Pgam1 (phosphoglycerate mutase 1) - Rat Genome Database

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Gene: Pgam1 (phosphoglycerate mutase 1) Rattus norvegicus
Analyze
Symbol: Pgam1
Name: phosphoglycerate mutase 1
RGD ID: 3312
Description: Enables phosphoglycerate mutase activity. Predicted to be involved in canonical glycolysis and gluconeogenesis. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to several human genes including PGAM1 (phosphoglycerate mutase 1); PARTICIPATES IN Fanconi syndrome pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BPG-dependent PGAM 1; PGAM-B; Pgmut; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase 1 reserved symbol; phosphoglycerate mutase isozyme B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81250,673,152 - 250,680,762 (+)NCBIGRCr8
mRatBN7.21240,723,832 - 240,731,443 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1240,723,920 - 240,738,452 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1248,868,982 - 248,876,729 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01255,566,135 - 255,573,881 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01248,219,147 - 248,226,892 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01261,158,204 - 261,165,814 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1261,158,261 - 261,165,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01268,610,733 - 268,618,280 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1236,559,231 - 236,566,463 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgam1Ratadenocarcinoma  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15378696
Pgam1RatAnimal Mammary Neoplasms  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Pgam1Ratcarcinoma  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Pgam1RatExperimental Mammary Neoplasms  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Pgam1Ratlung non-small cell carcinoma  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17094902
Pgam1RatMouth Neoplasms  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15274141
Pgam1Ratsquamous cell carcinoma  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15274141
Pgam1RatStomach Neoplasms  ISOPGAM1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:15378696

1 to 20 of 182 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgam1Rat(1->4)-beta-D-glucan multiple interactionsISOPgam1 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PGAM1 mRNACTDPMID:36331819
Pgam1Rat1,2-dimethylhydrazine decreases expressionISOPgam1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PGAM1 mRNACTDPMID:22206623
Pgam1Rat1,2-dimethylhydrazine multiple interactionsISOPgam1 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PGAM1 mRNACTDPMID:22206623
Pgam1Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of PGAM1 mRNACTDPMID:32145629
Pgam1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOPGAM1 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in decreased expression of PGAM1 mRNACTDPMID:21802500
Pgam1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PGAM1 mRNACTDPMID:32109520 more ...
Pgam1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PGAM1 proteinCTDPMID:15822908
Pgam1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPgam1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PGAM1 mRNACTDPMID:21570461
Pgam1Rat2,5-hexanedione increases expressionEXP 64804642 and 5-hexanedione results in increased expression of PGAM1 proteinCTDPMID:19033394
Pgam1Rat2-methylcholine affects expressionISOPGAM1 (Homo sapiens)6480464beta-methylcholine affects the expression of PGAM1 mRNACTDPMID:21179406
Pgam1Rat3H-1,2-dithiole-3-thione increases expressionEXP 64804641 and 2-dithiol-3-thione results in increased expression of PGAM1 mRNACTDPMID:19162173
Pgam1Rat4,4'-sulfonyldiphenol increases expressionISOPgam1 (Mus musculus)6480464bisphenol S results in increased expression of PGAM1 mRNACTDPMID:39298647
Pgam1Rat4,4'-sulfonyldiphenol increases expressionISOPGAM1 (Homo sapiens)6480464bisphenol S results in increased expression of PGAM1 proteinCTDPMID:34186270
Pgam1Rat5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expressionEXP 6480464Omeprazole affects the expression of PGAM1 mRNACTDPMID:19483382
Pgam1Rat6-propyl-2-thiouracil affects expressionEXP 6480464Propylthiouracil affects the expression of PGAM1 mRNACTDPMID:19483382
Pgam1Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PGAM1 mRNACTDPMID:30047161
Pgam1Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PGAM1 mRNACTDPMID:24780913
Pgam1Ratactinomycin D multiple interactionsISOPGAM1 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of PGAM1 proteinCTDPMID:38460933
Pgam1Ratall-trans-retinoic acid increases expressionISOPGAM1 (Homo sapiens)6480464Tretinoin results in increased expression of PGAM1 mRNACTDPMID:33167477
Pgam1Ratamiodarone affects expressionEXP 6480464Amiodarone affects the expression of PGAM1 mRNACTDPMID:19483382

1 to 20 of 182 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgam1Ratcanonical glycolysis involved_inISOPGAM1 (Homo sapiens)1624291 PMID:12189148RGDPMID:12189148
Pgam1Ratgluconeogenesis involved_inISOPgam1 (Mus musculus)1624291 PMID:24958256RGDPMID:24958256
Pgam1Ratglycolytic process involved_inIEAInterPro:IPR0059521600115GO_REF:0000002InterProGO_REF:0000002
Pgam1Ratglycolytic process involved_inIEAUniProtKB-KW:KW-03241600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  

Molecular Function
1 to 17 of 17 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgam1Ratbisphosphoglycerate mutase activity enablesISSUniProtKB:P186691600115GO_REF:0000024UniProtGO_REF:0000024
Pgam1Ratbisphosphoglycerate mutase activity enablesIEAEC:5.4.2.41600115GO_REF:0000003UniProtGO_REF:0000003
Pgam1Ratbisphosphoglycerate mutase activity enablesIEARHEA:177651600115GO_REF:0000116RHEAGO_REF:0000116
Pgam1Ratbisphosphoglycerate mutase activity enablesISOPGAM1 (Homo sapiens)1624291 PMID:23653202RGDPMID:23653202
Pgam1Ratcatalytic activity enablesIEAInterPro:IPR0013451600115GO_REF:0000002InterProGO_REF:0000002
Pgam1Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Pgam1Ratintramolecular phosphotransferase activity enablesIEAInterPro:IPR0059521600115GO_REF:0000002InterProGO_REF:0000002
Pgam1Ratintramolecular phosphotransferase activity enablesIEAARBA:ARBA000269591600115GO_REF:0000117UniProtGO_REF:0000117
Pgam1Ratisomerase activity enablesIEAUniProtKB-KW:KW-04131600115GO_REF:0000043UniProtGO_REF:0000043
Pgam1Ratphosphoglycerate mutase activity  IDA 2302785 RGD 
Pgam1Ratphosphoglycerate mutase activity enablesIEAEC:5.4.2.111600115GO_REF:0000003UniProtGO_REF:0000003
Pgam1Ratphosphoglycerate mutase activity enablesISOPgam1 (Mus musculus)1624291 PMID:11250083 and PMID:2824255RGDMGI:52934 more ...
Pgam1Ratphosphoglycerate mutase activity enablesISOPGAM1 (Homo sapiens)1624291 PMID:12189148 more ...RGDPMID:12189148 more ...
Pgam1Ratphosphoglycerate mutase activity enablesISSUniProtKB:P186691600115GO_REF:0000024UniProtGO_REF:0000024
Pgam1Ratphosphoglycerate mutase activity enablesIEARHEA:159011600115GO_REF:0000116RHEAGO_REF:0000116
Pgam1Ratprotein binding enablesISOPGAM1 (Homo sapiens)1624291UniProtKB:P05067 more ...RGDPMID:16049941 more ...
Pgam1Ratprotein kinase binding enablesISOPGAM1 (Homo sapiens)1624291UniProtKB:Q13153 and PMID:12189148RGDPMID:12189148
1 to 17 of 17 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgam1Ratglycolysis pathway   ISOPGAM1 (Homo sapiens)2302794 RGD 

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pgam1Ratgluconeogenesis pathway   IEA 6907045 KEGGrno:00010
Pgam1Ratglycolysis pathway   IEA 6907045 KEGGrno:00010
Pgam1Ratglycolysis/gluconeogenesis pathway  IEA 6907045 KEGGrno:00010

1 to 13 of 13 rows
#
Reference Title
Reference Citation
1. Nuclear location of phosphoglycerate mutase BB isozyme in rat tissues. Egea G, etal., Histochemistry. 1992;97(3):269-75.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. The histidine phosphatase superfamily: structure and function. Rigden DJ Biochem J. 2008 Jan 15;409(2):333-48.
11. Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus. Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
13. Isolation and sequencing of a cDNA encoding the B isozyme of rat phosphoglycerate mutase. Urena JM, etal., Gene 1992 Apr 15;113(2):281-2.
1 to 13 of 13 rows
PMID:1832843   PMID:2824255   PMID:4827367   PMID:11250083   PMID:12189148   PMID:15489334   PMID:16641100   PMID:17634366   PMID:18533197   PMID:19946888   PMID:20458337   PMID:22082260  
PMID:22420779   PMID:22590500   PMID:22871113   PMID:23376485   PMID:23533145   PMID:25002582  



Pgam1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81250,673,152 - 250,680,762 (+)NCBIGRCr8
mRatBN7.21240,723,832 - 240,731,443 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1240,723,920 - 240,738,452 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1248,868,982 - 248,876,729 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01255,566,135 - 255,573,881 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01248,219,147 - 248,226,892 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01261,158,204 - 261,165,814 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1261,158,261 - 261,165,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01268,610,733 - 268,618,280 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1236,559,231 - 236,566,463 (+)NCBICelera
Cytogenetic Map1q54NCBI
PGAM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381097,426,191 - 97,433,444 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1097,426,191 - 97,433,444 (+)EnsemblGRCh38hg38GRCh38
GRCh371099,185,948 - 99,193,201 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361099,176,017 - 99,183,188 (+)NCBINCBI36Build 36hg18NCBI36
Build 341099,176,016 - 99,183,187NCBI
Celera1092,924,180 - 92,931,355 (+)NCBICelera
Cytogenetic Map10q24.1NCBI
HuRef1092,811,681 - 92,818,852 (+)NCBIHuRef
CHM1_11099,467,767 - 99,474,938 (+)NCBICHM1_1
T2T-CHM13v2.01098,306,372 - 98,313,625 (+)NCBIT2T-CHM13v2.0
Pgam1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391941,900,310 - 41,907,104 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1941,900,362 - 41,907,099 (+)EnsemblGRCm39 Ensembl
GRCm381941,911,871 - 41,918,665 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1941,911,923 - 41,918,660 (+)EnsemblGRCm38mm10GRCm38
MGSCv371941,986,361 - 41,993,155 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361941,965,271 - 41,971,976 (+)NCBIMGSCv36mm8
Celera1942,711,451 - 42,718,243 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1935.44NCBI
Pgam1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555073,562,513 - 3,571,400 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555073,562,513 - 3,571,400 (+)NCBIChiLan1.0ChiLan1.0
PGAM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28109,340,381 - 109,347,709 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110109,345,921 - 109,353,028 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01094,048,829 - 94,056,082 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11097,542,558 - 97,549,867 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1097,542,558 - 97,549,867 (+)Ensemblpanpan1.1panPan2
PGAM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12810,720,235 - 10,727,709 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2810,720,094 - 10,930,286 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2810,902,930 - 10,910,408 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02811,042,559 - 11,050,038 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2811,042,496 - 11,050,038 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12810,703,632 - 10,711,101 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02810,764,397 - 10,771,643 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02810,904,327 - 10,911,807 (+)NCBIUU_Cfam_GSD_1.0
Pgam1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721336,201,336 - 36,209,529 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366362,236,508 - 2,248,768 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366362,240,452 - 2,248,689 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PGAM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14108,822,812 - 108,833,058 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114108,822,782 - 108,832,818 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214118,326,760 - 118,336,762 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PGAM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1990,581,593 - 90,585,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604851,492,428 - 51,500,247 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pgam1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247379,088,539 - 9,096,348 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247379,088,545 - 9,096,350 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Pgam1
19 total Variants

Predicted Target Of
Summary Value
Count of predictions:455
Count of miRNA genes:235
Interacting mature miRNAs:288
Transcripts:ENSRNOT00000071965
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 73 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat

1 to 10 of 73 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000071965   ⟹   ENSRNOP00000065690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1240,723,920 - 240,738,452 (+)Ensembl
Rnor_6.0 Ensembl1261,158,261 - 261,165,808 (+)Ensembl
RefSeq Acc Id: NM_053290   ⟹   NP_445742
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81250,673,152 - 250,680,762 (+)NCBI
mRatBN7.21240,723,832 - 240,731,443 (+)NCBI
Rnor_6.01261,158,204 - 261,165,814 (+)NCBI
Rnor_5.01268,610,733 - 268,618,280 (+)NCBI
Celera1236,559,231 - 236,566,463 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_445742 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41834 (Get FASTA)   NCBI Sequence Viewer  
  AAH65582 (Get FASTA)   NCBI Sequence Viewer  
  CBX85748 (Get FASTA)   NCBI Sequence Viewer  
  CBX85912 (Get FASTA)   NCBI Sequence Viewer  
  EDL94214 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065690
  ENSRNOP00000065690.1
GenBank Protein P25113 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_445742   ⟸   NM_053290
- UniProtKB: Q6P0K6 (UniProtKB/Swiss-Prot),   P25113 (UniProtKB/Swiss-Prot),   A6JH90 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065690   ⟸   ENSRNOT00000071965

Name Modeler Protein Id AA Range Protein Structure
AF-P25113-F1-model_v2 AlphaFold P25113 1-254 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690909
Promoter ID:EPDNEW_R1433
Type:initiation region
Name:Pgam1_1
Description:phosphoglycerate mutase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01261,158,326 - 261,158,386EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-55672 BioCyc
BioCyc Pathway ANAGLYCOLYSIS-PWY [glycolysis III (from glucose)] BioCyc
  PWY-6405 [Rapoport-Luebering glycolytic shunt] BioCyc
  PWY66-399 [gluconeogenesis III] BioCyc
BioCyc Pathway Image ANAGLYCOLYSIS-PWY BioCyc
  PWY-6405 BioCyc
  PWY66-399 BioCyc
Ensembl Genes ENSRNOG00000050585 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000071965 ENTREZGENE
  ENSRNOT00000071965.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1240 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5623677 IMAGE-MGC_LOAD
InterPro His_Pase_superF_clade-1 UniProtKB/Swiss-Prot
  His_PPase_superfam UniProtKB/Swiss-Prot
  PG/BPGM_mutase_AS UniProtKB/Swiss-Prot
  Phosphogly_mut1 UniProtKB/Swiss-Prot
KEGG Report rno:24642 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72368 IMAGE-MGC_LOAD
NCBI Gene 24642 ENTREZGENE
PANTHER PTHR11931 UniProtKB/Swiss-Prot
Pfam His_Phos_1 UniProtKB/Swiss-Prot
PhenoGen Pgam1 PhenoGen
PIRSF 6PFK_2-Ptase UniProtKB/Swiss-Prot
PROSITE PG_MUTASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000050585 RatGTEx
SMART PGAM UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53254 UniProtKB/Swiss-Prot
UniProt A6JH90 ENTREZGENE, UniProtKB/TrEMBL
  P25113 ENTREZGENE, UniProtKB/Swiss-Prot
  Q6P0K6 ENTREZGENE
UniProt Secondary Q6P0K6 UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Pgam1  phosphoglycerate mutase 1  Pgam1  phosphoglycerate mutase 1 (brain)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-17 Pgam1  phosphoglycerate mutase 1 (brain)  Pgam1  phosphoglycerate mutase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Pgam1  Phosphoglycerate mutase 1      Symbol and Name status set to approved 70586 APPROVED