Hmmr (hyaluronan-mediated motility receptor) - Rat Genome Database

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Gene: Hmmr (hyaluronan-mediated motility receptor) Rattus norvegicus
Analyze
Symbol: Hmmr
Name: hyaluronan-mediated motility receptor
RGD ID: 2805
Description: Predicted to enable cargo receptor activity. Predicted to be involved in hyaluronan catabolic process and receptor-mediated endocytosis. Predicted to be located in cytoplasm and spindle. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human HMMR (hyaluronan mediated motility receptor); PARTICIPATES IN cell-extracellular matrix signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hyaluronan mediated motility receptor; hyaluronan mediated motility receptor (RHAMM); intracellular hyaluronic acid-binding protein; receptor for hyaluronan-mediated motility; RHAMM
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,635,249 - 25,665,389 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1025,635,915 - 25,665,390 (-)EnsemblGRCr8
mRatBN7.21025,132,933 - 25,163,029 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,132,977 - 25,163,060 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1029,896,163 - 29,925,311 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,384,690 - 29,413,838 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,871,353 - 24,900,499 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,861,490 - 25,890,639 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,861,490 - 25,890,639 (-)Ensemblrn6Rnor6.0
Rnor_5.01025,712,357 - 25,740,811 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41025,733,375 - 25,762,825 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1024,693,386 - 24,722,348 (-)NCBICelera
RGSC_v3.11025,734,423 - 25,763,874 (-)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-diaminotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (ISO)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antimycin A  (ISO)
aristolochic acid A  (EXP)
arsenite(3-)  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
brequinar  (ISO)
buta-1,3-diene  (ISO)
cadmium dichloride  (EXP,ISO)
calcipotriol  (ISO)
calcitriol  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
cordycepin  (ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
DDE  (ISO)
deguelin  (ISO)
diallyl trisulfide  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
diethyl malate  (ISO)
dimethylarsinous acid  (ISO)
dimethylselenide  (ISO)
dioxygen  (EXP)
doxorubicin  (EXP,ISO)
Enterolactone  (ISO)
erythromycin estolate  (EXP)
ethanol  (ISO)
flavonoids  (EXP)
formaldehyde  (ISO)
fructose  (ISO)
glucose  (ISO)
glyphosate  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
kojic acid  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
levonorgestrel  (ISO)
lidocaine  (EXP)
lucanthone  (ISO)
mercury dichloride  (EXP)
Mesaconitine  (EXP)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylphenidate  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monoethyl phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-Nitrosopyrrolidine  (ISO)
niclosamide  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
senecionine  (EXP)
Senkirkine  (EXP)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (ISO)
tetrathiomolybdate(2-)  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
tremolite asbestos  (ISO)
tributylstannane  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
verteporfin  (ISO)
vincaleukoblastine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IEA)
centrosome  (IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA,ISO)
microtubule cytoskeleton  (IEA,ISO)
spindle  (IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
2. Identification of sequence, protein isoforms, and distribution of the hyaluronan-binding protein RHAMM in adult and developing rat brain. Lynn BD, etal., J Comp Neurol 2001 Oct 22;439(3):315-30.
3. Sequence, protein expression and extracellular-regulated kinase association of the hyaladherin RHAMM (receptor for hyaluronan mediated motility) in PC12 cells. Lynn BD, etal., Neurosci Lett 2001 Jun 22;306(1-2):49-52.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:16037485   PMID:19946888   PMID:21281821   PMID:23768790   PMID:25253654   PMID:28217782  


Genomics

Comparative Map Data
Hmmr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81025,635,249 - 25,665,389 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1025,635,915 - 25,665,390 (-)EnsemblGRCr8
mRatBN7.21025,132,933 - 25,163,029 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1025,132,977 - 25,163,060 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1029,896,163 - 29,925,311 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01029,384,690 - 29,413,838 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01024,871,353 - 24,900,499 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01025,861,490 - 25,890,639 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1025,861,490 - 25,890,639 (-)Ensemblrn6Rnor6.0
Rnor_5.01025,712,357 - 25,740,811 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41025,733,375 - 25,762,825 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1024,693,386 - 24,722,348 (-)NCBICelera
RGSC_v3.11025,734,423 - 25,763,874 (-)NCBI
Cytogenetic Map10q12NCBI
HMMR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385163,460,632 - 163,491,941 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5163,460,203 - 163,491,945 (+)Ensemblhg38GRCh38
GRCh375162,887,638 - 162,918,947 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365162,820,241 - 162,851,525 (+)NCBIBuild 36Build 36hg18NCBI36
Build 345162,820,240 - 162,851,523NCBI
Celera5158,921,625 - 158,953,052 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5157,987,202 - 158,018,630 (+)NCBIHuRef
CHM1_15162,319,984 - 162,351,413 (+)NCBICHM1_1
T2T-CHM13v2.05163,995,809 - 164,027,111 (+)NCBIT2T-CHM13v2.0
Hmmr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391140,592,215 - 40,624,290 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1140,592,222 - 40,624,249 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381140,701,388 - 40,733,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1140,701,395 - 40,733,422 (-)Ensemblmm10GRCm38
MGSCv371140,514,890 - 40,546,939 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361140,545,177 - 40,576,845 (-)NCBIMGSCv36mm8
Celera1144,551,316 - 44,585,491 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.4NCBI
Hmmr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540816,865,175 - 16,898,328 (+)Ensembl
ChiLan1.0NW_00495540816,865,066 - 16,895,918 (+)NCBIChiLan1.0ChiLan1.0
HMMR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24158,633,386 - 158,665,136 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15156,772,932 - 156,804,681 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05158,837,511 - 158,868,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15165,614,127 - 165,645,478 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5165,614,127 - 165,645,478 (+)EnsemblpanPan2panpan1.1
HMMR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1447,743,576 - 47,786,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl447,744,433 - 47,786,987 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha447,636,932 - 47,680,143 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0448,174,453 - 48,217,932 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl448,173,528 - 48,218,336 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1447,957,849 - 48,001,109 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0448,116,318 - 48,159,393 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0448,635,989 - 48,679,214 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Hmmr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213102,120,763 - 102,150,196 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936515571,139 - 600,132 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936515570,112 - 599,400 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMMR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1660,290,001 - 60,331,936 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11660,290,684 - 60,332,411 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21665,130,340 - 65,172,451 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HMMR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12365,732,343 - 65,765,511 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2365,732,553 - 65,765,511 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
ChlSab1.1 Ensembl2365,732,553 - 65,765,511 (+)NCBIChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236665744,011 - 37,808 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hmmr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473326,319,678 - 26,351,234 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473326,319,635 - 26,351,576 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Hmmr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1923,638,516 - 23,668,344 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Hmmr
253 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101577675460776754Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102293137391127454Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)101465354159653541Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101553301273695498Rat
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)102466212373695339Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)101993920764939207Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)101803578263035782Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
2298495Eae23Experimental allergic encephalomyelitis QTL 2316.93nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)101617552561175525Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101866841963668419Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)102011061465110614Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102183375861843633Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum immunoglobulin E level (CMO:0002101)102342212132490778Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101803578263035782Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023948641107713808Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101499153586964295Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014991535107713808Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014991535107556066Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)102011061465110614Rat

Markers in Region
RH94632  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,133,650 - 25,133,849 (+)MAPPERmRatBN7.2
Rnor_6.01025,861,372 - 25,861,570NCBIRnor6.0
Rnor_5.01025,712,239 - 25,712,437UniSTSRnor5.0
RGSC_v3.41025,733,257 - 25,733,455UniSTSRGSC3.4
Celera1024,693,268 - 24,693,466UniSTS
Cytogenetic Map10q12UniSTS
AU048333  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,136,453 - 25,136,660 (+)MAPPERmRatBN7.2
Rnor_6.01025,864,177 - 25,864,383NCBIRnor6.0
Rnor_5.01025,715,044 - 25,715,250UniSTSRnor5.0
RGSC_v3.41025,736,062 - 25,736,268UniSTSRGSC3.4
Celera1024,696,070 - 24,696,276UniSTS
Cytogenetic Map10q12UniSTS
UniSTS:236554  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21025,145,915 - 25,146,555 (+)MAPPERmRatBN7.2
Rnor_6.01025,873,663 - 25,874,302NCBIRnor6.0
Rnor_5.01025,723,835 - 25,724,474UniSTSRnor5.0
RGSC_v3.41025,746,224 - 25,746,863UniSTSRGSC3.4
Celera1024,705,539 - 24,706,178UniSTS
Cytogenetic Map10q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 90 59 6 354 190 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000085499   ⟹   ENSRNOP00000070444
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1025,635,915 - 25,665,390 (-)Ensembl
mRatBN7.2 Ensembl1025,134,540 - 25,161,001 (-)Ensembl
Rnor_6.0 Ensembl1025,861,490 - 25,890,639 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098903   ⟹   ENSRNOP00000085400
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1025,635,915 - 25,665,338 (-)Ensembl
mRatBN7.2 Ensembl1025,132,977 - 25,163,060 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114372   ⟹   ENSRNOP00000077422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1025,636,812 - 25,648,452 (-)Ensembl
mRatBN7.2 Ensembl1025,134,540 - 25,146,180 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000137152   ⟹   ENSRNOP00000104820
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1025,635,915 - 25,651,032 (-)Ensembl
RefSeq Acc Id: NM_012964   ⟹   NP_037096
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81025,636,041 - 25,665,215 (-)NCBI
mRatBN7.21025,133,769 - 25,162,943 (-)NCBI
Rnor_6.01025,861,490 - 25,890,639 (-)NCBI
Rnor_5.01025,712,357 - 25,740,811 (-)NCBI
RGSC_v3.41025,733,375 - 25,762,825 (-)RGD
Celera1024,693,386 - 24,722,348 (-)RGD
Sequence:
RefSeq Acc Id: XM_039085276   ⟹   XP_038941204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81025,635,249 - 25,665,389 (-)NCBI
mRatBN7.21025,132,933 - 25,163,029 (-)NCBI
RefSeq Acc Id: XM_039085278   ⟹   XP_038941206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81025,635,249 - 25,655,705 (-)NCBI
mRatBN7.21025,132,933 - 25,153,433 (-)NCBI
RefSeq Acc Id: NP_037096   ⟸   NM_012964
- UniProtKB: Q9WUF7 (UniProtKB/TrEMBL),   A0A8I6A3Z3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070444   ⟸   ENSRNOT00000085499
RefSeq Acc Id: XP_038941204   ⟸   XM_039085276
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038941206   ⟸   XM_039085278
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000077422   ⟸   ENSRNOT00000114372
Ensembl Acc Id: ENSRNOP00000085400   ⟸   ENSRNOT00000098903
Ensembl Acc Id: ENSRNOP00000104820   ⟸   ENSRNOT00000137152
Protein Domains
Hyaluronan-mediated motility receptor C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97779-F1-model_v2 AlphaFold P97779 1-498 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697106
Promoter ID:EPDNEW_R7631
Type:multiple initiation site
Name:Hmmr_1
Description:hyaluronan-mediated motility receptor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01025,890,667 - 25,890,727EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2805 AgrOrtholog
BioCyc Gene G2FUF-25492 BioCyc
Ensembl Genes ENSRNOG00000059894 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000085499 ENTREZGENE
  ENSRNOT00000137152 ENTREZGENE
InterPro HMMR_C UniProtKB/Swiss-Prot
  IHABP UniProtKB/Swiss-Prot
NCBI Gene 25460 ENTREZGENE
PANTHER HYALURONAN MEDIATED MOTILITY RECEPTOR UniProtKB/Swiss-Prot
  PTHR18956 UniProtKB/Swiss-Prot
Pfam HMMR_C UniProtKB/Swiss-Prot
  HMMR_N UniProtKB/Swiss-Prot
PhenoGen Hmmr PhenoGen
RatGTEx ENSRNOG00000059894 RatGTEx
TIGR TC228217
UniProt A0A0G2JXY1_RAT UniProtKB/TrEMBL
  A0A8I5XW44_RAT UniProtKB/TrEMBL
  A0A8I6A3Z3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LGT1_RAT UniProtKB/TrEMBL
  A6HDK6_RAT UniProtKB/TrEMBL
  A6HDK7_RAT UniProtKB/TrEMBL
  HMMR_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9WUF7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-20 Hmmr  hyaluronan-mediated motility receptor  Hmmr  hyaluronan mediated motility receptor (RHAMM)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Hmmr  hyaluronan mediated motility receptor (RHAMM)    hyaluronan mediated motility receptor  Name updated 1299863 APPROVED
2002-06-10 Hmmr  Hyaluronan mediated motility receptor (RHAMM)      Symbol and Name status set to approved 70586 APPROVED