Upk3bl1 (uroplakin 3B like 1) - Rat Genome Database

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Gene: Upk3bl1 (uroplakin 3B like 1) Rattus norvegicus
Analyze
Symbol: Upk3bl1
Name: uroplakin 3B like 1
RGD ID: 1598237
Description: Predicted to be active in membrane. Orthologous to human UPK3BL1 (uroplakin 3B like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; allopurinol; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC367994; LOC367994; similar to uroplakin 3B isoform b; Upk3bl; uroplakin 3B-like
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,246,960 - 26,252,973 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,246,960 - 26,252,973 (-)EnsemblGRCr8
mRatBN7.21220,610,353 - 20,616,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1220,610,353 - 20,616,366 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1221,750,697 - 21,756,694 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,363,406 - 22,369,403 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,428,579 - 21,434,612 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01223,654,996 - 23,661,009 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,654,996 - 23,661,009 (-)Ensemblrn6Rnor6.0
Rnor_5.01225,655,346 - 25,661,359 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41221,725,548 - 21,731,561 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,373,755 - 22,379,686 (-)NCBICelera
Cytogenetic Map12q12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Upk3bl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,246,960 - 26,252,973 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,246,960 - 26,252,973 (-)EnsemblGRCr8
mRatBN7.21220,610,353 - 20,616,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1220,610,353 - 20,616,366 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1221,750,697 - 21,756,694 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,363,406 - 22,369,403 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,428,579 - 21,434,612 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01223,654,996 - 23,661,009 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1223,654,996 - 23,661,009 (-)Ensemblrn6Rnor6.0
Rnor_5.01225,655,346 - 25,661,359 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41221,725,548 - 21,731,561 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,373,755 - 22,379,686 (-)NCBICelera
Cytogenetic Map12q12NCBI
UPK3BL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387102,637,025 - 102,642,791 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7102,637,025 - 102,642,856 (-)Ensemblhg38GRCh38
GRCh377102,277,472 - 102,283,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map7q22.1NCBI
HuRef743,909,208 - 43,914,626 (-)NCBIHuRef
CHM1_17102,108,491 - 102,114,259 (-)NCBICHM1_1
CRA_TCAGchr7v27101,637,841 - 101,643,607 (-)NCBI
Upk3bl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395136,086,114 - 136,105,549 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5136,083,346 - 136,093,180 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm385136,057,259 - 136,076,695 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5136,054,492 - 136,064,326 (+)Ensemblmm10GRCm38
MGSCv375136,533,137 - 136,540,194 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365136,333,802 - 136,348,951 (+)NCBIMGSCv36mm8
Celera5133,076,631 - 133,083,604 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.72NCBI
LOC117981060
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26120,546,150 - 120,559,206 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17168,810,324 - 168,823,757 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0794,674,526 - 94,699,000 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
UPK3BL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.167,662,674 - 7,666,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha69,357,769 - 9,361,484 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.067,482,805 - 7,486,520 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl67,482,808 - 7,486,519 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.167,451,444 - 7,455,157 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.067,414,493 - 7,418,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.067,578,084 - 7,581,799 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
UPK3BL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.139,847,585 - 9,871,319 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.239,640,324 - 9,645,773 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Upk3bl1
49 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:115
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000059451
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)122013902826430640Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 10 45 41 45 45 18 13 18 6 200 80 1 22 79 90 27 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000059451   ⟹   ENSRNOP00000056206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,246,960 - 26,252,973 (-)Ensembl
mRatBN7.2 Ensembl1220,610,353 - 20,616,366 (-)Ensembl
Rnor_6.0 Ensembl1223,654,996 - 23,661,009 (-)Ensembl
RefSeq Acc Id: NM_001109020   ⟹   NP_001102490
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,246,960 - 26,252,973 (-)NCBI
mRatBN7.21220,610,353 - 20,616,366 (-)NCBI
Rnor_6.01223,654,996 - 23,661,009 (-)NCBI
Rnor_5.01225,655,346 - 25,661,359 (-)NCBI
RGSC_v3.41221,725,548 - 21,731,561 (-)RGD
Celera1222,373,755 - 22,379,686 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102490 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM13329 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000056206
  ENSRNOP00000056206.3
RefSeq Acc Id: NP_001102490   ⟸   NM_001109020
- Peptide Label: precursor
- UniProtKB: D3ZXT5 (UniProtKB/TrEMBL),   A6J090 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056206   ⟸   ENSRNOT00000059451

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZXT5-F1-model_v2 AlphaFold D3ZXT5 1-250 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1598237 AgrOrtholog
BioCyc Gene G2FUF-19651 BioCyc
Ensembl Genes ENSRNOG00000038896 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000059451 ENTREZGENE
  ENSRNOT00000059451.4 UniProtKB/TrEMBL
InterPro Uroplakin-3 UniProtKB/TrEMBL
KEGG Report rno:367994 UniProtKB/TrEMBL
NCBI Gene 367994 ENTREZGENE
PANTHER PTHR15446 UniProtKB/TrEMBL
  PTHR15446:SF2 UniProtKB/TrEMBL
PhenoGen Upk3bl1 PhenoGen
RatGTEx ENSRNOG00000038896 RatGTEx
UniProt A6J090 ENTREZGENE, UniProtKB/TrEMBL
  D3ZXT5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-20 Upk3bl1  uroplakin 3B like 1  Upk3bl  uroplakin 3B-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Upk3bl  uroplakin 3B-like  LOC680969  similar to uroplakin 3B isoform b  Data merged from RGD:1585820 1643240 APPROVED
2011-01-24 Upk3bl  uroplakin 3B-like  LOC367994  similar to uroplakin 3B isoform b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC367994  similar to uroplakin 3B isoform b      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC680969  similar to uroplakin 3B isoform b      Symbol and Name status set to provisional 70820 PROVISIONAL