Pgam2 (phosphoglycerate mutase 2) - Rat Genome Database

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Gene: Pgam2 (phosphoglycerate mutase 2) Rattus norvegicus
Analyze
Symbol: Pgam2
Name: phosphoglycerate mutase 2
RGD ID: 3313
Description: Enables phosphoglycerate mutase activity. Involved in gluconeogenesis; response to mercury ion; and spermatogenesis. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in myoglobinuria. Orthologous to human PGAM2 (phosphoglycerate mutase 2); PARTICIPATES IN gluconeogenesis pathway; Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BPG-dependent PGAM 2; D14Mgh1; isozyme MM; muscle-specific phosphoglycerate mutase; PGAM-M; Pgmut; phosphoglycerate mutase 2 (muscle); phosphoglycerate mutase isozyme M; type MM phosphoglycerate mutase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,895,763 - 84,897,874 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,895,744 - 84,897,894 (-)EnsemblGRCr8
mRatBN7.21480,681,796 - 80,683,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,681,776 - 80,683,940 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,084,326 - 85,086,436 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,324,429 - 86,326,539 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,773,751 - 82,775,861 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,045,005 - 86,047,116 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,736,814 - 86,738,925 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,466,055 - 86,468,166 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,566,749 - 79,568,860 (-)NCBICelera
RGSC_v3.11486,485,199 - 86,487,311 (-)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-diaminotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acrylamide  (EXP)
aldehydo-D-glucose  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
aristolochic acids  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cantharidin  (ISO)
carbon nanotube  (ISO)
ciguatoxin CTX1B  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
D-glucose  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
fenvalerate  (EXP)
genistein  (EXP,ISO)
glucose  (ISO)
glyphosate  (ISO)
graphite  (ISO)
hydralazine  (ISO)
hydrogen sulfide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (EXP)
iron dichloride  (ISO)
Monobutylphthalate  (ISO)
N(4)-hydroxycytidine  (ISO)
ochratoxin A  (EXP)
ozone  (EXP)
paracetamol  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
picrotoxin  (EXP)
pioglitazone  (ISO)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfasalazine  (ISO)
sunitinib  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
triclosan  (ISO)
Triptolide  (EXP)
triptonide  (ISO)
triticonazole  (EXP)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IDA)
ooplasm  (IDA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The muscle-specific phosphoglycerate mutase gene is specifically expressed in testis during spermatogenesis. Broceno C, etal., Eur J Biochem. 1995 Feb 1;227(3):629-35.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Inactivation of type MM phosphoglycerate mutase by sulfhydryl group reagents during facial embryogenesis. Granstrom G and Mangs H, Acta Odontol Scand. 1988 Oct;46(5):273-9.
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. The histidine phosphatase superfamily: structure and function. Rigden DJ Biochem J. 2008 Jan 15;409(2):333-48.
13. The gene encoding rat phosphoglycerate mutase subunit M: cloning and promoter analysis in skeletal muscle cells. Ruiz-Lozano P, etal., Gene 1994 Sep 30;147(2):243-8.
14. Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase. Sakai A, etal., Chem Res Toxicol. 2005 Feb;18(2):277-82.
15. Gene-based anchoring of the rat genetic linkage and cytogenetic maps: new regional localizations, orientation of the linkage groups, and insights into mammalian chromosome evolution. Szpirer C, etal., Mamm Genome 1998 Sep;9(9):721-34
16. The molecular genetic basis of muscle phosphoglycerate mutase (PGAM) deficiency. Tsujino S, etal., Am J Hum Genet. 1993 Mar;52(3):472-7.
17. Location of phosphoglycerate mutase in rat skeletal muscle. An immunocytochemical and biochemical study. Urena JM, etal., Eur J Cell Biol. 1990 Feb;51(1):151-6.
Additional References at PubMed
PMID:2558656   PMID:2824255   PMID:4827367   PMID:6262916   PMID:11250083   PMID:15665293   PMID:21630459   PMID:23117660   PMID:23533145   PMID:29476059  


Genomics

Comparative Map Data
Pgam2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,895,763 - 84,897,874 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1484,895,744 - 84,897,894 (-)EnsemblGRCr8
mRatBN7.21480,681,796 - 80,683,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,681,776 - 80,683,940 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1485,084,326 - 85,086,436 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,324,429 - 86,326,539 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,773,751 - 82,775,861 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01486,045,005 - 86,047,116 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01486,736,814 - 86,738,925 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41486,466,055 - 86,468,166 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1479,566,749 - 79,568,860 (-)NCBICelera
RGSC_v3.11486,485,199 - 86,487,311 (-)NCBI
Cytogenetic Map14q21NCBI
PGAM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38744,062,727 - 44,065,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl744,062,727 - 44,065,605 (-)Ensemblhg38GRCh38
GRCh37744,102,326 - 44,105,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36744,068,851 - 44,071,688 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34743,875,566 - 43,878,403NCBI
Celera744,200,271 - 44,203,131 (-)NCBICelera
Cytogenetic Map7p13NCBI
HuRef743,987,609 - 43,990,469 (-)NCBIHuRef
CHM1_1744,106,200 - 44,109,060 (-)NCBICHM1_1
T2T-CHM13v2.0744,221,224 - 44,224,064 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2744,141,816 - 44,144,674 (-)NCBI
Pgam2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,751,637 - 5,753,796 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,751,640 - 5,753,733 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38115,801,637 - 5,803,796 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,801,640 - 5,803,733 (-)Ensemblmm10GRCm38
MGSCv37115,701,640 - 5,703,799 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36115,701,647 - 5,703,736 (-)NCBIMGSCv36mm8
Celera116,291,798 - 6,293,956 (-)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.87NCBI
Pgam2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554567,909,891 - 7,912,116 (+)Ensembl
ChiLan1.0NW_0049554567,909,891 - 7,912,116 (+)NCBIChiLan1.0ChiLan1.0
PGAM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2648,973,896 - 48,983,253 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1797,297,291 - 97,301,591 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0744,776,722 - 44,780,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1744,843,067 - 44,846,274 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl744,843,067 - 44,845,984 (-)EnsemblpanPan2panpan1.1
PGAM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_Tasha162,007,972 - 2,010,428 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01614,851,571 - 14,854,027 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1614,851,574 - 14,854,031 (+)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.01614,482,753 - 14,485,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01614,463,237 - 14,465,693 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pgam2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511899,810,197 - 99,812,642 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647819,020,048 - 19,024,394 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647819,021,928 - 19,026,110 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGAM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1848,710,347 - 48,713,862 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11848,693,832 - 48,712,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21853,423,580 - 53,425,838 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PGAM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12114,604,127 - 14,609,196 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2114,606,401 - 14,609,158 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660627,905,467 - 7,908,316 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgam2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247407,947,742 - 7,950,956 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247407,947,738 - 7,949,900 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Pgam2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11174,762,132 - 74,764,271 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pgam2
24 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:42
Interacting mature miRNAs:43
Transcripts:ENSRNOT00000018227
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
D14Mgh1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81484,898,800 - 84,898,905 (+)Marker Load Pipeline
mRatBN7.21480,684,833 - 80,684,938 (+)MAPPERmRatBN7.2
Rnor_6.01486,048,043 - 86,048,147NCBIRnor6.0
Rnor_5.01486,739,852 - 86,739,956UniSTSRnor5.0
RGSC_v3.41486,469,093 - 86,469,197UniSTSRGSC3.4
Celera1479,569,638 - 79,569,742UniSTS
RH 3.4 Map14571.5RGD
RH 3.4 Map14571.5UniSTS
RH 2.0 Map14702.9RGD
SHRSP x BN Map1444.8999RGD
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
D14Rat19  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81484,898,287 - 84,898,449 (+)Marker Load Pipeline
mRatBN7.21480,684,320 - 80,684,482 (+)MAPPERmRatBN7.2
Rnor_6.01486,047,530 - 86,047,691NCBIRnor6.0
Rnor_5.01486,739,339 - 86,739,500UniSTSRnor5.0
RGSC_v3.41486,468,580 - 86,468,741UniSTSRGSC3.4
RGSC_v3.41486,468,542 - 86,468,937RGDRGSC3.4
RGSC_v3.11486,487,725 - 86,487,886RGD
RH 3.4 Map14571.5RGD
RH 3.4 Map14571.5UniSTS
RH 2.0 Map14702.7RGD
SHRSP x BN Map1445.38RGD
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS
AW527377  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21480,682,949 - 80,683,113 (+)MAPPERmRatBN7.2
Rnor_6.01486,046,159 - 86,046,322NCBIRnor6.0
Rnor_5.01486,737,968 - 86,738,131UniSTSRnor5.0
RGSC_v3.41486,467,209 - 86,467,372UniSTSRGSC3.4
Celera1479,567,903 - 79,568,066UniSTS
RH 3.4 Map14571.5UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map14q21-q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 12 67 108 66 65 34 87 34 6 324 187 11 87 81 87 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_017328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214696 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH770049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HH770393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M31835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z17319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000018227   ⟹   ENSRNOP00000018227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1484,895,744 - 84,897,894 (-)Ensembl
mRatBN7.2 Ensembl1480,681,776 - 80,683,940 (-)Ensembl
Rnor_6.0 Ensembl1486,044,969 - 86,047,162 (-)Ensembl
RefSeq Acc Id: NM_017328   ⟹   NP_059024
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81484,895,763 - 84,897,874 (-)NCBI
mRatBN7.21480,681,796 - 80,683,907 (-)NCBI
Rnor_6.01486,045,005 - 86,047,116 (-)NCBI
Rnor_5.01486,736,814 - 86,738,925 (-)NCBI
RGSC_v3.41486,466,055 - 86,468,166 (-)RGD
Celera1479,566,749 - 79,568,860 (-)RGD
Sequence:
RefSeq Acc Id: NP_059024   ⟸   NM_017328
- UniProtKB: P16290 (UniProtKB/Swiss-Prot),   A6IKP7 (UniProtKB/TrEMBL),   A6IKP6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018227   ⟸   ENSRNOT00000018227

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16290-F1-model_v2 AlphaFold P16290 1-253 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699462
Promoter ID:EPDNEW_R9986
Type:initiation region
Name:Pgam2_1
Description:phosphoglycerate mutase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01486,047,132 - 86,047,192EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3313 AgrOrtholog
BioCyc Gene G2FUF-15126 BioCyc
BioCyc Pathway ANAGLYCOLYSIS-PWY [glycolysis III (from glucose)] BioCyc
  PWY-6405 [Rapoport-Luebering glycolytic shunt] BioCyc
  PWY66-399 [gluconeogenesis III] BioCyc
BioCyc Pathway Image ANAGLYCOLYSIS-PWY BioCyc
  PWY-6405 BioCyc
  PWY66-399 BioCyc
Ensembl Genes ENSRNOG00000013532 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000018227 ENTREZGENE
  ENSRNOT00000018227.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1240 UniProtKB/Swiss-Prot
InterPro His_Pase_superF_clade-1 UniProtKB/Swiss-Prot
  His_PPase_superfam UniProtKB/Swiss-Prot
  PG/BPGM_mutase_AS UniProtKB/Swiss-Prot
  Phosphogly_mut1 UniProtKB/Swiss-Prot
KEGG Report rno:24959 UniProtKB/Swiss-Prot
NCBI Gene 24959 ENTREZGENE
PANTHER PTHR11931 UniProtKB/Swiss-Prot
Pfam His_Phos_1 UniProtKB/Swiss-Prot
PhenoGen Pgam2 PhenoGen
PIRSF 6PFK_2-Ptase UniProtKB/Swiss-Prot
PROSITE PG_MUTASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013532 RatGTEx
SMART PGAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53254 UniProtKB/Swiss-Prot
UniProt A6IKP6 ENTREZGENE, UniProtKB/TrEMBL
  A6IKP7 ENTREZGENE, UniProtKB/TrEMBL
  A6IKP8_RAT UniProtKB/TrEMBL
  P16290 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Pgam2  phosphoglycerate mutase 2  Pgam2  phosphoglycerate mutase 2 (muscle)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Pgam2  phosphoglycerate mutase 2 (muscle)  Pgam2  phosphoglycerate mutase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pgam2  phosphoglycerate mutase 2      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function interconverts 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction