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Gene: Mxi1 (MAX interactor 1, dimerization protein) Rattus norvegicus

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Symbol:

Mxi1

Name:

MAX interactor 1, dimerization protein

RGD ID:

3128

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Used to study breast adenocarcinoma and esophageal cancer. Human ortholog(s) of this gene implicated in neurofibrosarcoma and prostate cancer. Orthologous to human MXI1 (MAX interactor 1, dimerization protein); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-ethoxyethanol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC100360467; LOC100360898; Max interacting protein 1; MAX interactor 1; Max interactor 1-like; MAX-interacting protein 1; MXI-WR

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	262,329,274 - 262,389,037 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	262,328,875 - 262,389,036 (+)	Ensembl				GRCr8
mRatBN7.2	1	252,323,915 - 252,383,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	252,323,303 - 252,383,681 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	260,532,436 - 260,572,821 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	267,238,502 - 267,278,887 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	259,894,073 - 259,934,513 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	274,030,748 - 274,090,071 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	274,030,978 - 274,090,071 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	281,443,967 - 281,503,729 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	259,219,584 - 259,259,979 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	248,065,618 - 248,106,019 (+)	NCBI		Celera
RGSC_v3.1	1	259,720,129 - 259,760,524 (+)	NCBI
RH 3.4 Map	1	1664.7	RGD
Cytogenetic Map	1	q55	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast adenocarcinoma (IAGP)

esophageal cancer (IAGP)

kidney disease (ISO)

neurofibrosarcoma (ISO)

ovarian cancer (ISO)

prostate cancer (ISO)

Prostatic Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

14-Deoxy-11,12-didehydroandrographolide (ISO)

17alpha-ethynylestradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-deoxy-D-glucose (ISO)

2-ethoxyethanol (EXP)

2-methoxyethanol (EXP)

3H-1,2-dithiole-3-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

acrylamide (EXP)

adefovir pivoxil (ISO)

aflatoxin B1 (EXP)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bleomycin A2 (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

chlorpyrifos (ISO)

choline (ISO)

chromium(6+) (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

clofibrate (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

CU-O LINKAGE (ISO)

cyclophosphamide (ISO)

cyclosporin A (ISO)

DDT (EXP)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

etoposide (ISO)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gemcitabine (ISO)

gentamycin (EXP)

geraniol (ISO)

glafenine (EXP)

GSK-J4 (ISO)

hexadecanoic acid (ISO)

hydroxyurea (ISO)

ifosfamide (ISO)

L-methionine (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

methylseleninic acid (ISO)

mitoxantrone (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

nickel dichloride (ISO)

niclosamide (ISO)

nitroglycerin (EXP)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP)

permethrin (EXP)

Pf-06840003 (ISO)

phenethyl caffeate (EXP)

quercetin (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

tamoxifen (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst formation (ISO)

DNA-templated transcription (IEA)

negative regulation of transcription by RNA polymerase II (ISO)

regulation of DNA-templated transcription (IDA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleoplasm (ISO)

nucleus (IEA,ISO)

RNA polymerase II transcription regulator complex (ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

protein binding (ISO)

protein dimerization activity (IEA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Mutation of the MXI1 gene in prostate cancer.	Eagle LR, etal., Nat Genet. 1995 Mar;9(3):249-55.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
5.	Mxi1 mutations in human neurofibrosarcomas.	Li XJ, etal., Jpn J Cancer Res. 1999 Jul;90(7):740-6.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
8.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
9.	GOA pipeline	RGD automated data pipeline
10.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
12.	The influence of H-2 gene products on cell-mediated and humoral immune responses.	von Boehmer H, etal., Cold Spring Harb Symp Quant Biol 1977;41 Pt 2:539-45.
13.	Mxi1 is a potential cellular target of carcinogens and frequently mutated in experimental rat tumors and tumor cell lines.	Wang DY, etal., Pathol Int 2000 May;50(5):373-83.
14.	Expression and subcellular localization of the Myc superfamily proteins: c-Myc, Max, Mad1 and Mxi1 in the epiphyseal plate cartilage chondrocytes of growing rats.	Wang Y, etal., Cell Mol Biol (Noisy-le-grand). 1997 Mar;43(2):175-88.
15.	Dynamic in vivo interactions among Myc network members.	Yin X, etal., Oncogene 2001 Aug 2;20(34):4650-64.

Additional References at PubMed

PMID:8425219	PMID:11875718	PMID:12477932	PMID:15467743	PMID:27869233

Genomics

Comparative Map Data

Mxi1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	262,329,274 - 262,389,037 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	262,328,875 - 262,389,036 (+)	Ensembl				GRCr8
mRatBN7.2	1	252,323,915 - 252,383,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	252,323,303 - 252,383,681 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	260,532,436 - 260,572,821 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	267,238,502 - 267,278,887 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	259,894,073 - 259,934,513 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	274,030,748 - 274,090,071 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	274,030,978 - 274,090,071 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	281,443,967 - 281,503,729 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	259,219,584 - 259,259,979 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	248,065,618 - 248,106,019 (+)	NCBI		Celera
RGSC_v3.1	1	259,720,129 - 259,760,524 (+)	NCBI
RH 3.4 Map	1	1664.7	RGD
Cytogenetic Map	1	q55	NCBI

MXI1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	110,207,605 - 110,287,365 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	110,207,605 - 110,287,365 (+)	Ensembl			hg38	GRCh38
GRCh37	10	111,967,363 - 112,047,123 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	111,957,353 - 112,037,113 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	111,975,751 - 112,037,113	NCBI
Celera	10	105,699,035 - 105,778,792 (+)	NCBI		Celera
Cytogenetic Map	10	q25.2	NCBI
HuRef	10	105,597,875 - 105,677,336 (+)	NCBI		HuRef
CHM1_1	10	112,249,113 - 112,328,883 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	111,091,474 - 111,171,229 (+)	NCBI		T2T-CHM13v2.0

Mxi1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	53,298,509 - 53,361,724 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	53,298,949 - 53,364,241 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	19	53,310,128 - 53,373,293 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	53,310,518 - 53,375,810 (+)	Ensembl			mm10	GRCm38
MGSCv37	19	53,384,996 - 53,450,300 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	19	53,363,833 - 53,426,600 (+)	NCBI		MGSCv36	mm8
Celera	19	55,492,539 - 55,557,842 (+)	NCBI		Celera
Cytogenetic Map	19	D2	NCBI
cM Map	19	47.53	NCBI

Mxi1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955485	1,088,175 - 1,156,925 (-)	Ensembl
ChiLan1.0	NW_004955485	1,088,175 - 1,156,521 (-)	NCBI	ChiLan1.0	ChiLan1.0

MXI1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	122,085,056 - 122,165,519 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	122,090,519 - 122,170,854 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	106,799,511 - 106,878,697 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	110,252,184 - 110,328,782 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2

MXI1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	21,584,856 - 21,655,233 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	21,584,638 - 21,652,920 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	21,727,467 - 21,808,682 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	22,099,102 - 22,180,921 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	22,099,304 - 22,182,100 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	21,659,914 - 21,741,144 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	21,663,825 - 21,745,111 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	21,799,743 - 21,880,999 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Mxi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	24,384,066 - 24,459,537 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	1,101,552 - 1,177,220 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936486	1,103,908 - 1,173,982 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MXI1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	120,643,830 - 120,724,099 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	120,643,691 - 120,722,632 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	131,570,946 - 131,610,162 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MXI1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	103,131,534 - 103,211,609 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	103,131,420 - 103,209,231 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	64,334,329 - 64,414,023 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mxi1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	35,955,726 - 36,034,695 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624737	35,956,443 - 36,034,678 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Mxi1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	52,760,845 - 52,801,616 (+)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	184
Count of miRNA genes:	114
Interacting mature miRNAs:	148
Transcripts:	ENSRNOT00000042822
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	208479811	269633915	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
70211	Niddm24	Non-insulin dependent diabetes mellitus QTL 24	3.79		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	224633915	269633915	Rat
724552	Glom2	Glomerulus QTL 2	3.3	0.0001	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	1	232312773	270518180	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	186658830	266453731	Rat
61327	Eae7	Experimental allergic encephalomyelitis QTL 7	5.6		body mass (VT:0001259)	change in body weight (CMO:0002045)	1	226175591	270518180	Rat
1578775	Iddm21	Insulin dependent diabetes mellitus QTL 21	4.13		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	245782829	270518180	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	205233991	267096252	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	218829748	263829748	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	186658830	266453731	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
631837	Niddm35	Non-insulin dependent diabetes mellitus QTL 35		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	248619887	269633915	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631836	Stl31	Serum triglyceride level QTL 31	4.64	5e-06	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	247133834	270518180	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	205233991	267096252	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1600390	Niddm64	Non-insulin dependent diabetes mellitus QTL 64		0.003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	257624997	270518180	Rat
1300108	Rf8	Renal function QTL 8	3.75		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	1	237995023	269633915	Rat
734767	Niddm57	Non-insulin dependent diabetes mellitus QTL 57			body mass (VT:0001259)	body weight (CMO:0000012)	1	233480549	270108840	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
631215	Stl8	Serum triglyceride level QTL 8	9.27	0.0001	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	1	234540191	270518180	Rat
7387289	Uae45	Urinary albumin excretion QTL 45	2.86	0.0021	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	233204160	270518180	Rat
631843	Bw116	Body weight QTL 116	4.1	0.016	abdominal adipose amount (VT:1000220)	abdominal fat pad weight (CMO:0000088)	1	233480549	270108840	Rat
731175	Uae20	Urinary albumin excretion QTL 20	3.5	0.0018	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	207163993	269633915	Rat
1598839	Rf56	Renal function QTL 56			renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	255849111	270518180	Rat
1581544	Rf52	Renal function QTL 52		0.05	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	1	241569529	269633915	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
631536	Lnnr2	Liver neoplastic nodule remodeling QTL 2	2.9	0.0005	liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)	1	243953669	270518180	Rat
734769	Niddm58	Non-insulin dependent diabetes mellitus QTL 58			body mass (VT:0001259)	body weight (CMO:0000012)	1	225108840	270108840	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	185857683	270518180	Rat
2302040	Pia35	Pristane induced arthritis QTL 35	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	226175591	270518180	Rat
631669	Iddm9	Insulin dependent diabetes mellitus QTL 9	2.8	0.039	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	233349180	270518180	Rat
1598821	Rf55	Renal function QTL 55	6.3		renal blood flow trait (VT:2000006)	ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)	1	228174566	270518180	Rat
724533	Rf51	Renal function QTL 51	5.3	0.0002	kidney plasma flow trait (VT:0005524)	renal plasma flow (CMO:0001914)	1	228180370	266453608	Rat

Markers in Region

RH127398

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	252,383,464 - 252,383,644 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	274,089,854 - 274,090,033	NCBI	Rnor6.0
Rnor_5.0	1	281,503,512 - 281,503,691	UniSTS	Rnor5.0
Celera	1	248,105,802 - 248,105,981	UniSTS
RH 3.4 Map	1	1665.3	UniSTS
Cytogenetic Map	1	q55	UniSTS

BG376247

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	252,382,445 - 252,382,555 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	274,088,835 - 274,088,944	NCBI	Rnor6.0
Rnor_5.0	1	281,502,493 - 281,502,602	UniSTS	Rnor5.0
Celera	1	248,104,783 - 248,104,892	UniSTS
RH 3.4 Map	1	1670.6	UniSTS
Cytogenetic Map	1	q55	UniSTS

RH94430

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	262,387,524 - 262,387,688 (+)	Marker Load Pipeline
Rnor_5.0	1	281,502,217 - 281,502,380	NCBI	Rnor5.0
RGSC_v3.4	1	259,220,933 - 259,221,095	UniSTS	RGSC3.4
RH 3.4 Map	1	1664.7	UniSTS
Cytogenetic Map	1	q55	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001439931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001439932	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_013160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231605	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588832	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC106606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF003008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY495712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081824	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223663	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U44728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000042822 ⟹ ENSRNOP00000040770

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	262,348,728 - 262,389,031 (+)	Ensembl
mRatBN7.2 Ensembl	1	252,343,285 - 252,383,681 (+)	Ensembl
Rnor_6.0 Ensembl	1	274,049,676 - 274,090,071 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076387 ⟹ ENSRNOP00000068001

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	262,336,654 - 262,389,036 (+)	Ensembl
mRatBN7.2 Ensembl	1	252,323,303 - 252,383,681 (+)	Ensembl
Rnor_6.0 Ensembl	1	274,030,978 - 274,090,066 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076779 ⟹ ENSRNOP00000067990

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	262,348,492 - 262,389,031 (+)	Ensembl
mRatBN7.2 Ensembl	1	252,343,252 - 252,383,681 (+)	Ensembl
Rnor_6.0 Ensembl	1	274,049,533 - 274,090,070 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000150550 ⟹ ENSRNOP00000107728

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	262,328,875 - 262,389,031 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000165038 ⟹ ENSRNOP00000105405

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	262,329,755 - 262,389,036 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169888 ⟹ ENSRNOP00000104233

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	262,329,489 - 262,389,036 (+)	Ensembl

RefSeq Acc Id:

NM_013160 ⟹ NP_037292

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	262,348,642 - 262,389,037 (+)	NCBI
mRatBN7.2	1	252,343,285 - 252,383,682 (+)	NCBI
Rnor_6.0	1	274,049,676 - 274,090,071 (+)	NCBI
Rnor_5.0	1	281,443,967 - 281,503,729 (+)	NCBI
RGSC_v3.4	1	259,219,584 - 259,259,979 (-)	RGD
Celera	1	248,065,618 - 248,106,019 (+)	RGD

Sequence:

show sequence

GCCGTCTGTGGCGCCTCCTGTCGGCCGGGGGCGGGAGCGCGGAGCCCATGGAGCGGGTGCGGAT
GATCAACGTGCAGCGCCTGCTGGAGGCCGCGGAGTTTTTGGAGCGCAGGGAGCGAGAGTGTGAA
CATGGCTACGCTTCATCATTCCCCTCCATGCCGAGCCCCCGGCTACAGCACTCAAAGCCCCCAC
GGAGGTTGAGCCGGGCACAGAAACACAGCAGTGGGAGCAGCAACACCAGCACTGCCAACAGATC
TACACACAATGAGTTGGAAAAGAATCGACGAGCTCACCTGCGCCTGTGTTTAGAACGCTTAAAA
GTTCTGATCCCGCTGGGCCCAGACTGCACCAGGCACACAACACTTGGTTTGCTCAACAAAGCCA
AAGCACACATCAAGAAACTTGAAGAAGCCGAAAGGAAGAGCCAGCACCAGCTTGAGAACTTGGA
ACGAGAACAGAGATTTTTAAAGCGGCGACTGGAACAGCTGCAGGGTCCTCAGGAGATGGAGCGG
ATACGAATGGACAGCATTGGATCAACGATCTCCTCAGATCGCTCGGATTCAGAGCGAGAGGAGA
TTGAAGTGGATGTGGAAAGCACAGAGTTCTCCCATGGAGAAGTGGACAACATCAGTACCACCAG
CATCAGCGACATCGATGACCACAGCAGCCTGCAGAGTATTGGGAGTGACGAGGGCTACTCCAGT
GCCAGTGTCAAACTCTCCTTCACGTCCTAGAACCCAGCATGACATAACAGTGCAGGGCGAAGTG
CTCACTGGGCCAGTTCAATACCGTCTCTCAAATTGGGTTCATGACGCAGTCTCCTCTTTAAAAC
TAAAAACTATACTTGAACAAAAGGGTCAGAAGACCTGTATTTAAGCAAATACTTAAAAAGTGGG
GTAGAGCCTCCCCGGTAGAACAAATACTCCTGTATTTGGAAAGAATACAGTTTCTAACAGCAGC
AGAAATGTGTGTGGTTATCTTGAGTTGACGTGGTTGACTTAAGAGACAATGGAGACTCCATTCT
CCTGTTGTAGTTTGCTCACTCCGTGTTGAGCAGACATTTAAGGATAGGGTTATGAACCCTTCCT
GAGCTTCTTGGTCCTAGAAACAAAATCAAACTTAGAGTAAGGAGAAGACAGGATAATCAGGCAT
TAATCTTGGATAGCTAAAGAGCTATTAAAACTCAGCCTCTGTGTATCATGAAGCCTGTGGATGA
TCAATTCTTTTAAAAAATGAATTTTTAAAAAGCTCATATCGTGCTCTACAAAAGGAGAGACTCC
CATGAAGCCTTTTGAACGAGATCATCATGCAGCTCAGCTTTCTGTTGGATTCCATGCTAAGCCA
GCTAACCTTACCTGCATTGATAGCACTAGAGCAGGCAAGCACCCGCTCGCCACCCTTCGGCCAC
GTAGGGGCAGCCCATGCATGACAGCCTGAATCACAGGAGGAACAGCTCCGTGTGCGAGCCTCGG
TGTCTGCGCGGATCTGAGGAGCTGTGCACGCAGTGTAGCAGGCCAAGGTCTGAGCCACCACAGC
ATTTTTATTTGAGATTTTGATAACTGTTTGTATGTGTTGAAAACCAAAATGACATCTTTTTAAA
GCTTGTCCATAAGTAAACATAGATGTCTTTTATAGTGGAATAAAACACGTGGGGGAAATCATCT
ATTTTGATGCAGCATTTGATAATGATAAACACCTCACGCCTCACTCTTTTCAGTGCGCAGGACG
GATGAGGTCTGGGCTGGGTAGACGAAGGCAATGCTGTTTTTGTTTTCTTTAGGACCATTCCCTT
TTACCAGCTTTTAACCGTCTGATACCCGTGGTAGGCACACTATCCTAGTTAACATAGTTATGTT
CCGCACTTGTCTCATTTAATGTAAAGATCTGCATTTTCTACAGGCAGTTTCCTCCCCACAATCC
CACTGTGCAGGTGCTACTGTTGCTCTCACAAATACCTGCAGAAATGTTATCTTCTGGGTGAGAC
TTCCAGCCCGCACTCCGTGTCATGTGCTCCCTCCTTTCAAACTCGAAGGTTTCCCTCTGGGCCA
CTGCTTTGCTCCGGGAAGCCTTTCTGGATACCTTACCCCAAGCTGTTCGGACTTTGTATTCTTT
AAATAATTTAACTACCCTTAATTACTTAAAAAAAAAAGCTTTATGATTTTCATAACTTATTGCC
GATTTTAATGGGTTGTTAATTTCAGTCCTGTAGTTTTATTTTATGTTTAGATAGGGCTGGGCAA
GGAGAAAGAAAATAAAAACAACCATATTCAGCAGTGCAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006231604 ⟹ XP_006231666

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	262,329,274 - 262,389,037 (+)	NCBI
mRatBN7.2	1	252,323,915 - 252,383,682 (+)	NCBI
Rnor_6.0	1	274,030,748 - 274,090,071 (+)	NCBI
Rnor_5.0	1	281,443,967 - 281,503,729 (+)	NCBI

Sequence:

show sequence

ATTTTTTTTTTCCATTCGTATTAAAGCACAGTGCTGTCTACGCAGTTAGGATTTGCGGAGAGGC
GGGGAAGGGTGCTGGGATAGGCAGAGGGCGGGCCCTGCCTCCCTAGCCGCCACCATTTATTTTG
ACCGGTCAGATGGCGACAGGCTCGCACTAGGACCCAGGCGCCACAGCGCCTCCGTCTGTCCTGT
AGGTTCATTCAATCTCCCATACACACAGATCCACACAGCGAGAGCGACACACACTCACACTCAC
AACCGCACGCAGCGAGGCTCGGCAAGTCAGGCCGGCTCCTTGCCCCGGCGCCTCCTCGGCTTCA
GCAGGCCGGATCTCCCAGGGGACCCGCAGCTCGGCCGGCTGCACAGCCCAGGACCAGGAGCAGC
TCGGCGGACCACCGTGCCTCCATGGGCAAACGCGGGCGGCCGCGCAAGGAGGCGCGCTGCGAGG
GCGCGGGGCTGGTCCCCGTCGCGCCCCCGGCCATGCCCCCGGCCGCGGCCGCGCCCCAGCCCCC
GGCGCAGCCCGAGGAGCCGGCGGGGGCCAAGCCCCGGTGCCCCTTCTCGGACATTTTCAACACC
AGCGAGAACTCGATGGAGAAGCACATCAACACTTTTCTGCAGAACGTGCAGATTCTGCTCGAGG
CAGCCAGCTACCTGGAGCAGATCGAGAAAGAAAACAAAAAGTGTGAACATGGCTACGCTTCATC
ATTCCCCTCCATGCCGAGCCCCCGGCTACAGCACTCAAAGCCCCCACGGAGGTTGAGCCGGGCA
CAGAAACACAGCAGTGGGAGCAGCAACACCAGCACTGCCAACAGATCTACACACAATGAGTTGG
AAAAGAATCGACGAGCTCACCTGCGCCTGTGTTTAGAACGCTTAAAAGTTCTGATCCCGCTGGG
CCCAGACTGCACCAGGCACACAACACTTGGTTTGCTCAACAAAGCCAAAGCACACATCAAGAAA
CTTGAAGAAGCCGAAAGGAAGAGCCAGCACCAGCTTGAGAACTTGGAACGAGAACAGAGATTTT
TAAAGCGGCGACTGGAACAGCTGCAGGGTCCTCAGGAGATGGAGCGGATACGAATGGACAGCAT
TGGATCAACGATCTCCTCAGATCGCTCGGATTCAGAGCGAGAGGAGATTGAAGTGGATGTGGAA
AGCACAGAGTTCTCCCATGGAGAAGTGGACAACATCAGTACCACCAGCATCAGCGACATCGATG
ACCACAGCAGCCTGCAGAGTATTGGGAGTGACGAGGGCTACTCCAGTGCCAGTGTCAAACTCTC
CTTCACGTCCTAGAACCCAGCATGACATAACAGTGCAGGGCGAAGTGCTCACTGGGCCAGTTCA
ATACCGTCTCTCAAATTGGGTTCATGACGCAGTCTCCTCTTTAAAACTAAAAACTATACTTGAA
CAAAAGGGTCAGAAGACCTGTATTTAAGCAAATACTTAAAAAGTGGGGTAGAGCCTCCCCGGTA
GAACAAATACTCCTGTATTTGGAAAGAATACAGTTTCTAACAGCAGCAGAAATGTGTGTGGTTA
TCTTGAGTTGACGTGGTTGACTTAAGAGACAATGGAGACTCCATTCTCCTGTTGTAGTTTGCTC
ACTCCGTGTTGAGCAGACATTTAAGGATAGGGTTATGAACCCTTCCTGAGCTTCTTGGTCCTAG
AAACAAAATCAAACTTAGAGTAAGGAGAAGACAGGATAATCAGGCATTAATCTTGGATAGCTAA
AGAGCTATTAAAACTCAGCCTCTGTGTATCATGAAGCCTGTGGATGATCAATTCTTTTAAAAAA
TGAATTTTTAAAAAGCTCATATCGTGCTCTACAAAAGGAGAGACTCCCATGAAGCCTTTTGAAC
GAGATCATCATGCAGCTCAGCTTTCTGTTGGATTCCATGCTAAGCCAGCTAACCTTACCTGCAT
TGATAGCACTAGAGCAGGCAAGCACCCGCTCGCCACCCTTCGGCCACGTAGGGGCAGCCCATGC
ATGACAGCCTGAATCACAGGAGGAACAGCTCCGTGTGCGAGCCTCGGTGTCTGCGCGGATCTGA
GGAGCTGTGCACGCAGTGTAGCAGGCCAAGGTCTGAGCCACCACAGCATTTTTATTTGAGATTT
TGATAACTGTTTGTATGTGTTGAAAACCAAAATGACATCTTTTTAAAGCTTGTCCATAAGTAAA
CATAGATGTCTTTTATAGTGGAATAAAACACGTGGGGGAAATCATCTATTTTGATGCAGCATTT
GATAATGATAAACACCTCACGCCTCACTCTTTTCAGTGCGCAGGACGGATGAGGTCTGGGCTGG
GTAGACGAAGGCAATGCTGTTTTTGTTTTCTTTAGGACCATTCCCTTTTACCAGCTTTTAACCG
TCTGATACCCGTGGTAGGCACACTATCCTAGTTAACATAGTTATGTTCCGCACTTGTCTCATTT
AATGTAAAGATCTGCATTTTCTACAGGCAGTTTCCTCCCCACAATCCCACTGTGCAGGTGCTAC
TGTTGCTCTCACAAATACCTGCAGAAATGTTATCTTCTGGGTGAGACTTCCAGCCCGCACTCCG
TGTCATGTGCTCCCTCCTTTCAAACTCGAAGGTTTCCCTCTGGGCCACTGCTTTGCTCCGGGAA
GCCTTTCTGGATACCTTACCCCAAGCTGTTCGGACTTTGTATTCTTTAAATAATTTAACTACCC
TTAATTACTTAAAAAAAAAAGCTTTATGATTTTCATAACTTATTGCCGATTTTAATGGGTTGTT
AATTTCAGTCCTGTAGTTTTATTTTATGTTTAGATAGGGCTGGGCAAGGAGAAAGAAAATAAAA
ACAACCATATTCAGCAGTGCA

hide sequence

RefSeq Acc Id:

XM_006231606 ⟹ XP_006231668

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	262,349,421 - 262,389,037 (+)	NCBI
mRatBN7.2	1	252,343,958 - 252,383,682 (+)	NCBI
Rnor_6.0	1	274,050,349 - 274,090,071 (+)	NCBI
Rnor_5.0	1	281,443,967 - 281,503,729 (+)	NCBI

Sequence:

show sequence

CGGGGGCGGAGTGGAGTGGGGGTAATGCCGGCTGAAGAGCTGCGGGAGGGGCTCCCTGCTATTG
TGAGCATGGGGTACAGTGAGATGGTGTTGCCTTGGAGGTGAAGATAGGTGGAGGAATAGGAAGA
CAGAGGAAGGAGTGTGAAGAGCCTAAATGCTGCTGTCAGGAGAGAGGAGGTCCTTACCGAGACG
TTGTGGTCAAAAGAGCTGGGGCACGCAAAAACGTTGAGGCTACAAAGGCACTGAAGAGAGTGTG
AACATGGCTACGCTTCATCATTCCCCTCCATGCCGAGCCCCCGGCTACAGCACTCAAAGCCCCC
ACGGAGGTTGAGCCGGGCACAGAAACACAGCAGTGGGAGCAGCAACACCAGCACTGCCAACAGA
TCTACACACAATGAGTTGGAAAAGAATCGACGAGCTCACCTGCGCCTGTGTTTAGAACGCTTAA
AAGTTCTGATCCCGCTGGGCCCAGACTGCACCAGGCACACAACACTTGGTTTGCTCAACAAAGC
CAAAGCACACATCAAGAAACTTGAAGAAGCCGAAAGGAAGAGCCAGCACCAGCTTGAGAACTTG
GAACGAGAACAGAGATTTTTAAAGCGGCGACTGGAACAGCTGCAGGGTCCTCAGGAGATGGAGC
GGATACGAATGGACAGCATTGGATCAACGATCTCCTCAGATCGCTCGGATTCAGAGCGAGAGGA
GATTGAAGTGGATGTGGAAAGCACAGAGTTCTCCCATGGAGAAGTGGACAACATCAGTACCACC
AGCATCAGCGACATCGATGACCACAGCAGCCTGCAGAGTATTGGGAGTGACGAGGGCTACTCCA
GTGCCAGTGTCAAACTCTCCTTCACGTCCTAGAACCCAGCATGACATAACAGTGCAGGGCGAAG
TGCTCACTGGGCCAGTTCAATACCGTCTCTCAAATTGGGTTCATGACGCAGTCTCCTCTTTAAA
ACTAAAAACTATACTTGAACAAAAGGGTCAGAAGACCTGTATTTAAGCAAATACTTAAAAAGTG
GGGTAGAGCCTCCCCGGTAGAACAAATACTCCTGTATTTGGAAAGAATACAGTTTCTAACAGCA
GCAGAAATGTGTGTGGTTATCTTGAGTTGACGTGGTTGACTTAAGAGACAATGGAGACTCCATT
CTCCTGTTGTAGTTTGCTCACTCCGTGTTGAGCAGACATTTAAGGATAGGGTTATGAACCCTTC
CTGAGCTTCTTGGTCCTAGAAACAAAATCAAACTTAGAGTAAGGAGAAGACAGGATAATCAGGC
ATTAATCTTGGATAGCTAAAGAGCTATTAAAACTCAGCCTCTGTGTATCATGAAGCCTGTGGAT
GATCAATTCTTTTAAAAAATGAATTTTTAAAAAGCTCATATCGTGCTCTACAAAAGGAGAGACT
CCCATGAAGCCTTTTGAACGAGATCATCATGCAGCTCAGCTTTCTGTTGGATTCCATGCTAAGC
CAGCTAACCTTACCTGCATTGATAGCACTAGAGCAGGCAAGCACCCGCTCGCCACCCTTCGGCC
ACGTAGGGGCAGCCCATGCATGACAGCCTGAATCACAGGAGGAACAGCTCCGTGTGCGAGCCTC
GGTGTCTGCGCGGATCTGAGGAGCTGTGCACGCAGTGTAGCAGGCCAAGGTCTGAGCCACCACA
GCATTTTTATTTGAGATTTTGATAACTGTTTGTATGTGTTGAAAACCAAAATGACATCTTTTTA
AAGCTTGTCCATAAGTAAACATAGATGTCTTTTATAGTGGAATAAAACACGTGGGGGAAATCAT
CTATTTTGATGCAGCATTTGATAATGATAAACACCTCACGCCTCACTCTTTTCAGTGCGCAGGA
CGGATGAGGTCTGGGCTGGGTAGACGAAGGCAATGCTGTTTTTGTTTTCTTTAGGACCATTCCC
TTTTACCAGCTTTTAACCGTCTGATACCCGTGGTAGGCACACTATCCTAGTTAACATAGTTATG
TTCCGCACTTGTCTCATTTAATGTAAAGATCTGCATTTTCTACAGGCAGTTTCCTCCCCACAAT
CCCACTGTGCAGGTGCTACTGTTGCTCTCACAAATACCTGCAGAAATGTTATCTTCTGGGTGAG
ACTTCCAGCCCGCACTCCGTGTCATGTGCTCCCTCCTTTCAAACTCGAAGGTTTCCCTCTGGGC
CACTGCTTTGCTCCGGGAAGCCTTTCTGGATACCTTACCCCAAGCTGTTCGGACTTTGTATTCT
TTAAATAATTTAACTACCCTTAATTACTTAAAAAAAAAAGCTTTATGATTTTCATAACTTATTG
CCGATTTTAATGGGTTGTTAATTTCAGTCCTGTAGTTTTATTTTATGTTTAGATAGGGCTGGGC
AAGGAGAAAGAAAATAAAAACAACCATATTCAGCAGTGCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001426860	(Get FASTA)	NCBI Sequence Viewer
	NP_001426861	(Get FASTA)	NCBI Sequence Viewer
	NP_037292	(Get FASTA)	NCBI Sequence Viewer
	XP_006231666	(Get FASTA)	NCBI Sequence Viewer
	XP_006231668	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB16960	(Get FASTA)	NCBI Sequence Viewer
	AAB61595	(Get FASTA)	NCBI Sequence Viewer
	AAH81824	(Get FASTA)	NCBI Sequence Viewer
	AAR95702	(Get FASTA)	NCBI Sequence Viewer
	EDL94419	(Get FASTA)	NCBI Sequence Viewer
	EDL94420	(Get FASTA)	NCBI Sequence Viewer
	EDL94421	(Get FASTA)	NCBI Sequence Viewer
	EDL94422	(Get FASTA)	NCBI Sequence Viewer
	EDL94423	(Get FASTA)	NCBI Sequence Viewer
	EDL94424	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000040770
	ENSRNOP00000067990
	ENSRNOP00000107728
GenBank Protein	O09015	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_037292 ⟸ NM_013160

- UniProtKB:

O09015 (UniProtKB/Swiss-Prot), Q642D1 (UniProtKB/TrEMBL), K3W4V2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MERVRMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNT
STANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQH
QLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVD
NISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS

hide sequence

RefSeq Acc Id:

XP_006231666 ⟸ XM_006231604

- Peptide Label:

isoform X1

- Sequence:

show sequence

MGKRGRPRKEARCEGAGLVPVAPPAMPPAAAAPQPPAQPEEPAGAKPRCPFSDIFNTSENSMEK
HINTFLQNVQILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGS
SNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERK
SQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHG
EVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS

hide sequence

RefSeq Acc Id:	XP_006231668 ⟸ XM_006231606
- Peptide Label:	isoform X2
- Sequence:	show sequence MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDC TRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKRRLEQLQGPQEMERIRMDSIGST ISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLQSIGSDEGYSSASVKLSFTS hide sequence

Ensembl Acc Id:

ENSRNOP00000040770 ⟸ ENSRNOT00000042822

Ensembl Acc Id:

ENSRNOP00000068001 ⟸ ENSRNOT00000076387

Ensembl Acc Id:

ENSRNOP00000067990 ⟸ ENSRNOT00000076779

Ensembl Acc Id:

ENSRNOP00000104233 ⟸ ENSRNOT00000169888

Ensembl Acc Id:

ENSRNOP00000107728 ⟸ ENSRNOT00000150550

Ensembl Acc Id:

ENSRNOP00000105405 ⟸ ENSRNOT00000165038

Protein Domains

bHLH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O09015-F1-model_v2	AlphaFold	O09015	1-228	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690991

Promoter ID:

EPDNEW_R1514

Type:

initiation region

Name:

Mxi1_2

Description:

MAX interactor 1, dimerization protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R1515

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	274,030,990 - 274,031,050	EPDNEW

RGD ID:

13690994

Promoter ID:

EPDNEW_R1515

Type:

initiation region

Name:

Mxi1_1

Description:

MAX interactor 1, dimerization protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R1514

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	274,049,545 - 274,049,605	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3128	AgrOrtholog
BioCyc Gene	G2FUF-55399	BioCyc
Ensembl Genes	ENSRNOG00000034078	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000042822	ENTREZGENE
	ENSRNOT00000076779	ENTREZGENE
	ENSRNOT00000150550	ENTREZGENE
Gene3D-CATH	4.10.280.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7133853	IMAGE-MGC_LOAD
InterPro	bHLH_dom	UniProtKB/Swiss-Prot
	HLH_DNA-bd_sf	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93544	IMAGE-MGC_LOAD
NCBI Gene	25701	ENTREZGENE
PANTHER	MAX DIMERIZATION, MAD	UniProtKB/Swiss-Prot
	MAX-INTERACTING PROTEIN 1	UniProtKB/Swiss-Prot
Pfam	HLH	UniProtKB/Swiss-Prot
PhenoGen	Mxi1	PhenoGen
PROSITE	BHLH	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000034078	RatGTEx
SMART	HLH	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47459	UniProtKB/Swiss-Prot
UniProt	A0A096MJ49_RAT	UniProtKB/TrEMBL
	A0A096MJ60	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L444_RAT	UniProtKB/TrEMBL
	A0ABK0LPN7_RAT	UniProtKB/TrEMBL
	A0ABK0LU07_RAT	UniProtKB/TrEMBL
	A6JHU5	ENTREZGENE, UniProtKB/TrEMBL
	A6JHU7_RAT	UniProtKB/TrEMBL
	A6JHU8_RAT	UniProtKB/TrEMBL
	A6JHU9	ENTREZGENE, UniProtKB/TrEMBL
	K3W4V2	ENTREZGENE, UniProtKB/TrEMBL
	MXI1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	P70542_RAT	UniProtKB/TrEMBL
	Q642D1	ENTREZGENE, UniProtKB/TrEMBL
	Q6RKA6_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-29	Mxi1	MAX interactor 1, dimerization protein	LOC100360467	Max interactor 1-like	Data merged from RGD:2322089	737654	PROVISIONAL
2013-04-12	Mxi1	MAX interactor 1, dimerization protein	LOC100360898	Max interactor 1-like	Data merged from RGD:2321260	737654	PROVISIONAL
2012-11-21	Mxi1	MAX interactor 1, dimerization protein	Mxi1	MAX interactor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-06	LOC100360467	Max interactor 1-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2010-05-05	LOC100360898	Max interactor 1-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-09-09	Mxi1	MAX interactor 1	Mxi1	Max interacting protein 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Mxi1	max interacting protein 1			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_process	regulates Myc oncoprotein activity thus playing an important role in proliferation, differentiation, and apoptosis	70302

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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