Prmt1l1 (protein arginine methyltransferase 1 like 1) - Rat Genome Database

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Gene: Prmt1l1 (protein arginine methyltransferase 1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Prmt1l1
Name: protein arginine methyltransferase 1 like 1
RGD ID: 2320935
Description: Predicted to enable histone methyltransferase activity; protein-arginine omega-N asymmetric methyltransferase activity; and protein-arginine omega-N monomethyltransferase activity. Predicted to be involved in chromatin remodeling and regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human PRMT1 (protein arginine methyltransferase 1).
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: MODEL
Previously known as: LOC100361025; protein arginine methyltransferase 1-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81491,764,602 - 91,765,863 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1491,764,754 - 91,765,815 (-)EnsemblGRCr8
mRatBN7.21487,551,165 - 87,552,305 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1487,551,207 - 87,552,294 (-)EnsemblmRatBN7.2
Rnor_6.01493,040,967 - 93,042,219 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1493,040,982 - 93,042,182 (-)Ensemblrn6Rnor6.0
Rnor_5.01492,831,775 - 92,833,028 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41493,881,125 - 93,882,381 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1486,680,943 - 86,682,195 (-)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
methylation  (IEA)

Cellular Component
cytosol  (IEA)
nucleoplasm  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Prmt1l1
5 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:95
Count of miRNA genes:80
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000005432
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat

Markers in Region
BI285876  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,458,857 - 95,459,077 (+)MAPPERmRatBN7.2
mRatBN7.21487,551,063 - 87,551,283 (+)MAPPERmRatBN7.2
Rnor_6.01100,971,137 - 100,971,356NCBIRnor6.0
Rnor_6.01493,040,983 - 93,041,202NCBIRnor6.0
Rnor_5.01492,831,791 - 92,832,010UniSTSRnor5.0
Rnor_5.01102,035,577 - 102,035,796UniSTSRnor5.0
RGSC_v3.4195,449,062 - 95,449,281UniSTSRGSC3.4
RGSC_v3.41493,881,141 - 93,881,360UniSTSRGSC3.4
Celera1486,680,959 - 86,681,178UniSTS
Celera189,720,387 - 89,720,606UniSTS
RH 3.4 Map14654.09UniSTS
Cytogenetic Map1q22UniSTS
Hrmt1l2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21767,626,147 - 67,626,358 (+)MAPPERmRatBN7.2
mRatBN7.21487,552,031 - 87,552,243 (+)MAPPERmRatBN7.2
Rnor_6.01493,041,951 - 93,042,162NCBIRnor6.0
Rnor_6.01771,397,715 - 71,397,925NCBIRnor6.0
Rnor_5.01773,092,124 - 73,092,334UniSTSRnor5.0
Rnor_5.01492,832,759 - 92,832,970UniSTSRnor5.0
RGSC_v3.41493,882,109 - 93,882,320UniSTSRGSC3.4
RGSC_v3.41778,879,926 - 78,880,136UniSTSRGSC3.4
Celera1767,123,381 - 67,123,591UniSTS
Celera1486,681,927 - 86,682,138UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 67 161 91 90 59 86 59 6 349 185 10 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000005432   ⟹   ENSRNOP00000075012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1491,764,754 - 91,765,815 (-)Ensembl
mRatBN7.2 Ensembl1487,551,207 - 87,552,294 (-)Ensembl
Rnor_6.0 Ensembl1493,040,982 - 93,042,182 (-)Ensembl
RefSeq Acc Id: XM_039092860   ⟹   XP_038948788
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81491,764,602 - 91,765,863 (-)NCBI
mRatBN7.21487,551,165 - 87,552,305 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038948788 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063624.3
Ensembl Acc Id: ENSRNOP00000075012   ⟸   ENSRNOT00000005432
RefSeq Acc Id: XP_038948788   ⟸   XM_039092860
- UniProtKB: A0A8L2QUM0 (UniProtKB/TrEMBL)
Protein Domains
Methyltransferase   Protein arginine N-methyltransferase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K9I8-F1-model_v2 AlphaFold A0A0G2K9I8 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699497
Promoter ID:EPDNEW_R10020
Type:multiple initiation site
Name:LOC100361025_1
Description:protein arginine methyltransferase 1-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01493,042,195 - 93,042,255EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2320935 AgrOrtholog
BioCyc Gene G2FUF-14967 BioCyc
Ensembl Genes ENSRNOG00000004090 Ensembl
  ENSRNOG00000026109 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064272.5 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
  Hnrnp arginine n-methyltransferase1 UniProtKB/TrEMBL
InterPro Arg_MeTrfase UniProtKB/TrEMBL
  Methyltransf_25 UniProtKB/TrEMBL
  PRMT_dom UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene 100361025 ENTREZGENE
PANTHER PROTEIN ARGININE N-METHYLTRANSFERASE 1 UniProtKB/TrEMBL
  PTHR11006 UniProtKB/TrEMBL
Pfam Methyltransf_25 UniProtKB/TrEMBL
  PRMT_C UniProtKB/TrEMBL
PhenoGen Prmt1l1 PhenoGen
PROSITE SAM_MT_PRMT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004090 RatGTEx
  ENSRNOG00000026109 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8L2QUM0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Prmt1l1  protein arginine methyltransferase 1 like 1  LOC100361025  protein arginine methyltransferase 1-like  Symbol and Name Changed 1299863 APPROVED
2010-05-05 LOC100361025  protein arginine methyltransferase 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL