Gene:	Fosl1 ( Rattus norvegicus ) fos-like antigen 1
Description:	protein, antigenically related to c-fos; involved in serum inducible cellular immediate-early transcriptional response
Synonyms:	Fra-1;  (details...)
ArrayIDs:	M19651_at; 6079701; 1390175_at; 1368489_at; 1375311_at; 6296092; 6734738; 6032279; A_42_P693821; 6508220; 5936642; 5722050; 6657406; 6385000; 5705849; 6253648; rc_AI044263_at; 6661828; rc_AI072112_at; 5760411; GE20079; GE21764; rc_AI072997_at;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: FOSL1     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Fosl1     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Fosl1 genome assembly 3.1 1 208244064 - 208252571     Rat Celera Assembly 1 200290637 - 200299144     RGSC genome assembly v3.4 1 208090612 - 208099118     Cytogenetic 1 q43 Mus musculus Fosl1 Mouse genome assembly build 36.1 19 5447698 - 5455938     Cytogenetic 19 19 A Homo sapiens FOSL1 human genome assembly 11 65416267 - 65424573     Human genome assembly build 36.2 11 65416268 - 65424573     Cytogenetic 11 q13   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology sequence-specific DNA binding,  protein dimerization activity,  transcription factor activity ...  (details...)
Biological Process	Gene Ontology response to gravity,  response to cytokine stimulus,  response to cAMP ...  (details...)
Cellular Component	Gene Ontology nucleus,  presynaptic membrane,  synaptosome ...  (details...)
Disease	Ontology Osteopetrosis,  Fibroadenoma,  Kidney Neoplasms ...  (details...)
Expression	Note Reference mRNA expressed in serum stimulated fibroblasts 632677
Regulation	Note Reference exhibits immediate-early transcriptional response to extracellular stimuli 632677
Homology	Note Reference amino acid homologous to the Fos gene 632677
External Links
Databases	DATABASE ID SOURCE SMART: BRLZ IPI PROSITE: BZIP IPI PROSITE: BZIP_BASIC IPI UNIPARC: UPI000012ABCD IPI KEGG Report: rno:25445 ENTREZGENE HomoloGene Group ID: 3967 ENTREZGENE Germonline: 2627 Pfam: bZIP_1 IPI KEGG Pathway: 04310 ENTREZGENE InterPro: TF_bZIP. IPI InterPro: Leuzip_Fos. IPI InterPro: bZIP_1. IPI Ensembl Protein: ENSRNOP00000027891 IPI IPI: IPI00187901 IPI Entrez Gene: Fosl1 ENTREZGENE IMAGE_CLONE: IMAGE:7459558 IMAGE-MGC_LOAD MGC_CLONE: MGC:114353 IMAGE-MGC_LOAD UniProt: FOSL1_RAT IPI Ensembl Genes: ENSRNOG00000020552 IPI RatMap: 41330 ENTREZGENE PRINTS: LEUZIPPRFOS. IPI
Sequences	Nucleotide: U24154 Get FASTA Search GEO Profiles Nucleotide: BC097342 Get FASTA Search GEO Profiles Nucleotide: CH473953 Get FASTA Search GEO Profiles Nucleotide: M19651 Get FASTA Search GEO Profiles Nucleotide: NM_012953 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: NP_037085 Get FASTA Protein: EDM12489 Get FASTA Protein: AAA82045 Get FASTA Protein: AAH97342 Get FASTA Protein: AAA41171 Get FASTA Protein: P10158 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 11306
References
Curated References	25 references in RGD related to Fosl1
Other References	20 other references at PubMed related to Fosl1
Database Information
RGD ID	2627
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 10-JUN-02: Fosl1 Fos-like antigen 1 APPROVED Symbol and Name status set to approved 70586