Anapc16 (anaphase promoting complex subunit 16) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Anapc16 (anaphase promoting complex subunit 16) Rattus norvegicus
Analyze
Symbol: Anapc16
Name: anaphase promoting complex subunit 16
RGD ID: 2321124
Description: Predicted to be involved in protein ubiquitination. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytosol and kinetochore. Orthologous to human ANAPC16 (anaphase promoting complex subunit 16); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: anaphase-promoting complex subunit 16; LOC100360936; rCG22080-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82028,470,282 - 28,484,601 (-)NCBIGRCr8
mRatBN7.22027,927,334 - 27,941,644 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2027,927,334 - 27,941,984 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2028,938,989 - 28,953,312 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02028,325,249 - 28,339,573 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02029,068,021 - 29,082,282 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02029,544,626 - 29,558,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,544,629 - 29,558,321 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,349,974 - 31,364,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,287,617 - 27,301,901 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2029,368,635 - 29,382,937 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
protein ubiquitination  (IBA,IEA,ISO)

Cellular Component
anaphase-promoting complex  (IBA,ISO)
cytosol  (IBA,ISO)
kinetochore  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:20360068   PMID:20813266  


Genomics

Comparative Map Data
Anapc16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82028,470,282 - 28,484,601 (-)NCBIGRCr8
mRatBN7.22027,927,334 - 27,941,644 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2027,927,334 - 27,941,984 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2028,938,989 - 28,953,312 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02028,325,249 - 28,339,573 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02029,068,021 - 29,082,282 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02029,544,626 - 29,558,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2029,544,629 - 29,558,321 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02031,349,974 - 31,364,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42027,287,617 - 27,301,901 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2029,368,635 - 29,382,937 (-)NCBICelera
Cytogenetic Map20q11NCBI
ANAPC16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381072,216,012 - 72,235,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1072,216,000 - 72,235,860 (+)EnsemblGRCh38hg38GRCh38
GRCh371073,975,770 - 73,995,618 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361073,645,812 - 73,665,624 (+)NCBINCBI36Build 36hg18NCBI36
Build 341073,645,811 - 73,665,622NCBI
Celera1067,259,517 - 67,279,309 (+)NCBICelera
Cytogenetic Map10q22.1NCBI
HuRef1067,970,007 - 67,989,866 (+)NCBIHuRef
CHM1_11074,257,500 - 74,277,376 (+)NCBICHM1_1
T2T-CHM13v2.01073,087,082 - 73,106,898 (+)NCBIT2T-CHM13v2.0
Anapc16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391059,823,730 - 59,838,935 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1059,823,231 - 59,838,957 (-)EnsemblGRCm39 Ensembl
GRCm381059,987,409 - 60,003,135 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1059,987,409 - 60,003,135 (-)EnsemblGRCm38mm10GRCm38
MGSCv371059,450,657 - 59,465,860 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361059,383,266 - 59,398,469 (-)NCBIMGSCv36mm8
Celera1061,085,094 - 61,100,402 (-)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.66NCBI
Anapc16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543719,367,662 - 19,381,603 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543719,367,662 - 19,381,607 (-)NCBIChiLan1.0ChiLan1.0
ANAPC16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2884,366,537 - 84,384,361 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11084,371,858 - 84,391,347 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01068,738,800 - 68,758,677 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11071,206,662 - 71,224,186 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1071,206,662 - 71,224,186 (+)Ensemblpanpan1.1panPan2
ANAPC16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1422,860,893 - 22,889,249 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl422,876,631 - 22,888,882 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha422,996,918 - 23,025,486 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0423,140,144 - 23,169,201 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl423,155,500 - 23,170,126 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1423,041,473 - 23,070,216 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0423,241,967 - 23,270,950 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0423,595,751 - 23,624,506 (+)NCBIUU_Cfam_GSD_1.0
Anapc16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721358,187,775 - 58,203,952 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365216,678,755 - 6,697,488 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365216,680,119 - 6,696,661 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANAPC16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1475,082,740 - 75,093,074 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11475,082,673 - 75,093,078 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21481,089,430 - 81,099,835 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANAPC16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1959,076,800 - 59,096,000 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl959,074,739 - 59,096,432 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604819,712,879 - 19,732,491 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Anapc16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247546,009,151 - 6,023,908 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247546,009,255 - 6,031,023 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Anapc16
54 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:119
Count of miRNA genes:85
Interacting mature miRNAs:106
Transcripts:ENSRNOT00000000702
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat

Markers in Region
RH134743  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22027,927,589 - 27,927,794 (+)MAPPERmRatBN7.2
Rnor_6.02029,544,882 - 29,545,086NCBIRnor6.0
Rnor_5.02031,350,230 - 31,350,434UniSTSRnor5.0
RGSC_v3.42027,287,873 - 27,288,077UniSTSRGSC3.4
Celera2029,368,891 - 29,369,095UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 52 36 19 36 8 11 74 35 41 11 8
Low 5 5 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000000702   ⟹   ENSRNOP00000000702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2027,927,334 - 27,941,984 (-)Ensembl
Rnor_6.0 Ensembl2029,544,629 - 29,558,321 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114556   ⟹   ENSRNOP00000093626
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2027,927,334 - 27,941,653 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119488   ⟹   ENSRNOP00000093739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2027,927,337 - 27,941,984 (-)Ensembl
RefSeq Acc Id: NM_001399607   ⟹   NP_001386536
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82028,470,282 - 28,484,589 (-)NCBI
mRatBN7.22027,927,334 - 27,941,644 (-)NCBI
RefSeq Acc Id: NM_001399608   ⟹   NP_001386537
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82028,470,282 - 28,484,589 (-)NCBI
mRatBN7.22027,927,334 - 27,941,644 (-)NCBI
RefSeq Acc Id: NM_001399609   ⟹   NP_001386538
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82028,470,282 - 28,484,589 (-)NCBI
mRatBN7.22027,927,334 - 27,941,644 (-)NCBI
RefSeq Acc Id: XM_063278908   ⟹   XP_063134978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82028,470,282 - 28,484,601 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000000702   ⟸   ENSRNOT00000000702
RefSeq Acc Id: ENSRNOP00000093626   ⟸   ENSRNOT00000114556
RefSeq Acc Id: ENSRNOP00000093739   ⟸   ENSRNOT00000119488
RefSeq Acc Id: NP_001386536   ⟸   NM_001399607
- Peptide Label: isoform 1
- UniProtKB: A6K3W1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386537   ⟸   NM_001399608
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001386538   ⟸   NM_001399609
- Peptide Label: isoform 3
- UniProtKB: A0A8I6AKF1 (UniProtKB/TrEMBL),   A6K3W0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063134978   ⟸   XM_063278908
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDN9-F1-model_v2 AlphaFold D3ZDN9 1-129 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2321124 AgrOrtholog
BioCyc Gene G2FUF-3750 BioCyc
Ensembl Genes ENSRNOG00000000576 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000000702.7 UniProtKB/TrEMBL
  ENSRNOT00000114556 ENTREZGENE
  ENSRNOT00000114556.1 UniProtKB/TrEMBL
  ENSRNOT00000119488.1 UniProtKB/TrEMBL
InterPro APC16 UniProtKB/TrEMBL
KEGG Report rno:100360936 UniProtKB/TrEMBL
NCBI Gene 100360936 ENTREZGENE
PANTHER ANAPHASE-PROMOTING COMPLEX SUBUNIT 16 UniProtKB/TrEMBL
  PTHR31564 UniProtKB/TrEMBL
Pfam ANAPC16 UniProtKB/TrEMBL
PhenoGen Anapc16 PhenoGen
RatGTEx ENSRNOG00000000576 RatGTEx
UniProt A0A8I6AKF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AXG3_RAT UniProtKB/TrEMBL
  A6K3W0 ENTREZGENE, UniProtKB/TrEMBL
  A6K3W1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDN9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-09 Anapc16  anaphase promoting complex subunit 16  LOC100360936  rCG22080-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100360936  rCG22080-like      Symbol and Name status set to provisional 70820 PROVISIONAL