBI Gene Art2b ENTREZGENE
PANTHER ADP-RIBOSYLTRANSFERASE UniProtKB/Swiss-Prot
  T-CELL ECTO-ADP-RIBOSYLTRANSFERASE 1-RELATED UniProtKB/Swiss-Prot
Pfam ART UniProtKB/Swiss-Prot
PhenoGen Art2b PhenoGen
PRINTS RIBTRNSFRASE UniProtKB/Swiss-Prot
PROSITE ART UniProtKB/Swiss-Prot
  TR_MART UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019687 RatGTEx
Superfamily-SCOP ADP-ribosylation UniProtKB/Swiss-Prot
UniProt A0A0G2JUJ8 ENTREZGENE, UniProtKB/TrEMBL
  A6I6V2 ENTREZGENE, UniProtKB/TrEMBL
  NAR2A_RAT UniProtKB/Swiss-Prot
  NAR2B_RAT UniProtKB/Swiss-Prot
  P17982 ENTREZGENE
  P20974 ENTREZGENE
  P97912 ENTREZGENE
  Q4FZV8 ENTREZGENE
  Q95576 ENTREZGENE
  Q9EPH9 ENTREZGENE
UniProt Secondary P97912 UniProtKB/Swiss-Prot
  Q4FZV8 UniProtKB/Swiss-Prot
  Q95576 UniProtKB/Swiss-Prot
  Q9EPH9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-22 Art2b  ADP-ribosyltransferase 2b  Art2  ADP-ribosyltransferase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-05-15 Art2b  adenylate cyclase activating polypeptide 1 receptor 1  ART2b  ADP-ribosyltransferase 2b  Symbol updated 1299863 APPROVED
2008-04-25 ART2b  ADP-ribosyltransferase 2b  Rt6_mapped  cell surface alloantigen 6 (mapped)  Symbol and Name updated 1299863 APPROVED
2008-04-25 Rt6_mapped  cell surface alloantigen 6 (mapped)  Art2b  ADP-ribosyltransferase 2b  Data merged from RGD:735218 737654 APPROVED
2005-11-17 Rt6_mapped  cell surface alloantigen 6 (mapped)      Symbol and Name updated 1556543 APPROVED
2004-09-10 Art2b  ADP-ribosyltransferase 2b  RT6.2  RT6.2 protein  Symbol and Name updated 1299863 APPROVED
2003-04-09 Rt6  cell surface alloantigen 6  RT6  Cell surface alloantigen, peripheral T-cell antigen  Name updated 629478 APPROVED
2002-06-10 RT6  Cell surface alloantigen, peripheral T-cell antigen      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression protein is detected on post-thymic peripheral and intestinal intraepithelial T lymphocytes only 1298626
gene_function allele ART2b, but not ART2a, has auto-ADP-ribosylation activity 1298626
gene_protein ART2a and ART2b are allelic forms; only allele ART2a is glycosylated 1298626