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Gene: Ceacam3 (CEA cell adhesion molecule 3) Rattus norvegicus

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Symbol:

Ceacam3

Name:

CEA cell adhesion molecule 3

RGD ID:

2333

Description:

Predicted to be involved in T cell activation and immune response. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM21 (CEA cell adhesion molecule 21).

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

carcinoembryonic antigen CGM1; Carcinoembryonic antigen gene family (CGM1); carcinoembryonic antigen gene family 4; Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein); carcinoembryonic antigen-related cell adhesion molecule 3; Cea; Ceacam5; Cear; cell adhesion molecule CEACAM3; Cgm1; Cgm4; CGM4AA; MGC114355; RATCEAA; RATCGM4AA

RGD Orthologs

Mouse

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Ceacam3 (CEA cell adhesion molecule 3)	RGD	RGD
Other homologs ²
Homo sapiens (human):	CEACAM21 (CEA cell adhesion molecule 21)	HGNC	Panther, Treefam
Alliance orthologs ³
Homo sapiens (human):	CEACAM7 (CEA cell adhesion molecule 7)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Homo sapiens (human):	CEACAM21 (CEA cell adhesion molecule 21)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	CEACAM21 (CEA cell adhesion molecule 21)	Alliance	DIOPT (HGNC\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Ceacam3 (CEA cell adhesion molecule 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-27e22.1	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:ch73-213k20.5	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:rp71-36a1.3	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:ch211-239m17.1	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:ch211-239m17.1	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:ch73-27e22.4	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:ch211-274k16.2	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	zgc:171497	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	zgc:172133	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:dkey-182g1.3	Alliance	DIOPT (Hieranoid\|InParanoid)
Danio rerio (zebrafish):	si:dkey-19a16.12	Alliance	DIOPT (Hieranoid\|InParanoid)
Xenopus tropicalis (tropical clawed frog):	ceacam19ly	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ceacam19lm	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100493247	Alliance	DIOPT (Ensembl Compara\|InParanoid\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,991,944 - 87,004,518 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	86,991,984 - 87,004,701 (+)	Ensembl				GRCr8
mRatBN7.2	1	77,863,907 - 77,876,441 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	77,863,907 - 77,876,624 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	83,242,986 - 83,255,553 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	91,807,056 - 91,819,623 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,998,111 - 85,010,678 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,122,593 - 79,135,127 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,122,608 - 79,135,310 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	80,368,019 - 80,380,553 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	77,529,236 - 77,541,770 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	72,348,561 - 72,361,095 (+)	NCBI		Celera
RGSC_v3.1	1	77,607,361 - 77,620,064 (+)	NCBI
RH 3.4 Map	1	793.5	RGD
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

immune response (IBA)

T cell activation (IBA)

Cellular Component

external side of plasma membrane (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Identification of a carcinoembryonic antigen gene family in the rat. Analysis of the N-terminal domains reveals immunoglobulin-like, hypervariable regions.	Kodelja V, etal., J Biol Chem 1989 Apr 25;264(12):6906-12.
3.	High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence.	Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	cDNA and gene analyses imply a novel structure for a rat carcinoembryonic antigen-related protein.	Rebstock S, etal., J Biol Chem 1990 May 15;265(14):7872-9.
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation
9.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data

Additional References at PubMed

PMID:8136522	PMID:12477932

Genomics

Comparative Map Data

Ceacam3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	86,991,944 - 87,004,518 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	86,991,984 - 87,004,701 (+)	Ensembl				GRCr8
mRatBN7.2	1	77,863,907 - 77,876,441 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	77,863,907 - 77,876,624 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	83,242,986 - 83,255,553 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	91,807,056 - 91,819,623 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	84,998,111 - 85,010,678 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	79,122,593 - 79,135,127 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	79,122,608 - 79,135,310 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	80,368,019 - 80,380,553 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	77,529,236 - 77,541,770 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	72,348,561 - 72,361,095 (+)	NCBI		Celera
RGSC_v3.1	1	77,607,361 - 77,620,064 (+)	NCBI
RH 3.4 Map	1	793.5	RGD
Cytogenetic Map	1	q21	NCBI

Ceacam3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	16,884,122 - 16,898,891 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	16,884,207 - 16,898,178 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	17,150,197 - 17,164,966 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	17,150,282 - 17,164,253 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	17,735,749 - 17,748,580 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	16,308,922 - 16,321,753 (+)	NCBI		MGSCv36	mm8
MGSCv36	7	12,291,993 - 12,304,909 (+)	NCBI		MGSCv36	mm8
Celera	7	14,357,312 - 14,370,146 (+)	NCBI		Celera
Cytogenetic Map	7	A2	NCBI
cM Map	7	9.15	NCBI

Variants

Variants in Ceacam3
48 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	511
Count of miRNA genes:	257
Interacting mature miRNAs:	308
Transcripts:	ENSRNOT00000023663
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	43457837	87558729	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	51940904	101229020	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	39728272	132889942	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	46302615	91302615	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	43457837	87558729	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	46302615	91302615	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	42122968	87122968	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	83019780	128019780	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	66404680	111404680	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	46302615	91302615	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	81269860	99645535	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	43457837	87558729	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	46302615	91302615	Rat
1302788	Scl19	Serum cholesterol QTL 19	4.6	0.001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	66400974	132889942	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	84107164	115183752	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	30708375	87558729	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	65405637	96805205	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	51909206	91302615	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	86622262	131622262	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	58769992	103769992	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	46302615	91302615	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	66077886	111077886	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	46302615	91302615	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	43509952	88509952	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	52891222	109116986	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	86993904	131993904	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	42122968	87122968	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	46302615	91302615	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	43509952	88509952	Rat

Markers in Region

D1Arb32

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	86,992,573 - 86,992,866 (+)	Marker Load Pipeline
mRatBN7.2	1	77,864,496 - 77,864,789 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,123,183 - 79,123,475	NCBI	Rnor6.0
Rnor_5.0	1	80,368,609 - 80,368,901	UniSTS	Rnor5.0
RGSC_v3.4	1	77,529,825 - 77,530,118	RGD	RGSC3.4
RGSC_v3.4	1	77,529,826 - 77,530,118	UniSTS	RGSC3.4
Celera	1	72,349,151 - 72,349,443	UniSTS
RGSC_v3.1	1	77,607,936 - 77,608,229	RGD
SHRSP x BN Map	1	40.2499	RGD
SHRSP x BN Map	1	40.2499	UniSTS
FHH x ACI Map	1	38.9799	RGD
Cytogenetic Map	1	q21	UniSTS

D1Arb33

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	77,876,254 - 77,876,500 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,134,941 - 79,135,186	NCBI	Rnor6.0
Rnor_5.0	1	80,380,367 - 80,380,612	UniSTS	Rnor5.0
RGSC_v3.4	1	77,541,583 - 77,541,829	RGD	RGSC3.4
RGSC_v3.4	1	77,541,584 - 77,541,829	UniSTS	RGSC3.4
Celera	1	72,360,909 - 72,361,154	UniSTS
RGSC_v3.1	1	77,619,694 - 77,619,940	RGD
RH 3.4 Map	1	795.6	RGD
RH 3.4 Map	1	795.6	UniSTS
SHRSP x BN Map	1	40.2499	RGD
SHRSP x BN Map	1	40.2499	UniSTS
FHH x ACI Map	1	39.05	RGD
Cytogenetic Map	1	q21	UniSTS

D1Mgh5

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	87,558,587 - 87,558,729 (+)	Marker Load Pipeline
mRatBN7.2	1	78,430,536 - 78,430,678 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,689,548 - 79,689,689	NCBI	Rnor6.0
Rnor_5.0	1	80,946,174 - 80,946,315	UniSTS	Rnor5.0
RGSC_v3.4	1	78,134,304 - 78,134,446	RGD	RGSC3.4
RGSC_v3.4	1	78,134,305 - 78,134,446	UniSTS	RGSC3.4
Celera	1	72,898,184 - 72,898,325	UniSTS
RGSC_v3.1	1	78,212,415 - 78,212,557	RGD
RH 3.4 Map	1	791.5	RGD
RH 3.4 Map	1	791.5	UniSTS
RH 2.0 Map	1	501.0	RGD
SHRSP x BN Map	1	40.2499	RGD
FHH x ACI Map	1	40.1	RGD
Cytogenetic Map	1	q21	UniSTS

D1Wox15

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,908,663 - 86,908,835 (+)	Marker Load Pipeline
RH 3.4 Map	1	795.5	UniSTS
RH 3.4 Map	1	795.5	RGD
RH 2.0 Map	1	494.1	RGD
Cytogenetic Map	1	q21	UniSTS

D1Arb52

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	77,864,810 - 77,864,930 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,123,497 - 79,123,616	NCBI	Rnor6.0
Rnor_5.0	1	80,368,923 - 80,369,042	UniSTS	Rnor5.0
RGSC_v3.4	1	77,530,139 - 77,530,259	RGD	RGSC3.4
RGSC_v3.4	1	77,530,140 - 77,530,259	UniSTS	RGSC3.4
Celera	1	72,349,465 - 72,349,584	UniSTS
RGSC_v3.1	1	77,608,250 - 77,608,370	RGD
Cytogenetic Map	1	q21	UniSTS

RH94692

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	87,004,182 - 87,004,331 (+)	Marker Load Pipeline
mRatBN7.2	1	77,876,105 - 77,876,254 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,134,792 - 79,134,940	NCBI	Rnor6.0
Rnor_5.0	1	80,380,218 - 80,380,366	UniSTS	Rnor5.0
RGSC_v3.4	1	77,541,435 - 77,541,583	UniSTS	RGSC3.4
Celera	1	72,360,760 - 72,360,908	UniSTS
RH 3.4 Map	1	793.5	UniSTS
Cytogenetic Map	1	q21	UniSTS

BI274949

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	77,876,797 - 77,876,941 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	79,135,484 - 79,135,627	NCBI	Rnor6.0
Rnor_5.0	1	80,380,910 - 80,381,053	UniSTS	Rnor5.0
RGSC_v3.4	1	77,542,127 - 77,542,270	UniSTS	RGSC3.4
Celera	1	72,361,452 - 72,361,595	UniSTS
RH 3.4 Map	1	793.6	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	1	6	39	22	20	11	5	11	5	41	19	30	4	32	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC125877	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH003118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC098921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L00686	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M32474	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M60023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000023663 ⟹ ENSRNOP00000023663

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,991,999 - 87,004,701 (+)	Ensembl
mRatBN7.2 Ensembl	1	77,863,922 - 77,876,624 (+)	Ensembl
Rnor_6.0 Ensembl	1	79,122,608 - 79,135,310 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000088393 ⟹ ENSRNOP00000069736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	86,991,984 - 87,003,673 (+)	Ensembl
mRatBN7.2 Ensembl	1	77,863,907 - 77,875,596 (+)	Ensembl

RefSeq Acc Id:

NM_012702 ⟹ NP_036834

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,991,984 - 87,004,518 (+)	NCBI
mRatBN7.2	1	77,863,907 - 77,876,441 (+)	NCBI
Rnor_6.0	1	79,122,593 - 79,135,127 (+)	NCBI
Rnor_5.0	1	80,368,019 - 80,380,553 (+)	NCBI
RGSC_v3.4	1	77,529,236 - 77,541,770 (+)	RGD
Celera	1	72,348,561 - 72,361,095 (+)	RGD

Sequence:

show sequence

CAATCCACAGATTCTGGGAAGTGCTCCTCCTTGAGAGGACACCTAGCTCAAGAGGAGGAAAGAC
AATAACAGTTAGGTGCCTTGCTGGAACGAAAGCTCCTCTCCTAAGAGTGAGGCCATTCTAGTGA
GAAGACAGATGGAGCTGTCCTCTGTGCTTCCCTGCAAGAGGTGTACTCCCTGGCGGGGGCTCCT
GCTCACAGCCTCCCTCTTAACCTGCTGGCTCCTGCCCACCACTGCCCAAGTCTCCATTGAATCC
TTACCACCCCAGGTGGTTGAAGGAGAAAATGTTCTTCTACGTGTTGACAATTTGCCAGAGAATC
TCATAGCCTTTGTCTGGTACAAAGGGCTGACAAACATGAGCCTCGGAGTTGCACTGTATTCACT
AACCTATAACGTAACTGTGACGGGACCTGTGCACAGTGGTAGAGAGACATTGTACAGCAATGGG
TCCCTGTGGATCCAAAATGTCACCCAGAAGGACACAGGATTCTACACCCTACGAACCATAAGTA
ATCATGGAGAAATTGTATCAAATACATCCCTGCACCTTCATGTGTACTTCTCCACTTTGACCTG
TGGACGCGCTGCCACCTCTGCTCAGCTCAGTATTGAATCAGTGCCGACCAGCATCTCTAAAGGA
GAAAGCGCTCTTCTCCTTGCTCACAATCTCCCAGAGAATCTCCGAGCCATTTTCTGGTATAAAG
GGGCGATTGTGTTCAAGGACCTTGAGGTTGCTCGATATGTAATAGGCACAAATTCAAGTGTGCC
GGGGCCTGCCCACAACGGCAGAGAGACAATGTACAGCAATGGATCCCTCCTGCTTCAGAATGTC
ACTCGGAACGATGCTGGATTCTACACCTTAAAAACTCTGAGTACAGATCTGAAAACTGAAATAG
CCTATGTGCAACTCCAGGTGGACACCTGTTTTATGAGCTATGCTGGCCCTCCCACTTCTGCCCA
GCTCACTGTCGAATCAGCGCCTACCAGCGTTGCTGAAGGAGCAAGCGTTCTTCTCCTTGCTCAT
AATCTCCCTGAGAATCTCCGAGCCATTTTCTGGTATAAAGGGGCGATTTTGTTCAAGGACCTTG
AGGTTGCTCGATATGTAATAGGCACAAATTCAAGTGTGCCGGGGCCTGCCCACAGCGGCAGAGA
GACAATGCACAGCAATGGATCCCTCCTGCTTCAGAATGTCACTCGGAACGATGCTGGATTCTAC
ACCTTAAGAACTCTGAGTACAGATCTGAAAGCTAAAGTAGTACATGTGCAACTCCAGGTGAACA
CCTCCTCGTGCTGTGACCCTCTCACTCCTGCCCCACTCACGATAGACCCAGTGCCACGGCATGC
GGCTAAAGGGGAAAGTGTTCTTCTTCAAGTTCGCAATCTGCCAGAGGATCTGCGAATGTTTATC
TGGTTCAAATCTGTGTATACCTCCCAGATCTTTAAAATAGCAGAGTACAGCAGAGCCATTAATT
ACGTCTTCAGGGGCCCTGCACACAGCGGAAGAGAGACAGTGTACACGAATGGATCCCTGCTGCT
CCAGGATGCCACTGAGAAAGACACAGGCTTGTACACACTACAAATAATATACAGAAATTTCAAA
ATTGAAACAGCACACGTTCAAGTCAGCGTGCACACCTGTGTTCACCCTTCTACCACTGGCCAGC
TTGTAATCGAATCGGTGCCACCCAATGTTGTTGAAGGGGGAGACGTTCTCCTACTTGTTCATAA
TATGCCAGAGAACCTTCAATCCTTTTCCTGGTACAAAGGCGTAGCCATTGTCAACAGACATGAA
ATCTCTCGGAACATAATAGCCAGTAATAGAAGCACATTGGGGCCTGCTCACAGTGGCAGAGAGA
CAATATATTCTAATGGCTCTCTTCTGCTCCACAATGCCACCGAGGAGGACAATGGATTATACAC
CTTATGGACTGTAAACAGACATTCTGAAACTCAAGGGATACACGTGCACATCCACATATACAAG
CCTGTGGCACAGCCCTTTATCCGAGTCACTGAATCCTCAGTCAGAGTGAAGAGCTCTGTGGTCC
TCACCTGCCTCTCAGCTGACACTGGAACCTCCATCCAGTGGCTCTTCAACAACCAGAATCTGCG
GCTCACACAGAGGATGTTGCTGTCCCAGACTAAGTGCCAACTCAGCATAGATCCCGTCAGGAGG
GAGGATGCTGGAGAGTATAGGTGTGAGGTCTCCAACCCGGTCAGTTCGAAGACGAGCCTCCCAG
TCAGCCTGGATGTGATCATTGAGTGACCCCCCACCTTCTCTCATCCTACAGCAGAGTGGGGGAC
ATTTCTTTATCAATGGGTACAAAATGGAGCAAAATTATGTGGTGAAAATTGTCAGTTGCTACTC
AGGTACAGTCAGCATGTTGAGTCATGTCTGTATCCCTAGGATAAACATGTACAAGGACAAGCCA
GAACATAGAGACTCAGTTTCCAAAAAAAAGAAAACATCAATACAGTAAACAGTATTGTAGTGGT
GTTAAGAGTTAGGTTGTGGATCAAATACATAGCCAATCCTCAGAATCCATGGGAACTAATTTCA
GGAGCCACCAATATTCTGTATGCTCCAAGTCCCCTGTTAGCATGGTGCAGTGACTTCATAGAGA
TAAATGCATCTTTTGCATGCTTAAGTATATTCTGTGTATAACTAATTCACATAGTACCATTACT
GTCTGGGCACCAGTTATCCATGTGAAGAAAGGACAAGCAACAGGAGAAGGGACTGCCCTTTCCC
AGTGGACATAACTTGTGTCTAAATAGTTTTGATCCACAGTTGGGTGTAACATTCATAGCAGAGA
CCCAACTCTGGACTCTGTATATCCTGACAGTGGCATTCATAAGATTCTTATTCCTGTTTTTTCT
TCCTTCCTTCCTTCCTTCCTTCCTTCTGAAGGGCATATATGGGATTTCCCATTTTGAGTATTTT
GAAGTGGGCAATTAACATGAAACACACTCATATTGTCATGTGACCAATAAATGTTGTCCATTCT
CAAAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039101138 ⟹ XP_038957066

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,991,944 - 87,003,769 (+)	NCBI
mRatBN7.2	1	77,864,031 - 77,875,692 (+)	NCBI

RefSeq Acc Id:

XM_063281070 ⟹ XP_063137140

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	86,991,944 - 87,003,769 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_036834	(Get FASTA)	NCBI Sequence Viewer
	XP_038957066	(Get FASTA)	NCBI Sequence Viewer
	XP_063137140	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA40908	(Get FASTA)	NCBI Sequence Viewer
	AAA66037	(Get FASTA)	NCBI Sequence Viewer
	AAA68202	(Get FASTA)	NCBI Sequence Viewer
	AAH98921	(Get FASTA)	NCBI Sequence Viewer
	EDM08274	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000023663
	ENSRNOP00000069736
GenBank Protein	Q63111	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_036834 ⟸ NM_012702
- Peptide Label:	precursor
- UniProtKB:	Q63111 (UniProtKB/Swiss-Prot), Q63101 (UniProtKB/Swiss-Prot), Q4KLZ7 (UniProtKB/TrEMBL), A6J8G0 (UniProtKB/TrEMBL), F7FFP7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELSSVLPCKRCTPWRGLLLTASLLTCWLLPTTAQVSIESLPPQVVEGENVLLRVDNLPENLIA FVWYKGLTNMSLGVALYSLTYNVTVTGPVHSGRETLYSNGSLWIQNVTQKDTGFYTLRTISNHG EIVSNTSLHLHVYFSTLTCGRAATSAQLSIESVPTSISKGESALLLAHNLPENLRAIFWYKGAI VFKDLEVARYVIGTNSSVPGPAHNGRETMYSNGSLLLQNVTRNDAGFYTLKTLSTDLKTEIAYV QLQVDTCFMSYAGPPTSAQLTVESAPTSVAEGASVLLLAHNLPENLRAIFWYKGAILFKDLEVA RYVIGTNSSVPGPAHSGRETMHSNGSLLLQNVTRNDAGFYTLRTLSTDLKAKVVHVQLQVNTSS CCDPLTPAPLTIDPVPRHAAKGESVLLQVRNLPEDLRMFIWFKSVYTSQIFKIAEYSRAINYVF RGPAHSGRETVYTNGSLLLQDATEKDTGLYTLQIIYRNFKIETAHVQVSVHTCVHPSTTGQLVI ESVPPNVVEGGDVLLLVHNMPENLQSFSWYKGVAIVNRHEISRNIIASNRSTLGPAHSGRETIY SNGSLLLHNATEEDNGLYTLWTVNRHSETQGIHVHIHIYKPVAQPFIRVTESSVRVKSSVVLTC LSADTGTSIQWLFNNQNLRLTQRMLLSQTKCQLSIDPVRREDAGEYRCEVSNPVSSKTSLPVSL DVIIE hide sequence

Ensembl Acc Id:

ENSRNOP00000023663 ⟸ ENSRNOT00000023663

RefSeq Acc Id:	XP_038957066 ⟸ XM_039101138
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW44 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000069736 ⟸ ENSRNOT00000088393

RefSeq Acc Id:	XP_063137140 ⟸ XM_063281070
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2JW44 (UniProtKB/TrEMBL)

Protein Domains

Ig-like Ig-like C2-type Ig-like V-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q63111-F1-model_v2	AlphaFold	Q63111	1-709	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2333	AgrOrtholog
BioCyc Gene	G2FUF-60574	BioCyc
Ensembl Genes	ENSRNOG00000027607	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000023663	ENTREZGENE
	ENSRNOT00000088393	ENTREZGENE
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7441743	IMAGE-MGC_LOAD
InterPro	CEA_cell_adhesion	UniProtKB/Swiss-Prot
	Ig-like_dom	UniProtKB/Swiss-Prot
	Ig-like_dom_sf	UniProtKB/Swiss-Prot
	Ig-like_fold	UniProtKB/Swiss-Prot
	Ig_sub	UniProtKB/Swiss-Prot
	Ig_sub2	UniProtKB/Swiss-Prot
	Ig_V-set	UniProtKB/Swiss-Prot
	Immunoglobulin	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:114355	IMAGE-MGC_LOAD
NCBI Gene	24926	ENTREZGENE
PANTHER	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1	UniProtKB/Swiss-Prot
	CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19	UniProtKB/Swiss-Prot
Pfam	PF00047	UniProtKB/Swiss-Prot
	V-set	UniProtKB/Swiss-Prot
PhenoGen	Ceacam3	PhenoGen
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000027607	RatGTEx
SMART	IGc2	UniProtKB/Swiss-Prot
	SM00409	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot
TIGR	TC232097
UniProt	A0A0G2JW44	ENTREZGENE, UniProtKB/TrEMBL
	A6J8G0	ENTREZGENE, UniProtKB/TrEMBL
	CEAM3_RAT	UniProtKB/Swiss-Prot
	F7FFP7	ENTREZGENE, UniProtKB/TrEMBL
	Q4KLZ7	ENTREZGENE
	Q63101	ENTREZGENE
	Q63111	ENTREZGENE
UniProt Secondary	Q63101	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-09-09	Ceacam3	CEA cell adhesion molecule 3	Ceacam3	carcinoembryonic antigen-related cell adhesion molecule 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-04-27	Ceacam3	carcinoembryonic antigen-related cell adhesion molecule 3	Cgm4	carcinoembryonic antigen gene family 4	Data merged from RGD:2335	737654	APPROVED
2002-11-06	Ceacam3	carcinoembryonic antigen-related cell adhesion molecule 3	Cgm1	Carcinoembryonic antigen gene family (CGM1)	Symbol and Name updated	625702	APPROVED
2002-11-06	Cgm4	carcinoembryonic antigen gene family 4		Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein)	Name updated	625702	APPROVED
2002-06-10	Cgm4	Carcinoembryonic antigen gene family member 4 / (carcinoembryonic antigene-related protein)			Symbol and Name status set to approved	70586	APPROVED
2002-06-10	Cgm1	Carcinoembryonic antigen gene family (CGM1)			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains five IgV-like domains and one IgC-like domain	1298756
gene_expression	expressed in placenta	1298756
gene_function	may function as a receptor	632404
gene_product	belongs to immunoglobulin supergene family	632404

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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