Pcp4 (Purkinje cell protein 4) - Rat Genome Database

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Gene: Pcp4 (Purkinje cell protein 4) Rattus norvegicus
Analyze
Symbol: Pcp4
Name: Purkinje cell protein 4
RGD ID: 3271
Description: Enables RNA binding activity and calmodulin binding activity. Involved in several processes, including cellular response to L-glutamate; osteoblast differentiation; and positive regulation of dopamine secretion. Located in axon and neurofilament. Biomarker of status epilepticus. Orthologous to human PCP4 (Purkinje cell protein 4); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: brain-specific antigen PCP-4; brain-specific polypeptide PEP-19; calmodulin regulator protein PCP4; LOC102551106; Neuron specific protein PEP-19 (Purkinje cell protein 4); neuron-specific protein PEP-19; pep-19; PEPZ19; uncharacterized LOC102551106
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81149,229,185 - 49,331,186 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1149,270,186 - 49,331,186 (+)EnsemblGRCr8
mRatBN7.21135,759,711 - 35,861,725 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,800,713 - 35,861,725 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1144,450,446 - 44,511,455 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,121,822 - 37,182,837 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,275,044 - 36,336,059 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,851,035 - 36,912,272 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,851,038 - 36,912,229 (+)Ensemblrn6Rnor6.0
Rnor_5.01142,825,722 - 42,855,529 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41136,828,273 - 36,889,381 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1135,698,717 - 35,758,778 (+)NCBICelera
RGSC_v3.11136,885,861 - 36,946,969 (+)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
aflatoxin B1  (EXP,ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
bromobenzene  (EXP)
Butylbenzyl phthalate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cocaine  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
coumestrol  (ISO)
dexamethasone  (EXP)
dibutyl phthalate  (EXP)
diethyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (EXP,ISO)
flurbiprofen  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glycine betaine  (EXP)
L-ascorbic acid  (EXP)
methamphetamine  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrofen  (EXP)
paraquat  (EXP)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenylephrine  (EXP)
PhIP  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
potassium dichromate  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sunitinib  (ISO)
testosterone  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
undecane  (EXP)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
calcium ion binding  (IBA,ISO,ISS)
calmodulin binding  (IBA,IDA,IEA,ISO)
protein binding  (ISO)
RNA binding  (IDA)

References

References - curated
# Reference Title Reference Citation
1. Expression of PEP-19 inhibits apoptosis in PC12 cells. Erhardt JA, etal., Neuroreport. 2000 Nov 27;11(17):3719-23.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Gene expression in the rat supraoptic nucleus induced by chronic hyperosmolality versus hyposmolality. Glasgow E, etal., Am J Physiol Regul Integr Comp Physiol. 2000 Oct;279(4):R1239-50.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Purkinje cell protein 4 positively regulates neurite outgrowth and neurotransmitter release. Harashima S, etal., J Neurosci Res. 2011 Oct;89(10):1519-30. doi: 10.1002/jnr.22688. Epub 2011 Jun 10.
6. Peptide 19-immunoreactive primary sensory neurons in the rat trigeminal ganglion. Ichikawa H and Sugimoto T, Brain Res. 1999 Nov 6;846(2):274-9.
7. Calmodulin-binding peptide PEP-19 modulates activation of calmodulin kinase II In situ. Johanson RA, etal., J Neurosci. 2000 Apr 15;20(8):2860-6.
8. PEP-19 overexpression in human uterine leiomyoma. Kanamori T, etal., Mol Hum Reprod. 2003 Nov;9(11):709-17.
9. Degradation of PEP-19, a calmodulin-binding protein, by calpain is implicated in neuronal cell death induced by intracellular Ca2+ overload. Kanazawa Y, etal., Neuroscience. 2008 Jun 23;154(2):473-81. doi: 10.1016/j.neuroscience.2008.03.044. Epub 2008 Mar 26.
10. Transcriptome analysis of the hippocampal CA1 pyramidal cell region after kainic acid-induced status epilepticus in juvenile rats. Lauren HB, etal., PLoS One. 2010 May 20;5(5):e10733. doi: 10.1371/journal.pone.0010733.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. RNA-binding activity of the rat calmodulin-binding PEP-19 protein and of the long PEP-19 isoform. Saladino P, etal., Int J Mol Med. 2012 Feb;29(2):141-5. doi: 10.3892/ijmm.2011.819. Epub 2011 Oct 20.
16. Molecular cloning of a neuron-specific transcript and its regulation during normal and aberrant cerebellar development. Sangameswaran L, etal., Proc Natl Acad Sci U S A 1989 Jul;86(14):5651-5.
17. Gene expression profiling during rat mammary carcinogenesis induced by 7,12-dimethylbenzanthracene. Souda M, etal., Int J Cancer. 2009 Sep 15;125(6):1285-97. doi: 10.1002/ijc.24396.
18. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
19. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
20. PEP-19 immunohistochemistry defines the basal ganglia and associated structures in the adult human brain, and is dramatically reduced in Huntington's disease. Utal AK, etal., Neuroscience. 1998 Oct;86(4):1055-63.
21. Expression of Pcp4 gene during osteogenic differentiation of bone marrow mesenchymal stem cells in vitro. Xiao J, etal., Mol Cell Biochem. 2008 Feb;309(1-2):143-50. Epub 2007 Nov 16.
Additional References at PubMed
PMID:3464961   PMID:12060780   PMID:15489334   PMID:16780588   PMID:17273800   PMID:19106096   PMID:21491429   PMID:22197496   PMID:22458599   PMID:23204517   PMID:25048017   PMID:31686426  


Genomics

Comparative Map Data
Pcp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81149,229,185 - 49,331,186 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1149,270,186 - 49,331,186 (+)EnsemblGRCr8
mRatBN7.21135,759,711 - 35,861,725 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1135,800,713 - 35,861,725 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1144,450,446 - 44,511,455 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,121,822 - 37,182,837 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,275,044 - 36,336,059 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01136,851,035 - 36,912,272 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1136,851,038 - 36,912,229 (+)Ensemblrn6Rnor6.0
Rnor_5.01142,825,722 - 42,855,529 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41136,828,273 - 36,889,381 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1135,698,717 - 35,758,778 (+)NCBICelera
RGSC_v3.11136,885,861 - 36,946,969 (+)NCBI
Cytogenetic Map11q11NCBI
PCP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382139,867,438 - 39,929,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2139,867,438 - 39,929,397 (+)Ensemblhg38GRCh38
GRCh372141,239,364 - 41,301,317 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362140,161,217 - 40,223,192 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342140,161,216 - 40,223,190NCBI
Celera2126,436,822 - 26,498,803 (+)NCBICelera
Cytogenetic Map21q22.2NCBI
HuRef2126,708,625 - 26,770,649 (+)NCBIHuRef
CHM1_12140,800,092 - 40,862,070 (+)NCBICHM1_1
T2T-CHM13v2.02138,251,577 - 38,313,599 (+)NCBIT2T-CHM13v2.0
Pcp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391696,268,806 - 96,326,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1696,268,806 - 96,326,993 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381696,467,606 - 96,525,793 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1696,467,606 - 96,525,793 (+)Ensemblmm10GRCm38
MGSCv371696,689,213 - 96,747,396 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361696,572,516 - 96,630,703 (+)NCBIMGSCv36mm8
Celera1697,545,310 - 97,603,962 (+)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1656.97NCBI
Pcp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540739,853,034 - 39,908,151 (+)Ensembl
ChiLan1.0NW_00495540739,853,029 - 39,908,151 (+)NCBIChiLan1.0ChiLan1.0
PCP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22235,967,343 - 36,029,032 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12130,823,340 - 30,885,002 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02126,069,039 - 26,284,247 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12139,556,995 - 39,618,734 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2139,587,400 - 39,618,734 (+)EnsemblpanPan2panpan1.1
PCP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13134,529,688 - 34,584,497 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3134,529,683 - 34,584,501 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3133,806,794 - 33,861,644 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03134,042,065 - 34,096,949 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3134,042,060 - 34,096,953 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13133,911,758 - 33,966,609 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03133,917,714 - 33,972,563 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03134,410,101 - 34,464,804 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pcp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497133,998,889 - 34,050,983 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365003,416,797 - 3,469,053 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365003,416,840 - 3,468,893 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PCP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13203,412,479 - 203,479,209 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113203,412,479 - 203,479,216 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PCP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1283,791,520 - 83,855,289 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl283,791,458 - 83,855,336 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605411,658,279 - 11,722,107 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pcp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474529,630,747 - 29,682,995 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474529,630,990 - 29,682,965 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pcp4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1448,141,731 - 48,201,218 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Pcp4
620 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:99
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000002221, ENSRNOT00000061047
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)111080612555806125Rat
634341Bw121Body weight QTL 1213.56abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)113532319955805892Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)112995899657754989Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)113191546976915469Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)112631803155806125Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111282315257823152Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
631510Spl2Serum phospholipid level QTL 24.1blood phospholipid amount (VT:0006084)serum phospholipid level (CMO:0001171)112755668572556685Rat

Markers in Region
RH130970  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21135,861,456 - 35,861,641 (+)MAPPERmRatBN7.2
Rnor_6.01136,912,004 - 36,912,188NCBIRnor6.0
Rnor_5.01140,437,848 - 40,438,032UniSTSRnor5.0
RGSC_v3.41136,889,159 - 36,889,343UniSTSRGSC3.4
Celera1135,758,510 - 35,758,694UniSTS
RH 3.4 Map11263.2UniSTS
Cytogenetic Map11q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 10 59 163 80 79 48 81 48 6 313 167 11 139 75 90 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002221   ⟹   ENSRNOP00000002221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,270,186 - 49,331,186 (+)Ensembl
mRatBN7.2 Ensembl1135,800,713 - 35,861,725 (+)Ensembl
Rnor_6.0 Ensembl1136,851,038 - 36,912,229 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000061047   ⟹   ENSRNOP00000057764
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,270,186 - 49,331,186 (+)Ensembl
mRatBN7.2 Ensembl1135,800,713 - 35,861,725 (+)Ensembl
Rnor_6.0 Ensembl1136,851,038 - 36,912,229 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105621   ⟹   ENSRNOP00000082469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1149,299,117 - 49,331,186 (+)Ensembl
mRatBN7.2 Ensembl1135,829,648 - 35,861,725 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119525   ⟹   ENSRNOP00000085635
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1135,859,602 - 35,861,725 (+)Ensembl
RefSeq Acc Id: NM_001270538   ⟹   NP_001257467
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,270,186 - 49,331,186 (+)NCBI
mRatBN7.21135,800,713 - 35,861,725 (+)NCBI
Rnor_6.01136,851,035 - 36,912,272 (+)NCBI
Celera1135,698,717 - 35,758,778 (+)NCBI
Sequence:
RefSeq Acc Id: NM_013002   ⟹   NP_037134
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,270,186 - 49,331,186 (+)NCBI
mRatBN7.21135,800,713 - 35,861,725 (+)NCBI
Rnor_6.01136,851,035 - 36,912,272 (+)NCBI
Rnor_5.01142,825,722 - 42,855,529 (+)NCBI
RGSC_v3.41136,828,273 - 36,889,381 (+)RGD
Celera1135,698,717 - 35,758,778 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088042   ⟹   XP_038943970
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81149,229,185 - 49,331,145 (+)NCBI
mRatBN7.21135,759,711 - 35,861,684 (+)NCBI
RefSeq Acc Id: NP_037134   ⟸   NM_013002
- Peptide Label: isoform PEP19
- UniProtKB: P63055 (UniProtKB/Swiss-Prot),   A0A8I5ZX37 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257467   ⟸   NM_001270538
- Peptide Label: isoform LPI
- UniProtKB: Q8CHN7 (UniProtKB/TrEMBL),   F7F9D7 (UniProtKB/TrEMBL),   A0A8I6A0K8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000057764   ⟸   ENSRNOT00000061047
Ensembl Acc Id: ENSRNOP00000002221   ⟸   ENSRNOT00000002221
RefSeq Acc Id: XP_038943970   ⟸   XM_039088042
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZX37 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082469   ⟸   ENSRNOT00000105621
Ensembl Acc Id: ENSRNOP00000085635   ⟸   ENSRNOT00000119525
Protein Domains
IQ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63055-F1-model_v2 AlphaFold P63055 1-62 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3271 AgrOrtholog
BioCyc Gene G2FUF-21702 BioCyc
Ensembl Genes ENSRNOG00000001628 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002221 ENTREZGENE
  ENSRNOT00000061047 ENTREZGENE
  ENSRNOT00000061047.4 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6888437 IMAGE-MGC_LOAD
InterPro Calmodulin_Regulator_PCP4-like UniProtKB/Swiss-Prot
KEGG Report rno:25510 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72910 IMAGE-MGC_LOAD
NCBI Gene 25510 ENTREZGENE
PANTHER IG-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  PTHR15359:SF7 UniProtKB/Swiss-Prot
PhenoGen Pcp4 PhenoGen
RatGTEx ENSRNOG00000001628 RatGTEx
TIGR TC216655
UniProt A0A8I5ZX37 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A0K8 ENTREZGENE
  A6IQF3_RAT UniProtKB/TrEMBL
  A6IQF4_RAT UniProtKB/TrEMBL
  F7F9D7 ENTREZGENE, UniProtKB/TrEMBL
  P63055 ENTREZGENE, UniProtKB/Swiss-Prot
  Q8CHN7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P07734 UniProtKB/Swiss-Prot
  Q63890 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Pcp4  Purkinje cell protein 4  LOC102551106  uncharacterized LOC102551106  Data merged from RGD:7703115 737654 PROVISIONAL
2013-12-18 LOC102551106  uncharacterized LOC102551106      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in cerebellum, thalamus caudate putamen, and olfactory bulb 633595