Gene: Cdh22 (cadherin 22) Rattus norvegicus
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Symbol:
Cdh22
Name:
cadherin 22
RGD ID:
2321
Description:
Predicted to enable beta-catenin binding activity and cadherin binding activity. Involved in calcium-dependent cell-cell adhesion. Predicted to be located in plasma membrane. Predicted to be part of catenin complex. Predicted to be active in adherens junction. Orthologous to human CDH22 (cadherin 22); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 2-acetamidofluorene; 3,4-methylenedioxymethamphetamine.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Previously known as:
cadherin-22; PB-cadherin; pituitary and brain cadherin
RGD Orthologs
Alliance Orthologs
More Info
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More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
CDH22 (cadherin 22)
HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Cdh22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Cdh22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
CDH22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
CDH22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Cdh22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
CDH22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
CDH22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Cdh22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Cdh22 (cadherin 22)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
CDH22 (cadherin 22)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Cdh22 (cadherin 22)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
cdh22
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
cdh22
Alliance
DIOPT (OMA|OrthoFinder|PANTHER|PhylomeDB)
Drosophila melanogaster (fruit fly):
shg
Alliance
DIOPT (Ensembl Compara|InParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 174,264,869 - 174,389,940 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 3 174,264,869 - 174,390,142 (-) Ensembl GRCr8 mRatBN7.2 3 153,845,563 - 153,970,630 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 153,845,787 - 153,970,588 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 3 157,654,361 - 157,779,291 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 166,153,335 - 166,278,266 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 163,897,109 - 164,019,650 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Dahl_SR_JrHsd 3 172,353,854 - 172,476,380 (-) NCBI Dahl_SR_JrHsd Lyon_Normotensive 3 179,214,758 - 179,337,286 (-) NCBI Lyon_Normotensive Lyon_Hypertensive 3 171,181,982 - 171,304,506 (-) NCBI Lyon_Hypertensive F344_StmMcwi 3 152,078,625 - 152,201,157 (-) NCBI F344_StmMcwi Rnor_6.0 3 161,574,993 - 161,971,102 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 161,575,631 - 161,917,285 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 3 167,759,873 - 168,153,365 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 3 156,155,004 - 156,275,540 (-) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 3 152,449,958 - 152,516,313 (-) NCBI Celera RGSC_v3.1 6 134,126,192 - 134,128,100 (+) NCBI Cytogenetic Map 3 q42 NCBI
JBrowse:
Imported Disease Annotations - CTD
Only show annotations with direct experimental evidence (0 objects hidden)
Cdh22 Rat 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO Cdh22 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cdh22 Rat 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine decreases expression EXP 6480464 chlorcyclizine results in decreased expression of CDH22 mRNA CTD PMID:21058326 Cdh22 Rat 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Cdh22 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cdh22 Rat 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO Cdh22 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cdh22 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Cdh22 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CDH22 mRNA CTD PMID:21570461|PMID:26377647 Cdh22 Rat 2,4,4'-trichlorobiphenyl multiple interactions ISO Cdh22 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cdh22 Rat 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of CDH22 mRNA CTD PMID:17187413 Cdh22 Rat 3,4-methylenedioxymethamphetamine increases expression ISO Cdh22 (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CDH22 mRNA CTD PMID:20188158 Cdh22 Rat 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of CDH22 mRNA CTD PMID:30071829 Cdh22 Rat 4,4'-sulfonyldiphenol affects methylation ISO Cdh22 (Mus musculus) 6480464 bisphenol S affects the methylation of CDH22 exon; bisphenol S affects the methylation of CDH22 more ... CTD PMID:31683443|PMID:33297965 Cdh22 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of CDH22 mRNA CTD PMID:24780913|PMID:25825206 Cdh22 Rat 8-Br-cAMP decreases expression ISO CDH22 (Homo sapiens) 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CDH22 mRNA CTD PMID:22079614 Cdh22 Rat aflatoxin B1 decreases methylation ISO CDH22 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of CDH22 gene CTD PMID:27153756 Cdh22 Rat aflatoxin B1 increases methylation ISO CDH22 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of CDH22 intron CTD PMID:30157460 Cdh22 Rat allethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 Cdh22 Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of CDH22 mRNA CTD PMID:16483693 Cdh22 Rat amosite asbestos decreases methylation ISO CDH22 (Homo sapiens) 6480464 Asbestos, Amosite results in decreased methylation of CDH22 promoter CTD PMID:29626692 Cdh22 Rat benzo[a]pyrene decreases methylation ISO CDH22 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of CDH22 promoter CTD PMID:27901495 Cdh22 Rat benzo[a]pyrene affects methylation ISO CDH22 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of CDH22 exon CTD PMID:27901495 Cdh22 Rat benzo[a]pyrene decreases methylation ISO Cdh22 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of CDH22 intron CTD PMID:27901495 Cdh22 Rat benzo[b]fluoranthene decreases expression ISO Cdh22 (Mus musculus) 6480464 benzo(b)fluoranthene results in decreased expression of CDH22 mRNA CTD PMID:26377693 Cdh22 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CDH22 mRNA CTD PMID:25181051 Cdh22 Rat bisphenol A increases expression ISO Cdh22 (Mus musculus) 6480464 bisphenol A results in increased expression of CDH22 mRNA CTD PMID:32156529 Cdh22 Rat bisphenol A multiple interactions ISO CDH22 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CDH22 gene CTD PMID:31601247 Cdh22 Rat bisphenol A decreases methylation ISO CDH22 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of CDH22 gene CTD PMID:31601247 Cdh22 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CDH22 mRNA CTD PMID:34973380 Cdh22 Rat Butylbenzyl phthalate affects methylation ISO Cdh22 (Mus musculus) 6480464 butylbenzyl phthalate affects the methylation of CDH22 intron CTD PMID:28392331 Cdh22 Rat Butylbenzyl phthalate increases methylation ISO Cdh22 (Mus musculus) 6480464 butylbenzyl phthalate results in increased methylation of CDH22 5' UTR CTD PMID:28392331 Cdh22 Rat cadmium atom multiple interactions ISO Cdh22 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CDH22 more ... CTD PMID:37325564 Cdh22 Rat cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CDH22 more ... CTD PMID:39012411 Cdh22 Rat cadmium dichloride multiple interactions ISO Cdh22 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CDH22 more ... CTD PMID:37325564 Cdh22 Rat cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CDH22 more ... CTD PMID:39012411 Cdh22 Rat carbon nanotube decreases expression ISO Cdh22 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of CDH22 mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Cdh22 Rat CGP 52608 multiple interactions ISO CDH22 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to CDH22 gene] CTD PMID:28238834 Cdh22 Rat chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of CDH22 mRNA CTD PMID:23125180 Cdh22 Rat chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of CDH22 mRNA CTD PMID:20691718 Cdh22 Rat choline multiple interactions ISO Cdh22 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... CTD PMID:20938992 Cdh22 Rat crocidolite asbestos decreases methylation ISO CDH22 (Homo sapiens) 6480464 Asbestos, Crocidolite results in decreased methylation of CDH22 promoter CTD PMID:29626692 Cdh22 Rat cyhalothrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 Cdh22 Rat cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 Cdh22 Rat dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA CTD PMID:18636392 Cdh22 Rat diuron decreases expression EXP 6480464 Diuron results in decreased expression of CDH22 mRNA CTD PMID:25152437 Cdh22 Rat epoxiconazole decreases expression ISO Cdh22 (Mus musculus) 6480464 epoxiconazole results in decreased expression of CDH22 mRNA CTD PMID:35436446 Cdh22 Rat ethanol increases expression ISO Cdh22 (Mus musculus) 6480464 Ethanol results in increased expression of CDH22 mRNA CTD PMID:30319688 Cdh22 Rat ethanol affects expression ISO Cdh22 (Mus musculus) 6480464 Ethanol affects the expression of CDH22 mRNA CTD PMID:30319688 Cdh22 Rat fenvalerate multiple interactions EXP 6480464 [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] results in more ... CTD PMID:34896426 Cdh22 Rat folic acid multiple interactions ISO Cdh22 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... CTD PMID:20938992 Cdh22 Rat fulvestrant multiple interactions ISO CDH22 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of CDH22 gene CTD PMID:31601247 Cdh22 Rat genistein decreases expression EXP 6480464 Genistein results in decreased expression of CDH22 mRNA CTD PMID:17341692 Cdh22 Rat glyphosate affects methylation EXP 6480464 Glyphosate affects the methylation of CDH22 gene CTD PMID:35440735 Cdh22 Rat L-ascorbic acid increases expression EXP 6480464 Ascorbic Acid results in increased expression of CDH22 mRNA CTD PMID:15372504 Cdh22 Rat L-methionine multiple interactions ISO Cdh22 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... CTD PMID:20938992 Cdh22 Rat lipopolysaccharide multiple interactions ISO CDH22 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of CDH22 mRNA CTD PMID:35811015 Cdh22 Rat methoxychlor affects methylation EXP 6480464 Methoxychlor affects the methylation of CDH22 gene CTD PMID:35440735 Cdh22 Rat morphine increases expression ISO Cdh22 (Mus musculus) 6480464 Morphine results in increased expression of CDH22 mRNA CTD PMID:21178816 Cdh22 Rat N-methyl-N-nitrosourea decreases expression EXP 6480464 Methylnitrosourea results in decreased expression of CDH22 mRNA CTD PMID:17341692 Cdh22 Rat ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] affects the expression of CDH22 mRNA CTD PMID:18636392 Cdh22 Rat ozone increases expression EXP 6480464 Ozone results in increased expression of CDH22 mRNA CTD PMID:26667333 Cdh22 Rat PCB138 multiple interactions ISO Cdh22 (Mus musculus) 6480464 [2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ... CTD PMID:25510870 Cdh22 Rat perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CDH22 mRNA CTD PMID:20136073 Cdh22 Rat pyrethrins decreases expression EXP 6480464 Pyrethrins results in decreased expression of CDH22 protein CTD PMID:34896426 Cdh22 Rat resveratrol multiple interactions ISO CDH22 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CDH22 mRNA CTD PMID:23557933 Cdh22 Rat S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO CDH22 (Homo sapiens) 6480464 S-(1,2-dichlorovinyl)cysteine results in decreased expression of CDH22 mRNA CTD PMID:35811015 Cdh22 Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO CDH22 (Homo sapiens) 6480464 [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of CDH22 mRNA CTD PMID:35811015 Cdh22 Rat silicon dioxide increases expression ISO CDH22 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of CDH22 mRNA CTD PMID:23806026 Cdh22 Rat silicon dioxide decreases methylation ISO CDH22 (Homo sapiens) 6480464 Silicon Dioxide results in decreased methylation of CDH22 gene CTD PMID:34973136 Cdh22 Rat silver atom decreases expression ISO Cdh22 (Mus musculus) 6480464 Silver results in decreased expression of CDH22 mRNA CTD PMID:27131904 Cdh22 Rat silver(0) decreases expression ISO Cdh22 (Mus musculus) 6480464 Silver results in decreased expression of CDH22 mRNA CTD PMID:27131904 Cdh22 Rat sodium arsenite affects methylation ISO CDH22 (Homo sapiens) 6480464 sodium arsenite affects the methylation of CDH22 gene CTD PMID:28589171 Cdh22 Rat sodium arsenite increases expression ISO CDH22 (Homo sapiens) 6480464 sodium arsenite results in increased expression of CDH22 mRNA CTD PMID:38568856 Cdh22 Rat Soman increases expression EXP 6480464 Soman results in increased expression of CDH22 mRNA CTD PMID:19281266 Cdh22 Rat testosterone increases expression ISO CDH22 (Homo sapiens) 6480464 Testosterone results in increased expression of CDH22 mRNA CTD PMID:33359661 Cdh22 Rat titanium dioxide decreases methylation ISO Cdh22 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of CDH22 gene CTD PMID:35295148 Cdh22 Rat trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of CDH22 gene CTD PMID:27618143 Cdh22 Rat trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of CDH22 mRNA CTD PMID:33387578 Cdh22 Rat triptonide increases expression ISO Cdh22 (Mus musculus) 6480464 triptonide results in increased expression of CDH22 mRNA CTD PMID:33045310 Cdh22 Rat troglitazone increases expression ISO CDH22 (Homo sapiens) 6480464 troglitazone results in increased expression of CDH22 mRNA CTD PMID:28934090 Cdh22 Rat tunicamycin decreases expression ISO Cdh22 (Mus musculus) 6480464 Tunicamycin results in decreased expression of CDH22 mRNA CTD PMID:17127020 Cdh22 Rat undecane increases expression EXP 6480464 undecane results in increased expression of CDH22 protein CTD PMID:17337753 Cdh22 Rat valproic acid affects expression ISO CDH22 (Homo sapiens) 6480464 Valproic Acid affects the expression of CDH22 mRNA CTD PMID:25979313 Cdh22 Rat venlafaxine hydrochloride affects expression EXP 6480464 Venlafaxine Hydrochloride affects the expression of CDH22 mRNA CTD PMID:25423262 Cdh22 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of CDH22 mRNA CTD PMID:19015723