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Gene: Itpkb (inositol-trisphosphate 3-kinase B) Rattus norvegicus

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Symbol:

Itpkb

Name:

inositol-trisphosphate 3-kinase B

RGD ID:

2932

Description:

Predicted to enable inositol hexakisphosphate kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. Predicted to be involved in cellular response to calcium ion; inositol phosphate metabolic process; and phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within several processes, including common myeloid progenitor cell proliferation; negative regulation of neutrophil apoptotic process; and regulation of hemopoiesis. Predicted to be located in several cellular components, including cytoskeleton; cytosol; and endoplasmic reticulum. Predicted to be active in cytoplasm and nucleus. Orthologous to human ITPKB (inositol-trisphosphate 3-kinase B); PARTICIPATES IN calcium/calcium-mediated signaling pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

inositol 1,4,5-trisphosphate 3-kinase B; insP 3-kinase B; IP3 3-kinase B; IP3K B; IP3K-B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ITPKB (inositol-trisphosphate 3-kinase B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Itpkb (inositol 1,4,5-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Itpkb (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ITPKB (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ITPKB (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Itpkb (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ITPKB (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ITPKB (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Itpkb (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Itpkb (inositol-trisphosphate 3-kinase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ITPKB (inositol-trisphosphate 3-kinase B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Itpkb (inositol 1,4,5-trisphosphate 3-kinase B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	itpkb (inositol-trisphosphate 3-kinase B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	itpkb (inositol-trisphosphate 3-kinase B)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lfe-2	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	IP3K2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	IP3K2	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	itpkb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	itpkb	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	94,601,072 - 94,696,180 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	94,601,167 - 94,696,179 (+)	Ensembl				GRCr8
mRatBN7.2	13	92,069,160 - 92,164,281 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	92,069,216 - 92,162,004 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	94,574,383 - 94,667,140 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	95,974,568 - 96,067,342 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	93,149,283 - 93,242,066 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	98,615,287 - 98,710,426 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	98,615,287 - 98,708,149 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	103,624,308 - 103,716,372 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	96,044,260 - 96,138,456 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	91,617,603 - 91,709,915 (+)	NCBI		Celera
RGSC_v3.1	13	96,235,230 - 96,327,084 (+)	NCBI
RH 3.4 Map	13	629.9	RGD
Cytogenetic Map	13	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

myeloproliferative neoplasm (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

8-Br-cAMP (ISO)

acetamide (EXP)

acrolein (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-naphthoflavone (EXP)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Brodifacoum (EXP)

cadmium dichloride (ISO)

cefaloridine (EXP)

chlordecone (ISO)

chlorpyrifos (ISO)

choline (ISO)

cocaine (EXP)

copper atom (EXP)

copper(0) (EXP)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

GSK-J4 (ISO)

isoprenaline (ISO)

L-methionine (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-ethyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP,ISO)

nicotine (EXP)

nitrofen (EXP)

ochratoxin A (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sunitinib (ISO)

testosterone (EXP)

tetrachloromethane (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

tungsten (ISO)

valproic acid (ISO)

vincristine (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface receptor signaling pathway (ISO)

cellular response to calcium ion (IEA,ISO,ISS)

common myeloid progenitor cell proliferation (ISO)

inositol phosphate biosynthetic process (IBA,IEA)

inositol trisphosphate metabolic process (IEA,ISO,ISS)

MAPK cascade (ISO)

myeloid cell homeostasis (ISO)

negative regulation of myeloid cell differentiation (ISO)

negative regulation of neutrophil apoptotic process (ISO)

phosphatidylinositol phosphate biosynthetic process (IBA,IEA,ISO,ISS)

positive regulation of alpha-beta T cell differentiation (ISO)

positive regulation of Ras protein signal transduction (ISO)

positive thymic T cell selection (ISO)

regulation of protein phosphorylation (ISO)

T cell differentiation (ISO)

thymic T cell selection (ISO)

Cellular Component

cytoplasm (IBA,IEA,ISO,ISS)

cytoskeleton (IEA,ISO,ISS)

cytosol (IEA,ISO)

endoplasmic reticulum (IEA,ISO,ISS)

membrane (IEA,ISO)

nucleus (IBA,IEA,ISO)

Molecular Function

ATP binding (IEA)

calmodulin binding (IEA)

inositol hexakisphosphate kinase activity (IBA)

inositol-1,4,5-trisphosphate 3-kinase activity (IEA,ISO,ISS)

kinase activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium/calcium-mediated signaling pathway (IEA)

inositol phosphate metabolic pathway (IEA)

phosphatidylinositol 3-kinase signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Isolation and sequence of a full length cDNA encoding a novel rat inositol 1,4,5-trisphosphate 3-kinase.	Thomas S, etal., Biochim Biophys Acta 1994 Jan 13;1220(2):219-22.
9.	KRP3A and KRP3B: candidate motors in spermatid maturation in the seminiferous epithelium.	Zou Y, etal., Biol Reprod 2002 Mar;66(3):843-55.

Additional References at PubMed

PMID:1654894	PMID:8889548	PMID:14517551	PMID:15064401	PMID:15381088	PMID:16173920	PMID:18339802

Genomics

Comparative Map Data

Itpkb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	94,601,072 - 94,696,180 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	94,601,167 - 94,696,179 (+)	Ensembl				GRCr8
mRatBN7.2	13	92,069,160 - 92,164,281 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	92,069,216 - 92,162,004 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	94,574,383 - 94,667,140 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	95,974,568 - 96,067,342 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	93,149,283 - 93,242,066 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	98,615,287 - 98,710,426 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	98,615,287 - 98,708,149 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	103,624,308 - 103,716,372 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	96,044,260 - 96,138,456 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	91,617,603 - 91,709,915 (+)	NCBI		Celera
RGSC_v3.1	13	96,235,230 - 96,327,084 (+)	NCBI
RH 3.4 Map	13	629.9	RGD
Cytogenetic Map	13	q26	NCBI

ITPKB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	226,631,690 - 226,739,282 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	226,631,688 - 226,739,323 (-)	Ensembl			hg38	GRCh38
GRCh37	1	226,819,391 - 226,926,983 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	224,886,014 - 224,991,818 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	1	223,126,126 - 223,231,930	NCBI
Celera	1	200,010,306 - 200,117,787 (-)	NCBI		Celera
Cytogenetic Map	1	q42.12	NCBI
HuRef	1	197,336,497 - 197,443,479 (-)	NCBI		HuRef
CHM1_1	1	228,092,188 - 228,199,660 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	225,819,873 - 225,927,469 (-)	NCBI		T2T-CHM13v2.0

Itpkb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	180,156,655 - 180,252,367 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	180,158,050 - 180,252,367 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	180,330,390 - 180,424,802 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	180,330,485 - 180,424,802 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	182,260,607 - 182,353,790 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	182,167,151 - 182,260,334 (+)	NCBI		MGSCv36	mm8
Celera	1	187,393,960 - 187,488,842 (+)	NCBI		Celera
Cytogenetic Map	1	H4	NCBI
cM Map	1	84.27	NCBI

Itpkb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955489	725,759 - 814,180 (-)	Ensembl
ChiLan1.0	NW_004955489	726,641 - 814,180 (-)	NCBI	ChiLan1.0	ChiLan1.0

ITPKB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	22,799,337 - 22,907,636 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	22,747,787 - 22,856,066 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	202,091,263 - 202,198,880 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	207,084,883 - 207,191,692 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	207,084,883 - 207,191,678 (-)	Ensembl			panPan2	panpan1.1

ITPKB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	38,253,257 - 38,346,400 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	38,253,407 - 38,343,345 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	37,736,914 - 37,828,383 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	38,089,021 - 38,180,423 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	38,087,507 - 38,185,299 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	37,928,053 - 38,019,442 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	37,935,010 - 38,026,325 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	38,205,654 - 38,297,131 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Itpkb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	51,270,129 - 51,387,160 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	3,376,786 - 3,477,554 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	3,378,046 - 3,477,177 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ITPKB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	10	14,362,883 - 14,469,586 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	16,758,349 - 16,763,114 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ITPKB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	3,009,464 - 3,117,729 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	3,009,353 - 3,118,235 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	3,015,041 - 3,123,072 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Itpkb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624807	658,231 - 741,195 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624807	658,334 - 741,018 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Itpkb
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	58,661,976 - 58,757,915 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Itpkb
834 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	95
Count of miRNA genes:	67
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000004032
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

RH94654

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	92,161,481 - 92,161,643 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,707,627 - 98,707,788	NCBI	Rnor6.0
Rnor_5.0	13	103,715,849 - 103,716,010	UniSTS	Rnor5.0
RGSC_v3.4	13	96,137,933 - 96,138,094	UniSTS	RGSC3.4
Celera	13	91,709,392 - 91,709,553	UniSTS
RH 3.4 Map	13	629.9	UniSTS
Cytogenetic Map	13	q26	UniSTS

RH94655

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	94,603,422 - 94,603,620 (+)	Marker Load Pipeline
mRatBN7.2	13	92,071,488 - 92,071,686 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,617,558 - 98,617,755	NCBI	Rnor6.0
Rnor_5.0	13	103,626,580 - 103,626,777	UniSTS	Rnor5.0
RGSC_v3.4	13	96,046,532 - 96,046,729	UniSTS	RGSC3.4
Celera	13	91,619,874 - 91,620,071	UniSTS
Cytogenetic Map	13	q26	UniSTS

BE113255

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	92,161,840 - 92,162,001 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,707,986 - 98,708,146	NCBI	Rnor6.0
Rnor_5.0	13	103,716,208 - 103,716,368	UniSTS	Rnor5.0
RGSC_v3.4	13	96,138,292 - 96,138,452	UniSTS	RGSC3.4
Celera	13	91,709,751 - 91,709,911	UniSTS
RH 3.4 Map	13	628.6	UniSTS
Cytogenetic Map	13	q26	UniSTS

BE120603

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	92,141,586 - 92,141,750 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,687,732 - 98,687,895	NCBI	Rnor6.0
Rnor_5.0	13	103,696,667 - 103,696,830	UniSTS	Rnor5.0
RGSC_v3.4	13	96,118,376 - 96,118,539	UniSTS	RGSC3.4
Celera	13	91,689,905 - 91,690,068	UniSTS
RH 3.4 Map	13	620.0	UniSTS
Cytogenetic Map	13	q26	UniSTS

AU047843

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	94,601,942 - 94,602,090 (+)	Marker Load Pipeline
mRatBN7.2	13	92,070,008 - 92,070,156 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,616,080 - 98,616,225	NCBI	Rnor6.0
Rnor_5.0	13	103,625,100 - 103,625,247	NCBI	Rnor5.0
RGSC_v3.4	13	96,045,053 - 96,045,198	UniSTS	RGSC3.4
Celera	13	91,618,396 - 91,618,541	UniSTS
Cytogenetic Map	13	q26	UniSTS

RH140655

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	92,069,271 - 92,069,451 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,615,343 - 98,615,522	NCBI	Rnor6.0
Rnor_5.0	13	103,624,364 - 103,624,543	UniSTS	Rnor5.0
RGSC_v3.4	13	96,044,316 - 96,044,495	UniSTS	RGSC3.4
Celera	13	91,617,659 - 91,617,838	UniSTS
RH 3.4 Map	13	630.3	UniSTS
Cytogenetic Map	13	q26	UniSTS

AW529865

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	92,147,165 - 92,147,336 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,693,311 - 98,693,481	NCBI	Rnor6.0
Rnor_5.0	13	103,702,246 - 103,702,416	UniSTS	Rnor5.0
RGSC_v3.4	13	96,123,955 - 96,124,125	UniSTS	RGSC3.4
Celera	13	91,695,484 - 91,695,654	UniSTS
RH 3.4 Map	13	618.2	UniSTS
Cytogenetic Map	13	q26	UniSTS

UniSTS:234290

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	92,069,242 - 92,069,463 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	98,615,314 - 98,615,534	NCBI	Rnor6.0
Rnor_5.0	13	103,624,335 - 103,624,555	UniSTS	Rnor5.0
RGSC_v3.4	13	96,044,287 - 96,044,507	UniSTS	RGSC3.4
Celera	13	91,617,630 - 91,617,850	UniSTS
Cytogenetic Map	13	q26	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	162	91	90	59	92	59	6	356	192	11	141	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA859368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC128915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ242781	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE113255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF418570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X74227	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004032 ⟹ ENSRNOP00000004032

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	94,601,167 - 94,696,179 (+)	Ensembl
mRatBN7.2 Ensembl	13	92,069,216 - 92,162,004 (+)	Ensembl
Rnor_6.0 Ensembl	13	98,615,287 - 98,708,149 (+)	Ensembl

RefSeq Acc Id:

NM_019312 ⟹ NP_062185

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	94,601,150 - 94,693,904 (+)	NCBI
mRatBN7.2	13	92,069,216 - 92,162,005 (+)	NCBI
Rnor_6.0	13	98,615,287 - 98,708,150 (+)	NCBI
Rnor_5.0	13	103,624,308 - 103,716,372 (+)	NCBI
RGSC_v3.4	13	96,044,260 - 96,138,456 (+)	RGD
Celera	13	91,617,603 - 91,709,915 (+)	RGD

Sequence:

show sequence

TTTTAAATCTTACATTGAACAAACACTGAAGTAGCCGGGAGCAGACGCTGACAGCAGTAGTGTC
TCCAACCAAGCACGGAGCAGCGCACGACCTGGCGGTGTCCCCTACGGGATCGCCTAGTCCCTGC
GCCGGTACATTCAGCCTCGTTGCACCCCACTATTTTCGTCTTCCAAAAGTTGTTGCGGAAACCC
TTTGGGGGCTTTTTTTTTTAACTTTAAGCCACCTGGTCTGTACGAGCCCGGAGTCCCCGGGGCA
TGTCGCCTGCACAGGACCTGGGAGTCTGAGCAATTGCAGCCGCGAAATCGTTTATGGAGCTTGG
CGCGGGGGCCAAGCCTGAGATCTTGCCCCGTGCCCGCCGCCTAGGCCATGCTGCTCCATCGGCG
CGCGGAGCTGCGGCCGCCGGGCCTCCAGGACTAAGCCGGGAGCCGCGGGAGGAGGAGGCGCCGG
CGGTGGAGCGGGACCGAGAGCCGCGGCGGCGGGCGGACCCAGTACTATGGCTGTGTACTGCTAT
GCCCTCAATAGCCTGGTGATCATGAACAGCACCAACGAGCTGAAGAGTGGCAGCCCCCTGCCCA
GCGGCAGCGAAACGCCTCAGCCCTCCGGGAGGGCCGCGCTGAGCCCCGGCAGCGTCTTCAGCCC
TGGGAGAGGCGCCTCCTTTCTCTTCCCCCCAGCAGAGTCGCTGTCGCTGGAGGAGCCTGGGAGT
GCTGGGGGTTGGCGCAGCGGCCGACGGAGGCTGAATAGTAGCAGCGGTAGCGGAGGTGGCAGCA
GCAGCAGCAACAGCAGCAGCAGCAGTGGCGTGGGCAGTCCCAGTTGGGCTGGCCGCCTGCGAGG
GGACGCGCAGCAGGTGGTGGCGACCCGCATCCTCTCCCCACCTGGGCCGGAGGAGGCCCAGAGG
AAGCTGAGGATTCTGCAGCGCGAATTGCAAAATGTGCAGGTGAACCAGAAAGTGGGCATGTTCG
AGGCGCAAATCCAGGCACAGACCTCTGCTATTCAAGCGCCCCGAAGCCCGCGTTTGGGTAGGGC
TCGTTCGCCCTCCCCGTGTCCCTTCCGAAGCAGCAGCCAGCCTCCTGAAAGGGTCTTGGCTCCA
TGTTCCCCAAGTGAGGAACGGAGAACAAAGTCCTGGGGAGAACAATGTACAGAGACCCCAGATG
CCAACTCCAGGAGGAGAAGCAGACTCAGCACACACCCCTCGAAGGACAAGGAGGGAGTGGCCCC
TCTTTTAGGCCCAGCCAGCCCGACCAGGTTAGGGACTCAGAGTCCATCTACTTCAGTGAGAATG
GAAAGAGGTTCCCCGGCCAGTCCCCGCTGTGGCTCACCCACACCCATGGAAATTGACAAGAGGA
CTGCTCCCTCACTGGAGCACTTTGGGACTAGCTTAACGTTGGCCACTAAAGTGGCAGCTTCGGC
CGCATCCGCTGGACCACACCCTGGACATGATTCTGTTCTCATGGAGGCAGACTGTGAGCTAGGG
GCCATGCGCCCCTGGGAGGCCCACCTGGAGAGACGGGGGCAGTTTCTGGGCAGGGAGACCGGCT
CAGCCCCAGAGCCTATCCGGACCCACATTAGAGAACCCCCTGGAAGGGTGGAAAGAGTTCATTC
TGTTGGTGGCCAGGGCTCCTGGACACCTGAAGTCATCAAAAGACCAGAAGAGGGAACTGTGGAT
GCCCAAAGCTCAGAGCTCTCAGAGAACCCGAGATGGTCTAGACTGCCTGGAGACCCGGGTTCCG
TAGGGCCTGAGAAGGGAGGTAGTAGGATCCCAGGAATCCGAGGACCCCAGCAGACCCTGGACAG
CATGAGAGAAGGGTCTTCAGCACTGGGCTTGCTTGGGGGCAGCCAGGCAGCACAGCCAGGGAGC
ATGGATGTGGAGACAGGCATTAGTTGTGGCAGAATGCTGGAACCCTTACCACCTGGGGAAGTAA
CAACAAATTTGAAAGAACCCCAGTGCCTCCCTGGGGACAGGATGGGGATGCAGCCTGAGAGTTC
CATAGTTTGGCCCAGTGCTGTGGAGGAAGCTCCCCTGATCTGGACGTGTGACACAGGGATACAG
TTAAAGGGGACTTGGAGAAGCCAAGATGGAGATGCTCATCCTAGCTGCCAAGAGAAGTCCCCAG
ACCAGAAGGACAAGGCCTGCAGCCCCAGCAACATCCCGGCCATCCCTGCAGTCATCATTACAGA
TATGGGTGCTCAGGAGGATGGAGGGTTAGAGGAGATCCAAGGAAGCCCTCGGGGTCCCCTGCCT
CTGAGGAAGCTGTCGTCCTCCTCAGCCTCCTCCACTGGCTTCTCCTCTTCCTATGAGGACTCGG
AGGAGGACATCTCCAGTGACCCTGAGCGCACTCTGGACCCCAACTCAGCCTTTTTGCATACCTT
GGACCAGCAGAAGCCCAGAGTGAGCAAGTCATGGAGGAAGATAAAGAACATGGTGCAGTGGTCC
CCCTTTGTCATGTCCTTCAAGAAGAAGTACCCCTGGATCCAGCTGGCAGGACATGCAGGGAGCT
TCAAGGCAGCTGCGAATGGCCGTATCCTTAAGAAGCATTGTGAGTCTGAACAGCGATGCCTGGA
CCGGTTAATGGCGGATGTGCTGAGGCCCTTCGTGCCAGCCTACCATGGCGACGTGGTGAAGGAC
GGGGAACGCTACAACCAGATGGACGACCTGCTGGCTGACTTCGATTCACCCTGCGTGATGGACT
GCAAGATGGGCATCAGGACATACCTGGAGGAAGAACTCACCAAGGCCCGGAAGAAGCCTAGCTT
GCGGAAGGACATGTACCAGAAGATGGTGGAGGTGGACCCTGAGGCCCCCACTGAAGAGGAGAAA
GCCCAGAGAGCTGTGACCAAGCCACGTTATATGCAGTGGCGGGAAACCATCAGTTCCACAGCTA
CCTTAGGCTTCAGGATCGAGGGCATCAAGAAGGAAGATGGCTCTGTGAACCGTGACTTCAAGAA
GACCAAAACAAGGGAGCAGGTCACTGAGGCCTTCAGAGAATTCACTAAAGGAAACCAGAACATC
CTGATTGCCTACCGGGACCGGTTGAAGGCCATTCGAGAAACCCTGGAAGTCTCTCCCTTCTTCA
AGTGCCATGAGGTCATTGGCAGCTCTCTCCTCTTCATCCACGACAAGAAGGAGCAAGCCAAGGT
GTGGATGATTGACTTTGGGAAAACCACGCCCCTTCCGGAAGGCCAGACCCTACAACACGATGTC
CCCTGGCAGGAGGGGAACCGGGAGGATGGCTACCTCTCAGGGCTGAACAACCTCATCGACATCC
TGACAGAAATGTCCCAGGGCAGCCCACTCACCTGAGGCCACCAGCACCTTGCATAGCCATGCCA
CCTTGCCCGCCACCTCTGCCTGTCGCAGCATCTCTCTTCCCCTGATTCTTCTTCCTTTTCCTGT
CTGAGCGCCTACCTAGAACAGAGCCTCCCATCTGCACTACAGGACACTTTGGAGAAGAGAAGAG
AGATTTTTTTTTCTAGGTCTTTATCTCCCGCCTTCCTACACAGGGGCCTGGAGGTGGCGTTTCT
AATTCTCTCTAAATAGAACTACCTTCTAGAAGAGAATTGCACAGAGCTAGGCCCCCGCATCCCG
TTACACTTAGAGCCTGCACGGGTCTAGAAGGCTGTGGGATCCCTGGCTGCCTAGGGTCTTAAGA
GATTGAGCCTCCCTCCCAGAGACCCTCCCGCCCCGCACCCCTCACCCCCCACTCCCGAGAAAGT
TCTGGCCCACATTGGCTACCAGTGGAGGCCTTCTGCCCCCTGGTGGCTGGTGCCATAAGTAAAC
ACAGTCCCATTCGTGCCTCCTACCATGGACCCTGAAGCTAGGGTCCTGCTTTCTGGAAGTTGGG
AAGCCAATCTCTGGGGGATCTGCGTGTGGCTTATGAGAAAAGTCTCCTGCAGTTAGAAGCCCCA
GCTCCCAAATACACCGTGTGGCTTCTCTCGAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039091025 ⟹ XP_038946953

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	94,601,072 - 94,681,735 (+)	NCBI
mRatBN7.2	13	92,069,160 - 92,148,680 (+)	NCBI

RefSeq Acc Id:

XM_039091026 ⟹ XP_038946954

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	94,641,149 - 94,696,180 (+)	NCBI
mRatBN7.2	13	92,117,707 - 92,164,281 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_062185	(Get FASTA)	NCBI Sequence Viewer
	XP_038946953	(Get FASTA)	NCBI Sequence Viewer
	XP_038946954	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAA52298	(Get FASTA)	NCBI Sequence Viewer
	CAC40660	(Get FASTA)	NCBI Sequence Viewer
	EDL94824	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004032
	ENSRNOP00000004032.5
GenBank Protein	P42335	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_062185 ⟸ NM_019312

- UniProtKB:

Q91XW1 (UniProtKB/Swiss-Prot), P42335 (UniProtKB/Swiss-Prot), A6JGG8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVYCYALNSLVIMNSTNELKSGSPLPSGSETPQPSGRAALSPGSVFSPGRGASFLFPPAESLS
LEEPGSAGGWRSGRRRLNSSSGSGGGSSSSNSSSSSGVGSPSWAGRLRGDAQQVVATRILSPPG
PEEAQRKLRILQRELQNVQVNQKVGMFEAQIQAQTSAIQAPRSPRLGRARSPSPCPFRSSSQPP
ERVLAPCSPSEERRTKSWGEQCTETPDANSRRRSRLSTHPSKDKEGVAPLLGPASPTRLGTQSP
STSVRMERGSPASPRCGSPTPMEIDKRTAPSLEHFGTSLTLATKVAASAASAGPHPGHDSVLME
ADCELGAMRPWEAHLERRGQFLGRETGSAPEPIRTHIREPPGRVERVHSVGGQGSWTPEVIKRP
EEGTVDAQSSELSENPRWSRLPGDPGSVGPEKGGSRIPGIRGPQQTLDSMREGSSALGLLGGSQ
AAQPGSMDVETGISCGRMLEPLPPGEVTTNLKEPQCLPGDRMGMQPESSIVWPSAVEEAPLIWT
CDTGIQLKGTWRSQDGDAHPSCQEKSPDQKDKACSPSNIPAIPAVIITDMGAQEDGGLEEIQGS
PRGPLPLRKLSSSSASSTGFSSSYEDSEEDISSDPERTLDPNSAFLHTLDQQKPRVSKSWRKIK
NMVQWSPFVMSFKKKYPWIQLAGHAGSFKAAANGRILKKHCESEQRCLDRLMADVLRPFVPAYH
GDVVKDGERYNQMDDLLADFDSPCVMDCKMGIRTYLEEELTKARKKPSLRKDMYQKMVEVDPEA
PTEEEKAQRAVTKPRYMQWRETISSTATLGFRIEGIKKEDGSVNRDFKKTKTREQVTEAFREFT
KGNQNILIAYRDRLKAIRETLEVSPFFKCHEVIGSSLLFIHDKKEQAKVWMIDFGKTTPLPEGQ
TLQHDVPWQEGNREDGYLSGLNNLIDILTEMSQGSPLT

hide sequence

Ensembl Acc Id:

ENSRNOP00000004032 ⟸ ENSRNOT00000004032

RefSeq Acc Id:	XP_038946953 ⟸ XM_039091025
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038946954 ⟸ XM_039091026
- Peptide Label:	isoform X2

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P42335-F1-model_v2	AlphaFold	P42335	1-934	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699058

Promoter ID:

EPDNEW_R9583

Type:

initiation region

Name:

Itpkb_1

Description:

inositol-trisphosphate 3-kinase B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	98,615,342 - 98,615,402	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2932	AgrOrtholog
BioCyc Gene	G2FUF-17127	BioCyc
BioCyc Pathway	PWY-6361 [1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)]	BioCyc
	PWY-6362 [1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)]	BioCyc
	PWY-6364 [D-myo-inositol (1,3,4)-trisphosphate biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-6361	BioCyc
	PWY-6362	BioCyc
	PWY-6364	BioCyc
Ensembl Genes	ENSRNOG00000002969	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000004032	ENTREZGENE
	ENSRNOT00000004032.7	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.470.160	UniProtKB/Swiss-Prot
InterPro	IPK	UniProtKB/Swiss-Prot
	IPK_sf	UniProtKB/Swiss-Prot
KEGG Report	rno:54260	UniProtKB/Swiss-Prot
NCBI Gene	54260	ENTREZGENE
PANTHER	INOSITOL-TRISPHOSPHATE 3-KINASE B	UniProtKB/Swiss-Prot
	PTHR12400	UniProtKB/Swiss-Prot
Pfam	IPK	UniProtKB/Swiss-Prot
PhenoGen	Itpkb	PhenoGen
RatGTEx	ENSRNOG00000002969	RatGTEx
Superfamily-SCOP	SAICAR synthase-like	UniProtKB/Swiss-Prot
UniProt	A6JGG8	ENTREZGENE, UniProtKB/TrEMBL
	IP3KB_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q91XW1	ENTREZGENE
UniProt Secondary	Q91XW1	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-02	Itpkb	inositol-trisphosphate 3-kinase B	Itpkb	inositol 1,4,5-trisphosphate 3-kinase B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Itpkb	Inositol 1,4,5-trisphosphate 3-kinase B			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_homology	93% identical to the human gene	633051

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways

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Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

BioCyc Pathways