Dync1i1 (dynein cytoplasmic 1 intermediate chain 1) - Rat Genome Database

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Gene: Dync1i1 (dynein cytoplasmic 1 intermediate chain 1) Rattus norvegicus
Analyze
Symbol: Dync1i1
Name: dynein cytoplasmic 1 intermediate chain 1
RGD ID: 2512
Description: Enables microtubule binding activity and microtubule motor activity. Involved in vesicle transport along microtubule. Located in axon cytoplasm and perinuclear region of cytoplasm. Part of cytoplasmic dynein complex. Colocalizes with piccolo-bassoon transport vesicle. Orthologous to human DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1); PARTICIPATES IN mitochondria transport pathway; phagocytosis pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-amino-2-deoxy-D-glucopyranose; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytoplasmic dynein 1 intermediate chain 1; cytoplasmic dynein intermediate chain 1; DH IC-1; Dnci 1; Dnci1; Dncic1; dynein cytoplasmic 1 intermediate chain 1A; dynein cytoplasmic 1 intermediate chain 1B; dynein cytoplasmic 1 intermediate chain 1C; dynein cytoplasmic 1 intermediate chain 1D; dynein intermediate chain 1, cytosolic; dynein, cytoplasmic, intermediate chain 1; IC74-1A; IC74-1B; NOT NULL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8434,819,313 - 35,132,647 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl434,819,430 - 35,142,319 (+)EnsemblGRCr8
mRatBN7.2433,852,597 - 34,166,159 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx438,811,924 - 39,125,122 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0434,738,100 - 35,051,306 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0433,147,869 - 33,461,066 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0430,807,755 - 31,121,097 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl430,807,879 - 31,121,090 (+)Ensemblrn6Rnor6.0
Rnor_5.0430,714,935 - 31,028,010 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4430,496,410 - 30,809,622 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera429,377,971 - 29,690,505 (+)NCBICelera
RGSC_v3.1430,547,347 - 30,880,140 (+)NCBI
Cytogenetic Map4q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-methoxyethanol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP)
all-trans-retinoic acid  (EXP,ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucosamine  (EXP)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
CGP 52608  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
cyclosporin A  (ISO)
DDE  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (EXP)
diethyl phthalate  (EXP)
diisobutyl phthalate  (EXP)
diisononyl phthalate  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
hexadecanoic acid  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methimazole  (EXP)
methylseleninic acid  (ISO)
microcystin-LR  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nickel atom  (ISO)
nitroglycerin  (EXP)
oleic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
permethrin  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
thapsigargin  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. Dynein light chain regulates axonal trafficking and synaptic levels of Bassoon. Fejtova A, etal., J Cell Biol. 2009 Apr 20;185(2):341-55. doi: 10.1083/jcb.200807155.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. Ligon LA, etal., J Biol Chem. 2004 Apr 30;279(18):19201-8. Epub 2004 Feb 24.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function. Paschal BM, etal., J Cell Biol 1992 Sep;118(5):1133-43.
8. Identification and developmental regulation of a neuron-specific subunit of cytoplasmic dynein. Pfister KK, etal., Mol Biol Cell. 1996 Feb;7(2):331-43.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:11148215   PMID:15121898   PMID:15748847   PMID:16051887   PMID:16449194   PMID:19229290   PMID:20682791   PMID:21911489   PMID:22871113   PMID:23577064   PMID:23704327   PMID:24561039  
PMID:25540360  


Genomics

Comparative Map Data
Dync1i1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8434,819,313 - 35,132,647 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl434,819,430 - 35,142,319 (+)EnsemblGRCr8
mRatBN7.2433,852,597 - 34,166,159 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx438,811,924 - 39,125,122 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0434,738,100 - 35,051,306 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0433,147,869 - 33,461,066 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0430,807,755 - 31,121,097 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl430,807,879 - 31,121,090 (+)Ensemblrn6Rnor6.0
Rnor_5.0430,714,935 - 31,028,010 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4430,496,410 - 30,809,622 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera429,377,971 - 29,690,505 (+)NCBICelera
RGSC_v3.1430,547,347 - 30,880,140 (+)NCBI
Cytogenetic Map4q21NCBI
DYNC1I1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38795,772,554 - 96,110,322 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl795,772,459 - 96,110,322 (+)Ensemblhg38GRCh38
GRCh37795,401,866 - 95,739,634 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36795,239,838 - 95,565,660 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34795,046,552 - 95,372,375NCBI
Celera790,101,694 - 90,427,608 (+)NCBICelera
Cytogenetic Map7q21.3NCBI
HuRef790,008,652 - 90,347,456 (+)NCBIHuRef
CHM1_1795,331,673 - 95,669,665 (+)NCBICHM1_1
T2T-CHM13v2.0797,008,421 - 97,346,216 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2794,730,870 - 95,068,701 (+)NCBI
Dync1i1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3965,725,772 - 6,028,030 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl65,725,639 - 6,028,039 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3865,725,600 - 6,028,039 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl65,725,639 - 6,028,039 (+)Ensemblmm10GRCm38
MGSCv3765,675,639 - 5,978,039 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3665,675,808 - 5,978,039 (+)NCBIMGSCv36mm8
Celera65,874,647 - 6,178,900 (+)NCBICelera
Cytogenetic Map6A1NCBI
cM Map62.26NCBI
Dync1i1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543212,353,993 - 12,658,157 (+)Ensembl
ChiLan1.0NW_00495543212,383,582 - 12,657,491 (+)NCBIChiLan1.0ChiLan1.0
DYNC1I1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26113,609,266 - 113,935,357 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17161,873,907 - 162,199,996 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0787,724,604 - 88,050,624 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17101,311,839 - 101,637,149 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7101,344,053 - 101,648,607 (+)EnsemblpanPan2panpan1.1
DYNC1I1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11420,967,936 - 21,279,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1420,968,011 - 21,278,363 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1420,526,736 - 20,837,733 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01420,790,257 - 21,100,686 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1420,790,150 - 21,100,690 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11420,935,563 - 21,246,926 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01420,669,529 - 20,980,440 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01420,927,298 - 21,238,416 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dync1i1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511834,336,964 - 34,630,858 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365854,231,711 - 4,527,145 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365854,232,428 - 4,496,878 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC1I1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl975,414,755 - 75,760,519 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1975,414,663 - 75,760,527 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2983,031,974 - 83,173,009 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNC1I1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12152,950,983 - 53,271,113 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2152,950,874 - 53,271,130 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604251,081,941 - 51,402,088 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dync1i1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248132,490,706 - 2,825,412 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248132,490,745 - 2,826,230 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dync1i1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16132,611,294 - 132,731,099 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dync1i1
1543 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:286
Count of miRNA genes:175
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000013184
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)41308014658080146Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41564430960644309Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41103870656038706Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41103870656038706Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42228845340471598Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41103870656038706Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41890069763900697Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4145429897Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41103870656038706Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42228845363245191Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)41890069763900697Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41103870656038706Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4140471598Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4588999950889999Rat
7387227Uae40Urinary albumin excretion QTL 402.90.0052urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)41891315163913151Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42786220462997402Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42192515166925151Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41103870656038706Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43353881653719714Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42228845345429897Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41075870140490708Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 60 157 83 80 51 50 51 6 275 143 11 129 58 92 29 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001439344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001439346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006236026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC091353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC095999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC099174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU343215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000013184   ⟹   ENSRNOP00000013184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,819,441 - 35,132,647 (+)Ensembl
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
Rnor_6.0 Ensembl430,807,879 - 31,121,090 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100335   ⟹   ENSRNOP00000094274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,862,394 - 35,132,647 (+)Ensembl
mRatBN7.2 Ensembl433,895,878 - 34,166,149 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106012   ⟹   ENSRNOP00000080715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,819,450 - 35,132,653 (+)Ensembl
mRatBN7.2 Ensembl434,141,856 - 34,166,149 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109704   ⟹   ENSRNOP00000092857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,819,430 - 35,132,646 (+)Ensembl
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117171   ⟹   ENSRNOP00000085770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,819,430 - 35,132,646 (+)Ensembl
mRatBN7.2 Ensembl433,852,927 - 34,166,149 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161831   ⟹   ENSRNOP00000099557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,819,455 - 35,142,319 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000165413   ⟹   ENSRNOP00000112615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl434,819,492 - 35,115,854 (+)Ensembl
RefSeq Acc Id: NM_019234   ⟹   NP_062107
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8434,819,441 - 35,132,647 (+)NCBI
mRatBN7.2433,852,927 - 34,166,150 (+)NCBI
Rnor_6.0430,807,879 - 31,121,091 (+)NCBI
Rnor_5.0430,714,935 - 31,028,010 (+)NCBI
RGSC_v3.4430,496,410 - 30,809,622 (+)RGD
Celera429,377,971 - 29,690,505 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236026   ⟹   XP_006236088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8434,819,313 - 35,132,647 (+)NCBI
mRatBN7.2433,852,603 - 34,166,159 (+)NCBI
Rnor_6.0430,807,759 - 31,121,097 (+)NCBI
Rnor_5.0430,714,935 - 31,028,010 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592509   ⟹   XP_017447998
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8434,819,313 - 35,132,647 (+)NCBI
mRatBN7.2433,852,602 - 34,166,159 (+)NCBI
Rnor_6.0430,807,759 - 31,121,097 (+)NCBI
Sequence:
RefSeq Acc Id: NP_062107   ⟸   NM_019234
- UniProtKB: Q63100 (UniProtKB/Swiss-Prot),   A6IDT9 (UniProtKB/TrEMBL),   G3V792 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236088   ⟸   XM_006236026
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017447998   ⟸   XM_017592509
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000013184   ⟸   ENSRNOT00000013184
Ensembl Acc Id: ENSRNOP00000085770   ⟸   ENSRNOT00000117171
Ensembl Acc Id: ENSRNOP00000092857   ⟸   ENSRNOT00000109704
Ensembl Acc Id: ENSRNOP00000094274   ⟸   ENSRNOT00000100335
Ensembl Acc Id: ENSRNOP00000080715   ⟸   ENSRNOT00000106012
Ensembl Acc Id: ENSRNOP00000112615   ⟸   ENSRNOT00000165413
Ensembl Acc Id: ENSRNOP00000099557   ⟸   ENSRNOT00000161831

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63100-F1-model_v2 AlphaFold Q63100 1-643 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692862
Promoter ID:EPDNEW_R3386
Type:initiation region
Name:Dync1i1_1
Description:dynein cytoplasmic 1 intermediate chain 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0430,807,912 - 30,807,972EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2512 AgrOrtholog
BioCyc Gene G2FUF-45702 BioCyc
Ensembl Genes ENSRNOG00000009700 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013184 ENTREZGENE
  ENSRNOT00000106012 ENTREZGENE
  ENSRNOT00000117171 ENTREZGENE
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
InterPro DYNC1I1/DYNC1I2 UniProtKB/Swiss-Prot
  Dynein_IC UniProtKB/Swiss-Prot
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:29564 UniProtKB/Swiss-Prot
NCBI Gene Dync1i1 ENTREZGENE
PANTHER CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN 1 UniProtKB/Swiss-Prot
  DYNEIN INTERMEDIATE CHAIN UniProtKB/Swiss-Prot
Pfam Dynein_IC2 UniProtKB/Swiss-Prot
  WD40 UniProtKB/Swiss-Prot
PhenoGen Dync1i1 PhenoGen
PROSITE WD_REPEATS_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009700 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
TIGR TC206306
UniProt A0A173DW29 ENTREZGENE, UniProtKB/TrEMBL
  A0A173DW30 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A2D5_RAT UniProtKB/TrEMBL
  A0A8I6AHE2_RAT UniProtKB/TrEMBL
  A0A8I6AKL2_RAT UniProtKB/TrEMBL
  A0A8I6G4X7_RAT UniProtKB/TrEMBL
  A0ABK0LFC5_RAT UniProtKB/TrEMBL
  A0ABK0M0Z7_RAT UniProtKB/TrEMBL
  A6IDT9 ENTREZGENE, UniProtKB/TrEMBL
  A6IDU1 ENTREZGENE, UniProtKB/TrEMBL
  DC1I1_RAT UniProtKB/Swiss-Prot
  G3V792 ENTREZGENE, UniProtKB/TrEMBL
  Q63100 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Dync1i1  dynein cytoplasmic 1 intermediate chain 1  Dncic1  dynein, cytoplasmic, intermediate chain 1  Symbol and Name updated 1299863 APPROVED
2002-11-06 Dncic1  dynein, cytoplasmic, intermediate chain 1  Dnci1    Symbol and Name updated 625702 APPROVED
2002-06-10 Dnci1  dynein, cytoplasmic, intermediate chain 1      Name updated 70584 APPROVED
2001-12-06 Dnci 1  dynein, cytoplasmic, intermediate chain 1      Symbol updated to reflect Human and Mouse nomenclature 69665 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds alpha tubulin 69826
gene_process may mediate the interaction of cytoplasmic dynein with membranous organelles and kinetochores 69826
gene_process may be involved in subcellular targeting 69826