RT1-A (RT1 class I, locus A) - Rat Genome Database

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Gene: RT1-A (RT1 class I, locus A) Rattus norvegicus
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Symbol: RT1-A
Name: RT1 class I, locus A
RGD ID: 2300147
Description: Predicted to be involved in antigen processing and presentation of peptide antigen via MHC class I and immune response. Predicted to be located in lumenal side of endoplasmic reticulum membrane and phagocytic vesicle membrane. Predicted to be part of MHC class I protein complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC188489; MHC class I RT1.Aa alpha-chain; RT1 class I gene(A); RT1 class I histocompatibility antigen, AA alpha chain; RT1-region, class I (A); Rt1.aa; RTA
Latest Assembly: GRCr8 - GRCr8 Assembly
NCBI Annotation Information: Genome Annotation Status: not in current annotation release
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map20 NCBI



References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2315309   PMID:9443915   PMID:10970097   PMID:12470953   PMID:12477932   PMID:19882666   PMID:23662467  


Genomics

Markers in Region
BI280335  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8203,381,615 - 3,381,769 (+)Marker Load Pipeline
mRatBN7.2203,376,937 - 3,377,091 (+)MAPPERmRatBN7.2
Rnor_6.020154,311 - 154,464NCBIRnor6.0
Rnor_5.020155,493 - 155,646UniSTSRnor5.0
RGSC_v3.4203,471,812 - 3,471,965UniSTSRGSC3.4
RH 3.4 Map2052.32UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression


Sequence


Protein Sequences
Protein RefSeqs NP_001128173 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66751 (Get FASTA)   NCBI Sequence Viewer  
  CAA74333 (Get FASTA)   NCBI Sequence Viewer  
  P16391 (Get FASTA)   NCBI Sequence Viewer  
Protein Domains
Ig-like   Ig-like C1-type   MHC class I-like antigen recognition-like


Additional Information

Database Acc Id Source(s)
Gene3D-CATH Immunoglobulins UniProtKB/Swiss-Prot
  MHC class I-like antigen recognition-like UniProtKB/Swiss-Prot
InterPro Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig/MHC_CS UniProtKB/Swiss-Prot
  Ig_C1-set UniProtKB/Swiss-Prot
  MHC_class-I_related UniProtKB/Swiss-Prot
  MHC_I-like_Ag-recog UniProtKB/Swiss-Prot
  MHC_I-like_Ag-recog_sf UniProtKB/Swiss-Prot
  MHC_I/II-like_Ag-recog UniProtKB/Swiss-Prot
  MHC_I_a_a1/a2 UniProtKB/Swiss-Prot
  MHC_I_a_C UniProtKB/Swiss-Prot
NCBI Gene 100188935 ENTREZGENE
PANTHER HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, C ALPHA CHAIN UniProtKB/Swiss-Prot
  MHC CLASS I-RELATED UniProtKB/Swiss-Prot
Pfam C1-set UniProtKB/Swiss-Prot
  MHC_I UniProtKB/Swiss-Prot
  MHC_I_C UniProtKB/Swiss-Prot
PhenoGen RT1-A PhenoGen
PRINTS MHCCLASSI UniProtKB/Swiss-Prot
PROSITE IG_LIKE UniProtKB/Swiss-Prot
  IG_MHC UniProtKB/Swiss-Prot
SMART IGc1 UniProtKB/Swiss-Prot
Superfamily-SCOP Immunoglobulin UniProtKB/Swiss-Prot
  MHC antigen-recognition domain UniProtKB/Swiss-Prot
UniProt B2RYE7 ENTREZGENE, UniProtKB/TrEMBL
  HA12_RAT UniProtKB/Swiss-Prot
  O02940 ENTREZGENE
  P16391 ENTREZGENE
  Q9WUY3_RAT UniProtKB/TrEMBL
  Q9WUY4_RAT UniProtKB/TrEMBL
  Q9WUY5_RAT UniProtKB/TrEMBL
UniProt Secondary O02940 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-09-15 RT1-A  RT1 class I, locus A   Rt1.aa  MHC class I RT1.Aa alpha-chain  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-06 Rt1.aa  MHC class I RT1.Aa alpha-chain      Symbol and Name status set to provisional 70820 PROVISIONAL