Ralgps1 (Ral GEF with PH domain and SH3 binding motif 1) - Rat Genome Database

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Pathways
Gene: Ralgps1 (Ral GEF with PH domain and SH3 binding motif 1) Rattus norvegicus
Analyze
Symbol: Ralgps1
Name: Ral GEF with PH domain and SH3 binding motif 1
RGD ID: 2319500
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction and regulation of Ral protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human RALGPS1 (Ral GEF with PH domain and SH3 binding motif 1); INTERACTS WITH 1-naphthyl isothiocyanate; 3,3',4,4',5-pentachlorobiphenyl; endosulfan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100361774; ras-specific guanine nucleotide-releasing factor RalGPS1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,831,029 - 37,067,659 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl336,831,029 - 37,067,659 (-)EnsemblGRCr8
mRatBN7.2316,433,323 - 16,670,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,433,742 - 16,669,972 (-)EnsemblmRatBN7.2
Rnor_6.0312,182,722 - 12,415,081 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl312,178,853 - 12,415,073 (-)Ensemblrn6Rnor6.0
Rnor_5.0317,516,513 - 17,748,437 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4312,146,421 - 12,379,365 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera311,175,322 - 11,407,978 (-)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10747847  


Genomics

Comparative Map Data
Ralgps1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,831,029 - 37,067,659 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl336,831,029 - 37,067,659 (-)EnsemblGRCr8
mRatBN7.2316,433,323 - 16,670,276 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl316,433,742 - 16,669,972 (-)EnsemblmRatBN7.2
Rnor_6.0312,182,722 - 12,415,081 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl312,178,853 - 12,415,073 (-)Ensemblrn6Rnor6.0
Rnor_5.0317,516,513 - 17,748,437 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4312,146,421 - 12,379,365 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera311,175,322 - 11,407,978 (-)NCBICelera
Cytogenetic Map3p11NCBI
RALGPS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389126,914,782 - 127,223,166 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9126,914,774 - 127,223,166 (+)Ensemblhg38GRCh38
GRCh379129,677,061 - 129,985,445 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369128,716,874 - 129,025,264 (+)NCBIBuild 36Build 36hg18NCBI36
Build 349126,756,606 - 127,064,997NCBI
Celera9100,331,657 - 100,640,072 (+)NCBICelera
Cytogenetic Map9q33.3NCBI
HuRef999,292,239 - 99,601,281 (+)NCBIHuRef
CHM1_19129,827,752 - 130,136,105 (+)NCBICHM1_1
T2T-CHM13v2.09139,121,232 - 139,429,610 (+)NCBIT2T-CHM13v2.0
Ralgps1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39233,023,431 - 33,261,569 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl233,023,429 - 33,261,498 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38233,133,419 - 33,371,499 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl233,133,417 - 33,371,486 (-)Ensemblmm10GRCm38
MGSCv37232,992,493 - 33,226,998 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36232,958,982 - 33,193,487 (-)NCBIMGSCv36mm8
Celera232,844,107 - 33,078,710 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.25NCBI
Ralgps1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554191,334,627 - 1,594,192 (-)Ensembl
ChiLan1.0NW_0049554191,334,627 - 1,593,828 (-)NCBIChiLan1.0ChiLan1.0
RALGPS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21112,132,099 - 12,441,702 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1912,134,445 - 12,444,046 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,033,100 - 98,342,582 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19126,689,589 - 126,997,020 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9126,689,557 - 126,992,628 (+)EnsemblpanPan2panpan1.1
RALGPS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1956,079,838 - 56,374,986 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl956,083,858 - 56,374,539 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha955,283,525 - 55,578,317 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0957,001,704 - 57,297,096 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl957,006,128 - 57,297,216 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,761,149 - 56,055,967 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0956,076,300 - 56,371,306 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0956,167,390 - 56,462,826 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ralgps1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,001,260 - 195,235,728 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648714,769,821 - 15,004,257 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648714,769,527 - 15,004,214 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGPS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1267,480,750 - 267,770,440 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11267,437,066 - 267,770,444 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21301,369,460 - 301,684,026 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGPS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,913,054 - 11,215,877 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660795,000,317 - 5,303,960 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgps1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247608,236,803 - 8,499,285 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247608,236,803 - 8,499,351 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ralgps1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v152,265,024 - 2,499,438 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ralgps1
1397 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:308
Count of miRNA genes:144
Interacting mature miRNAs:167
Transcripts:ENSRNOT00000022755, ENSRNOT00000045724, ENSRNOT00000065544, ENSRNOT00000066922
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
11528620Bss113Bone structure and strength QTL 1139.752e-10femur morphology trait (VT:0000559)femoral neck width (CMO:0001695)33688834239639105Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat

Markers in Region
AW260363  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2316,547,699 - 16,547,822 (+)MAPPERmRatBN7.2
Rnor_6.0312,293,341 - 12,293,463NCBIRnor6.0
Rnor_5.0317,626,812 - 17,626,934UniSTSRnor5.0
RGSC_v3.4312,257,072 - 12,257,194UniSTSRGSC3.4
Celera311,285,771 - 11,285,893UniSTS
AA819180  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2316,547,771 - 16,547,967 (+)MAPPERmRatBN7.2
Rnor_6.0312,293,413 - 12,293,608NCBIRnor6.0
Rnor_5.0317,626,884 - 17,627,079UniSTSRnor5.0
RGSC_v3.4312,257,144 - 12,257,339UniSTSRGSC3.4
Celera311,285,843 - 11,286,038UniSTS
RH 3.4 Map384.2UniSTS
G46130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2316,614,239 - 16,614,441 (+)MAPPERmRatBN7.2
Rnor_6.0312,471,356 - 12,471,557NCBIRnor6.0
Rnor_5.0317,804,045 - 17,804,246UniSTSRnor5.0
RGSC_v3.4312,323,923 - 12,324,124UniSTSRGSC3.4
Celera311,352,267 - 11,352,468UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 355 192 11 141 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006224361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006234020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106206 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000022755   ⟹   ENSRNOP00000022755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,831,029 - 37,067,659 (-)Ensembl
mRatBN7.2 Ensembl316,433,742 - 16,669,972 (-)Ensembl
Rnor_6.0 Ensembl312,178,853 - 12,415,073 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094995   ⟹   ENSRNOP00000081013
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,831,029 - 37,067,659 (-)Ensembl
mRatBN7.2 Ensembl316,433,742 - 16,669,972 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099643   ⟹   ENSRNOP00000083442
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,831,029 - 37,067,659 (-)Ensembl
mRatBN7.2 Ensembl316,433,742 - 16,669,972 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105613   ⟹   ENSRNOP00000082954
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,831,029 - 37,067,659 (-)Ensembl
mRatBN7.2 Ensembl316,433,742 - 16,669,972 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000169370   ⟹   ENSRNOP00000108818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl336,836,958 - 37,067,659 (-)Ensembl
RefSeq Acc Id: NM_001427068   ⟹   NP_001413997
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,659 (-)NCBI
RefSeq Acc Id: XM_006234015   ⟹   XP_006234077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,275 (-)NCBI
Rnor_6.0312,185,751 - 12,415,081 (-)NCBI
Rnor_5.0317,516,513 - 17,748,437 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234019   ⟹   XP_006234081
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,269 (-)NCBI
Rnor_6.0312,185,751 - 12,415,080 (-)NCBI
Rnor_5.0317,516,513 - 17,748,437 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006234020   ⟹   XP_006234082
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,265 (-)NCBI
Rnor_6.0312,182,723 - 12,415,080 (-)NCBI
Rnor_5.0317,516,513 - 17,748,437 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761789   ⟹   XP_008760011
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,270 (-)NCBI
Rnor_6.0312,185,751 - 12,415,080 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008761790   ⟹   XP_008760012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,266 (-)NCBI
Rnor_6.0312,182,723 - 12,415,080 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592120   ⟹   XP_017447609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,276 (-)NCBI
Rnor_6.0312,185,751 - 12,415,081 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592121   ⟹   XP_017447610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,276 (-)NCBI
Rnor_6.0312,182,722 - 12,415,081 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592122   ⟹   XP_017447611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,272 (-)NCBI
Rnor_6.0312,182,722 - 12,415,080 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106205   ⟹   XP_038962133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
mRatBN7.2316,433,323 - 16,670,274 (-)NCBI
RefSeq Acc Id: XM_039106206   ⟹   XP_038962134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,033,528 (-)NCBI
mRatBN7.2316,433,323 - 16,635,840 (-)NCBI
RefSeq Acc Id: XM_039106207   ⟹   XP_038962135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,007,265 (-)NCBI
mRatBN7.2316,433,323 - 16,609,575 (-)NCBI
RefSeq Acc Id: XM_039106209   ⟹   XP_038962137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 36,978,517 (-)NCBI
mRatBN7.2316,433,323 - 16,580,832 (-)NCBI
RefSeq Acc Id: XM_063282955   ⟹   XP_063139025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,831,029 - 37,067,579 (-)NCBI
RefSeq Acc Id: XM_063282957   ⟹   XP_063139027
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,840,745 - 37,067,579 (-)NCBI
RefSeq Acc Id: XM_063282958   ⟹   XP_063139028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,855,299 - 37,067,579 (-)NCBI
RefSeq Acc Id: XR_005502083
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,838,698 - 37,067,579 (-)NCBI
mRatBN7.2316,440,946 - 16,670,272 (-)NCBI
RefSeq Acc Id: XR_005502084
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,838,698 - 37,067,579 (-)NCBI
mRatBN7.2316,441,001 - 16,670,272 (-)NCBI
RefSeq Acc Id: XR_005502086
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,842,747 - 37,067,579 (-)NCBI
mRatBN7.2316,445,059 - 16,670,272 (-)NCBI
RefSeq Acc Id: XR_005502087
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,838,698 - 37,067,579 (-)NCBI
mRatBN7.2316,440,946 - 16,670,265 (-)NCBI
RefSeq Acc Id: XP_006234082   ⟸   XM_006234020
- Peptide Label: isoform X10
- UniProtKB: A0A8I6G5E3 (UniProtKB/TrEMBL),   A0A8I5ZWL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234077   ⟸   XM_006234015
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234081   ⟸   XM_006234019
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZWL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760012   ⟸   XM_008761790
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZWL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008760011   ⟸   XM_008761789
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZWL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447610   ⟸   XM_017592121
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447611   ⟸   XM_017592122
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447609   ⟸   XM_017592120
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000022755   ⟸   ENSRNOT00000022755
RefSeq Acc Id: XP_038962133   ⟸   XM_039106205
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962134   ⟸   XM_039106206
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962135   ⟸   XM_039106207
- Peptide Label: isoform X12
- UniProtKB: A6JUA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962137   ⟸   XM_039106209
- Peptide Label: isoform X12
- UniProtKB: A6JUA4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083442   ⟸   ENSRNOT00000099643
Ensembl Acc Id: ENSRNOP00000081013   ⟸   ENSRNOT00000094995
Ensembl Acc Id: ENSRNOP00000082954   ⟸   ENSRNOT00000105613
RefSeq Acc Id: NP_001413997   ⟸   NM_001427068
- UniProtKB: D3ZLR4 (UniProtKB/TrEMBL),   A0A8I5ZUI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139025   ⟸   XM_063282955
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZUI1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139027   ⟸   XM_063282957
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063139028   ⟸   XM_063282958
- Peptide Label: isoform X14
Ensembl Acc Id: ENSRNOP00000108818   ⟸   ENSRNOT00000169370
Protein Domains
PH   Ras-GEF

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLR4-F1-model_v2 AlphaFold D3ZLR4 1-585 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692012
Promoter ID:EPDNEW_R2526
Type:single initiation site
Name:Ralgps1_1
Description:Ral GEF with PH domain and SH3 binding motif 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0312,415,071 - 12,415,131EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2319500 AgrOrtholog
BioCyc Gene G2FUF-50108 BioCyc
Ensembl Genes ENSRNOG00000016910 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022755 ENTREZGENE
  ENSRNOT00000022755.7 UniProtKB/TrEMBL
  ENSRNOT00000094995 ENTREZGENE
  ENSRNOT00000094995.2 UniProtKB/TrEMBL
  ENSRNOT00000099643 ENTREZGENE
  ENSRNOT00000099643.2 UniProtKB/TrEMBL
  ENSRNOT00000105613.2 UniProtKB/TrEMBL
  ENSRNOT00000169370 ENTREZGENE
  ENSRNOT00000169370.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras_GEF_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
  RasGRF_CDC25 UniProtKB/TrEMBL
NCBI Gene 100361774 ENTREZGENE
PANTHER PTHR23113 UniProtKB/TrEMBL
  RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1 UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
PhenoGen Ralgps1 PhenoGen
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016910 RatGTEx
SMART RasGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Ras_GEF UniProtKB/TrEMBL
UniProt A0A8I5ZUI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWL1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G5E3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LDJ8_RAT UniProtKB/TrEMBL
  A6JUA4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZLR4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-08-22 Ralgps1  Ral GEF with PH domain and SH3 binding motif 1  LOC100361774  Ral GEF with PH domain and SH3 binding motif 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361774  Ral GEF with PH domain and SH3 binding motif 1      Symbol and Name status set to provisional 70820 PROVISIONAL