Zfp658l1 (zinc finger protein 658-like 1) - Rat Genome Database

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Gene: Zfp658l1 (zinc finger protein 658-like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Zfp658l1
Name: zinc finger protein 658-like 1
RGD ID: 2324613
Description: Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF788P (zinc finger family member 788, pseudogene).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: inhibitor of four 1; LOC100363068; LOC100366030; LOC102554485; rCG37858-like; zinc finger protein 14-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8145,194,182 - 5,242,944 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl145,234,125 - 5,243,077 (-)EnsemblGRCr8
mRatBN7.2144,889,486 - 4,938,248 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl144,869,196 - 4,938,277 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx144,833,560 - 4,882,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0146,133,754 - 6,183,085 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0144,835,576 - 4,884,929 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0146,101,453 - 6,148,925 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl146,101,457 - 6,148,925 (-)Ensemblrn6Rnor6.0
Rnor_6.0 Ensembl146,192,692 - 6,201,002 (-)Ensemblrn6Rnor6.0
Rnor_5.0146,082,446 - 6,129,918 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4145,997,249 - 6,046,037 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera145,029,838 - 5,078,886 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16904636  


Genomics

Variants

.
Variants in Zfp658l1
722 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:108
Count of miRNA genes:91
Interacting mature miRNAs:93
Transcripts:ENSRNOT00000049165, ENSRNOT00000075091
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
724541Niddm53Non-insulin dependent diabetes mellitus QTL 530.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1439578789393298Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14111334906Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat

Markers in Region
RH129250  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2144,891,932 - 4,892,124 (+)MAPPERmRatBN7.2
Rnor_6.0146,103,900 - 6,104,091NCBIRnor6.0
Rnor_5.0146,084,893 - 6,085,084UniSTSRnor5.0
RGSC_v3.4145,999,692 - 5,999,883UniSTSRGSC3.4
Celera145,032,285 - 5,032,476UniSTS
RH 3.4 Map1487.5UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 1 61 177 92 84 60 56 60 11 301 148 11 153 80 99 24 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000049165   ⟹   ENSRNOP00000039029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl146,192,692 - 6,201,002 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075091   ⟹   ENSRNOP00000065425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl144,869,196 - 4,938,277 (-)Ensembl
Rnor_6.0 Ensembl146,140,190 - 6,148,830 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092683   ⟹   ENSRNOP00000075802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl145,234,125 - 5,243,077 (-)Ensembl
mRatBN7.2 Ensembl144,889,375 - 4,938,277 (-)Ensembl
Rnor_6.0 Ensembl146,101,457 - 6,148,925 (-)Ensembl
RefSeq Acc Id: NM_001177909   ⟹   NP_001171380
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8145,194,182 - 5,242,944 (-)NCBI
mRatBN7.2144,889,486 - 4,938,248 (-)NCBI
Rnor_6.0146,101,453 - 6,148,925 (-)NCBI
Rnor_5.0146,082,446 - 6,129,918 (-)NCBI
Celera145,029,838 - 5,078,886 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001171380 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAO92640 (Get FASTA)   NCBI Sequence Viewer  
  EDL99479 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075802
  ENSRNOP00000075802.2
RefSeq Acc Id: NP_001171380   ⟸   NM_001177909
- UniProtKB: F1LX67 (UniProtKB/TrEMBL),   A6K5Q9 (UniProtKB/TrEMBL),   Q80V39 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075802   ⟸   ENSRNOT00000092683
Ensembl Acc Id: ENSRNOP00000065425   ⟸   ENSRNOT00000075091
Ensembl Acc Id: ENSRNOP00000039029   ⟸   ENSRNOT00000049165
Protein Domains
KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LX67-F1-model_v2 AlphaFold F1LX67 1-74 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2324613 AgrOrtholog
BioCyc Gene G2FUF-16524 BioCyc
Ensembl Genes ENSRNOG00000047293 Ensembl
  ENSRNOG00000049446 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000092683 ENTREZGENE
  ENSRNOT00000092683.3 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
InterPro KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2-type UniProtKB/TrEMBL
KEGG Report rno:100366030 UniProtKB/TrEMBL
NCBI Gene 100366030 ENTREZGENE
PANTHER RIKEN CDNA 6720489N17 GENE-RELATED UniProtKB/TrEMBL
  ZNF44 PROTEIN UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
PhenoGen Zfp658l1 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047293 RatGTEx
  ENSRNOG00000049446 RatGTEx
SMART KRAB UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
UniProt A6K5Q9 ENTREZGENE, UniProtKB/TrEMBL
  F1LX67 ENTREZGENE, UniProtKB/TrEMBL
  Q80V39 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Zfp658l1  zinc finger protein 658-like 1  LOC100366030  rCG37858-like  Symbol and Name Changed 1299863 APPROVED
2021-03-09 LOC100366030  rCG37858-like  LOC102554485  zinc finger protein 14-like  Data merged from RGD:7721775 737654 PROVISIONAL
2015-07-29 LOC100366030  rCG37858-like  LOC100363068  rCG37858-like  Data merged from RGD:2324821 737654 PROVISIONAL
2013-12-18 LOC102554485  zinc finger protein 14-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-12 LOC100363068  rCG37858-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-06 LOC100366030  rCG37858-like      Symbol and Name status set to provisional 70820 PROVISIONAL