Padi2 (peptidyl arginine deiminase 2) - Rat Genome Database

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Gene: Padi2 (peptidyl arginine deiminase 2) Rattus norvegicus
Analyze
Symbol: Padi2
Name: peptidyl arginine deiminase 2
RGD ID: 3288
Description: Enables protein-arginine deiminase activity. Predicted to be involved in several processes, including estrogen receptor signaling pathway; substantia nigra development; and transcription initiation-coupled chromatin remodeling. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in euchromatin. Predicted to be active in cytoplasm and nucleus. Orthologous to human PADI2 (peptidyl arginine deiminase 2); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Pdi2; peptidyl arginine deiminase type II; peptidyl arginine deiminase, type 2; peptidyl arginine deiminase, type II; peptidylarginine deiminase II; protein-arginine deiminase type II; protein-arginine deiminase type-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,492,087 - 158,534,662 (+)NCBIGRCr8
mRatBN7.25153,209,053 - 153,251,632 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,209,053 - 153,251,632 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,898,744 - 155,940,735 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,672,018 - 157,714,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,661,096 - 157,703,184 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,428,479 - 159,471,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,428,515 - 159,471,144 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,141,202 - 163,183,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,762,824 - 159,805,399 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,773,011 - 159,815,587 (+)NCBI
Celera5151,567,606 - 151,616,600 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Padi2RatCOVID-19  ISOPADI2 (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Padi2Ratchromosome 1p36 deletion syndrome  ISOPADI2 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 1p36 deletion syndromeClinVar 
Padi2Ratgastrointestinal stromal tumor  ISOPADI2 (Homo sapiens)8554872ClinVar Annotator: match by term: Gastrointestinal stromal tumorClinVarPMID:16258955 more ...
Padi2RatParagangliomas 4  ISOPADI2 (Homo sapiens)8554872ClinVar Annotator: match by term: Paragangliomas 4ClinVarPMID:18057081
Padi2Ratrheumatoid arthritis  ISOPADI2 (Homo sapiens)8554872ClinVar Annotator: match by term: Rheumatoid arthritisClinVar 

1 to 20 of 111 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Padi2Rat1,2-dimethylhydrazine decreases expressionISOPadi2 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of PADI2 mRNACTDPMID:22206623
Padi2Rat17alpha-ethynylestradiol increases expressionISOPadi2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of PADI2 mRNACTDPMID:17942748
Padi2Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of PADI2 mRNACTDPMID:12655037 and PMID:15834898
Padi2Rat17alpha-ethynylestradiol multiple interactionsISOPadi2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PADI2 mRNACTDPMID:17942748
Padi2Rat17alpha-ethynylestradiol affects expressionISOPadi2 (Mus musculus)6480464Ethinyl Estradiol affects the expression of PADI2 mRNACTDPMID:17555576
Padi2Rat17beta-estradiol increases expressionISOPADI2 (Homo sapiens)6480464Estradiol results in increased expression of PADI2 mRNACTDPMID:21185374 and PMID:31614463
Padi2Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PADI2 mRNACTDPMID:32741896
Padi2Rat17beta-estradiol multiple interactionsISOPADI2 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of PADI2 mRNACTDPMID:30165855
Padi2Rat17beta-estradiol increases expressionISOPadi2 (Mus musculus)6480464Estradiol results in increased expression of PADI2 mRNACTDPMID:15289156 more ...
Padi2Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of PADI2 mRNACTDPMID:32741896
Padi2Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOPadi2 (Mus musculus)64804642 more ...CTDPMID:31388691
Padi2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPadi2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PADI2 mRNACTDPMID:17942748
Padi2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PADI2 mRNACTDPMID:33387578
Padi2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PADI2 mRNACTDPMID:22298810 and PMID:34747641
Padi2Rat2-acetamidofluorene multiple interactionsISOPadi2 (Mus musculus)6480464TRP53 protein modified form affects the reaction [2-Acetylaminofluorene results in increased expression of PADI2 mRNA]CTDPMID:17317680
Padi2Rat4,4'-sulfonyldiphenol increases methylationISOPadi2 (Mus musculus)6480464bisphenol S results in increased methylation of PADI2 promoterCTDPMID:33297965
Padi2Rat4,4'-sulfonyldiphenol increases expressionISOPadi2 (Mus musculus)6480464bisphenol S results in increased expression of PADI2 mRNACTDPMID:34850234
Padi2Rat4-phenylbutyric acid decreases expressionISOPadi2 (Mus musculus)64804644-phenylbutyric acid results in decreased expression of PADI2 mRNACTDPMID:28698385
Padi2Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of PADI2 mRNACTDPMID:24780913 and PMID:25825206
Padi2Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PADI2 mRNACTDPMID:30047161

1 to 20 of 111 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Padi2Ratcytoplasm located_inISOPADI2 (Homo sapiens)1624291 PMID:12392711RGDPMID:12392711
Padi2Ratcytoplasm located_inIEAInterPro:IPR013530 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Padi2Ratcytoplasm is_active_inIBAMGI:2655198 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Padi2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Padi2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Padi2Ratcytoplasm located_inIEAUniRule:UR0014287571600115GO_REF:0000104UniProtGO_REF:0000104
Padi2Rateuchromatin located_inISOPADI2 (Homo sapiens)1624291 PMID:22853951RGDPMID:22853951
Padi2Ratnucleus is_active_inIBAPANTHER:PTN002586031 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Padi2Ratcalcium ion binding enablesIEAInterPro:IPR013530 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Padi2Ratcalcium ion binding enablesIEAUniRule:UR0014287571600115GO_REF:0000104UniProtGO_REF:0000104
Padi2Rathistone arginine deiminase activity enablesIBAPANTHER:PTN000089788 and UniProtKB:Q9Y2J81600115GO_REF:0000033GO_CentralGO_REF:0000033
Padi2Rathistone H3R26 arginine deiminase activity enablesISOPADI2 (Homo sapiens)1624291 PMID:22853951RGDPMID:22853951
Padi2Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Padi2Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Padi2Ratnuclear estrogen receptor binding enablesISOPADI2 (Homo sapiens)1624291UniProtKB:P03372 and PMID:22853951RGDPMID:22853951
Padi2Ratprotein homodimerization activity enablesISSUniProtKB:Q9Y2J81600115GO_REF:0000024UniProtGO_REF:0000024
Padi2Ratprotein homodimerization activity enablesISOPADI2 (Homo sapiens)1624291 PMID:25621824RGDPMID:25621824
Padi2Ratprotein-arginine deiminase activity enablesIDA 8554540PMID:12392711UniProt 
Padi2Ratprotein-arginine deiminase activity enablesIEAInterPro:IPR004303 and InterPro:IPR0135301600115GO_REF:0000002InterProGO_REF:0000002
Padi2Ratprotein-arginine deiminase activity enablesIEARHEA:180891600115GO_REF:0000116RHEAGO_REF:0000116
Padi2Ratprotein-arginine deiminase activity enablesIEAEC:3.5.3.151600115GO_REF:0000003UniProtGO_REF:0000003
Padi2Ratprotein-arginine deiminase activity enablesIEAUniRule:UR0014287571600115GO_REF:0000104UniProtGO_REF:0000104
Padi2Ratprotein-arginine deiminase activity enablesISOPADI2 (Homo sapiens)1624291 PMID:12392711 more ...RGDPMID:12392711 more ...
1 to 15 of 15 rows

BioCyc Pathways


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin. Ishigami A, etal., Arch Biochem Biophys. 2002 Nov 1;407(1):25-31.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
7. Isolation and characterization of cDNA clones encoding rat skeletal muscle peptidylarginine deiminase. Watanabe K and Senshu T, J Biol Chem 1989 Sep 15;264(26):15255-60.
PMID:1601308   PMID:15629448   PMID:17579814   PMID:18248664   PMID:18645041   PMID:19056867   PMID:19085382   PMID:19641855   PMID:20439489   PMID:22853951   PMID:22926577   PMID:25621824  



Padi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,492,087 - 158,534,662 (+)NCBIGRCr8
mRatBN7.25153,209,053 - 153,251,632 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,209,053 - 153,251,632 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,898,744 - 155,940,735 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,672,018 - 157,714,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,661,096 - 157,703,184 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,428,479 - 159,471,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,428,515 - 159,471,144 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,141,202 - 163,183,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,762,824 - 159,805,399 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,773,011 - 159,815,587 (+)NCBI
Celera5151,567,606 - 151,616,600 (+)NCBICelera
Cytogenetic Map5q36NCBI
PADI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,066,761 - 17,119,451 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,066,761 - 17,119,451 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,393,256 - 17,445,946 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,265,843 - 17,318,535 (-)NCBINCBI36Build 36hg18NCBI36
Build 34117,140,558 - 17,191,236NCBI
Celera115,715,602 - 15,768,303 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,637,268 - 15,689,337 (-)NCBIHuRef
CHM1_1117,501,602 - 17,554,329 (-)NCBICHM1_1
T2T-CHM13v2.0116,877,198 - 16,929,905 (-)NCBIT2T-CHM13v2.0
Padi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,633,685 - 140,679,897 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,633,655 - 140,679,897 (+)EnsemblGRCm39 Ensembl
GRCm384140,906,336 - 140,952,586 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,906,344 - 140,952,586 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,462,275 - 140,508,501 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,644,091 - 138,693,178 (+)NCBIMGSCv36mm8
MGSCv364140,178,503 - 140,224,662 (+)NCBIMGSCv36mm8
Celera4142,714,994 - 142,753,117 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.01NCBI
Padi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,709,444 - 1,752,783 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,709,307 - 1,751,332 (+)NCBIChiLan1.0ChiLan1.0
PADI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,009,732 - 210,062,423 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,128,609 - 209,181,304 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,011,708 - 16,064,344 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,067,729 - 17,120,513 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,067,729 - 17,120,513 (-)Ensemblpanpan1.1panPan2
PADI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,116,031 - 81,147,889 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,116,140 - 81,145,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,641,018 - 77,685,332 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,749,888 - 81,794,334 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,749,859 - 81,794,317 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,502,939 - 78,547,380 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,519,889 - 79,564,357 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,588,375 - 80,632,825 (+)NCBIUU_Cfam_GSD_1.0
Padi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,210,290 - 38,236,848 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,033,230 - 4,088,256 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364744,033,703 - 4,066,468 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PADI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,696,481 - 75,755,890 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,696,476 - 75,755,977 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2670,039,608 - 70,099,180 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PADI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,465,098 - 115,520,772 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,465,338 - 115,520,828 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033596,810 - 650,559 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Padi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,693,060 - 2,734,107 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,693,276 - 2,734,070 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Padi2
520 total Variants

Predicted Target Of
Summary Value
Count of predictions:132
Count of miRNA genes:90
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000010183
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 32 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5151113452164465185Rat

1 to 10 of 32 rows
RH128094  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85158,534,420 - 158,534,616 (+)Marker Load Pipeline
mRatBN7.25153,251,389 - 153,251,585 (+)MAPPERmRatBN7.2
Rnor_6.05159,470,862 - 159,471,057NCBIRnor6.0
Rnor_5.05163,183,533 - 163,183,728UniSTSRnor5.0
RGSC_v3.45159,805,157 - 159,805,352UniSTSRGSC3.4
Celera5151,616,358 - 151,616,553UniSTS
Cytogenetic Map5q36UniSTS
RH132527  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr85158,505,861 - 158,506,588 (+)Marker Load Pipeline
mRatBN7.25153,222,829 - 153,223,556 (+)MAPPERmRatBN7.2
Rnor_6.05159,442,304 - 159,443,030NCBIRnor6.0
Rnor_5.05163,154,977 - 163,155,703UniSTSRnor5.0
RGSC_v3.45159,776,599 - 159,777,325UniSTSRGSC3.4
Celera5151,581,380 - 151,582,106UniSTS
RH 3.4 Map51051.3UniSTS
Cytogenetic Map5q36UniSTS
BF386039  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,207,243 - 153,207,417 (+)MAPPERmRatBN7.2
Rnor_6.05159,426,720 - 159,426,893NCBIRnor6.0
Rnor_5.05163,139,393 - 163,139,566UniSTSRnor5.0
RGSC_v3.45159,761,015 - 159,761,188UniSTSRGSC3.4
Celera5151,565,797 - 151,565,970UniSTS
RH 3.4 Map51052.9UniSTS
Cytogenetic Map5q36UniSTS
BI297266  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25153,224,951 - 153,225,115 (+)MAPPERmRatBN7.2
Rnor_6.05159,444,426 - 159,444,589NCBIRnor6.0
Rnor_5.05163,157,099 - 163,157,262UniSTSRnor5.0
RGSC_v3.45159,778,721 - 159,778,884UniSTSRGSC3.4
Celera5151,583,502 - 151,583,665UniSTS
RH 3.4 Map51053.1UniSTS
Cytogenetic Map5q36UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000010183   ⟹   ENSRNOP00000010183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5153,209,053 - 153,251,632 (+)Ensembl
Rnor_6.0 Ensembl5159,428,515 - 159,471,144 (+)Ensembl
RefSeq Acc Id: NM_017226   ⟹   NP_058922
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85158,492,087 - 158,534,662 (+)NCBI
mRatBN7.25153,209,053 - 153,251,632 (+)NCBI
Rnor_6.05159,428,529 - 159,471,104 (+)NCBI
Rnor_5.05163,141,202 - 163,183,775 (+)NCBI
RGSC_v3.45159,762,824 - 159,805,399 (+)RGD
Celera5151,567,606 - 151,616,600 (+)RGD
Sequence:
Protein RefSeqs NP_058922 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41793 (Get FASTA)   NCBI Sequence Viewer  
  BAA01253 (Get FASTA)   NCBI Sequence Viewer  
  EDL80949 (Get FASTA)   NCBI Sequence Viewer  
  EDL80950 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010183
GenBank Protein P20717 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_058922   ⟸   NM_017226
- UniProtKB: P20717 (UniProtKB/Swiss-Prot),   A6ITP8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010183   ⟸   ENSRNOT00000010183
Name Modeler Protein Id AA Range Protein Structure
AF-P20717-F1-model_v2 AlphaFold P20717 1-665 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694214
Promoter ID:EPDNEW_R4738
Type:single initiation site
Name:Padi2_1
Description:peptidyl arginine deiminase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05159,428,508 - 159,428,568EPDNEW


1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-39376 BioCyc
BioCyc Pathway PWY-4921 [protein citrullination] BioCyc
BioCyc Pathway Image PWY-4921 BioCyc
Ensembl Genes ENSRNOG00000007574 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000010183 ENTREZGENE
Gene3D-CATH 2.60.40.1700 UniProtKB/Swiss-Prot
  2.60.40.1860 UniProtKB/Swiss-Prot
  L-arginine/glycine Amidinotransferase, Chain A UniProtKB/Swiss-Prot
InterPro Cupredoxin UniProtKB/Swiss-Prot
  PAD UniProtKB/Swiss-Prot
  PAD_C UniProtKB/Swiss-Prot
  PAD_central_sf UniProtKB/Swiss-Prot
  PAD_N UniProtKB/Swiss-Prot
  PAD_N_sf UniProtKB/Swiss-Prot
  Prot_Arg_deaminase_cen_dom UniProtKB/Swiss-Prot
KEGG Report rno:29511 UniProtKB/Swiss-Prot
NCBI Gene 29511 ENTREZGENE
PANTHER PROTEIN-ARGININE DEIMINASE TYPE-2 UniProtKB/Swiss-Prot
  PTHR10837 UniProtKB/Swiss-Prot
Pfam PAD UniProtKB/Swiss-Prot
  PAD_M UniProtKB/Swiss-Prot
  PAD_N UniProtKB/Swiss-Prot
PhenoGen Padi2 PhenoGen
PIRSF Protein-arginine_deiminase UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007574 RatGTEx
Superfamily-SCOP Pentein UniProtKB/Swiss-Prot
  SSF110083 UniProtKB/Swiss-Prot
  SSF49503 UniProtKB/Swiss-Prot
TIGR TC230849
UniProt A6ITP8 ENTREZGENE, UniProtKB/TrEMBL
  A6ITP9_RAT UniProtKB/TrEMBL
  F1LPA6_RAT UniProtKB/TrEMBL
  P20717 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-14 Padi2  peptidyl arginine deiminase 2  Padi2  peptidyl arginine deiminase, type II  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Padi2  peptidyl arginine deiminase, type II  Pdi2  peptidyl arginine deiminase, type 2  Symbol and Name updated 1299863 APPROVED
2002-06-10 Pdi2  peptidyl arginine deiminase, type 2      Name updated 70585 PROVISIONAL

Note Type Note Reference
gene_product member of a family of peptidylarginine deiminases 69925